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    HTR2A 5-hydroxytryptamine receptor 2A [ Homo sapiens (human) ]

    Gene ID: 3356, updated on 10-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits.

    G protein-specific mechanisms in the serotonin 5-HT(2A) receptor regulate psychosis-related effects and memory deficits.
    Kossatz E, Diez-Alarcia R, Gaitonde SA, Ramon-Duaso C, Stepniewski TM, Aranda-Garcia D, Muneta-Arrate I, Tepaz E, Saen-Oon S, Soliva R, Shahraki A, Moreira D, Brea J, Loza MI, de la Torre R, Kolb P, Bouvier M, Meana JJ, Robledo P, Selent J., Free PMC Article

    06/6/2024
    The Association Between the 5-Hydroxytryptamine Receptor 2A Gene Variants rs6311 and rs6313 and Obstructive Sleep Apnea in the Iranian Kurdish Population.

    The Association Between the 5-Hydroxytryptamine Receptor 2A Gene Variants rs6311 and rs6313 and Obstructive Sleep Apnea in the Iranian Kurdish Population.
    Abdolsamadi M, Rasouli S, Alizadeh Severi A, Khirehgesh MR, Safari F, Mahdieh N, Khazaie H, Soleymani B, Akbari B.

    05/3/2024
    Fibroblast expression of neurotransmitter receptor HTR2A associates with inflammation in rheumatoid arthritis joint.

    Fibroblast expression of neurotransmitter receptor HTR2A associates with inflammation in rheumatoid arthritis joint.
    Xiang C, Hong SM, Zhao B, Pi H, Du F, Lu X, Tang Y, Shen N, Yang C, Wang R., Free PMC Article

    05/2/2024
    Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students.

    Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students.
    Kashina YV, Cherednik IL, Pokrovsky VM, Polishchuk SV.

    04/24/2024
    Interaction between HTR2A rs3125 and negative life events in suicide attempts among patients with major depressive disorder: a cross-sectional study.

    Interaction between HTR2A rs3125 and negative life events in suicide attempts among patients with major depressive disorder: a cross-sectional study.
    Pang JY, Wang YP, Teng HM, He J, Luo R, Feng SM, Yue WH, Li HF., Free PMC Article

    04/5/2024
    A role for the serotonin 2A receptor in the expansion and functioning of human transmodal cortex.

    A role for the serotonin 2A receptor in the expansion and functioning of human transmodal cortex.
    Luppi AI, Girn M, Rosas FE, Timmermann C, Roseman L, Erritzoe D, Nutt DJ, Stamatakis EA, Spreng RN, Xing L, Huttner WB, Carhart-Harris RL.

    01/11/2024
    Genetic variation of the 5-HT1A rs6295, 5-HT2A rs6311, and CNR1 rs1049353 and an altered endocannabinoid system in depressed patients.

    Genetic variation of the 5-HT1A rs6295, 5-HT2A rs6311, and CNR1 rs1049353 and an altered endocannabinoid system in depressed patients.
    Obermanns J, Meiser H, Hoberg S, Vesterager CS, Schulz F, Juckel G, Emons B., Free PMC Article

    12/27/2023
    In Vivo Serotonin 5-HT2A Receptor Availability and Its Relationship with Aggression Traits in Healthy Individuals: A Positron Emission Tomography Study with C-11 MDL100907.

    In Vivo Serotonin 5-HT2A Receptor Availability and Its Relationship with Aggression Traits in Healthy Individuals: A Positron Emission Tomography Study with C-11 MDL100907.
    Kim JH, Kim HK, Son YD, Kim JH., Free PMC Article

    11/16/2023
    Association between the rs6313 polymorphism in the 5-HTR2A gene and the efficacy of antipsychotic drugs.

    Association between the rs6313 polymorphism in the 5-HTR2A gene and the efficacy of antipsychotic drugs.
    Wang Y, Tan X, Chen Z, Zhang B, Gao Y, Wang Y., Free PMC Article

    10/30/2023
    Association between single-nucleotide polymorphisms in serotonin receptor 2A and melatonin receptor 1A genes and pain after root canal treatment.

    Association between single-nucleotide polymorphisms in serotonin receptor 2A and melatonin receptor 1A genes and pain after root canal treatment.
    Meyfarth SRS, Tavares JDS, Guimarães LDS, Silva EAB, Gaio DC, Ecker MB, Brancher JA, Küchler EC, Silva-Sousa AC, de Sousa-Neto MD, Antunes LAA, Antunes LS.

    08/19/2023
    Prognostic and immunomodulatory roles of schizophrenia-associated genes HTR2A, COMT, and PRODH in pan-cancer analysis and glioma survival prediction model.

    Prognostic and immunomodulatory roles of schizophrenia-associated genes HTR2A, COMT, and PRODH in pan-cancer analysis and glioma survival prediction model.
    Shen J, Wang Q, Lu F, Xu H, Wang P, Feng Y., Free PMC Article

    08/16/2023
    His452Tyr 5-HT2A polymorphism and intravaginal ejaculation latency time in Dutch men with lifelong premature ejaculation.

    His452Tyr 5-HT(2A) polymorphism and intravaginal ejaculation latency time in Dutch men with lifelong premature ejaculation.
    van Raaij JJ, Hua KH, de Vries F, Janssen PKC.

