| Hexokinase 2 nonmetabolic function-mediated phosphorylation of IkappaBalpha enhances pancreatic ductal adenocarcinoma progression. | Hexokinase 2 nonmetabolic function-mediated phosphorylation of IκBα enhances pancreatic ductal adenocarcinoma progression.
Tong Y, Liu X, Wu L, Xiang Y, Wang J, Cheng Y, Zhang C, Han B, Wang L, Yan D., Free PMC Article | 09/17/2024 |
| RNA-binding protein SORBS2 increases human trophoblast cell migration via stabilizing HK2 mRNA in preeclampsia. | RNA-binding protein SORBS2 increases human trophoblast cell migration via stabilizing HK2 mRNA in preeclampsia.
Song L, Zhao X, Chen J, Yin H, Tang H, Li L, Dong H, Li X, Qu Z, Chu X, Guo M. | 08/15/2024 |
| CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis. | CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis.
Yu SK, Yu T, Wang YM, Sun A, Liu J, Lu KH., Free PMC Article | 08/9/2024 |
| HK2 and LDHA upregulation mediate hexavalent chromium-induced carcinogenesis, cancer development and prognosis through miR-218 inhibition. | HK2 and LDHA upregulation mediate hexavalent chromium-induced carcinogenesis, cancer development and prognosis through miR-218 inhibition.
Wang L, Zhang RK, Sang P, Xie YX, Zhang Y, Zhou ZH, Wang KK, Zhou FM, Ji XB, Liu WJ, Qiu JG, Jiang BH. | 06/17/2024 |
| Activation of the MEK/ERK Pathway Mediates the Inhibitory Effects of Silvestrol on Nasopharyngeal Carcinoma Cells via RAP1A, HK2, and GADD45A. | Activation of the MEK/ERK Pathway Mediates the Inhibitory Effects of Silvestrol on Nasopharyngeal Carcinoma Cells via RAP1A, HK2, and GADD45A.
Yu LR, Han XZ, Tang YZ, Liu D, Luo XQ, Qiu XW, Feng J, Yuan WX, Ding JY. | 05/24/2024 |
| The effect and mechanism of hexokinase-2 on cisplatin resistance in lung cancer cells A549. | The effect and mechanism of hexokinase-2 on cisplatin resistance in lung cancer cells A549.
Xie S, Li X, Zhao J, Zhang F, Shu Z, Cheng H, Liu S, Shi S. | 05/6/2024 |
| A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma. | A gain of function mutation in AKT1 increases hexokinase 2 and diminishes oxidative stress in meningioma.
Singh S, Lathoria K, Umdor SB, Singh J, Suri V, Sen E. | 02/27/2024 |
| The knockdown of lncRNA DLGAP1-AS2 suppresses osteosarcoma progression by inhibiting aerobic glycolysis via the miR-451a/HK2 axis. | The knockdown of lncRNA DLGAP1-AS2 suppresses osteosarcoma progression by inhibiting aerobic glycolysis via the miR-451a/HK2 axis.
Zheng C, Li R, Zheng S, Fang H, Xu M, Zhong L., Free PMC Article | 02/22/2024 |
| PDLIM1 interacts with HK2 to promote gastric cancer progression through enhancing the Warburg effect via Wnt/beta-catenin signaling. | PDLIM1 interacts with HK2 to promote gastric cancer progression through enhancing the Warburg effect via Wnt/β-catenin signaling.
Lei Y, He L, Li Y, Hou J, Zhang H, Li G. | 01/11/2024 |
| [Expression and Prognostic Impact of HK2 in Bone Marrow of Patients with Newly Diagnosed Acute Myeloid Leukemia]. | [Expression and Prognostic Impact of HK2 in Bone Marrow of Patients with Newly Diagnosed Acute Myeloid Leukemia].
Ma P, Shi LH, Tian L, Wang YF, Zhou JW, Mao YN, Liu W, Hou YW, Sun H. | 10/25/2023 |
| LncRNA-SNHG1 promotes paclitaxel resistance of gastric cancer cells through modulating the miR-216b-5p-hexokianse 2 axis. | LncRNA-SNHG1 promotes paclitaxel resistance of gastric cancer cells through modulating the miR-216b-5p-hexokianse 2 axis.
