HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1. | HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1. Fan J, Gillespie KP, Mesaros C, Blair IA., Free PMC Article | 10/8/2024 |
LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis. | LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis. Wang Y, Yang Y, Zhang T, Jia S, Ma X, Zhang M, Wang L, Ma A. | 07/26/2024 |
The transcription factor HMGB2 indirectly regulates APRIL expression and Gd-IgA1 production in patients with IgA nephropathy. | The transcription factor HMGB2 indirectly regulates APRIL expression and Gd-IgA1 production in patients with IgA nephropathy. Tian H, Zhai Y, Sun S, Zhang W, Zhao Z., Free PMC Article | 04/22/2024 |
The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer. | The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer. Salamini-Montemurri M, Vizoso-Vázquez Á, Barreiro-Alonso A, Lorenzo-Catoira L, Rodríguez-Belmonte E, Cerdán ME, Lamas-Maceiras M., Free PMC Article | 04/2/2024 |
Correlation of serum HMGB1 and HMGB2 levels with clinical symptoms in allergic rhinitis children. | Correlation of serum HMGB1 and HMGB2 levels with clinical symptoms in allergic rhinitis children. Xing X, Wang H., Free PMC Article | 09/23/2023 |
Clinical and Experimental Study of High Mobility Group Box-2 and Valvular Calcification in Elderly Patients with Degenerative Heart Valve Disease. | Clinical and Experimental Study of High Mobility Group Box-2 and Valvular Calcification in Elderly Patients with Degenerative Heart Valve Disease. Huang H, Sun Q, Huang Y, Wang H, Ju L, Peng M, Wu J, Chen L, Gong Y. | 07/21/2023 |
Structure and Functions of HMGB2 Protein. | Structure and Functions of HMGB2 Protein. Starkova T, Polyanichko A, Tomilin AN, Chikhirzhina E., Free PMC Article | 05/22/2023 |
Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes. | Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes. Zhang H, Xiang X, Zhou B, Chen J, Sun Y, Zhang S, Li A, Li J. | 05/15/2023 |
Long non-coding RNA NR2F2-AS1 regulates human osteosarcoma growth and metastasis through miR-425-5p-mediated HMGB2. | Long non-coding RNA NR2F2-AS1 regulates human osteosarcoma growth and metastasis through miR-425-5p-mediated HMGB2. Ye J, He H, Chen S, Ren Y, Guo W, Jin Z. | 12/3/2022 |
[microRNA let-7g-3p regulates proliferation, migration, invasion and apoptosis of bladder cancer cells by targeting HMGB2]. | [microRNA let-7g-3p regulates proliferation, migration, invasion and apoptosis of bladder cancer cells by targeting HMGB2]. Zou Z, Cheng Q, Li Z, Gao W, Sun W, Liu B, Guo Y, Liu J., Free PMC Article | 10/15/2022 |
MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway. | MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway. Chen F, Li W, Zhang D, Fu Y, Yuan W, Luo G, Liu F, Luo J., Free PMC Article | 06/25/2022 |
Circular RNA circ_UBAP2 facilitates the progression of osteosarcoma by regulating microRNA miR-637/high-mobility group box (HMGB) 2 axis. | Circular RNA circ_UBAP2 facilitates the progression of osteosarcoma by regulating microRNA miR-637/high-mobility group box (HMGB) 2 axis. Ma W, Zhao X, Gao Y, Yao X, Zhang J, Xu Q., Free PMC Article | 03/26/2022 |
LINC00184 plays an oncogenic role in non-small cell lung cancer via regulation of the miR-524-5p/HMGB2 axis. | LINC00184 plays an oncogenic role in non-small cell lung cancer via regulation of the miR-524-5p/HMGB2 axis. Wang W, Li L, Zhao L., Free PMC Article | 03/19/2022 |
Centromere protein U (CENPU) promotes gastric cancer cell proliferation and glycolysis by regulating high mobility group box 2 (HMGB2). | Centromere protein U (CENPU) promotes gastric cancer cell proliferation and glycolysis by regulating high mobility group box 2 (HMGB2). Deng T, Jiang X, He Z, Cai M, Chen C, Xu Z., Free PMC Article | 02/19/2022 |
