| Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1. | Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1.
Chen J, Mao M, Ma Z, Liu J, Jiang M, Chen G, Xu Y., Free PMC Article | 04/18/2024 |
| The homeoprotein HOXB2 limits triple-negative breast carcinogenesis via extracellular matrix remodeling. | The homeoprotein HOXB2 limits triple-negative breast carcinogenesis via extracellular matrix remodeling.
Oh JH, Kim CY, Jeong DS, Kim YC, Kim MH, Cho JY., Free PMC Article | 03/12/2024 |
| High expression of homeobox B2 predicts poor survival of colon adenocarcinoma by enhancing tumor proliferation and invasion. | High expression of homeobox B2 predicts poor survival of colon adenocarcinoma by enhancing tumor proliferation and invasion.
Li S, Wang Y, Xuan Z, Zhang Y, Miao Z. | 02/11/2023 |
| HOXB-AS1 accelerates the tumorigenesis of glioblastoma via modulation of HOBX2 and HOBX3 at transcriptional and posttranscriptional levels. | HOXB-AS1 accelerates the tumorigenesis of glioblastoma via modulation of HOBX2 and HOBX3 at transcriptional and posttranscriptional levels.
Bi Y, Mao Y, Su Z, Du J, Ye L, Xu F. | 09/4/2021 |
| LINC00662 promotes cell viability and metastasis in esophageal squamous cell carcinoma by sponging miR-340-5p and upregulating HOXB2. | LINC00662 promotes cell viability and metastasis in esophageal squamous cell carcinoma by sponging miR-340-5p and upregulating HOXB2.
Zhang Z, Liang X, Ren L, Zhang S, Li S, Wan T, Xu D, Lv S., Free PMC Article | 08/14/2021 |
| Estrogen suppresses HOXB2 expression via ERalpha in breast cancer cells. | Estrogen suppresses HOXB2 expression via ERα in breast cancer cells.
Kumar A, Dhillon A, Manjegowda MC, Singh N, Mary DJSJ, Kumar S, Modi D, Limaye AM. | 06/26/2021 |
| Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma. | Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma.
Xu F, Liu Z, Liu R, Lu C, Wang L, Mao W, Zhu Q, Shou H, Zhang K, Li Y, Chu Y, Gu J, Ge D., Free PMC Article | 06/12/2021 |
| miR1395p enhances cisplatin sensitivity in nonsmall cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox protein HoxB2. | miR‑139‑5p enhances cisplatin sensitivity in non‑small cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox protein Hox‑B2.
Du H, Bao Y, Liu C, Zhong A, Niu Y, Tang X., Free PMC Article | 05/8/2021 |
| MiR-202-5p suppressed cell proliferation, migration and invasion in ovarian cancer via regulating HOXB2. | MiR-202-5p suppressed cell proliferation, migration and invasion in ovarian cancer via regulating HOXB2.
Yu HY, Pan SS. | 03/20/2021 |
| HOXB2 and FOXC1 synergistically drive the progression of Wilms tumor. | HOXB2 and FOXC1 synergistically drive the progression of Wilms tumor.
Jing P, Zou J, Zhang L, Wang C, Yang Y, Deng L, Zhao D. | 10/31/2020 |
| circ-0001785 regulates the pathogenesis of osteosarcoma by sponging miR-1200 to up-regulate HOXB2 expression. | Circular RNA 0001785 regulates the pathogenesis of osteosarcoma as a ceRNA by sponging miR-1200 to upregulate HOXB2.
Li S, Pei Y, Wang W, Liu F, Zheng K, Zhang X., Free PMC Article | 06/13/2020 |
| Results provide evidence that increased HOXB2 expression in papillary bladder cancer (BC) can promote growth and adhesion of BC cells. | HOXB2 is a Putative Tumour Promotor in Human Bladder Cancer.
Liu J, Li S, Cheng X, DU P, Yang Y, Jiang WG. | 12/14/2019 |
| SNP rs10853100 is associated with lower levels of HOXB2 expression in lung tumor samples. HOXB2 mRNA and protein levels are significantly lower in lung tumors compared to non-tumor lung tissues. | Lung cancer susceptibility genetic variants modulate HOXB2 expression in the lung.
Clemenceau A, Boucherat O, Landry-Truchon K, Lamontagne M, Biardel S, Joubert P, Gobeil S, Secco B, Laplante M, Morissette M, Obeidat M, Timens W, Jeannotte L, Bossé Y. | 06/29/2019 |
| HOXB2 and HOXB3 act as tumor suppressors in acute myeloid leukemia patients carrying the FLT3 protein mutations. | The role of HOXB2 and HOXB3 in acute myeloid leukemia.
