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    HMGB1 high mobility group box 1 [ Homo sapiens (human) ]

    Gene ID: 3146, updated on 8-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The Association of HMGB1 and RAGE Gene Polymorphisms with IgA Vasculitis.

    The Association of HMGB1 and RAGE Gene Polymorphisms with IgA Vasculitis.
    Batnozic Varga M, Held M, Wagner J, Arvaj N, Sestan M, Sapina M, Kifer N, Grguric D, Crkvenac Gornik K, Gagro A, Frkovic M, Jelusic M.

    07/5/2024
    CircUBE2D2 regulates HMGB1 through miR-885-5p to promote ovarian cancer malignancy.

    CircUBE2D2 regulates HMGB1 through miR-885-5p to promote ovarian cancer malignancy.
    Yan R, Zeng S, Gao F, Li L, Xiao X., Free PMC Article

    06/20/2024
    High mobility group box 1 mediates inflammatory responses in malignant peritoneal mesothelioma.

    High mobility group box 1 mediates inflammatory responses in malignant peritoneal mesothelioma.
    Wang L, Wang X, Sun N, Liu W.

    06/18/2024
    Tumor cells express and maintain HMGB1 in the reduced isoform to enhance CXCR4-mediated migration.

    Tumor cells express and maintain HMGB1 in the reduced isoform to enhance CXCR4-mediated migration.
    Pirani E, Paparoditis P, Pecoraro M, Danelon G, Thelen M, Cecchinato V, Uguccioni M., Free PMC Article

    06/5/2024
    Targeting BMAL1 reverses drug resistance of acute myeloid leukemia cells and promotes ferroptosis through HMGB1-GPX4 signaling pathway.

    Targeting BMAL1 reverses drug resistance of acute myeloid leukemia cells and promotes ferroptosis through HMGB1-GPX4 signaling pathway.
    Zheng H, Wu T, Lin Z, Wang D, Zhang J, Zeng T, Liu L, Shen J, Zhao M, Li JD, Yang M., Free PMC Article

    05/9/2024
    Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV).

    Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV).
    Held M, Kozmar A, Sestan M, Turudic D, Kifer N, Srsen S, Gagro A, Frkovic M, Jelusic M., Free PMC Article

    05/7/2024
    HMGB1 prefers to interact with structural RNAs and regulates rRNA methylation modification and translation in HeLa cells.

    HMGB1 prefers to interact with structural RNAs and regulates rRNA methylation modification and translation in HeLa cells.
    Liao M, Cao J, Chen W, Wang M, Jin Z, Ye J, Ren Y, Wei Y, Xue Y, Chen D, Zhang Y, Chen S., Free PMC Article

    04/18/2024
    Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.

    Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
    Wang Y, Wang S, Wang Y, Wang C, Tang Y, Zhang C, Hou S, Yu D, Lin N.

    04/12/2024
    The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer.

    The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer.
    Salamini-Montemurri M, Vizoso-Vázquez Á, Barreiro-Alonso A, Lorenzo-Catoira L, Rodríguez-Belmonte E, Cerdán ME, Lamas-Maceiras M., Free PMC Article

    04/2/2024
    High Mobility Group Box 1 Gene Polymorphism and Serum High Mobility Group Box 1, Interleukin 1 Beta, and Alpha-Klotho Crosstalk in Severe COVID-19 Patients.

    High Mobility Group Box 1 Gene Polymorphism and Serum High Mobility Group Box 1, Interleukin 1 Beta, and Alpha-Klotho Crosstalk in Severe COVID-19 Patients.
    Houssen M, El-Mahdy R, Samra NE, Tera Y, Nayera Mostafa K, El-Desoky MM, Hisham FA, Hewidy AA, Elmorsey RA, Samaha H, Mahmoud R, Abdelhafez MS.

    03/29/2024
    High mobility group box-1: A therapeutic target for analgesia and associated symptoms in chronic pain.

    High mobility group box-1: A therapeutic target for analgesia and associated symptoms in chronic pain.
    Morioka N, Nakamura Y, Hisaoka-Nakashima K, Nakata Y.

    03/28/2024
    Altered release of thrombomodulin and HMGB1 in the placenta complicated with preeclampsia.

    Altered release of thrombomodulin and HMGB1 in the placenta complicated with preeclampsia.
    Oda H, Nagamatsu T, Iriyama T, Osuga Y.

    03/19/2024
    High-mobility group box 1 increases platelet surface P2Y12 and platelet activation in sickle cell disease.

    High-mobility group box 1 increases platelet surface P2Y12 and platelet activation in sickle cell disease.
    Nolfi-Donegan D, Annarapu GK, St Croix C, Calderon M, Hillery CA, Shiva S., Free PMC Article

    03/13/2024
    HMGB1 regulates Th17 cell differentiation and function in patients with psoriasis.

