| Effect of 12-wk Training in Ovariectomised Rats on PGC-1alpha, NRF-1 and Energy Substrates. | Effect of 12-wk Training in Ovariectomised Rats on PGC-1α, NRF-1 and Energy Substrates.
Pejon TMM, Faria VS, Gobatto CA, Manchado-Gobatto FB, Scariot PPM, Cornachione AS, Beck WR. | 06/25/2022 |
| Effects of NRF-1 and PGC-1alpha cooperation on HIF-1alpha and rat cardiomyocyte apoptosis under hypoxia. | Effects of NRF-1 and PGC-1α cooperation on HIF-1α and rat cardiomyocyte apoptosis under hypoxia.
Niu N, Li H, Du X, Wang C, Li J, Yang J, Liu C, Yang S, Zhu Y, Zhao W. | 06/25/2022 |
| Nrf1 Knock-Down in the Hypothalamic Paraventricular Nucleus Alleviates Hypertension Through Intervention of Superoxide Production-Removal Balance and Mitochondrial Function. | Nrf1 Knock-Down in the Hypothalamic Paraventricular Nucleus Alleviates Hypertension Through Intervention of Superoxide Production-Removal Balance and Mitochondrial Function.
Li Y, Yu XJ, Xiao T, Chi HL, Zhu GQ, Kang YM. | 01/29/2022 |
| Testosterone attenuates pulmonary epithelial inflammation in male rats of COPD model through preventing NRF1-derived NF-kappaB signaling. | Testosterone attenuates pulmonary epithelial inflammation in male rats of COPD model through preventing NRF1-derived NF-κB signaling.
Wang X, Huang L, Jiang S, Cheng K, Wang D, Luo Q, Wu X, Zhu L., Free PMC Article | 01/22/2022 |
| Nuclear respiratory factor 1 protects H9C2 cells against hypoxia-induced apoptosis via the death receptor pathway and mitochondrial pathway. | Nuclear respiratory factor 1 protects H9C2 cells against hypoxia-induced apoptosis via the death receptor pathway and mitochondrial pathway.
Li H, Niu N, Yang J, Dong F, Zhang T, Li S, Zhao W. | 12/25/2021 |
| NRF1-enhanced miR-4458 alleviates cardiac hypertrophy through releasing TTP-inhibited TFAM. | NRF1-enhanced miR-4458 alleviates cardiac hypertrophy through releasing TTP-inhibited TFAM.
Yang M, Zhang J, Jin X, Li C, Zhou G, Feng J. | 12/5/2020 |
| Identification of microRNA3633p as an essential regulator of chondrocyte apoptosis in osteoarthritis by targeting NRF1 through the p53signaling pathway. | Identification of microRNA‑363‑3p as an essential regulator of chondrocyte apoptosis in osteoarthritis by targeting NRF1 through the p53‑signaling pathway.
Zhang M, Wang Z, Li B, Sun F, Chen A, Gong M., Free PMC Article | 10/24/2020 |
| NRF1 regulates testosterone synthesis through transcription regulation of Star. | Transcription regulation of NRF1 on StAR reduces testosterone synthesis in hypoxemic murine.
Wang X, Jin L, Jiang S, Wang D, Lu Y, Zhu L. | 11/23/2019 |
| the present study demonstrated that NRF1 protected against CoCl2induced apoptosis, potentially by strengthening mitochondrial function to resist CoCl2induced damage to H9C2 cells. The results of the present study provide a possible way for the investigation of myocardial diseases. | Effects of nuclear respiratory factor‑1 on apoptosis and mitochondrial dysfunction induced by cobalt chloride in H9C2 cells.
Niu N, Li Z, Zhu M, Sun H, Yang J, Xu S, Zhao W, Song R., Free PMC Article | 05/25/2019 |
| Our findings suggest that NRF-1 regulates the expression of CXCR4 in normal retinal development and in pathologic processes of retinal hypoxia and neovascularization. | Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina.
