| Sequential gene expression analysis of myelodysplastic syndrome transformation identifies HOXB3 and HOXB7 as the novel targets for mesenchymal cells in disease. | Sequential gene expression analysis of myelodysplastic syndrome transformation identifies HOXB3 and HOXB7 as the novel targets for mesenchymal cells in disease.
Yin C, Li Y, Zhang C, Zang S, Wang Z, Yan X, Ma T, Li X, Li W., Free PMC Article | 02/12/2024 |
| HOXB3 drives WNT-activation associated progression in castration-resistant prostate cancer. | HOXB3 drives WNT-activation associated progression in castration-resistant prostate cancer.
Zhu S, Yang Z, Zhang Z, Zhang H, Li S, Wu T, Chen X, Guo J, Wang A, Tian H, Yu J, Zhang C, Su L, Shang Z, Quan C, Niu Y., Free PMC Article | 04/4/2023 |
| Extracellular Vesicle-Encapsulated MicroRNA-375 from Bone Marrow-Derived Mesenchymal Stem Cells Inhibits Hepatocellular Carcinoma Progression through Regulating HOXB3-Mediated Wnt/beta-Catenin Pathway. | Extracellular Vesicle-Encapsulated MicroRNA-375 from Bone Marrow-Derived Mesenchymal Stem Cells Inhibits Hepatocellular Carcinoma Progression through Regulating HOXB3-Mediated Wnt/β-Catenin Pathway.
Yu Z, Liu J, Fan Q, Yu J, Ren X, Wang X., Free PMC Article | 04/16/2022 |
| Levels of serum Hoxb3 and sFlt-1 in pre-eclamptic patients and their effects on pregnancy outcomes. | Levels of serum Hoxb3 and sFlt-1 in pre-eclamptic patients and their effects on pregnancy outcomes.
Zhou J, Guo X, Sun Y, Ma L, Zhe R. | 08/14/2021 |
| CSF levels of HoxB3 and YKL-40 may predict conversion from clinically isolated syndrome to relapsing remitting multiple sclerosis. | CSF levels of HoxB3 and YKL-40 may predict conversion from clinically isolated syndrome to relapsing remitting multiple sclerosis.
Tamam Y, Gunes B, Akbayir E, Kizilay T, Karaaslan Z, Koral G, Duzel B, Kucukali CI, Gunduz T, Kurtuncu M, Yilmaz V, Tuzun E, Turkoglu R. | 06/19/2021 |
| miR-7 Reduces High Glucose Induced-damage Via HoxB3 and PI3K/AKT/mTOR Signaling Pathways in Retinal Pigment Epithelial Cells. | miR-7 Reduces High Glucose Induced-damage Via HoxB3 and PI3K/AKT/mTOR Signaling Pathways in Retinal Pigment Epithelial Cells.
Yang Z, Hu H, Zou Y, Luo W, Xie L, You Z. | 06/12/2021 |
| Data indicate a miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry which contributes to leukemogenesis and suggest a therapeutic strategy of restoring miR-375 expression in Acute myeloid leukemia (AML). | A novel miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry contributes to leukemogenesis in acute myeloid leukemia.
Bi L, Zhou B, Li H, He L, Wang C, Wang Z, Zhu L, Chen M, Gao S., Free PMC Article | 08/25/2018 |
| HOXA4/HOXB3 gene expression-based risk score may be useful for prognostic risk stratification and warrants prospective validation in HGSOC patients. | HOXA4/HOXB3 gene expression signature as a biomarker of recurrence in patients with high-grade serous ovarian cancer following primary cytoreductive surgery and first-line adjuvant chemotherapy.
Miller KR, Patel JN, Zhang Q, Norris EJ, Symanowski J, Michener C, Sehouli J, Braicu I, Destephanis DD, Sutker AP, Jones W, Livasy CA, Biscotti C, Ganapathi RN, Tait DL, Ganapathi MK. | 07/14/2018 |
| HOXB3 is degraded by miR-375 in breast cancer cells.HOXB3 plays role in tamoxifen resistance. | miR-375 inhibits cancer stem cell phenotype and tamoxifen resistance by degrading HOXB3 in human ER-positive breast cancer.
