| Singed and vinculin play redundant roles in cell migration by regulating F-actin. | Singed and vinculin play redundant roles in cell migration by regulating F-actin.
Khaitan V, Shill K, Chatterjee P, Mukherjee S, Majumder P. | 07/17/2023 |
| Fascin limits Myosin activity within Drosophila border cells to control substrate stiffness and promote migration. | Fascin limits Myosin activity within Drosophila border cells to control substrate stiffness and promote migration.
Lamb MC, Kaluarachchi CP, Lansakara TI, Mellentine SQ, Lan Y, Tivanski AV, Tootle TL., Free PMC Article | 11/22/2021 |
| Fascin regulates protrusions and delamination to mediate invasive, collective cell migration in vivo. | Fascin regulates protrusions and delamination to mediate invasive, collective cell migration in vivo.
Lamb MC, Anliker KK, Tootle TL., Free PMC Article | 09/4/2021 |
| Alterations in nuclear Fascin levels result in defects in nucleolar morphology in both Drosophila follicles and cultured mammalian cells, suggesting that nuclear Fascin plays an important role in nucleolar architecture. | Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture.
Groen CM, Jayo A, Parsons M, Tootle TL., Free PMC Article | 02/13/2016 |
| essential for actin bundle initiation and stiffening during embryonic tracheal system development | Fascin, may the Forked be with you.
Okenve-Ramos P, Llimargas M., Free PMC Article | 10/10/2015 |
| Fascin and Ena cooperate to extend and maintain robust filopodia of uniform thickness with aligned barbed ends by a unique mechanistic cycle. | Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin.
Winkelman JD, Bilancia CG, Peifer M, Kovar DR., Free PMC Article | 05/31/2014 |
| Fascin links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis. | Fascin links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis.
Okenve-Ramos P, Llimargas M. | 04/12/2014 |
| These data lead to the conclusion that prostaglandins regulate Fascin to control actin remodeling | Drosophila Fascin is a novel downstream target of prostaglandin signaling during actin remodeling.
Groen CM, Spracklen AJ, Fagan TN, Tootle TL., Free PMC Article | 05/25/2013 |
| The terminal branchlets of different classes of neurons have distinctive dynamics and are formed on the basis of molecularly separable mechanisms; in particular, class III neurons require fascin for terminal branching whereas class IV neurons do not. | Fascin controls neuronal class-specific dendrite arbor morphology.
Nagel J, Delandre C, Zhang Y, Förstner F, Moore AW, Tavosanis G. | 10/20/2012 |
| The regulatory role of FascinS52 appears to be tissuespecific, and its importance might depend on the dynamics and the turnover rate of actin bundles between various cell types. | Fascin for cell migration in Drosophila.
Zanet J, Payre F, Plaza S. | 03/29/2010 |
| Fascin is required for plasmatocyte migration, both as these cells undergo developmental dispersal and during an inflammatory response to epithelial wounding. | Fascin is required for blood cell migration during Drosophila embryogenesis.
Zanet J, Stramer B, Millard T, Martin P, Payre F, Plaza S. | 01/21/2010 |
| study found that Rab35 regulates the assembly of actin filaments during bristle development; effect was mediated by the actin-bundling protein fascin, which directly associated with active Rab35 | Rab35 controls actin bundling by recruiting fascin as an effector protein.
Zhang J, Fonovic M, Suyama K, Bogyo M, Scott MP. | 01/21/2010 |
| Fascin deficiency does not impair 20-hydroxyecdysone response, but neurites fail to maintain their normal, nearly straight trajectory, instead forming curls and hooks. This is accompanied by abnormally distributed filamentous actin. | Phenotypes of Drosophila brain neurons in primary culture reveal a role for fascin in neurite shape and trajectory.
Kraft R, Escobar MM, Narro ML, Kurtis JL, Efrat A, Barnard K, Restifo LL., Free PMC Article | 01/21/2010 |