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    HSPA8 heat shock protein family A (Hsp70) member 8 [ Homo sapiens (human) ]

    Gene ID: 3312, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    HSPA8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation.

    HSPA8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation.
    Rafiq S, Mungure I, Banz Y, Niklaus NJ, Kaufmann T, Müller S, Jacquel A, Robert G, Auberger P, Torbett BE, Muller S, Tschan MP, Humbert M.

    07/23/2024
    Experimental and computational investigation of the effect of Hsc70 structural variants on inhibiting amylin aggregation.

    Experimental and computational investigation of the effect of Hsc70 structural variants on inhibiting amylin aggregation.
    Chaari A, Saikia N, Paul P, Yousef M, Ding F, Ladjimi M.

    05/6/2024
    Heat shock protein family A member 8 is a prognostic marker for bladder cancer: Evidences based on experiments and machine learning.

    Heat shock protein family A member 8 is a prognostic marker for bladder cancer: Evidences based on experiments and machine learning.
    Liu Y, Pang ZQ, Wang JS, Wang JF, He JX, Ji B, Zhang L, Ren MH., Free PMC Article

    04/12/2024
    Plasmodium falciparum J-dot localized J domain protein A8iJp modulates the chaperone activity of human HSPA8.

    Plasmodium falciparum J-dot localized J domain protein A8iJp modulates the chaperone activity of human HSPA8.
    Sahu W, Bai T, Das A, Mukherjee S, Prusty A, Mallick NR, Elangovan S, Reddy KS.

    04/12/2024
    HSPA8-mediated stability of the CLPP protein regulates mitochondrial autophagy in cisplatin-resistant ovarian cancer cells.

    HSPA8-mediated stability of the CLPP protein regulates mitochondrial autophagy in cisplatin-resistant ovarian cancer cells.
    Kou X, Yang X, Zhao Z, Li L., Free PMC Article

    04/5/2024
    RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination.

    RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination.
    Zhang C, Wang Y, Wu G, Sun N, Bai H, Li X, Han S, Zhou H, Qi R, Zhang J., Free PMC Article

    03/8/2024
    Hemin competitively inhibits HSPA8 ATPase activity mitigating its foldase function.

    Hemin competitively inhibits HSPA8 ATPase activity mitigating its foldase function.
    Pandey AK, Trivedi V.

    02/4/2024
    Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression.

    Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression.
    Deng W, Ai J, Zhang W, Zhou Z, Li M, Yan L, Zhang L, Huang Z, Wu Z, Ai J, Jiang H., Free PMC Article

    09/25/2023
    The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70.

    The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70.
    Velasco-Carneros L, Cuéllar J, Dublang L, Santiago C, Maréchal JD, Martín-Benito J, Maestro M, Fernández-Higuero JÁ, Orozco N, Moro F, Valpuesta JM, Muga A., Free PMC Article

    09/11/2023
    Association between HSPA8 Gene Variants and Ischemic Stroke: A Pilot Study Providing Additional Evidence for the Role of Heat Shock Proteins in Disease Pathogenesis.

    Association between HSPA8 Gene Variants and Ischemic Stroke: A Pilot Study Providing Additional Evidence for the Role of Heat Shock Proteins in Disease Pathogenesis.
    Kobzeva KA, Soldatova MO, Stetskaya TA, Soldatov VO, Deykin AV, Freidin MB, Bykanova MA, Churnosov MI, Polonikov AV, Bushueva OY., Free PMC Article

    06/30/2023
    ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells.

    ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells.
    Sanchez-Briñas A, Duran-Ruiz C, Astola A, Arroyo MM, Raposo FG, Valle A, Bolivar J., Free PMC Article

    06/1/2023
    LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion.

    LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion.
    Jung-Garcia Y, Maiques O, Monger J, Rodriguez-Hernandez I, Fanshawe B, Domart MC, Renshaw MJ, Marti RM, Matias-Guiu X, Collinson LM, Sanz-Moreno V, Carlton JG., Free PMC Article

    02/4/2023
    HSPA8 Is a New Biomarker of Triple Negative Breast Cancer Related to Prognosis and Immune Infiltration.

    HSPA8 Is a New Biomarker of Triple Negative Breast Cancer Related to Prognosis and Immune Infiltration.
    Ying B, Xu W, Nie Y, Li Y., Free PMC Article

    01/7/2023
    HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease.

    HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease.
    Dong Y, Li T, Ma Z, Zhou C, Wang X, Li J., Free PMC Article

    10/29/2022
    HSPA8 Single-Nucleotide Polymorphism Is Associated with Serum HSC70 Concentration and Carotid Artery Atherosclerosis in Nonalcoholic Fatty Liver Disease.

    HSPA8 Single-Nucleotide Polymorphism Is Associated with Serum HSC70 Concentration and Carotid Artery Atherosclerosis in Nonalcoholic Fatty Liver Disease.
    Zhao W, Mori H, Tomiga Y, Tanaka K, Perveen R, Mine K, Inadomi C, Yoshioka W, Kubotsu Y, Isoda H, Kuwashiro T, Oeda S, Akiyama T, Zhao Y, Ozaki I, Nagafuchi S, Kawaguchi A, Aishima S, Anzai K, Takahashi H., Free PMC Article

    08/6/2022
    Long noncoding RNA MAGI2-AS3 regulates the H2O2 level and cell senescence via HSPA8.

    Long noncoding RNA MAGI2-AS3 regulates the H(2)O(2) level and cell senescence via HSPA8.
    Zhang Y, Qiao X, Liu L, Han W, Liu Q, Wang Y, Xie T, Tang Y, Wang T, Meng J, Ye A, He S, Chen R, Chen C., Free PMC Article

    07/16/2022
    Inhibition of HSC70 alleviates hypertrophic cardiomyopathy pathology in human induced pluripotent stem cell-derived cardiomyocytes with a MYBPC3 mutation.

    Inhibition of HSC70 alleviates hypertrophic cardiomyopathy pathology in human induced pluripotent stem cell-derived cardiomyocytes with a MYBPC3 mutation.
    Qiu H, Sun Y, Pan Z, Zhou J, Wang H, Wang X, Cai D, Fu G, Gong T, Jiang C, Liang P., Free PMC Article

    05/21/2022
    An association study of the HSPA8 gene polymorphisms with schizophrenia in a Polish population.

    An association study of the HSPA8 gene polymorphisms with schizophrenia in a Polish population.
    Kowalczyk M, Owczarek A, Suchanek-Raif R, Kucia K, Kowalski J., Free PMC Article

    05/14/2022
    HSPA8 Is Identified as a Novel Regulator of Hypertensive Disorders in Pregnancy by Modulating the beta-Arrestin1/A1AR Axis.

    HSPA8 Is Identified as a Novel Regulator of Hypertensive Disorders in Pregnancy by Modulating the β-Arrestin1/A1AR Axis.
    Zhang K, Zhang H, Wang F, Gao S, Sun C.

    03/26/2022
    Heat Shock Protein Member 8 (HSPA8) Is Involved in Porcine Reproductive and Respiratory Syndrome Virus Attachment and Internalization.

    Heat Shock Protein Member 8 (HSPA8) Is Involved in Porcine Reproductive and Respiratory Syndrome Virus Attachment and Internalization.
    Wang L, Li R, Geng R, Zhang L, Chen XX, Qiao S, Zhang G., Free PMC Article

    03/19/2022
    FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression.

    FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression.
    Malikov V, Meade N, Simons LM, Hultquist JF, Naghavi MH., Free PMC Article

    03/5/2022
    Hspa8 and ICAM-1 as damage-induced mediators of gammadelta T cell activation.

    Hspa8 and ICAM-1 as damage-induced mediators of γδ T cell activation.
    Johnson MD, Otuki MF, Cabrini DA, Rudolph R, Witherden DA, Havran WL.

    02/12/2022
    Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B.

    Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B.
    Jaimon E, Tripathi A, Khurana A, Ghosh D, Sugatha J, Datta S., Free PMC Article

    01/29/2022
    Structural, thermodynamic and functional studies of human 71 kDa heat shock cognate protein (HSPA8/hHsc70).

    Structural, thermodynamic and functional studies of human 71 kDa heat shock cognate protein (HSPA8/hHsc70).
    Silva NSM, Rodrigues LFC, Dores-Silva PR, Montanari CA, Ramos CHI, Barbosa LRS, Borges JC.

    01/1/2022
    Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy.

    Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy.
    Losmanova T, Zens P, Scherz A, Schmid RA, Tschan MP, Berezowska S., Free PMC Article

    12/4/2021
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