| HOXB9 promotes osteosarcoma cell survival and malignancy under glucose starvation via upregulating SPP1 expression. | HOXB9 promotes osteosarcoma cell survival and malignancy under glucose starvation via upregulating SPP1 expression.
Han J, Ji R, Zheng S, Xia X, Du W, He H, Han C, Zhao W, Li X, Wang Y, Zhang L. | 05/28/2024 |
| HOXB9 promotes laryngeal squamous cell carcinoma progression by upregulating MMP12. | HOXB9 promotes laryngeal squamous cell carcinoma progression by upregulating MMP12.
Sun C, Deng H, Li Q, Wang P, Chen Y, Sun Y, Han C. | 05/1/2024 |
| Homeobox B9 Promotes Colon Cancer Progression by Targeting SRSF3. | Homeobox B9 Promotes Colon Cancer Progression by Targeting SRSF3.
Yuan L, Cheng F, Wu Z, Li X, Shen W. | 09/6/2023 |
| Activation of CTHRC1 by HOXB9 Promotes Angiogenesis through Fatty Acid Metabolism in Lung Adenocarcinoma. | Activation of CTHRC1 by HOXB9 Promotes Angiogenesis through Fatty Acid Metabolism in Lung Adenocarcinoma.
Liu K, Li X, Yang Z, Zhang R. | 05/30/2023 |
| HOXB9 a miR-122-5p regulated gene, suppressed the anticancer effects of brusatol by upregulating SCD1 expression in melanoma. | HOXB9 a miR-122-5p regulated gene, suppressed the anticancer effects of brusatol by upregulating SCD1 expression in melanoma.
Guo Z, Li N, Jiang Y, Zhang L, Tong L, Wang Y, Lv P, Li X, Han C, Lin J. | 05/19/2023 |
| Homeobox B9 Promotes the Progression of Hepatocellular Carcinoma via TGF-beta1/Smad and ERK1/2 Signaling Pathways. | Homeobox B9 Promotes the Progression of Hepatocellular Carcinoma via TGF-β1/Smad and ERK1/2 Signaling Pathways.
Bai L, Ge P, Zhang Y, Song Y, Xing R, Zhou D., Free PMC Article | 10/8/2022 |
| HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFbeta pathway in pancreatic cancer. | HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer.
Chiba N, Ochiai S, Gunji T, Kobayashi T, Sano T, Tomita K, Kawachi S., Free PMC Article | 10/1/2022 |
| HOXB9 blocks cell cycle progression to inhibit pancreatic cancer cell proliferation through the DNMT1/RBL2/c-Myc axis. | HOXB9 blocks cell cycle progression to inhibit pancreatic cancer cell proliferation through the DNMT1/RBL2/c-Myc axis.
Yao Y, Liu C, Wang B, Guan X, Fang L, Zhan F, Sun H, Li H, Lou C, Yan F, Lu X, Cui L, Liao Y, Han S, Yao Y, Zhang Y. | 04/30/2022 |
| HOXB9 Overexpression Promotes Colorectal Cancer Progression and Is Associated with Worse Survival in Liver Resection Patients for Colorectal Liver Metastases. | HOXB9 Overexpression Promotes Colorectal Cancer Progression and Is Associated with Worse Survival in Liver Resection Patients for Colorectal Liver Metastases.
Martinou E, Moller-Levet C, Karamanis D, Bagwan I, Angelidi AM., Free PMC Article | 03/26/2022 |
| Genome-Wide Epigenetic Landscape of Lung Adenocarcinoma Links HOXB9 DNA Methylation to Intrinsic EGFR-TKI Resistance and Heterogeneous Responses. | Genome-Wide Epigenetic Landscape of Lung Adenocarcinoma Links HOXB9 DNA Methylation to Intrinsic EGFR-TKI Resistance and Heterogeneous Responses.
Su SF, Liu CH, Cheng CL, Ho CC, Yang TY, Chen KC, Hsu KH, Tseng JS, Chen HW, Chang GC, Yu SL, Li KC., Free PMC Article | 03/26/2022 |
| A Systematic Review on HOX Genes as Potential Biomarkers in Colorectal Cancer: An Emerging Role of HOXB9. | A Systematic Review on HOX Genes as Potential Biomarkers in Colorectal Cancer: An Emerging Role of HOXB9.
Martinou E, Falgari G, Bagwan I, Angelidi AM., Free PMC Article | 01/15/2022 |
| WT1 regulates HOXB9 gene expression in a bidirectional way. | WT1 regulates HOXB9 gene expression in a bidirectional way.
Schmidt V, Sieckmann T, Kirschner KM, Scholz H. | 01/1/2022 |
| Insights into homeobox B9: a propeller for metastasis in dormant prostate cancer progenitor cells. | Insights into homeobox B9: a propeller for metastasis in dormant prostate cancer progenitor cells.
