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    HNRNPC heterogeneous nuclear ribonucleoprotein C [ Homo sapiens (human) ]

    Gene ID: 3183, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    HNRNPC mediates lymphatic metastasis of cervical cancer through m6A-dependent alternative splicing of FOXM1.

    HNRNPC mediates lymphatic metastasis of cervical cancer through m6A-dependent alternative splicing of FOXM1.
    Liu YY, Xia M, Chen ZB, Liao YD, Zhang CY, Yuan L, Pan YW, Huang H, Lu HW, Yao SZ., Free PMC Article

    10/8/2024
    The m6A reader HNRNPC promotes glioma progression by enhancing the stability of IRAK1 mRNA through the MAPK pathway.

    The m6A reader HNRNPC promotes glioma progression by enhancing the stability of IRAK1 mRNA through the MAPK pathway.
    Chen JJ, Lu TZ, Wang T, Yan WH, Zhong FY, Qu XH, Gong XC, Li JG, Tou FF, Jiang LP, Han XJ., Free PMC Article

    10/4/2024
    Identification of RNA-binding protein hnRNP C targeting the 3'UTR of the TAP-associated glycoprotein tapasin in melanoma.

    Identification of RNA-binding protein hnRNP C targeting the 3'UTR of the TAP-associated glycoprotein tapasin in melanoma.
    Wang Y, Seliger B., Free PMC Article

    07/24/2024
    DUSP3 modulates IRES-dependent translation of mRNAs through dephosphorylation of the HNRNPC protein in cells under genotoxic stimulus.

    DUSP3 modulates IRES-dependent translation of mRNAs through dephosphorylation of the HNRNPC protein in cells under genotoxic stimulus.
    Ferruzo PYM, Boell VK, Russo LC, Oliveira CC, Forti FL.

    06/5/2024
    N6-Methyladenosine reader HNRNPC-mediated downregulation of circITCH prevents miR-224-3p sequestering and contributes to tumorigenesis in nasopharyngeal carcinoma.

    N6-Methyladenosine reader HNRNPC-mediated downregulation of circITCH prevents miR-224-3p sequestering and contributes to tumorigenesis in nasopharyngeal carcinoma.
    Zhou Q, Song W, Li X, Lin J, Zhu C, Cao L, Li W, Lin S.

    05/6/2024
    HNRNPC promotes estrogen receptor-positive breast cancer cell cycle by stabilizing WDR77 mRNA in an m6A-dependent manner.

    HNRNPC promotes estrogen receptor-positive breast cancer cell cycle by stabilizing WDR77 mRNA in an m6A-dependent manner.
    Xu W, Huang Z, Xiao Y, Li W, Xu M, Zhao Q, Yi P.

    04/25/2024
    HNRNPC Regulates GLUT1/LDHA Pathway by Stabilizing FOXM1 mRNA to Promote the Progression and Aerobic Glycolysis of Multiple Myeloma.

    HNRNPC Regulates GLUT1/LDHA Pathway by Stabilizing FOXM1 mRNA to Promote the Progression and Aerobic Glycolysis of Multiple Myeloma.
    Wu N, Zhu Y.

    04/4/2024
    Hsa_circ_0014606 Derived from Exosomes Promotes Gastric Carcinoma Tumorigenesis and Proliferation by Sponging miR-514b-3p to Upregulate HNRNPC.

    Hsa_circ_0014606 Derived from Exosomes Promotes Gastric Carcinoma Tumorigenesis and Proliferation by Sponging miR-514b-3p to Upregulate HNRNPC.
    Jiang T, Xu L, Qu X, Li R, Cheng Y, He H.

    03/26/2024
    m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.

    m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
    Wu Z, Zuo X, Zhang W, Li Y, Gui R, Leng J, Shen H, Pan B, Fan L, Li J, Jin H., Free PMC Article

    12/18/2023
    HNRNPC mediated m[6]A methylation of 5-methyltetrahydrofolate-homocysteine methyltransferase and involved in the occurrence of RSA.

    HNRNPC mediated m(6)A methylation of 5-methyltetrahydrofolate-homocysteine methyltransferase and involved in the occurrence of RSA.
    Zhang M, Huang N, Gao Y, Feng Z, Kang B, Guo H, Jiang J, Liao S, Wang H.

    12/6/2023
    FOXM1a Isoform of Oncogene FOXM1 Is a Tumor Suppressor Suppressed by hnRNP C in Oral Squamous Cell Carcinoma.

    FOXM1a Isoform of Oncogene FOXM1 Is a Tumor Suppressor Suppressed by hnRNP C in Oral Squamous Cell Carcinoma.
    Jia R, Che X, Jia J, Guo J., Free PMC Article

    10/5/2023
    Circular RNA circ-FIRRE interacts with HNRNPC to promote esophageal squamous cell carcinoma progression by stabilizing GLI2 mRNA.