High-mobility group box 2 reflects exacerbated disease characteristics and poor prognosis in non-small cell lung cancer patients. | High-mobility group box 2 reflects exacerbated disease characteristics and poor prognosis in non-small cell lung cancer patients. Lou N, Zhu T, Qin D, Tian J, Liu J. | 01/29/2022 |
Interactions of HMGB Proteins with the Genome and the Impact on Disease. | Interactions of HMGB Proteins with the Genome and the Impact on Disease. Voong CK, Goodrich JA, Kugel JF., Free PMC Article | 01/22/2022 |
LncRNA SNHG1 promotes the development of oral cavity cancer via regulating the miR-421/HMGB2 axis. | LncRNA SNHG1 promotes the development of oral cavity cancer via regulating the miR-421/HMGB2 axis. Liu J, Zhao C, Yang S, Dong C. | 12/18/2021 |
Nonhistone Proteins HMGB1 and HMGB2 Differentially Modulate the Response of Human Embryonic Stem Cells and the Progenitor Cells to the Anticancer Drug Etoposide. | Nonhistone Proteins HMGB1 and HMGB2 Differentially Modulate the Response of Human Embryonic Stem Cells and the Progenitor Cells to the Anticancer Drug Etoposide. Bagherpoor AJ, Kučírek M, Fedr R, Sani SA, Štros M., Free PMC Article | 06/26/2021 |
Knockdown of HMGB2 inhibits proliferation and invasion of renal tumor cells via the p-38MAPK pathway. | Knockdown of HMGB2 inhibits proliferation and invasion of renal tumor cells via the p-38MAPK pathway. He ZH, Guo F, Hu XX, Luo ZY, Yi JW. | 04/24/2021 |
MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency. | MicroRNA-127-5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency. Zhang X, Dang Y, Liu R, Zhao S, Ma J, Qin Y. | 03/20/2021 |
Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer. | Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer. Fang J, Ge X, Xu W, Xie J, Qin Z, Shi L, Yin W, Bian M, Wang H. | 02/6/2021 |
Elevated hsa-miR-590-3p expression down-regulates HMGB2 expression and contributes to the severity of IgA nephropathy. | Elevated hsa-miR-590-3p expression down-regulates HMGB2 expression and contributes to the severity of IgA nephropathy. Zhai Y, Qi Y, Long X, Dou Y, Liu D, Cheng G, Xiao J, Liu Z, Zhao Z., Free PMC Article | 09/19/2020 |
High-mobility group box 2 promoted proliferation of cervical cancer cells by activating AKT signaling pathway. | High-mobility group box 2 promoted proliferation of cervical cancer cells by activating AKT signaling pathway. Zhang P, Lu Y, Gao S. | 09/19/2020 |
lncRNA HOXA11-AS was overexpressed in glioma and overexpression was correlated with advanced stages of glioma and poor prognosis. Downregulating HOXA11-AS expression significantly suppressed proliferation, migration and invasion of glioma cells and increased their apoptosis. HOXA11-AS exerted its oncogenic effects by binding to miR-130a-5p, thereby neutralizing the suppressive effect of miR-130a-5p on HMGB2. | The lncRNA HOXA11-AS promotes glioma cell growth and metastasis by targeting miR-130a-5p/HMGB2. Xu CH, Xiao LM, Liu Y, Chen LK, Zheng SY, Zeng EM, Li DH. | 06/20/2020 |
impact of HMGB1/2 KD on telomerase transcriptional regulation observed in neuroectodermal cells is partially masked in hESCs by their pluripotent state. Our findings on differential roles of HMGB1 and HMGB2 proteins in regulation of telomerase activity may suggest another possible outcome of HMGB1 targeting in cells, which is currently a promising approach aiming at increasing the anticancer activity of cytotoxic agents | HMGB2 is a negative regulator of telomerase activity in human embryonic stem and progenitor cells. Kučírek M, Bagherpoor AJ, Jaroš J, Hampl A, Štros M. | 06/13/2020 |