Sui Y, Hu W, Zhang W, Li D, Zhu H, You Q, Zhu R, Yi Q, Tang T, Gao L, Zhu S, Yang T., Free PMC Article | 12/18/2021 |
| HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier. | HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier.
Zheng H, Li C, Li Z, Zhu K, Bao H, Xiong J, Liang P., Free PMC Article | 08/7/2021 |
| HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours. | HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours.
Francis JC, Gardiner JR, Renaud Y, Chauhan R, Weinstein Y, Gomez-Sanchez C, Lefrançois-Martinez AM, Bertherat J, Val P, Swain A., Free PMC Article | 07/17/2021 |
| Mutually exclusive antiproliferative effect of cell line-specific HOX inhibition in epithelial ovarian cancer cell lines: SKOV-3 vs RMUG-S. | Mutually exclusive antiproliferative effect of cell line-specific HOX inhibition in epithelial ovarian cancer cell lines: SKOV-3 vs RMUG-S.
Kim M, Suh DH, Choi JY, Lee S, Bae JR, Kim K, No JH, Kim YB., Free PMC Article | 05/1/2021 |
| Homeobox B9 integrates bone morphogenic protein 4 with inflammation at atheroprone sites. | Homeobox B9 integrates bone morphogenic protein 4 with inflammation at atheroprone sites.
Souilhol C, Gauci I, Feng S, Tardajos Ayllon B, Mahmoud M, Canham L, Fragiadaki M, Serbanovic-Canic J, Ridger V, Evans PC., Free PMC Article | 02/13/2021 |
| Silencing of HOXB9 suppresses cellular proliferation, angiogenesis, migration and invasion of prostate cancer cells. | Silencing of HOXB9 suppresses cellular proliferation, angiogenesis, migration and invasion of prostate cancer cells.
Xu H, Wu S, Shen X, Wu D, Qin Z, Wang H, Chen X, Sun X. | 11/21/2020 |
| Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma. | Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma.
Sun X, Song J, Zhang J, Zhan J, Fang W, Zhang H. | 11/21/2020 |
| High HOXB9 expression is associated with invasion and metastasis of hepatocellular carcinoma by chaperoning LRP6. | GRP78 activates the Wnt/HOXB9 pathway to promote invasion and metastasis of hepatocellular carcinoma by chaperoning LRP6.
Xiong H, Xiao H, Luo C, Chen L, Liu X, Hu Z, Zou S, Guan J, Yang D, Wang K. | 06/20/2020 |
| HOXB9 promotes endometrial cancer progression by targeting E2F3. | HOXB9 promotes endometrial cancer progression by targeting E2F3.
Wan J, Liu H, Feng Q, Liu J, Ming L., Free PMC Article | 11/30/2019 |
| Results show the AcK27-HOXB9 level decreased in colon cancer patients and predicted better outcome. HOXB9 upregulated oncogenic EZH2 expression, whereas AcK27-HOXB9 suppressed it by translocating HOXB9 from nuclei into cytoplasm. AcK27-HOXB9 inhibits while non-acetylated HOXB9 promotes EZH2 expression and colon cancer progression. Thus, AcK27-HOXB9 underlies the tumor suppressive role of HOXB9. | HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression.
Song J, Wang T, Xu W, Wang P, Wan J, Wang Y, Zhan J, Zhang H. | 06/15/2019 |
| HOXB9 directly binds to the promoter of microRNA-765 and facilitates its transcription, which in turn targets FOXA2, resulting in a FOXA2 decrease and cancer stem cell increase. Elevated HOXB9 is found in human melanoma tissues, which is associated with microRNA-765 up-regulation and FOXA2 decreases. | Regulation of Cancer Stem Cell Self-Renewal by HOXB9 Antagonizes Endoplasmic Reticulum Stress-Induced Melanoma Cell Apoptosis via the miR-765-FOXA2 Axis.
Lin J, Zhang D, Fan Y, Chao Y, Chang J, Li N, Han L, Han C. | 05/25/2019 |
| These findings integrate the complexity of numerous mechanisms of anti-VEGF resistance into the single transcription factor HOXB9. Silencing HOXB9 could be a promising approach to modulate this resistance. Our results candidate HOXB9 as predictive biomarker for selecting colorectal cancer patients for antiangiogenic therapy | Homeobox B9 Mediates Resistance to Anti-VEGF Therapy in Colorectal Cancer Patients.
Carbone C, Piro G, Simionato F, Ligorio F, Cremolini C, Loupakis F, Alì G, Rossini D, Merz V, Santoro R, Zecchetto C, Zanotto M, Di Nicolantonio F, Bardelli A, Fontanini G, Tortora G, Melisi D. | 06/23/2018 |
| Study demonstrated that HOXB9 may facilitate hypertrophic scar formation via activating the mitogenactivated protein kinase signaling pathway. | Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen-activated protein kinase signaling pathway.
Xie Q, Liu D, Yu M, Wu X, Zhao Y, Hu Q, Wang Q., Free PMC Article | 05/5/2018 |