Chen P, Cai X, Yang Y, Chen Z, Qiu J, Yu N, Tang M, Wang Q, Ge J, Yu K, Zhuang J. | 09/23/2017 |
| Animal physical conditioning increases hyper-acetylation of histones and increased the expression of NRF-1 and MEF2A genes. | Exercise increases hyper-acetylation of histones on the Cis-element of NRF-1 binding to the Mef2a promoter: Implications on type 2 diabetes.
Joseph JS, Ayeleso AO, Mukwevho E. | 06/24/2017 |
| finding suggest that NRF-1 plays a pivotal role on renal cellular fibrosis. | Elucidation of the therapeutic role of mitochondrial biogenesis transducers NRF-1 in the regulation of renal fibrosis.
Hsieh PF, Liu SF, Hung TJ, Hung CY, Liu GZ, Chuang LY, Chen MF, Wang JL, Shi MD, Hsu CH, Shiue YL, Yang YL. | 05/20/2017 |
| in the group that received Nrf1-siRNA, anxiety-related behavior did not show any significant changes compared to the control group. | Complexity of Compensatory Effects in Nrf1 Knockdown: Linking Undeveloped Anxiety-Like Behavior to Prevented Mitochondrial Dysfunction and Oxidative Stress.
Khalifeh S, Oryan S, Khodagholi F, Digaleh H, Shaerzadeh F, Maghsoudi N, Zarrindast MR. | 02/18/2017 |
| Nrf1 is time-dependently expressed and distributed in the distinct cell types after trauma to skeletal muscles in rats. | Nrf1 is time-dependently expressed and distributed in the distinct cell types after trauma to skeletal muscles in rats.
Zhang ST, Zhao R, Ma WX, Fan YY, Guan WZ, Wang J, Ren P, Zhong K, Yu TS, Pi JB, Guan DW. | 11/23/2013 |
| NRF-1 has been identified as a mediator of the expression of nuclear genes encoding mitochondrial proteins. | Contractile activity-induced gene expression in fast- and slow-twitch muscle.
Nguyen LM, Hood DA. | 07/16/2011 |
| Activation of AMPK increases NRF-1 mRNA levels in visual cortex neuron cultures.1 week of monocular deprivation significantly reduces AMPK phosphorylation & down-regulates NRF-1 expression in deprived primary visual cortex. | AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha and nuclear respiratory factor 1 expression in rat visual cortical neurons.
Yu L, Yang SJ. | 03/5/2011 |
| NRF-1 functionally bound to Nos1, but not Nos2 (inducible) and Nos3 (endothelial) gene promoters. | Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c oxidase genes in neurons.
Dhar SS, Liang HL, Wong-Riley MT., Free PMC Article | 01/21/2010 |
| The activity of Nrf1 critically depends on its topology within the ER, and this is modulated by redox stressors, as well as by its glycosylation status. | The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors.
Zhang Y, Lucocq JM, Hayes JD. | 01/21/2010 |
| SDHa flavoprotein transcriptional regulation by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells | Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells.
Piantadosi CA, Suliman HB., Free PMC Article | 01/21/2010 |
| These results of this study strongly indicate that the expression and compartmental redistribution of nuclear respiratory factor 1 protein and mRNA in visual cortical neurons are dynamic processes tightly controlled by neuronal activity. | Activity-dependent transcriptional regulation of nuclear respiratory factor-1 in cultured rat visual cortical neurons.
Yang SJ, Liang HL, Wong-Riley MT. | 01/21/2010 |
| novel redox regulation of NRF-1 phosphorylation and nuclear translocation by phosphatidylinositol 3,4,5-triphosphate kinase/Akt signaling in controlling Tfam induction by an anti-oxidant pro-survival network | Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1.
Piantadosi CA, Suliman HB. | 01/21/2010 |
| oxidative stress stimulates mitochondrial biogenesis in part via nuclear respiratory factor 1 (NRF-1) activation and corresponding to recovery events after LPS-induced liver damage. | Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1.
Suliman HB, Carraway MS, Welty-Wolf KE, Whorton AR, Piantadosi CA. | 01/21/2010 |