| Sequence variants in DLX5, HOXD13 and 445 kb-microduplication surrounding BTRC cause split-hand/foot malformation in three different families. | Sequence variants in DLX5, HOXD13 and 445 kb-microduplication surrounding BTRC cause split-hand/foot malformation in three different families.
Abdullah, Hussain S, Ji W, Khan H, Mis EK, Mushtaq R, Chodhary M, Raza MH, Jan A, Ullah I, Khokha MK, Lakhani SA, Ahmad W. | 01/3/2024 |
| HOXD13-associated synpolydactyly: Extending and validating the genotypic and phenotypic spectrum with 38 new and 49 published families. | HOXD13-associated synpolydactyly: Extending and validating the genotypic and phenotypic spectrum with 38 new and 49 published families.
Gottschalk A, Sczakiel HL, Hülsemann W, Schwartzmann S, Abad-Perez AT, Grünhagen J, Ott CE, Spielmann M, Horn D, Mundlos S, Jamsheer A, Mensah MA. | 11/13/2023 |
| Variants Identified in the HOXC13 and HOXD13 Genes Suggest Association with Cervical Cancer in a Cohort of Mexican Women. | Variants Identified in the HOXC13 and HOXD13 Genes Suggest Association with Cervical Cancer in a Cohort of Mexican Women.
Juárez-Rendón KJ, Castro-García MA, Prada-Ortega DG, Rivera G, Ruíz-Godoy LM, Enríquez-Cárcamo VI, Reyes-Lopez MA., Free PMC Article | 03/2/2023 |
| EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma. | EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.
Apfelbaum AA, Wu F, Hawkins AG, Magnuson B, Jiménez JA, Taylor SD, Wrenn ED, Waltner O, Pfaltzgraff ER, Song JY, Hall C, Wellik DM, Ljungman M, Furlan SN, Ryan RJH, Sarthy JF, Lawlor ER., Free PMC Article | 10/22/2022 |
| Identification of a HOXD13 variant in a Mongolian family with incomplete penetrance syndactyly by exon sequencing. | Identification of a HOXD13 variant in a Mongolian family with incomplete penetrance syndactyly by exon sequencing.
Husile H, Wu Z, Yang L, Cao Y, Wu Q., Free PMC Article | 10/8/2022 |
| Novel HOXD13 variants in syndactyly type 1b and type 1c, and a new spectrum of TP63-related disorders. | Novel HOXD13 variants in syndactyly type 1b and type 1c, and a new spectrum of TP63-related disorders.
Patel R, Singh SK, Bhattacharya V, Ali A. | 05/21/2022 |
| Long-read whole genome sequencing reveals HOXD13 alterations in synpolydactyly. | Long-read whole genome sequencing reveals HOXD13 alterations in synpolydactyly.
Melas M, Kautto EA, Franklin SJ, Mori M, McBride KL, Mosher TM, Pfau RB, Hernandez-Gonzalez ME, McGrath SD, Magrini VJ, White P, Samora JB, Koboldt DC, Wilson RK. | 05/7/2022 |
| A novel microdeletion upstream of HOXD13 in a Chinese family with synpolydactyly. | A novel microdeletion upstream of HOXD13 in a Chinese family with synpolydactyly.
Jia W, Zhou X, Guo N, Zhang D, Hou M, Luo Y, Peng X, Yang X, Zhang X. | 04/16/2022 |
| Nonframeshifting indel variations in polyalanine repeat of HOXD13 gene underlies hereditary limb malformation for two Chinese families. | Nonframeshifting indel variations in polyalanine repeat of HOXD13 gene underlies hereditary limb malformation for two Chinese families.
Zu B, Wang Z, Xu Y, You G, Fu Q. | 04/9/2022 |
| HOXD13 promotes the malignant progression of colon cancer by upregulating PTPRN2. | HOXD13 promotes the malignant progression of colon cancer by upregulating PTPRN2.
Yin J, Guo Y., Free PMC Article | 02/19/2022 |
| Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL. | Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL.
Goldberg L, Negi V, Chung YJ, Onozawa M, Zhu YJ, Walker RL, Pierce R, Patel DP, Krausz KW, Gonzalez FJ, Goodell MA, Rodriguez BAT, Meltzer PS, Aplan PD., Free PMC Article | 01/8/2022 |
| A novel miR-7156-3p-HOXD13 axis modulates glioma progression by regulating tumor cell stemness. | A novel miR-7156-3p-HOXD13 axis modulates glioma progression by regulating tumor cell stemness.
Zhang J, Deng M, Tong H, Xue W, Guo Y, Wang J, Chen L, Wang S., Free PMC Article | 11/13/2021 |
| HOXD13 suppresses prostate cancer metastasis and BMP4-induced epithelial-mesenchymal transition by inhibiting SMAD1. | HOXD13 suppresses prostate cancer metastasis and BMP4-induced epithelial-mesenchymal transition by inhibiting SMAD1.