    HMGB1 regulates Th17 cell differentiation and function in patients with psoriasis.
    Zhu X, Dou Y, Lin Y, Chu G, Wang J, Ma L., Free PMC Article

    02/29/2024
    HMGB1 promotes mitochondrial transfer between hepatocellular carcinoma cells through RHOT1 and RAC1 under hypoxia.

    HMGB1 promotes mitochondrial transfer between hepatocellular carcinoma cells through RHOT1 and RAC1 under hypoxia.
    Jing M, Xiong X, Mao X, Song Q, Zhang L, Ouyang Y, Pang Y, Fu Y, Yan W., Free PMC Article

    02/23/2024
    GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma.

    GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma.
    Tang H, Guo Y, Gan S, Chen Z, Dong M, Lin L, Chen H, Ji X, Xian M, Shi X, Tao A, Lv Y, Yao L, Chen R, Li S, Li J.

    02/21/2024
    Musashi-2 potentiates colorectal cancer immune infiltration by regulating the post-translational modifications of HMGB1 to promote DCs maturation and migration.

    Musashi-2 potentiates colorectal cancer immune infiltration by regulating the post-translational modifications of HMGB1 to promote DCs maturation and migration.
    Meng X, Na R, Peng X, Li H, Ouyang W, Zhou W, You X, Li Y, Pu X, Zhang K, Xia J, Wang J, Tang H, Zhuang G, Peng Z., Free PMC Article

    02/20/2024
    HMGB1 in exosomes derived from gastric cancer cells induces M2-like macrophage polarization by inhibiting the NF-kappaB signaling pathway.

    HMGB1 in exosomes derived from gastric cancer cells induces M2-like macrophage polarization by inhibiting the NF-κB signaling pathway.
    Liu K, Wang H, Zhou J, Zhu S, Ma M, Xiao H, Ding Y.

    02/16/2024
    Blockade of HMGB1 Reduces Inflammation and Pruritus in Atopic Dermatitis by Inhibiting Skin Fibroblasts Activation.

    Blockade of HMGB1 Reduces Inflammation and Pruritus in Atopic Dermatitis by Inhibiting Skin Fibroblasts Activation.
    Zhou L, Yuan X, Hu Y, Zhu S, Li J, Wang C, Jing M, Liu L, Xu Z, Zhao Z, Zhao J., Free PMC Article

    02/12/2024
    LINC01094 promotes human nasal epithelial cell epithelial-to-mesenchymal transition and pyroptosis via upregulating HMGB1.

    LINC01094 promotes human nasal epithelial cell epithelial-to-mesenchymal transition and pyroptosis via upregulating HMGB1.
    Liu Z, Fu Y, Huang W, Li C, Wei X, Zhan J, Zheng J.

    02/8/2024
    ASSOCIATION BETWEEN HIGH MOBILITY GROUP BOX 1 PROTEIN GENE (rs41369348) POLYMORPHISM AND IMMUNOGLOBULIN A VASCULITIS IN CHILDREN.

    ASSOCIATION BETWEEN HIGH MOBILITY GROUP BOX 1 PROTEIN GENE (rs41369348) POLYMORPHISM AND IMMUNOGLOBULIN A VASCULITIS IN CHILDREN.
    Batnožić Varga M, Šestan M, Wagner J, Crkvenac Gornik K, Kifer N, Frković M, Stefinovec L, Vučemilović Jurić V, Grgurić D, Pušeljić S, Jelušić M., Free PMC Article

    02/6/2024
    High mobility group box 1 knockdown inhibits EV71 replication and attenuates cell pyroptosis through TLR4/NF-kappaB/NLRP3 axis.

    High mobility group box 1 knockdown inhibits EV71 replication and attenuates cell pyroptosis through TLR4/NF-κB/NLRP3 axis.
    Zhang Y, Li J, Deng H, Wan H, Xu P, Wang J, Liu R, Tang T.

    02/6/2024
    The Interaction of HMGB1 with the Proinflammatory TREM-1 Receptor Generates Cytotoxic Lymphocytes Active against HLA-Negative Tumor Cells.

    The Interaction of HMGB1 with the Proinflammatory TREM-1 Receptor Generates Cytotoxic Lymphocytes Active against HLA-Negative Tumor Cells.
    Yurkina DM, Romanova EA, Feoktistov AV, Soshnikova NV, Tvorogova AV, Yashin DV, Sashchenko LP., Free PMC Article

    02/6/2024
    Could serum HMGB1 levels be a predictor associated with psoriatic arthritis?

    Could serum HMGB1 levels be a predictor associated with psoriatic arthritis?
    Yildirim D, Baykul M, Edek YC, Gulengul M, Alp GT, Eroglu FS, Adisen E, Kucuk H, Erden A, Goker B, Nas K, Ozturk MA.

    01/29/2024
    Mutual promotion of co-condensation of KRAS G-quadruplex and a well-folded protein HMGB1.

    Mutual promotion of co-condensation of KRAS G-quadruplex and a well-folded protein HMGB1.
    Wang Y, Cao K, Zong M, Yuan S, Zhang N, Liu Y., Free PMC Article

    01/26/2024
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