| Exosomal HMGB3 released by glioma cells confers the activation of NLRP3 inflammasome and pyroptosis in tumor-associated macrophages. | Exosomal HMGB3 released by glioma cells confers the activation of NLRP3 inflammasome and pyroptosis in tumor-associated macrophages.
Hu P, Yan T, Lv S, Ye M, Wu M, Fang H, Xiao B. | 07/1/2024 |
| HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway. | HMGB3 promotes the malignant phenotypes and stemness of epithelial ovarian cancer through the MAPK/ERK signaling pathway.
Ma H, Qi G, Han F, Gai P, Peng J, Kong B., Free PMC Article | 06/23/2023 |
| Circ-IGF1R Affects the Progression of Colorectal Cancer by Activating the miR-362-5p/HMGB3-Mediated Wnt/beta-Catenin Signal Pathway. | Circ-IGF1R Affects the Progression of Colorectal Cancer by Activating the miR-362-5p/HMGB3-Mediated Wnt/β-Catenin Signal Pathway.
Gao S, Zhang X, Bai W, Wang J, Jiang B. | 05/30/2023 |
| SOX9 and HMGB3 co-operatively transactivate NANOG and promote prostate cancer progression. | SOX9 and HMGB3 co-operatively transactivate NANOG and promote prostate cancer progression.
Xu Y, Xu M, Li X, Weng X, Su Z, Zhang M, Tan J, Zeng H, Li X, Nie L, Gong J, Chen N, Chen X, Zhou Q. | 02/28/2023 |
| Long Noncoding RNA Brain Cytoplasmic RNA 1 Induces Cisplatin-Resistance of Cervical Cancer Cells by Sponging MicroRNA-330-5p and Upregulating High-Mobility Group Box 3. | Long Noncoding RNA Brain Cytoplasmic RNA 1 Induces Cisplatin-Resistance of Cervical Cancer Cells by Sponging MicroRNA-330-5p and Upregulating High-Mobility Group Box 3.
Sun D, Cao R, Han L, Yu X, Wang H, Wang X, Chen X. | 10/15/2022 |
| HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer. | HMGB3 promotes PARP inhibitor resistance through interacting with PARP1 in ovarian cancer.
Ma H, Qi G, Han F, Lu W, Peng J, Li R, Yan S, Yuan C, Kong B., Free PMC Article | 04/23/2022 |
| LINC00319 promotes cancer stem cell-like properties in laryngeal squamous cell carcinoma via E2F1-mediated upregulation of HMGB3. | LINC00319 promotes cancer stem cell-like properties in laryngeal squamous cell carcinoma via E2F1-mediated upregulation of HMGB3.
Yuan L, Tian X, Zhang Y, Huang X, Li Q, Li W, Li S., Free PMC Article | 03/26/2022 |
| miR-142-3p simultaneously targets HMGA1, HMGA2, HMGB1, and HMGB3 and inhibits tumorigenic properties and in-vivo metastatic potential of human cervical cancer cells. | miR-142-3p simultaneously targets HMGA1, HMGA2, HMGB1, and HMGB3 and inhibits tumorigenic properties and in-vivo metastatic potential of human cervical cancer cells.
Sharma P, Yadav P, Jain RP, Bera AK, Karunagaran D. | 02/19/2022 |
| LINC00857 promotes colorectal cancer progression by sponging miR-150-5p and upregulating HMGB3 (high mobility group box 3) expression. | LINC00857 promotes colorectal cancer progression by sponging miR-150-5p and upregulating HMGB3 (high mobility group box 3) expression.
Zhou D, He S, Zhang D, Lv Z, Yu J, Li Q, Li M, Guo W, Qi F., Free PMC Article | 02/19/2022 |
| HDAC3 increases HMGB3 expression to facilitate the immune escape of breast cancer cells via down-regulating microRNA-130a-3p. | HDAC3 increases HMGB3 expression to facilitate the immune escape of breast cancer cells via down-regulating microRNA-130a-3p.
Chen Z, Pei L, Zhang D, Xu F, Zhou E, Chen X. | 10/2/2021 |
| High mobility group box 3 promotes cervical cancer proliferation by regulating Wnt/beta-catenin pathway. | High mobility group box 3 promotes cervical cancer proliferation by regulating Wnt/β-catenin pathway.
Zhuang S, Yu X, Lu M, Li Y, Ding N, Ding Y., Free PMC Article | 09/4/2021 |
| MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells. | MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells.
Gu M, Jiang Z, Li H, Peng J, Chen X, Tang M. | 09/4/2021 |
| CircRNA_102179 promotes the proliferation, migration and invasion in non-small cell lung cancer cells by regulating miR-330-5p/HMGB3 axis. | CircRNA_102179 promotes the proliferation, migration and invasion in non-small cell lung cancer cells by regulating miR-330-5p/HMGB3 axis.