Lindblad O, Chougule RA, Moharram SA, Kabir NN, Sun J, Kazi JU, Rönnstrand L. | 05/7/2016 |
| Increased expression of HOXB2 protein is associated with HPV infection and cervical cancer progression. | Increased expression of HOXB2 and HOXB13 proteins is associated with HPV infection and cervical cancer progression.
Gonzalez-Herrera A, Salgado-Bernabe M, Velazquez-Velazquez C, Salcedo-Vargas M, Andrade-Manzano A, Avila-Moreno F, Pina-Sanchez P. | 12/12/2015 |
| HOXB2 acts as a negative tumor growth regulator, decreasing proliferation in mammary adenocarcinoma tumors. | A functional in vivo screen for regulators of tumor progression identifies HOXB2 as a regulator of tumor growth in breast cancer.
Boimel PJ, Cruz C, Segall JE., Free PMC Article | 12/31/2011 |
| hoxb2 and hoxb4 expression is related to erythroid hematopoiesis, and hoxb4 has greater relevance to erythroid hematopoiesis as compared with hoxb2. | [Effect of ATRA on the expression of genes Hoxb2 and Hoxb4 in cord blood erythroid progenitors].
DU CQ, Huang MX, Liu WJ. | 08/27/2011 |
| Downregulation of HoxB2, HoxB4 and Alx4 expression during the narrow window of early embryogenesis may cause omphalocele in the Cd chick model by interfering with molecular signaling required for proper VBW formation. | HoxB2, HoxB4 and Alx4 genes are downregulated in the cadmium-induced omphalocele in the chick model.
Doi T, Puri P, Bannigan J, Thompson J. | 03/5/2011 |
| Meta-analysis of gene-disease association. (HuGE Navigator) | Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
Johnatty SE, Beesley J, Chen X, Macgregor S, Duffy DL, Spurdle AB, deFazio A, Gava N, Webb PM, Rossing MA, Doherty JA, Goodman MT, Lurie G, Thompson PJ, Wilkens LR, Ness RB, Moysich KB, Chang-Claude J, Wang-Gohrke S, Cramer DW, Terry KL, Hankinson SE, Tworoger SS, Garcia-Closas M, Yang H, Lissowska J, Chanock SJ, Pharoah PD, Song H, Whitemore AS, Pearce CL, Stram DO, Wu AH, Pike MC, Gayther SA, Ramus SJ, Menon U, Gentry-Maharaj A, Anton-Culver H, Ziogas A, Hogdall E, Kjaer SK, Hogdall C, Berchuck A, Schildkraut JM, Iversen ES, Moorman PG, Phelan CM, Sellers TA, Cunningham JM, Vierkant RA, Rider DN, Goode EL, Haviv I, Chenevix-Trench G, Ovarian Cancer Association Consortium, Australian Ovarian Cancer Study Group, Australian Cancer Study (Ovarian Cancer)., Free PMC Article | 09/15/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.
Pillas D, Hoggart CJ, Evans DM, O'Reilly PF, Sipilä K, Lähdesmäki R, Millwood IY, Kaakinen M, Netuveli G, Blane D, Charoen P, Sovio U, Pouta A, Freimer N, Hartikainen AL, Laitinen J, Vaara S, Glaser B, Crawford P, Timpson NJ, Ring SM, Deng G, Zhang W, McCarthy MI, Deloukas P, Peltonen L, Elliott P, Coin LJ, Smith GD, Jarvelin MR., Free PMC Article | 04/7/2010 |
| Data show that inducible Hox genes are selectively sensitive to the inhibition of actin polymerization and that actin polymerization is required for the assembly of a transcription complex on the regulatory region of the Hox genes. | Induction of HoxB transcription by retinoic acid requires actin polymerization.
Ferrai C, Naum-Onganía G, Longobardi E, Palazzolo M, Disanza A, Diaz VM, Crippa MP, Scita G, Blasi F., Free PMC Article | 02/22/2010 |
| HOXB2 up-regulated lesions to have much higher HOXB2 expression than the corresponding normal tissue. | HOXB2 as a novel prognostic indicator for stage I lung adenocarcinomas.
Inamura K, Togashi Y, Okui M, Ninomiya H, Hiramatsu M, Satoh Y, Okumura S, Nakagawa K, Shimoji T, Noda T, Ishikawa Y. | 01/21/2010 |
| Hoxb2 is a direct target for regulation by PLZF in the developing CNS and suggest that deregulation of Hox gene expression may contribute to APL pathogenesis. | Regulation of Hoxb2 by APL-associated PLZF protein.
Ivins S, Pemberton K, Guidez F, Howell L, Krumlauf R, Zelent A. | 01/21/2010 |