| Sequential gene expression analysis of myelodysplastic syndrome transformation identifies HOXB3 and HOXB7 as the novel targets for mesenchymal cells in disease. | Sequential gene expression analysis of myelodysplastic syndrome transformation identifies HOXB3 and HOXB7 as the novel targets for mesenchymal cells in disease.
Yin C, Li Y, Zhang C, Zang S, Wang Z, Yan X, Ma T, Li X, Li W., Free PMC Article | 02/12/2024 |
| MIR143HG promotes methylation of transcription factor HOXB7 promoter by recruiting methyltransferase DNMT1 to prevent the progression of colon cancer. | MIR143HG promotes methylation of transcription factor HOXB7 promoter by recruiting methyltransferase DNMT1 to prevent the progression of colon cancer.
Zhu M, Xu T, Ji L, Jiang B, Wu K. | 12/27/2023 |
| Circ_0068631 sponges miR-139-5p to promote the growth and metastasis of cutaneous squamous cell carcinoma by upregulating HOXB7. | Circ_0068631 sponges miR-139-5p to promote the growth and metastasis of cutaneous squamous cell carcinoma by upregulating HOXB7.
Ji J, Xiong C, Peng J, Zhang N, Zhang Y, Yang H, Zhu W., Free PMC Article | 02/27/2023 |
| Long non-coding RNA BBOX1-AS1 exacerbates esophageal squamous cell carcinoma development by regulating HOXB7/beta-catenin axis. | Long non-coding RNA BBOX1-AS1 exacerbates esophageal squamous cell carcinoma development by regulating HOXB7/β-catenin axis.
Sheng J, Zhou M, Wang C, Jia J, Chu J, Ju C, Wan J, He J, He F. | 07/23/2022 |
| Epigenetic Regulation of CDH1 Is Altered after HOXB7-Silencing in MDA-MB-468 Triple-Negative Breast Cancer Cells. | Epigenetic Regulation of CDH1 Is Altered after HOXB7-Silencing in MDA-MB-468 Triple-Negative Breast Cancer Cells.
Paço A, Leitão-Castro J, Freitas R., Free PMC Article | 02/12/2022 |
| HOXB7 mediates cisplatin resistance in esophageal squamous cell carcinoma through involvement of DNA damage repair. | HOXB7 mediates cisplatin resistance in esophageal squamous cell carcinoma through involvement of DNA damage repair.
Zhou T, Fu H, Dong B, Dai L, Yang Y, Yan W, Shen L., Free PMC Article | 08/7/2021 |
| MiR-513a-3p inhibits EMT mediated by HOXB7 and promotes sensitivity to cisplatin in ovarian cancer cells. | MiR-513a-3p inhibits EMT mediated by HOXB7 and promotes sensitivity to cisplatin in ovarian cancer cells.
Chen Y, Zhao XH, Zhang DD, Zhao Y. | 07/3/2021 |
| Silencing of hsa_circ_0009035 Suppresses Cervical Cancer Progression and Enhances Radiosensitivity through MicroRNA 889-3p-Dependent Regulation of HOXB7. | Silencing of hsa_circ_0009035 Suppresses Cervical Cancer Progression and Enhances Radiosensitivity through MicroRNA 889-3p-Dependent Regulation of HOXB7.
Zhao X, Dong W, Luo G, Xie J, Liu J, Yu F., Free PMC Article | 06/19/2021 |
| CircRNA hsa_circ_0070934 functions as a competitive endogenous RNA to regulate HOXB7 expression by sponging miR12363p in cutaneous squamous cell carcinoma. | CircRNA hsa_circ_0070934 functions as a competitive endogenous RNA to regulate HOXB7 expression by sponging miR‑1236‑3p in cutaneous squamous cell carcinoma.
Zhang DW, Wu HY, Zhu CR, Wu DD., Free PMC Article | 05/8/2021 |
| The let-7c/HoxB7 axis regulates the cell proliferation, migration and apoptosis in hepatocellular carcinoma. | The let-7c/HoxB7 axis regulates the cell proliferation, migration and apoptosis in hepatocellular carcinoma.
Cai L, Wang Z, Zheng H, Xu L. | 10/24/2020 |
| High HOXB7 expression is associated with prostate cancer. | The relationship between homeobox B7 expression and the clinical characteristics of patient with prostate cancer.
Song Z, Liao Z, Cui Y, Yang C. | 07/11/2020 |
| upregulated MMP2, MMP9, VEGFa, and IL8 expression via the ERK pathway to accelerate the malignant progression of intrahepatic cholangiocarcinoma | Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis.
Dai L, Hu W, Yang Z, Chen D, He B, Chen Y, Zhou L, Xie H, Wu J, Zheng S., Free PMC Article | 06/27/2020 |
| High expression of HOXB7 protein was associated with poor prognosis of patients with digestive system cancers, as well as clinicopathologic characteristics, including the tumor invasion, lymph node status, distant metastasis and TNM stage | Deregulated HOXB7 expression predicts poor prognosis of patients with malignancies of digestive system.
Liu FT, Chen HM, Xiong Y, Zhu ZM. | 06/6/2020 |
| inhibited trophoblast cell differentiation by down-regulating DKK1 expression | Down-regulation of DKK1 and Wnt1/β-catenin pathway by increased homeobox B7 resulted in cell differentiation suppression of intrauterine fetal growth retardation in human placenta.