Zhou ZF, Wei Z, Yao JC, Liu SY, Wang F, Wang Z, Chen XF, Lin H, Ye Y, Zheng QF. | 08/28/2021 |
| Long Noncoding RNA SOX2-OT Knockdown Inhibits Proliferation and Metastasis of Prostate Cancer Cells Through Modulating the miR-452-5p/HMGB3 Axis and Inactivating Wnt/beta-Catenin Pathway. | Long Noncoding RNA SOX2-OT Knockdown Inhibits Proliferation and Metastasis of Prostate Cancer Cells Through Modulating the miR-452-5p/HMGB3 Axis and Inactivating Wnt/β-Catenin Pathway.
Song X, Wang H, Wu J, Sun Y. | 07/17/2021 |
| The role of high mobility group protein B3 (HMGB3) in tumor proliferation and drug resistance. | The role of high mobility group protein B3 (HMGB3) in tumor proliferation and drug resistance.
Wen B, Wei YT, Zhao K. | 07/17/2021 |
| High-mobility group box 3 (HMGB3) silencing inhibits non-small cell lung cancer development through regulating Wnt/beta-catenin pathway. | High-mobility group box 3 (HMGB3) silencing inhibits non-small cell lung cancer development through regulating Wnt/β-catenin pathway.
Li Y, Ma Y, Zhang T, Feng C, Liu Y. | 06/26/2021 |
| LncRNA PITPNA-AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA. | LncRNA PITPNA-AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA.
Ren P, Xing L, Hong X, Chang L, Zhang H., Free PMC Article | 05/22/2021 |
| Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer. | Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.
Fang J, Ge X, Xu W, Xie J, Qin Z, Shi L, Yin W, Bian M, Wang H. | 02/6/2021 |
| Circ-0001801 contributes to cell proliferation, migration, invasion and epithelial to mesenchymal transition (EMT) in glioblastoma by regulating miR-628-5p/HMGB3 axis. | Circ-0001801 contributes to cell proliferation, migration, invasion and epithelial to mesenchymal transition (EMT) in glioblastoma by regulating miR-628-5p/HMGB3 axis.
Chen WL, Jiang L, Wang JS, Liao CX. | 12/19/2020 |
| HMGB3 small interfere RNA suppresses mammosphere formation of MDA-MB-231 cells by down-regulating expression of HIF1alpha. | HMGB3 small interfere RNA suppresses mammosphere formation of MDA-MB-231 cells by down-regulating expression of HIF1α.
Gu J, Xu T, Zhang CM, Chen HY, Huang QH, Zhang Q. | 12/19/2020 |
| LncRNA SNHG5 promotes nasopharyngeal carcinoma progression by regulating miR-1179/HMGB3 axis. | LncRNA SNHG5 promotes nasopharyngeal carcinoma progression by regulating miR-1179/HMGB3 axis.
Liu D, Wang Y, Zhao Y, Gu X., Free PMC Article | 10/24/2020 |
| High HMGB3 expression is associated with Chemo-resistance in Ovarian Cancer. | Targeting the High-Mobility Group Box 3 Protein Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin.
Mukherjee A, Huynh V, Gaines K, Reh WA, Vasquez KM., Free PMC Article | 04/11/2020 |
| HOTTIP was upregulated and miR-615-3p was downregulated in non-small cell lung cancer (NSCLC) tissues and cells. Hypoxia induced glycolysis, increased HOTTIP and HMGB3 mRNA levels and repressed miR-615-3p expression in NSCLC cells. HOTTIP deficiency or miR-615-3p expression restoration repressed hypoxia-induced glycolysis. HOTTIP acted as a molecular sponge for miR-615-3p and HMGB3 was a direct target of miR-615-3p. | Long non-coding RNA HOTTIP promotes hypoxia-induced glycolysis through targeting miR-615-3p/HMGB3 axis in non-small cell lung cancer cells.
Shi J, Wang H, Feng W, Huang S, An J, Qiu Y, Wu K. | 03/7/2020 |
| HMGB3 might be of very great significance to the pathogenesis of FGR and might play the role by leading the dysfunction of placental villous trophoblast cells and through the interaction with some other proteins | Down-regulated expressed protein HMGB3 inhibits proliferation and migration, promotes apoptosis in the placentas of fetal growth restriction.
Lv Y, Lv M, Ji X, Xue L, Rui C, Yin L, Ding H, Miao Z. | 08/31/2019 |
| HMGB3 has higher expression in non-small cell lung cancer tissues.HMGB3 is the target gene of miR-758. | Overexpression of miR-758 inhibited proliferation, migration, invasion, and promoted apoptosis of non-small cell lung cancer cells by negatively regulating HMGB.
Zhou GH, Lu YY, Xie JL, Gao ZK, Wu XB, Yao WS, Gu WG., Free PMC Article | 08/24/2019 |