| Coupled scRNA-seq and Bulk-seq reveal the role of HMMR in hepatocellular carcinoma. | Coupled scRNA-seq and Bulk-seq reveal the role of HMMR in hepatocellular carcinoma.
Su Z, He Y, You L, Zhang G, Chen J, Liu Z., Free PMC Article | 05/2/2024 |
| Targeting hyaluronan-mediated motility receptor (HMMR) enhances response to androgen receptor signalling inhibitors in prostate cancer. | Targeting hyaluronan-mediated motility receptor (HMMR) enhances response to androgen receptor signalling inhibitors in prostate cancer.
Hinneh JA, Gillis JL, Mah CY, Irani S, Shrestha RK, Ryan NK, Atsushi E, Nassar ZD, Lynn DJ, Selth LA, Kato M, Centenera MM, Butler LM., Free PMC Article | 11/3/2023 |
| RHAMM marks proliferative subpopulation of human colorectal cancer stem cells. | RHAMM marks proliferative subpopulation of human colorectal cancer stem cells.
Nakano M, Taguchi R, Kikushige Y, Isobe T, Miyawaki K, Mizuno S, Tsuruta N, Hanamura F, Yamaguchi K, Yamauchi T, Ariyama H, Kusaba H, Nakamura M, Maeda T, Kuo CJ, Baba E, Akashi K., Free PMC Article | 07/12/2023 |
| Receptor for hyaluronan-mediated motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients. | Receptor for hyaluronan-mediated motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients.
Tarullo SE, He Y, Daughters C, Knutson TP, Henzler CM, Price MA, Shanley R, Witschen P, Tolg C, Kaspar RE, Hallstrom C, Gittsovich L, Sulciner ML, Zhang X, Forster CL, Lange CA, Shats O, Desler M, Cowan KH, Yee D, Schwertfeger KL, Turley EA, McCarthy JB, Nelson AC., Free PMC Article | 06/22/2023 |
| Tumor-promoting roles of HMMR in lung adenocarcinoma. | Tumor-promoting roles of HMMR in lung adenocarcinoma.
Wang Q, Wu G, Fu L, Li Z, Wu Y, Zhu T, Yu G. | 05/30/2023 |
| The importance of RHAMM in the normal brain and gliomas: physiological and pathological roles. | The importance of RHAMM in the normal brain and gliomas: physiological and pathological roles.
Pibuel MA, Poodts D, Molinari Y, Díaz M, Amoia S, Byrne A, Hajos S, Lompardía S, Franco P., Free PMC Article | 01/14/2023 |
| RHAMM expression tunes the response of breast cancer cell lines to hyaluronan. | RHAMM expression tunes the response of breast cancer cell lines to hyaluronan.
Carvalho AM, Soares da Costa D, Reis RL, Pashkuleva I. | 06/25/2022 |
| Oleate acid-stimulated HMMR expression by CEBPalpha is associated with nonalcoholic steatohepatitis and hepatocellular carcinoma. | Oleate acid-stimulated HMMR expression by CEBPα is associated with nonalcoholic steatohepatitis and hepatocellular carcinoma.
Zhang D, Liu J, Xie T, Jiang Q, Ding L, Zhu J, Ye Q., Free PMC Article | 04/9/2022 |
| Identification of hub genes associated with prognosis, diagnosis, immune infiltration and therapeutic drug in liver cancer by integrated analysis. | Identification of hub genes associated with prognosis, diagnosis, immune infiltration and therapeutic drug in liver cancer by integrated analysis.
Lei X, Zhang M, Guan B, Chen Q, Dong Z, Wang C., Free PMC Article | 02/5/2022 |
| HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells. | HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C. | 12/11/2021 |
| RHAMM in liver metastases of stage IV colorectal cancer with mismatch-repair proficient status correlates with tumor budding, cytotoxic T-cells and PD-1/PD-L1. | RHAMM in liver metastases of stage IV colorectal cancer with mismatch-repair proficient status correlates with tumor budding, cytotoxic T-cells and PD-1/PD-L1.
Burren S, Reche K, Blank A, Galvàn JA, Dawson H, Berger MD, Zlobec I, Lugli A. | 12/11/2021 |
| CD44 and RHAMM expression patterns in the human developing lung. | CD44 and RHAMM expression patterns in the human developing lung.
Markasz L, Savani RC, Jonzon A, Sindelar R. | 11/27/2021 |
| Expression of the Receptor for Hyaluronic Acid-Mediated Motility (RHAMM) in Endometrial Cancer is Associated With Adverse Histologic Parameters and Tumor Progression. | Expression of the Receptor for Hyaluronic Acid-Mediated Motility (RHAMM) in Endometrial Cancer is Associated With Adverse Histologic Parameters and Tumor Progression.
Schatz-Siemers N, Chen YT, Chen Z, Wang D, Ellenson LH, Du YN., Free PMC Article | 07/24/2021 |
| Hyaluronan-mediated motility receptor expression functions as a prognostic biomarker in uterine carcinosarcoma based on bioinformatics analysis. | Hyaluronan-mediated motility receptor expression functions as a prognostic biomarker in uterine carcinosarcoma based on bioinformatics analysis.