Huang L, Ying H, Chen Z, Zhu YL, Gu Y, Hu L, Chen D, Zhong N. | 05/2/2020 |
| HOXB7 increased AD-MSC proliferation potential, reduced senescence, and improved chondrogenesis together with a significant increase of basic fibroblast growth factor (bFGF) secretion. | Impact of HOXB7 overexpression on human adipose-derived mesenchymal progenitors.
Foppiani EM, Candini O, Mastrolia I, Murgia A, Grisendi G, Samarelli AV, Boscaini G, Pacchioni L, Pinelli M, De Santis G, Horwitz EM, Veronesi E, Dominici M., Free PMC Article | 04/25/2020 |
| HOXB7 upregulation reversed the effect of miR-384 by promoting CAP in vitro proliferation and migration. | MicroRNA-384 is lowly expressed in human prostate cancer cells and has anti-tumor functions by acting on HOXB7.
Hong Z, Fu W, Wang Q, Zeng Y, Qi L. | 08/31/2019 |
| silencing of the HOXB7 has the mechanism of inactivating the Wnt/beta-catenin signaling pathway, thereby accelerating cell apoptosis and suppressing cell migration and invasion in cutaneous squamous cell carcinoma (CSCC), which could provide a candidate target for the CSCC treatment | Specific knockdown of HOXB7 inhibits cutaneous squamous cell carcinoma cell migration and invasion while inducing apoptosis via the Wnt/β-catenin signaling pathway.
Gao D, Chen HQ. | 07/6/2019 |
| HOXB7 upregulates several canonical embryonic stem cell/induced pluripotent stem cell markers and sustains the expansion of a subpopulation of cells with stem cell characteristics, through modulation of LIN28B, an emerging cancer gene and pluripotency factor, which is a direct target of HOXB7. | HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype.
Monterisi S, Lo Riso P, Russo K, Bertalot G, Vecchi M, Testa G, Di Fiore PP, Bianchi F. | 03/9/2019 |
| High HOXB7 expression is associated with acute lymphoblastic leukemia. | Inhibition of HOXB7 suppresses p27-mediated acute lymphoblastic leukemia by regulating basic fibroblast growth factor and ERK1/2.
Zhong Y, Zhang Y, Ma D, Ren X, Xu C, Wan D. | 03/2/2019 |
| hsa_circ_0074362 plays a crucial role in glioma progression by regulating the miR-1236-3p/HOXB7 pathway. | Circular RNA hsa_circ_0074362 Promotes Glioma Cell Proliferation, Migration, and Invasion by Attenuating the Inhibition of miR-1236-3p on HOXB7 Expression.
Duan X, Liu D, Wang Y, Chen Z. | 11/24/2018 |
| miR-196b-5p inhibition led to significantly increased colorectal cancer cell migration/invasion and metastases formation in mice, whereas ectopic overexpression showed the opposite phenotype. Molecular profiling and target confirmation identified an interaction between miR-196b-5p and HOXB7 and GALNT5, which in turn regulated colorectal cancer cell migration | miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.
Stiegelbauer V, Vychytilova-Faltejskova P, Karbiener M, Pehserl AM, Reicher A, Resel M, Heitzer E, Ivan C, Bullock M, Ling H, Deutsch A, Wulf-Goldenberg A, Adiprasito JB, Stoeger H, Haybaeck J, Svoboda M, Stotz M, Hoefler G, Slaby O, Calin GA, Gerger A, Pichler M. | 06/23/2018 |
| The expression of HOXB7 was upregulated in osteosarcoma tissues and cells compared with paired adjacent nontumor bone tissues and osteoblastic cells using reverse transcriptionquantitative polymer chain reaction and western blotting. HOXB7 knockdown dramatically suppressed cell viability, proliferation, migration and epithelialmesenchymal transition. | Upregulation of HOXB7 promotes proliferation and metastasis of osteosarcoma cells.
Yang Y, Chen J, Chen Q. | 05/5/2018 |
| downregulation of HOXB7 inhibited proliferation, invasion, and tumorigenesis, partly through suppressing the PI3K/Akt signaling pathway in osteosarcoma cells. | Downregulation of Homeobox B7 Inhibits the Tumorigenesis and Progression of Osteosarcoma.
Yang L, Xie F, Li S., Free PMC Article | 04/28/2018 |
| HOXB7 promotes HCC cell proliferation, migration, and invasion through the bFGF-induced MAPK/ERK pathway activation. It might be a novel prognostic factor in HCC and a promising therapeutic target for tumor metastasis and recurrence. | HOXB7 promotes tumor progression via bFGF-induced activation of MAPK/ERK pathway and indicated poor prognosis in hepatocellular carcinoma.
Wang WM, Xu Y, Wang YH, Sun HX, Sun YF, He YF, Zhu QF, Hu B, Zhang X, Xia JL, Qiu SJ, Zhou J, Yang XR, Fan J., Free PMC Article | 04/28/2018 |
| Overexpression of HOXB7 was significantly correlated with poor prognosis of HCC. HOXB7 up-regulated c-Myc and Slug expression via the AKT pathway to promote the acquisition of stem-like properties and facilitate epithelial-mesenchymal transition of hepatoma cells, accelerating the malignant progression of HCC. | HOXB7 accelerates the malignant progression of hepatocellular carcinoma by promoting stemness and epithelial-mesenchymal transition.
Huan HB, Yang DP, Wen XD, Chen XJ, Zhang L, Wu LL, Bie P, Xia F., Free PMC Article | 04/7/2018 |