| MR1 antigen presentation to MAIT cells and other MR1-restricted T cells. | MR1 antigen presentation to MAIT cells and other MR1-restricted T cells.
McWilliam HEG, Villadangos JA., Free PMC Article | 03/5/2024 |
| The MR1/MAIT cell axis in CNS diseases. | The MR1/MAIT cell axis in CNS diseases.
Shrinivasan R, Wyatt-Johnson SK, Brutkiewicz RR., | 01/28/2024 |
| Characterization of the TCRbeta repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients. | Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients.
Jirouš Drulak M, Grgić Z, Plužarić V, Šola M, Opačak-Bernardi T, Viljetić B, Glavaš K, Tolušić-Levak M, Periša V, Mihalj M, Štefanić M, Tokić S., Free PMC Article | 12/1/2023 |
| Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis. | Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis.
Wyatt-Johnson SK, Kersey HN, Codocedo JF, Newell KL, Landreth GE, Lamb BT, Oblak AL, Brutkiewicz RR., Free PMC Article | 03/29/2023 |
| Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation. | Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation.
Ashley CL, McSharry BP, McWilliam HEG, Stanton RJ, Fielding CA, Mathias RA, Fairlie DP, McCluskey J, Villadangos JA, Rossjohn J, Abendroth A, Slobedman B., Free PMC Article | 03/1/2023 |
| Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing. | Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing.
du Halgouet A, Darbois A, Alkobtawi M, Mestdagh M, Alphonse A, Premel V, Yvorra T, Colombeau L, Rodriguez R, Zaiss D, El Morr Y, Bugaut H, Legoux F, Perrin L, Aractingi S, Golub R, Lantz O, Salou M., Free PMC Article | 02/9/2023 |
| A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells. | A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.
Lim HJ, Wubben JM, Garcia CP, Cruz-Gomez S, Deng J, Mak JYW, Hachani A, Anderson RJ, Painter GF, Goyette J, Amarasinghe SL, Ritchie ME, Roquilly A, Fairlie DP, Gaus K, Rossjohn J, Villadangos JA, McWilliam HEG., Free PMC Article | 10/1/2022 |
| MR1 encompasses at least six allele groups with coding region alterations. | MR1 encompasses at least six allele groups with coding region alterations.
Rozemuller E, Eckle SBG, McLaughlin I, Penning M, Mulder W, de Bruin H, van Wageningen S. | 05/14/2022 |
| The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation. | The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation.
Kulicke CA, De Zan E, Hein Z, Gonzalez-Lopez C, Ghanwat S, Veerapen N, Besra GS, Klenerman P, Christianson JC, Springer S, Nijman SM, Cerundolo V, Salio M., Free PMC Article | 05/14/2022 |
| Recognition of the antigen-presenting molecule MR1 by a Vdelta3(+) gammadelta T cell receptor. | Recognition of the antigen-presenting molecule MR1 by a Vδ3(+) γδ T cell receptor.
Rice MT, von Borstel A, Chevour P, Awad W, Howson LJ, Littler DR, Gherardin NA, Le Nours J, Giles EM, Berry R, Godfrey DI, Davey MS, Rossjohn J, Gully BS., Free PMC Article | 01/22/2022 |
| Rab6 regulates recycling and retrograde trafficking of MR1 molecules. | Rab6 regulates recycling and retrograde trafficking of MR1 molecules.
Huber ME, Kurapova R, Heisler CM, Karamooz E, Tafesse FG, Harriff MJ., Free PMC Article | 03/28/2021 |
| Virus-Mediated Suppression of the Antigen Presentation Molecule MR1. | Virus-Mediated Suppression of the Antigen Presentation Molecule MR1.
McSharry BP, Samer C, McWilliam HEG, Ashley CL, Yee MB, Steain M, Liu L, Fairlie DP, Kinchington PR, McCluskey J, Abendroth A, Villadangos JA, Rossjohn J, Slobedman B., Free PMC Article | 03/27/2021 |
| Opsonization-Enhanced Antigen Presentation by MR1 Activates Rapid Polyfunctional MAIT Cell Responses Acting as an Effector Arm of Humoral Antibacterial Immunity. | Opsonization-Enhanced Antigen Presentation by MR1 Activates Rapid Polyfunctional MAIT Cell Responses Acting as an Effector Arm of Humoral Antibacterial Immunity.
Boulouis C, Gorin JB, Dias J, Bergman P, Leeansyah E, Sandberg JK., Free PMC Article | 03/13/2021 |
| T cell receptor diversity, specificity and promiscuity of functionally heterogeneous human MR1-restricted T cells. | T cell receptor diversity, specificity and promiscuity of functionally heterogeneous human MR1-restricted T cells.