Sun H, Ma L, Chen J., Free PMC Article | 06/19/2021 |
| RHAMM inhibits cell migration via the AKT/GSK3beta/Snail axis in luminal A subtype breast cancer. | RHAMM inhibits cell migration via the AKT/GSK3β/Snail axis in luminal A subtype breast cancer.
Wang J, Li D, Shen W, Sun W, Gao R, Jiang P, Wang L, Liu Y, Chen Y, Zhou W, Wang R, Xiang R, Stupack D, Luo N. | 03/27/2021 |
| A novel mutation combining with rs66612022 in a Chinese pedigree suggests a new pathogenesis to osteogenesis imperfecta via whole genome sequencing. | A novel mutation combining with rs66612022 in a Chinese pedigree suggests a new pathogenesis to osteogenesis imperfecta via whole genome sequencing.
Li Y, Liang H, Yuan D, Liu B, Liu L, Zhang Y, Hou K, Zhang Y, Chen B, Ding J, Li Y, Wang Q, Wu H, Shi H, Hu M. | 03/27/2021 |
| HCG18/miR-34a-5p/HMMR axis accelerates the progression of lung adenocarcinoma. | HCG18/miR-34a-5p/HMMR axis accelerates the progression of lung adenocarcinoma.
Li W, Pan T, Jiang W, Zhao H. | 02/27/2021 |
| CD44 expression showed a statistically significant influence on patients' 5-year survival. However, using a multivariate Cox regression analysis, neither CD44 nor RHAMM confirmed themselves as independent prognostic factors. | The Role of CD44 and RHAMM in Endometrial (Endometrioid Type) Cancer: An Immunohistochemical Study.
Klarić M, Haller H, Brnčić Fischer A, Babarović E, Prijić A, Eminović S. | 07/25/2020 |
| HMMR activates the TGF-beta/Smad2 signaling pathway, which was required for the HMMR-mediated oncogenic effects and exhibited significant clinical relevance with HMMR expression. These findings reveal a critical role for HMMR in the chemoresistance of gastric cancer. | Hyaluronan-mediated motility receptor confers resistance to chemotherapy via TGFβ/Smad2-induced epithelial-mesenchymal transition in gastric cancer.
Zhang H, Ren L, Ding Y, Li F, Chen X, Ouyang Y, Zhang Y, Zhang D. | 05/16/2020 |
| HMMR expression might be a specific prognostic marker in terms of progression-free survival in papillary muscle invasive bladder cancer. | Systematic screening of protein-coding gene expression identified HMMR as a potential independent indicator of unfavorable survival in patients with papillary muscle-invasive bladder cancer.
Yang D, Ma Y, Zhao P, Ma J, He C. | 04/25/2020 |
| Results provide evidence that upregulation of RHAMM(B) is a valuable prognostic marker for pancreatic cancer and demonstrated that only the shorter isoform RHAMM(B), but not RHAMM(A) is significantly upregulated in pancreatic neuroendocrine tumor (PNET) and pancreatic ductal adenocarcinoma (PDAC). Furthermore, RHAMM(B), but not RHAMM(A), is shown to promote PNET metastasis in part through EGFR signaling. | Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression.
Choi S, Wang D, Chen X, Tang LH, Verma A, Chen Z, Kim BJ, Selesner L, Robzyk K, Zhang G, Pang S, Han T, Chan CS, Fahey TJ 3rd, Elemento O, Du YN., Free PMC Article | 04/18/2020 |
| It has shown that RHAMM-target peptides induced apoptosis and inhibited necrosis of tumor cells. RHAMM-target peptide had no effect on fibroblasts (non-tumor cells) and fibroblasts (RHAMM-/-). | [RHAMM (receptor hyaluronan-mediated motility)-target peptides induce apoptosis in prostate cancer cells].
Akentieva NP, Shushanov SS. | 02/9/2019 |
| BACH1 performs stabilization of mitotic spindle orientation together with HMMR and CRM1 in mitosis, and that the cell cycle-specific phosphorylation switches the transcriptional and mitotic functions of BACH1. | Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.
Li J, Shima H, Nishizawa H, Ikeda M, Brydun A, Matsumoto M, Kato H, Saiki Y, Liu L, Watanabe-Matsui M, Iemura K, Tanaka K, Shiraki T, Igarashi K. | 01/12/2019 |
| A mechanism of sense-antisense interference between HMMR and HMMR-AS1 in GBM. | Targeting Long Noncoding RNA HMMR-AS1 Suppresses and Radiosensitizes Glioblastoma.
Li J, Ji X, Wang H., Free PMC Article | 12/22/2018 |
| This pilot study shows, for the first time, that RHAMM may contribute to ovarian cancer disease and could potentially be used as a prognostic marker. | Increased RHAMM expression relates to ovarian cancer progression.
Buttermore ST, Hoffman MS, Kumar A, Champeaux A, Nicosia SV, Kruk PA., Free PMC Article | 06/9/2018 |