Fu H, Fu L, Xie C, Zuo WS, Liu YS, Zheng MZ, Yu JM. | 03/25/2017 |
| miR-10b might control cell apoptosis, proliferation, migration, and invasion in endometrial cancer via regulation of HOXB3 expression. | miR-10b Inhibits Apoptosis and Promotes Proliferation and Invasion of Endometrial Cancer Cells via Targeting HOXB3.
Chen H, Fan Y, Xu W, Chen J, Xu C, Wei X, Fang D, Feng Y. | 02/4/2017 |
| HOXB2 and HOXB3 act as tumor suppressors in acute myeloid leukemia patients carrying the FLT3 protein mutations. | The role of HOXB2 and HOXB3 in acute myeloid leukemia.
Lindblad O, Chougule RA, Moharram SA, Kabir NN, Sun J, Kazi JU, Rönnstrand L. | 05/7/2016 |
| decreased methylation at HOXB3 and HOXB4 was associated with increased gene expression of both HOXB genes specific to the mid-risk AML, while increased DNA methylation at DCC distinctive to the high-risk AML was associated with increased gene expression | Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemia.
Qu X, Davison J, Du L, Storer B, Stirewalt DL, Heimfeld S, Estey E, Appelbaum FR, Fang M., Free PMC Article | 03/12/2016 |
| describe familial cases of TH in two generations (proband and his father), in addition to other two sporadic cases. We have found polymorphisms in the HOXB3, HOXD3, and a new synonymous variant, and PITX2 genes | The absence of mutations in homeobox candidate genes HOXA3, HOXB3, HOXD3 and PITX2 in familial and sporadic thyroid hemiagenesis.
Kizys MM, Nesi-França S, Cardoso MG, Harada MY, Melo MC, Chiamolera MI, Dias-da-Silva MR, Maciel RM. | 11/22/2014 |
| HoxB3 promote prostate cancer progression by upregulating CDCA3 expression. | HoxB3 promotes prostate cancer cell progression by transactivating CDCA3.
Chen J, Zhu S, Jiang N, Shang Z, Quan C, Niu Y. | 04/6/2013 |
| Data show that inducible Hox genes are selectively sensitive to the inhibition of actin polymerization and that actin polymerization is required for the assembly of a transcription complex on the regulatory region of the Hox genes. | Induction of HoxB transcription by retinoic acid requires actin polymerization.
Ferrai C, Naum-Onganía G, Longobardi E, Palazzolo M, Disanza A, Diaz VM, Crippa MP, Scita G, Blasi F., Free PMC Article | 02/22/2010 |
| RASSF1A silencing strongly correlates with overexpression of HOXB3 and DNMT3B. | Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression.
Palakurthy RK, Wajapeyee N, Santra MK, Gazin C, Lin L, Gobeil S, Green MR., Free PMC Article | 01/21/2010 |
| HOXA7, HOXB3, HOXA3, and HOXB13 expression levels changed during angiogenesis, sugessting these proteins might be involved in the angiogenesis of hMSCs. | HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells.
Chung N, Jee BK, Chae SW, Jeon YW, Lee KH, Rha HK. | 01/21/2010 |
| Data report novel nucleoporin 98 fusions with homeobox (HOX)A10, HOXB3 and HOXB4, and describe the results of coexpression of these proteins with the Hox cofactor Meis1 in leukemic induction. | Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1.
Pineault N, Abramovich C, Ohta H, Humphries RK., Free PMC Article | 01/21/2010 |
| The HOXb3 was only weakly expressed in the inv(7) positive patients. | A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias.
Speleman F, Cauwelier B, Dastugue N, Cools J, Verhasselt B, Poppe B, Van Roy N, Vandesompele J, Graux C, Uyttebroeck A, Boogaerts M, De Moerloose B, Benoit Y, Selleslag D, Billiet J, Robert A, Huguet F, Vandenberghe P, De Paepe A, Marynen P, Hagemeijer A. | 01/21/2010 |