| Increased mRNA expression for serotonin receptor 1B (HTR1B) is associated with thrombosis in BCR::ABL1-negative myeloproliferative neoplasms. | Increased mRNA expression for serotonin receptor 1B (HTR1B) is associated with thrombosis in BCR::ABL1-negative myeloproliferative neoplasms.
Gurban P, Mambet C, Botezatu A, Necula LG, Matei L, Neagu AI, Pitica IM, Dragu LD, Nastasie Schulman A, Ataman M, Nedeianu S, Chivu-Economescu M, Bleotu C, Anton G, Diaconu CC., Free PMC Article | 08/31/2024 |
| Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia. | Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia.
Fernández-de-Las-Peñas C, Ambite-Quesada S, Fernández-Méndez LM, Jiménez-Antona C, Gómez-Calero C, Pocinho R, Valera-Calero JA, Cigarán-Méndez M, Arendt-Nielsen L., Free PMC Article | 08/23/2024 |
| The rs6296 polymorphism in the 5-HT1b receptor in Dutch men with lifelong premature ejaculation: a genetic case-control association study. | The rs6296 polymorphism in the 5-HT1b receptor in Dutch men with lifelong premature ejaculation: a genetic case-control association study.
van Raaij JJ, Janssen PKC. | 07/1/2024 |
| Synergistic Interaction of 5-HT1B and 5-HT2B Receptors in Cytoplasmic Ca[2+] Regulation in Human Umbilical Vein Endothelial Cells: Possible Involvement in Pathologies. | Synergistic Interaction of 5-HT(1B) and 5-HT(2B) Receptors in Cytoplasmic Ca(2+) Regulation in Human Umbilical Vein Endothelial Cells: Possible Involvement in Pathologies.
Rybakova EY, Avdonin PP, Trufanov SK, Goncharov NV, Avdonin PV., Free PMC Article | 09/30/2023 |
| HTR1B genotype and psychopathy: Main effect and interaction with paternal maltreatment. | HTR1B genotype and psychopathy: Main effect and interaction with paternal maltreatment.
Palumbo S, Mariotti V, Vellucci S, Antonelli K, Anderson N, Harenski C, Pietrini P, Kiehl KA, Pellegrini S. | 09/17/2022 |
| Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder. | Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder.
Li Y, Lu Y, Xie Q, Zeng X, Zhang R, Dang W, Zhu Y, Zhang J. | 07/23/2022 |
| Effects of HTR1B 3' region polymorphisms and functional regions on gene expression regulation. | Effects of HTR1B 3' region polymorphisms and functional regions on gene expression regulation.
Xia X, Ding M, Xuan JF, Xing JX, Pang H, Yao J, Wu X, Wang BJ., Free PMC Article | 04/3/2021 |
| First Evidence of Kv3.1b Potassium Channel Subtype Expression during Neuronal Serotonergic 1C11 Cell Line Development. | First Evidence of Kv3.1b Potassium Channel Subtype Expression during Neuronal Serotonergic 1C11 Cell Line Development.
Tabka H, Cheikh A, Maatoug S, Ayeb ME, Bendahhou S, Benkhalifa R., Free PMC Article | 03/6/2021 |
| Functional polymorphisms and transcriptional analysis in the 5' region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disorders. | Functional polymorphisms and transcriptional analysis in the 5' region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disorders.
Xia X, Ding M, Xuan JF, Xing JX, Yao J, Wu X, Wang BJ., Free PMC Article | 02/13/2021 |
| Serotonin system genes and hoarding with and without other obsessive-compulsive traits in a population-based, pediatric sample: A genetic association study. | Serotonin system genes and hoarding with and without other obsessive-compulsive traits in a population-based, pediatric sample: A genetic association study.
Sinopoli VM, Erdman L, Burton CL, Park LS, Dupuis A, Shan J, Goodale T, Shaheen SM, Crosbie J, Schachar RJ, Arnold PD. | 01/9/2021 |
| The discovery of a new antibody for BRIL-fused GPCR structure determination. | The discovery of a new antibody for BRIL-fused GPCR structure determination.
Miyagi H, Asada H, Suzuki M, Takahashi Y, Yasunaga M, Suno C, Iwata S, Saito JI., Free PMC Article | 12/12/2020 |
| [The role of genetic factors in the development of suicidal behavior in individuals with dependence on synthetic cathinones].", trans "Rol' geneticheskikh faktorov v razvitii suitsidal'nogo povedeniya u lits s zavisimost'yu ot sinteticheskikh katinonov. | [The role of genetic factors in the development of suicidal behavior in individuals with dependence on synthetic cathinones].
Gareeva AE, Badretdinov UG, Akhmetova EA, Kinyasheva KO, Nasibullin TR, Samigullina LI, Timerbulatov IF, Timerbulatova MF, Asadullin AR. | 12/5/2020 |
| This study uses over 25mus of unbiased atomistic molecular dynamics simulations to identify cholesterol interaction sites in the 5-HT1B and 5-HT2B receptors and evaluate their impact on receptor structure. | Influence of Cholesterol and Its Stereoisomers on Members of the Serotonin Receptor Family.
Oakes V, Domene C. | 03/28/2020 |
| Regulation of heterologously expressed 5-HT1B receptors coupling to potassium channels in AtT-20 cells | Regulation of heterologously expressed 5-HT(1B) receptors coupling to potassium channels in AtT-20 cells.
