| GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia. | GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia.
Chen X, Wu Q, Gong W, Ju S, Fan J, Gao X, Liu X, Lei X, Liu S, Ming X, Wang Q, Fu M, Song Y, Wang Y, Zhan Q., Free PMC Article | 10/1/2024 |
| Tumor suppressor KEAP1 promotes HSPA9 degradation, controlling mitochondrial biogenesis in breast cancer. | Tumor suppressor KEAP1 promotes HSPA9 degradation, controlling mitochondrial biogenesis in breast cancer.
Han B, Zhen F, Sun Y, Sun B, Wang HY, Liu W, Huang J, Liang X, Wang YR, Chen XS, Li SJ, Hu J. | 07/31/2024 |
| Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks. | Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks.
Chen W, Song YS, Lee HS, Lin CW, Lee J, Kang YE, Kim SK, Kim SY, Park YJ, Park JI. | 07/30/2024 |
| HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells. | HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells.
Butler C, Dunmire M, Choi J, Szalai G, Johnson A, Lei W, Chen X, Liu L, Li W, Walter MJ, Liu T., Free PMC Article | 05/3/2024 |
| OMA1 competitively binds to HSPA9 to promote mitophagy and activate the cGAS-STING pathway to mediate GBM immune escape. | OMA1 competitively binds to HSPA9 to promote mitophagy and activate the cGAS-STING pathway to mediate GBM immune escape.
Zhu W, Rao J, Zhang LH, Xue KM, Li L, Li JJ, Chen QZ, Fu R., Free PMC Article | 04/30/2024 |
| METTL3-mediated HSPA9 m6A modification promotes malignant transformation and inhibits cellular senescence by regulating exosomal mortalin protein in cervical cancer. | METTL3-mediated HSPA9 m6A modification promotes malignant transformation and inhibits cellular senescence by regulating exosomal mortalin protein in cervical cancer.
Ao K, Yin M, Lyu X, Xiao Y, Chen X, Zhong S, Wen X, Yuan J, Ye M, Zhang J, Li X, Hao Y, Guo X. | 03/26/2024 |
| Prenatal to preimplantation genetic diagnosis of a novel compound heterozygous mutation in HSPA9 associated with Even-Plus syndrome. | Prenatal to preimplantation genetic diagnosis of a novel compound heterozygous mutation in HSPA9 associated with Even-Plus syndrome.
Chang X, Ji C, Zhang T, Huang H. | 02/27/2024 |
| Clinical Relevance of Mortalin in Ovarian Cancer Patients. | Clinical Relevance of Mortalin in Ovarian Cancer Patients.
Rajtak A, Czerwonka A, Pitter M, Kotarski J, Okła K., Free PMC Article | 10/26/2023 |
| The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway. | The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway.
Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T., Free PMC Article | 08/31/2023 |
| Effect of Mortalin on Scar Formation in Human Dermal Fibroblasts and a Rat Incisional Scar Model. | Effect of Mortalin on Scar Formation in Human Dermal Fibroblasts and a Rat Incisional Scar Model.
Jung BK, Roh TS, Roh H, Lee JH, Yun CO, Lee WJ., Free PMC Article | 08/6/2022 |
| GRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients. | GRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients.
Li J, Qi F, Su H, Zhang C, Zhang Q, Chen Y, Chen P, Su L, Chen Y, Yang Y, Chen Z, Zhang S., Free PMC Article | 05/14/2022 |
| Immunoexpression of HSPA9 and CUL2 in prostatic tissue and adenocarcinoma. | Immunoexpression of HSPA9 and CUL2 in prostatic tissue and adenocarcinoma.
Hirth CG, Vasconcelos GR, da Cunha MDPSS, Leite CHB, Dornelas CA. | 03/26/2022 |
| Expressions of HSPA1L and HSPA9 are associated with poor sperm quality of low-motility spermatozoa in fertile men. | Expressions of HSPA1L and HSPA9 are associated with poor sperm quality of low-motility spermatozoa in fertile men.