Xu F, Shangguan X, Pan J, Yue Z, Shen K, Ji Y, Zhang W, Zhu Y, Sha J, Wang Y, Fan L, Dong B, Wang Q, Xue W. | 09/11/2021 |
| Genome sequencing in families with congenital limb malformations. | Genome sequencing in families with congenital limb malformations.
Elsner J, Mensah MA, Holtgrewe M, Hertzberg J, Bigoni S, Busche A, Coutelier M, de Silva DC, Elçioglu N, Filges I, Gerkes E, Girisha KM, Graul-Neumann L, Jamsheer A, Krawitz P, Kurth I, Markus S, Megarbane A, Reis A, Reuter MS, Svoboda D, Teller C, Tuysuz B, Türkmen S, Wilson M, Woitschach R, Vater I, Caliebe A, Hülsemann W, Horn D, Mundlos S, Spielmann M., Free PMC Article | 07/17/2021 |
| GALNT10 promotes the proliferation and metastatic ability of gastric cancer and reduces 5-fluorouracil sensitivity by activating HOXD13. | GALNT10 promotes the proliferation and metastatic ability of gastric cancer and reduces 5-fluorouracil sensitivity by activating HOXD13.
Xu G, Wu YL, Li N, Xu R, Zhang JB, Ming H, Zhang Y. | 07/3/2021 |
| Brachydactyly type A3 is caused by a novel 13 bp HOXD13 frameshift deletion in a Chinese family. | Brachydactyly type A3 is caused by a novel 13 bp HOXD13 frameshift deletion in a Chinese family.
Zhang M, Lu L, Wei B, Zhang Y, Li X, Shi Y, Ge W, Sun M. | 06/5/2021 |
| a heterozygous nonsense mutation in the HOXD13 gene was newly identified in two patients with mild phenotypes of synpolydactyly. | A Nonsense Mutation in HOXD13 Gene from A Chinese Family with Non-Syndromic Synpolydactyly.
Guo X, Shi T, Lin M, Zhang Y. | 03/21/2020 |
| this study revealed that HOXB9, HOXB13, and HOXD13 were upregulated and may play important roles in laryngeal squamous cell carcinoma (LSCC). Moreover, HOXB9 may serve as a novel marker of poor prognosis and a potential therapeutic target in LSCC patients. | HOXB9 Expression Correlates with Histological Grade and Prognosis in LSCC.
Sun C, Han C, Wang P, Jin Y, Sun Y, Qu L., Free PMC Article | 04/28/2018 |
| The results suggest that the c.917G>A (p.R306Q) mutation in the HOXD13 gene, may be responsible for syndactyly type Ic in this family. | Identification of a missense HOXD13 mutation in a Chinese family with syndactyly type I-c using exome sequencing.
Deng H, Tan T, He Q, Lin Q, Yang Z, Zhu A, Guan L, Xiao J, Song Z, Guo Y. | 03/31/2018 |
| Knock down of the dickkopf WNT signaling pathway inhibitor 2 (DKK2) resulted in a significant suppression of HOXD10, HOXD11 and HOXD13 while over-expression of DKK2 and stimulation with factors of the WNT signaling pathway. | The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma.
von Heyking K, Roth L, Ertl M, Schmidt O, Calzada-Wack J, Neff F, Lawlor ER, Burdach S, Richter GH., Free PMC Article | 01/20/2018 |
| a novel mutation causing truncation of HOXD13 protein was successfully identified as being associated with an atypical non-syndromic SPD phenotype in our study. | Exome sequencing identifies a novel nonsense mutation of HOXD13 in a Chinese family with synpolydactyly.
Wang B, Li N, Geng J, Wang Z, Fu Q, Wang J, Xu Y. | 02/18/2017 |
| down-regulation of HOXD13 might be a potentially useful prognostic marker for patients with breast cancer. | Prognostic significance of HOXD13 expression in human breast cancer.
Zhong ZB, Shan M, Qian C, Liu T, Shi QY, Wang J, Liu Y, Liu Y, Huang YX, Pang D., Free PMC Article | 12/17/2016 |
| A homozygous HOXD13 missense mutation causes a severe form of synpolydactyly with metacarpal to carpal transformation. | A homozygous HOXD13 missense mutation causes a severe form of synpolydactyly with metacarpal to carpal transformation.
Ibrahim DM, Tayebi N, Knaus A, Stiege AC, Sahebzamani A, Hecht J, Mundlos S, Spielmann M. | 12/17/2016 |
| HOXD13 methylation is a common event in primary breast cancer and is associated with poor survival of breast cancer patients. | HOXD13 methylation status is a prognostic indicator in breast cancer.
Zhong Z, Shan M, Wang J, Liu T, Xia B, Niu M, Ren Y, Pang D., Free PMC Article | 10/1/2016 |
| A 27 bp expansion mutation in exon 1 of HOXD13 was associated with autosomal dominant synpolydactyly in a Chinese family. | [Mutation analysis of HOXD13 gene in a Chinese family affected with autosomal dominant synpolydactyly].
Li Y, Xin Q, Shan S, Li J, Liu Q. | 11/21/2015 |