Heblinski M, Bladen C, Connor M., Free PMC Article | 02/29/2020 |
| The down-regulation effects of IFN-alpha on p11, 5-HT1b and 5-HT4 were associated with the lysosome and ubiquitin-proteasome-mediated pathways. p11 was identified as a potent regulator to modulate the ubiquitination of 5-HT1b and 5-HT4. Therefore, it could be potential target therapies in IFN-ainduced depression | Down-regulation effects of IFN-α on p11, 5-htr1b and 5-HTR4 protein levels were affected by NH(4)CL or MG132 treatment in SH-sy5y cells.
Guo J, Ding H, Lv Z, Jiao J, Wang H, Ji Y. | 02/1/2020 |
| HTR1B polymorphisms are associated with schizophrenia in the northern Han Chinese population, which provides an etiological reference for schizophrenia. | Polymorphisms in the human serotonin receptor 1B (HTR1B) gene are associated with schizophrenia: a case control study.
Xia X, Ding M, Xuan JF, Xing JX, Pang H, Wang BJ, Yao J., Free PMC Article | 09/21/2019 |
| Our work suggests that the studied polymorphisms, 5HT1A (rs6295), 5HT1B (rs6296), and 5HT2C (rs6318), were not related to the presence of temporal lobe epilepsy (TLE), psychiatric comorbidities in TLE, and epilepsy-related factors. | Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis.
Vincentiis S, Alcantara J, Rzezak P, S Kerr D, F Gattaz W, van der Linden H Jr, Dos Santos B, Melo-Souza SE, Arruda F, Ragazzo P, Chaim-Avancini T, H Serpa M, Fernandes F, Moreno RA, Busatto G, Alessi R, Demarque R, D Valente K. | 03/2/2019 |
| We report here for the first time that migraine patients have low 5-HT1B receptor binding in pain modulating regions | Low 5-HT(1B) receptor binding in the migraine brain: A PET study.
Deen M, Hansen HD, Hougaard A, da Cunha-Bang S, Nørgaard M, Svarer C, Keller SH, Thomsen C, Ashina M, Knudsen GM. | 02/2/2019 |
| cryo-electron microscopy structure of the serotonin 5-HT1B receptor (5-HT1BR) bound to the agonist donitriptan and coupled to an engineered Go heterotrimer | Cryo-EM structure of the serotonin 5-HT(1B) receptor coupled to heterotrimeric G(o).
García-Nafría J, Nehmé R, Edwards PC, Tate CG., Free PMC Article | 01/19/2019 |
| The results suggest that HTR1A/1B DNA hypomethylation and its interaction with recent life stress might drive impaired antidepressant treatment response. Meanwhile, DNA methylation, in turn, was modified by antidepressant treatment and environments. | HTR1A/1B DNA methylation may predict escitalopram treatment response in depressed Chinese Han patients.
Wang P, Lv Q, Mao Y, Zhang C, Bao C, Sun H, Chen H, Yi Z, Cai W, Fang Y. | 09/1/2018 |
| Involvement of HTR1B variants in ADHD susceptibility as well as in externalizing and internalizing comorbidities, considering sex differences. | Evidence of sexual dimorphism of HTR1B gene on major adult ADHD comorbidities.
Müller D, Grevet EH, Panzenhagen AC, Cupertino RB, da Silva BS, Kappel DB, Mota NR, Blaya-Rocha P, Teche SP, Vitola ES, Rohde LA, Contini V, Rovaris DL, Schuch JB, Bau CHD. | 06/9/2018 |
| The polymorphism of HTR1B C861G is not a risk factor for Tourette's in Han Chinese population. | Association between the polymorphism of C861G (rs6296) in the serotonin 1B receptor gene and Tourette syndrome in Han Chinese people.
Yi M, Zhang Y, Wang Y, Su N, Liu S. | 02/24/2018 |
| Acute tryptophan depletion (ATD) did not significantly influence participants' sensitivity to probability, wins, or losses, although there was a trend for a lower tendency to choose experimental gambles overall following depletion. Following ATD, participants with higher peripheral 5-HT1B transcription levels increased choice of experimental gambles and used information pertaining to possible wins more when making choices | Peripheral Serotonin 1B Receptor Transcription Predicts the Effect of Acute Tryptophan Depletion on Risky Decision-Making.
Faulkner P, Mancinelli F, Lockwood PL, Matarin M, Dolan RJ, Wood NW, Dayan P, Roiser JP., Free PMC Article | 02/17/2018 |
| This study found several promoter variants in linkage disequilibrium that may potentially influence the allelic imbalance in the C861G variant. aAnd no evidence of allelic imbalance nor parent-of-origin effects of the C861G variant was observed in suicidal behavior. | Differential Allelic Expression of HTR1B in Suicide Victims: Genetic and Epigenetic Effect of the Cis-Acting Variants.
Bani-Fatemi A, Howe A, Zai C, Kennedy JL, Vincent J, Strauss J, Wong A, De Luca V. | 02/10/2018 |
| Single nucleotide polymorphism in HTR1B gene is associated with Attention deficit hyperactivity disorder. | Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability.
Bidwell LC, Gray JC, Weafer J, Palmer AA, de Wit H, MacKillop J., Free PMC Article | 02/10/2018 |