    Circular RNA circ-FIRRE interacts with HNRNPC to promote esophageal squamous cell carcinoma progression by stabilizing GLI2 mRNA.
    Zhou Y, Xue X, Luo J, Li P, Xiao Z, Zhang W, Zhou J, Li P, Zhao J, Ge H, Tian Z, Zhao X., Free PMC Article

    09/6/2023
    Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy.

    Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy.
    Guo M, He M, Zhang Y, Liu W, Qi M, Liu Z, Yi G, Deng S, Li Y, Sun X, Zhao L, Chen T, Liu Y., Free PMC Article

    08/22/2023
    HnRNP Pathologies in Frontotemporal Lobar Degeneration.

    HnRNP Pathologies in Frontotemporal Lobar Degeneration.
    Jiang X, Gatt A, Lashley T., Free PMC Article

    07/5/2023
    HNRNPC suppresses tumor immune microenvironment by activating Treg cells promoting the progression of prostate cancer.

    HNRNPC suppresses tumor immune microenvironment by activating Treg cells promoting the progression of prostate cancer.
    Cheng Y, Li L, Wei X, Xu F, Huang X, Qi F, Zhang Y, Li X., Free PMC Article

    05/5/2023
    N6-methylation of RNA-bound adenosine regulator HNRNPC promotes vascular endothelial dysfunction in type 2 diabetes mellitus by activating the PSEN1-mediated Notch pathway.

    N6-methylation of RNA-bound adenosine regulator HNRNPC promotes vascular endothelial dysfunction in type 2 diabetes mellitus by activating the PSEN1-mediated Notch pathway.
    Cai Y, Chen T, Wang M, Deng L, Li C, Fu S, Xie K.

    03/16/2023
    Identification and Validation of Three m6A Regulators: FTO, HNRNPC, and HNRNPA2B1 as Potential Biomarkers for Endometriosis.

    Identification and Validation of Three m6A Regulators: FTO, HNRNPC, and HNRNPA2B1 as Potential Biomarkers for Endometriosis.
    Sun J, Gan L, Sun J., Free PMC Article

    02/11/2023
    HNRNPC, a predictor of prognosis and immunotherapy response based on bioinformatics analysis, is related to proliferation and invasion of NSCLC cells.

    HNRNPC, a predictor of prognosis and immunotherapy response based on bioinformatics analysis, is related to proliferation and invasion of NSCLC cells.
    Gu Z, Yang Y, Ma Q, Wang H, Zhao S, Qi Y, Li Y., Free PMC Article

    12/31/2022
    Construction and clinical evaluation of N6-methyladenosine risk signature of YTHDC2, IGF2BP2, and HNRNPC in head and neck squamous cell carcinoma.

    Construction and clinical evaluation of N6-methyladenosine risk signature of YTHDC2, IGF2BP2, and HNRNPC in head and neck squamous cell carcinoma.
    Yue Q, Xu L, Zhang D., Free PMC Article

    11/26/2022
    HNRNPC downregulation inhibits IL-6/STAT3-mediated HCC metastasis by decreasing HIF1A expression.

    HNRNPC downregulation inhibits IL-6/STAT3-mediated HCC metastasis by decreasing HIF1A expression.
    Liu D, Luo X, Xie M, Zhang T, Chen X, Zhang B, Sun M, Wang Y, Feng Y, Ji X, Li Y, Liu B, Huang W, Xia L., Free PMC Article

    10/15/2022
    HNRNPC regulates RhoA to induce DNA damage repair and cancer-associated fibroblast activation causing radiation resistance in pancreatic cancer.

    HNRNPC regulates RhoA to induce DNA damage repair and cancer-associated fibroblast activation causing radiation resistance in pancreatic cancer.
    Xia N, Yang N, Shan Q, Wang Z, Liu X, Chen Y, Lu J, Huang W, Wang Z., Free PMC Article

    04/23/2022
    A systematic pan-cancer study demonstrates the oncogenic function of heterogeneous nuclear ribonucleoprotein C.

    A systematic pan-cancer study demonstrates the oncogenic function of heterogeneous nuclear ribonucleoprotein C.
    Pan C, Wu Q, Feng N., Free PMC Article

    04/16/2022
    Identification of HnRNPC as a novel Tau exon 10 splicing factor using RNA antisense purification mass spectrometry.

    Identification of HnRNPC as a novel Tau exon 10 splicing factor using RNA antisense purification mass spectrometry.
    Xing S, Wang J, Wu R, Hefti MM, Crary JF, Lu Y., Free PMC Article

    03/19/2022
    HNRNPC impedes m(6)A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma.

    HNRNPC impedes m(6)A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma.
    Huang XT, Li JH, Zhu XX, Huang CS, Gao ZX, Xu QC, Zhao W, Yin XY.

    01/8/2022
    ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses.

    ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses.
    Herzner AM, Khan Z, Van Nostrand EL, Chan S, Cuellar T, Chen R, Pechuan-Jorge X, Komuves L, Solon M, Modrusan Z, Haley B, Yeo GW, Behrens TW, Albert ML., Free PMC Article

    11/27/2021
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