Xu J, Xu Y, Ye G, Qiu J. | 09/28/2023 |
| microRNA-143 interferes the EGFR-stimulated glucose metabolism to re-sensitize 5-FU resistant colon cancer cells via targeting hexokinase 2. | microRNA-143 interferes the EGFR-stimulated glucose metabolism to re-sensitize 5-FU resistant colon cancer cells via targeting hexokinase 2.
Chen W, Chen Y, Hui T. | 09/28/2023 |
| MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients. | MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients.
Catalano G, Zaza A, Banella C, Pelosi E, Castelli G, de Marinis E, Smigliani A, Travaglini S, Ottone T, Divona M, Del Principe MI, Buccisano F, Maurillo L, Ammatuna E, Testa U, Nervi C, Venditti A, Voso MT, Noguera NI. | 08/9/2023 |
| Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2. | Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Zheng Y, Zhan Y, Zhang Y, Zhang Y, Liu Y, Xie Y, Sun Y, Qian J, Ding Y, Ding Y, Fang Y., Free PMC Article | 08/3/2023 |
| Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion. | Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion.
Lin J, Fang W, Xiang Z, Wang Q, Cheng H, Chen S, Fang J, Liu J, Wang Q, Lu Z, Ma L., Free PMC Article | 07/5/2023 |
| Hsa_circ_0000591 drives osteosarcoma glycolysis and progression by sequestering miR-194-5p and elevating HK2 expression. | Hsa_circ_0000591 drives osteosarcoma glycolysis and progression by sequestering miR-194-5p and elevating HK2 expression.
Wang D, Wang Y, Wang H, Yang Y, Li L, Liu Y, Yin X. | 05/5/2023 |
| L1CAM promotes vasculogenic mimicry formation by miR-143-3p-induced expression of hexokinase 2 in glioma. | L1CAM promotes vasculogenic mimicry formation by miR-143-3p-induced expression of hexokinase 2 in glioma.
Huang Y, Zhu C, Liu P, Ouyang F, Luo J, Lu C, Tang B, Yang X., Free PMC Article | 04/15/2023 |
| High-risk pathological subtype associated FAM83A-AS1 promotes malignancy and glycolysis of lung adenocarcinoma via miR-202-3p/HK2 axis. | High‑risk pathological subtype associated FAM83A‑AS1 promotes malignancy and glycolysis of lung adenocarcinoma via miR‑202‑3p/HK2 axis.
Xiong X, Zhang L, Zang B, Xu D, Chen C, Dong G, Xia W, Wu Y., Free PMC Article | 03/27/2023 |
| Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts. | Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts.
Su W, Li J, Jiang L, Lei L, Li H., Free PMC Article | 02/17/2023 |
| Tumor-suppressive miR-323a inhibits pancreatic cancer cell proliferation and glycolysis through targeting HK-2. | Tumor-suppressive miR-323a inhibits pancreatic cancer cell proliferation and glycolysis through targeting HK-2.
Wei Y, Wang M, Liang M, Liu L, Mo S, Zhang H, Chen Y, Li N. | 01/14/2023 |
| SIRT3 Promotes the Development of Esophageal Squamous Cell Carcinoma by Regulating Hexokinase 2 through the AKT Signaling Pathway. | SIRT3 Promotes the Development of Esophageal Squamous Cell Carcinoma by Regulating Hexokinase 2 through the AKT Signaling Pathway.
Yuan ML, Ren LH, Yu XC, Dong JW, Shi RH. | 12/17/2022 |
| PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling. | PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Wu M, Liu W, Huang H, Chen Z, Chen Y, Zhong Y, Jin Z, Liu X, Zou L. | 12/10/2022 |
| A pan-cancer analysis of the role of hexokinase II (HK2) in human tumors. | A pan-cancer analysis of the role of hexokinase II (HK2) in human tumors.
Li R, Mei S, Ding Q, Wang Q, Yu L, Zi F., Free PMC Article | 11/12/2022 |
| High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration. | High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration.
Kim S, Koh J, Song SG, Yim J, Kim M, Keam B, Kim YT, Kim J, Chung DH, Jeon YK., Free PMC Article | 11/5/2022 |
| A potential pathogenic hypoxia-related gene HK2 in necrotizing enterocolitis (NEC) of newborns. | A potential pathogenic hypoxia-related gene HK2 in necrotizing enterocolitis (NEC) of newborns.
Han Y, Liu X, Kang L, Chen D, Li Y, Zhang H, Sun M, Gao H, Gai Z, Li X., Free PMC Article | 11/5/2022 |