    08/7/2023
    Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and HTR2A, HTR2C, and MAOB Gene Polymorphisms in Asthma.

    Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and HTR2A, HTR2C, and MAOB Gene Polymorphisms in Asthma.
    Konjevod M, Sreter KB, Popovic-Grle S, Lampalo M, Tudor L, Jukic I, Nedic Erjavec G, Bingulac-Popovic J, Safic Stanic H, Nikolac Perkovic M, Markeljevic J, Samarzija M, Pivac N, Svob Strac D., Free PMC Article

    06/2/2023
    Association of GABRG3, GABRB3, HTR2A gene variants with autism spectrum disorder.

    Association of GABRG3, GABRB3, HTR2A gene variants with autism spectrum disorder.
    Coskunpinar EM, Tur S, Cevher Binici N, Yazan Songür C.

    05/30/2023
    The crosstalk between 5-HT2AR and mGluR2 in schizophrenia.

    The crosstalk between 5-HT(2A)R and mGluR2 in schizophrenia.
    Saha S, González-Maeso J., Free PMC Article

    03/28/2023
    The contribution of the 5-hydroxytryptamine receptor 2 A gene polymorphisms rs6311 and rs6313 to Schizophrenia in Iran.

    The contribution of the 5-hydroxytryptamine receptor 2 A gene polymorphisms rs6311 and rs6313 to Schizophrenia in Iran.
    Massoud S, Salmanian M, Tabibian M, Ghamari R, Tavabe Ghavami TS, Alizadeh F.

    03/16/2023
    Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development.

    Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development.
    Nikolić J, Vukojević K, Šoljić V, Mišković J, Orlović Vlaho M, Saraga-Babić M, Filipović N., Free PMC Article

    02/17/2023
    Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis.

    Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis.
    Zhao J, Xu L, Chang C, Jiang P, Wei K, Shi Y, Xu L, Zheng Y, Shan Y, Bian Y, Li L, Guo S, Schrodi SJ, Wang R, He D., Free PMC Article

    01/14/2023
    Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse.

    Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse.
    Alrfooh A, Smith RM., Free PMC Article

    10/15/2022
    [Association of gene polymorphisms DRD3 rs6280, COMT rs4680 and HTR2A rs7322347 with schizophrenia].", trans "Assotsiatsiya geneticheskikh polimorfizmov rs6280 gena DRD3, rs4680 gena COMT, rs7322347 gena HTR2A s shizofreniei.

    [Association of gene polymorphisms DRD3 rs6280, COMT rs4680 and HTR2A rs7322347 with schizophrenia].
    Sofronov AG, Dobrovolskaya AE, Morozova AY, Gorina EA, Kolchev SA, Gvozdetckii AN.

    08/6/2022
    Indicators of Immune and Neurohumoral Profile in Women of Fertile Age with Functional Disorders of the Autonomic Nervous System Associated with Polymorphic Variants of the HTR2A (rs7997012) and TP53 (rs1042522) Genes.

    Indicators of Immune and Neurohumoral Profile in Women of Fertile Age with Functional Disorders of the Autonomic Nervous System Associated with Polymorphic Variants of the HTR2A (rs7997012) and TP53 (rs1042522) Genes.
    Dolgikh OV, Zaitseva NV, Nikonoshina NA, Alekseev VB.

    07/9/2022
    Association of 5-HTR2A T102C and A-1438G polymorphisms with clinical response to atypical antipsychotic treatment in schizophrenia: A meta-analysis.

    Association of 5-HTR2A T102C and A-1438G polymorphisms with clinical response to atypical antipsychotic treatment in schizophrenia: A meta-analysis.
    Yan P, Gao B, Wang S, Wang S, Li J, Song M.

    03/19/2022
    Associations between the 1438A/G, 102T/C, and rs7997012G/A polymorphisms of HTR2A and the safety and efficacy of antidepressants in depression: a meta-analysis.

    Associations between the 1438A/G, 102T/C, and rs7997012G/A polymorphisms of HTR2A and the safety and efficacy of antidepressants in depression: a meta-analysis.
    Wan YS, Zhai XJ, Tan HA, Ai YS, Zhao LB.

    01/15/2022
    Serotonin 5-HT2A receptor activity mediates adipocyte differentiation through control of adipogenic gene expression.

    Serotonin 5-HT(2A) receptor activity mediates adipocyte differentiation through control of adipogenic gene expression.
    Yu B, Battaglia DM, Foster TP, Nichols CD., Free PMC Article

    01/1/2022
    Is there an association of genetic polymorphisms of the catechol-O-methyltransferase gene (rs165656 and rs174675) and the 5-hydroxytryptamine receptor 2A gene (rs4941573 and rs6313) with sleep bruxism in individuals with obstructive sleep apnea?

    Is there an association of genetic polymorphisms of the catechol-O-methyltransferase gene (rs165656 and rs174675) and the 5-hydroxytryptamine receptor 2A gene (rs4941573 and rs6313) with sleep bruxism in individuals with obstructive sleep apnea?
    Duarte J, Pauletto P, Polmann H, Réus JC, de Souza JF, Gaio DC, Brancher JA, Vieira A, Machado-Souza C, de Souza Melo G, Maia IS, De Luca Canto G.

    12/18/2021
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