Lepore M, Lewinsohn DA, Lewinsohn DM., Free PMC Article | 03/6/2021 |
| Antigen specificities and functional properties of MR1-restricted T cells. | Antigen specificities and functional properties of MR1-restricted T cells.
De Libero G, Chancellor A, Mori L. | 03/6/2021 |
| Atypical TRAV1-2(-) T cell receptor recognition of the antigen-presenting molecule MR1. | Atypical TRAV1-2(-) T cell receptor recognition of the antigen-presenting molecule MR1.
Awad W, Meermeier EW, Sandoval-Romero ML, Le Nours J, Worley AH, Null MD, Liu L, McCluskey J, Fairlie DP, Lewinsohn DM, Rossjohn J., Free PMC Article | 02/27/2021 |
| MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1. | MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1.
Yan J, Allen S, McDonald E, Das I, Mak JYW, Liu L, Fairlie DP, Meehan BS, Chen Z, Corbett AJ, Varelias A, Smyth MJ, Teng MWL. | 02/13/2021 |
| Alternative splicing of MR1 regulates antigen presentation to MAIT cells. | Alternative splicing of MR1 regulates antigen presentation to MAIT cells.
Narayanan GA, Nellore A, Tran J, Worley AH, Meermeier EW, Karamooz E, Huber ME, Kurapova R, Tafesse FG, Harriff MJ, Lewinsohn DM., Free PMC Article | 12/19/2020 |
| Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens. | Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens.
McWilliam HEG, Mak JYW, Awad W, Zorkau M, Cruz-Gomez S, Lim HJ, Yan Y, Wormald S, Dagley LF, Eckle SBG, Corbett AJ, Liu H, Li S, Reddiex SJJ, Mintern JD, Liu L, McCluskey J, Rossjohn J, Fairlie DP, Villadangos JA., Free PMC Article | 11/28/2020 |
| BCL11B regulates MICA/B-mediated immune response by acting as a competitive endogenous RNA. | BCL11B regulates MICA/B-mediated immune response by acting as a competitive endogenous RNA.
Qian M, Geng J, Luo K, Huang Z, Zhang Q, Zhang JA, Ji L, Wu J. | 11/28/2020 |
| MR1 recycling and blockade of endosomal trafficking reveal distinguishable antigen presentation pathways between Mycobacterium tuberculosis infection and exogenously delivered antigens. | MR1 recycling and blockade of endosomal trafficking reveal distinguishable antigen presentation pathways between Mycobacterium tuberculosis infection and exogenously delivered antigens.
Karamooz E, Harriff MJ, Narayanan GA, Worley A, Lewinsohn DM., Free PMC Article | 10/3/2020 |
| The BCG-induced IFN-gamma expression by MAIT cells in vitro was mediated by the innate cytokines IL-12 and IL-18 more than MR1-induced TCR signaling, suggesting TCR-independent activation. | MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria.
Suliman S, Murphy M, Musvosvi M, Gela A, Meermeier EW, Geldenhuys H, Hopley C, Toefy A, Bilek N, Veldsman A, Hanekom WA, Johnson JL, Boom WH, Obermoser G, Huang H, Hatherill M, Lewinsohn DM, Nemes E, Scriba TJ., Free PMC Article | 05/30/2020 |
| this study reports MR1 as a ligand for human gamma delta T cells and redefines the parameters for TCR recognition. | A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Le Nours J, Gherardin NA, Ramarathinam SH, Awad W, Wiede F, Gully BS, Khandokar Y, Praveena T, Wubben JM, Sandow JJ, Webb AI, von Borstel A, Rice MT, Redmond SJ, Seneviratna R, Sandoval-Romero ML, Li S, Souter MNT, Eckle SBG, Corbett AJ, Reid HH, Liu L, Fairlie DP, Giles EM, Westall GP, Tothill RW, Davey MS, Berry R, Tiganis T, McCluskey J, Pellicci DG, Purcell AW, Uldrich AP, Godfrey DI, Rossjohn J. | 04/4/2020 |
| Role of CD1d- and MR1-Restricted T Cells in Asthma. | Role of CD1d- and MR1-Restricted T Cells in Asthma.
Iwamura C, Nakayama T., Free PMC Article | 09/21/2019 |
| Human mucosal-associated invariant T cells possess capacity for B cell help via MR1-mediated immunoglobulins production. | Human mucosal-associated invariant T (MAIT) cells possess capacity for B cell help.
Bennett MS, Trivedi S, Iyer AS, Hale JS, Leung DT., Free PMC Article | 11/11/2017 |