Liu X, Teng Z, Wang Z, Zhu P, Song Z, Liu F. | 02/19/2022 |
| HSP70s in Breast Cancer: Promoters of Tumorigenesis and Potential Targets/Tools for Therapy. | HSP70s in Breast Cancer: Promoters of Tumorigenesis and Potential Targets/Tools for Therapy.
Kabakov AE, Gabai VL., Free PMC Article | 01/22/2022 |
| Loss and gain of function of Grp75 or mitofusin 2 distinctly alter cholesterol metabolism, but all promote triglyceride accumulation in hepatocytes. | Loss and gain of function of Grp75 or mitofusin 2 distinctly alter cholesterol metabolism, but all promote triglyceride accumulation in hepatocytes.
Bassot A, Prip-Buus C, Alves A, Berdeaux O, Perrier J, Lenoir V, Ji-Cao J, Berger MA, Loizon E, Cabaret S, Panthu B, Rieusset J, Morio B. | 01/8/2022 |
| GRP75-mediated upregulation of HMGA1 stimulates stage I lung adenocarcinoma progression by activating JNK/c-JUN signaling. | GRP75-mediated upregulation of HMGA1 stimulates stage I lung adenocarcinoma progression by activating JNK/c-JUN signaling.
Qiao GB, Wang RT, Wang SN, Tao SL, Tan QY, Jin H., Free PMC Article | 12/25/2021 |
| A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance. | A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance.
Liao Y, Liu Y, Shao Z, Xia X, Deng Y, Cai J, Yao L, He J, Yu C, Hu T, Sun W, Liu F, Tang D, Liu J, Huang H. | 12/25/2021 |
| Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. | Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability.
Wu PK, Hong SK, Chen W, Becker AE, Gundry RL, Lin CW, Shao H, Gestwicki JE, Park JI., Free PMC Article | 11/6/2021 |
| Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy. | Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy.
Jo DS, Park SJ, Kim AK, Park NY, Kim JB, Bae JE, Park HJ, Shin JH, Chang JW, Kim PK, Jung YK, Koh JY, Choe SK, Lee KS, Cho DH., Free PMC Article | 09/4/2021 |
| Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-Raf(V600E) melanoma cells. | Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-Raf(V600E) melanoma cells.
Wu PK, Hong SK, Park JI., Free PMC Article | 08/7/2021 |
| Novel role of mortalin in attenuating HIV-1 Tat-mediated astrogliosis. | Novel role of mortalin in attenuating HIV-1 Tat-mediated astrogliosis.
Priyanka, Wadhwa R, Chaudhuri R, Nag TC, Seth P., Free PMC Article | 07/24/2021 |
| Mortalin contributes to colorectal cancer by promoting proliferation and epithelial-mesenchymal transition. | Mortalin contributes to colorectal cancer by promoting proliferation and epithelial-mesenchymal transition.
Xu M, Zhang Y, Cui M, Wang X, Lin Z. | 06/26/2021 |
| Mortalin peptides exert antitumor activities and act as adjuvants to antibody-mediated complement-dependent cytotoxicity. | Mortalin peptides exert antitumor activities and act as adjuvants to antibody-mediated complement-dependent cytotoxicity.
Jubran R, Saar-Ray M, Wawruszak A, Ziporen L, Donin N, Bairey O, Fishelson Z. | 06/19/2021 |
| Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA. | Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA.
Kang M, Tang B, Li J, Zhou Z, Liu K, Wang R, Jiang Z, Bi F, Patrick D, Kim D, Mitra AK, Yang-Hartwich Y., Free PMC Article | 06/12/2021 |
| Mortalin promotes breast cancer malignancy. | Mortalin promotes breast cancer malignancy.
Zhang R, Meng Z, Wu X, Zhang M, Zhang S, Jin T. | 05/1/2021 |