| 5-HT receptor agonist Valerenic Acid enhances the innate immunity signal and suppresses glioblastoma cell growth and invasion. | 5-HT receptor agonist Valerenic Acid enhances the innate immunity signal and suppresses glioblastoma cell growth and invasion.
Lu Q, Ding Y, Li Y, Lu Q., Free PMC Article | 11/22/2021 |
| results provide further supportive evidence of the effect of HTR1A and HTR5A on the etiology of schizophrenia and suggest that the selected genetic variations in HTR5A may be involved in impaired executive function. | Evaluation of association of common variants in HTR1A and HTR5A with schizophrenia and executive function.
Guan F, Lin H, Chen G, Li L, Chen T, Liu X, Han J, Li T., Free PMC Article | 06/2/2018 |
| Results suggest that TPH1 218A/C and HTR5A 12A/T polymorphisms cannot predict treatment response in major depression | Serotonin-related polymorphisms in TPH1 and HTR5A genes are not associated with escitalopram treatment response in Korean patients with major depression.
Kim YG, Chang HS, Won ES, Ham BJ, Lee MS. | 02/28/2015 |
| Childhood anxiousness did not mediate the effects of HTR2A and HTR5A on mood disorders. | Differences and similarities in the serotonergic diathesis for suicide attempts and mood disorders: a 22-year longitudinal gene-environment study.
Brezo J, Bureau A, Mérette C, Jomphe V, Barker ED, Vitaro F, Hébert M, Carbonneau R, Tremblay RE, Turecki G, Brezo J, Bureau A, Mérette C, Jomphe V, Barker ED, Vitaro F, Hébert M, Carbonneau R, Tremblay RE, Turecki G. | 12/4/2010 |
| Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels | Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels.
Zhang Y, Smith EM, Baye TM, Eckert JV, Abraham LJ, Moses EK, Kissebah AH, Martin LJ, Olivier M, Zhang Y, Smith EM, Baye TM, Eckert JV, Abraham LJ, Moses EK, Kissebah AH, Martin LJ, Olivier M., Free PMC Articles: PMC3032280, PMC3032280 | 10/30/2010 |
| Association of a SNP of HTR5A gene is a susceptibility factor to bipolar disease in Bulgarian population. | Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Yosifova A, Mushiroda T, Stoianov D, Vazharova R, Dimova I, Karachanak S, Zaharieva I, Milanova V, Madjirova N, Gerdjikov I, Tolev T, Velkova S, Kirov G, Owen MJ, O'Donovan MC, Toncheva D, Nakamura Y, Yosifova A, Mushiroda T, Stoianov D, Vazharova R, Dimova I, Karachanak S, Zaharieva I, Milanova V, Madjirova N, Gerdjikov I, Tolev T, Velkova S, Kirov G, Owen MJ, O'Donovan MC, Toncheva D, Nakamura Y. | 02/22/2010 |
| Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator) | Differences and similarities in the serotonergic diathesis for suicide attempts and mood disorders: a 22-year longitudinal gene-environment study.
Brezo J, Bureau A, Mérette C, Jomphe V, Barker ED, Vitaro F, Hébert M, Carbonneau R, Tremblay RE, Turecki G, Brezo J, Bureau A, Mérette C, Jomphe V, Barker ED, Vitaro F, Hébert M, Carbonneau R, Tremblay RE, Turecki G. | 04/29/2009 |
| In individuals in Brazil with the A/A variant of the -1438G/A polymorphism of the 2A receptor gene, the effect of cultural consonance in family life on depressive symptoms over a 2 year period was larger than those with the G/A or G/G variants. | Cultural consonance, a 5HT2A receptor polymorphism, and depressive symptoms: a longitudinal study of gene x culture interaction in urban Brazil.
Dressler WW, Balieiro MC, Ribeiro RP, Dos Santos JE. | 01/21/2010 |
| Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.
Need AC, Keefe RS, Ge D, Grossman I, Dickson S, McEvoy JP, Goldstein DB., Free PMC Article | 02/11/2009 |
| N-glycosylation of the N6 residue is important for the membrane expression of this 5-HT5A neurotransmitter receptor; a requirement for receptor function. | Identification and functional significance of N-glycosylation of the 5-ht5A receptor.
Dutton AC, Massoura AN, Dover TJ, Andrews NA, Barnes NM. | 01/21/2010 |
| Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Polymorphisms in the SLC6A4 and HTR2A genes influence treatment outcome following antidepressant therapy.
Wilkie MJ, Smith G, Day RK, Matthews K, Smith D, Blackwood D, Reid IC, Wolf CR. | 04/3/2008 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the determination of platelet serotonin levels.
Coutinho AM, Sousa I, Martins M, Correia C, Morgadinho T, Bento C, Marques C, Ataíde A, Miguel TS, Moore JH, Oliveira G, Vicente AM. | 03/13/2008 |
| Meta-analysis of gene-disease association. (HuGE Navigator) | [Alcohol dependence and polymorphisms of serotonin-related genes].
Gorwood P, Lanfumey L, Hamon M. | 03/13/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (10) articlesA large-scale candidate gene association study of age at menarche and age at natural menopause.
He C, Kraft P, Chasman DI, Buring JE, Chen C, Hankinson SE, Paré G, Chanock S, Ridker PM, Hunter DJ. Association study of 182 candidate genes in anorexia nervosa.
Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB. Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels.
Zhang Y, Smith EM, Baye TM, Eckert JV, Abraham LJ, Moses EK, Kissebah AH, Martin LJ, Olivier M, Zhang Y, Smith EM, Baye TM, Eckert JV, Abraham LJ, Moses EK, Kissebah AH, Martin LJ, Olivier M. Association study of the serotoninergic system in migraine in the Spanish population.
Corominas R, Sobrido MJ, Ribasés M, Cuenca-León E, Blanco-Arias P, Narberhaus B, Roig M, Leira R, López-González J, Macaya A, Cormand B. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Yosifova A, Mushiroda T, Stoianov D, Vazharova R, Dimova I, Karachanak S, Zaharieva I, Milanova V, Madjirova N, Gerdjikov I, Tolev T, Velkova S, Kirov G, Owen MJ, O'Donovan MC, Toncheva D, Nakamura Y, Yosifova A, Mushiroda T, Stoianov D, Vazharova R, Dimova I, Karachanak S, Zaharieva I, Milanova V, Madjirova N, Gerdjikov I, Tolev T, Velkova S, Kirov G, Owen MJ, O'Donovan MC, Toncheva D, Nakamura Y. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. Genetic evaluation of the serotonergic system in chronic fatigue syndrome.
Smith AK, Dimulescu I, Falkenberg VR, Narasimhan S, Heim C, Vernon SD, Rajeevan MS. No association of attention-deficit/hyperactivity disorder with genes of the serotonergic pathway in Han Chinese subjects.
Li J, Wang Y, Zhou R, Wang B, Zhang H, Yang L, Faraone SV. Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers.
Turecki G, Sequeira A, Gingras Y, Séguin M, Lesage A, Tousignant M, Chawky N, Vanier C, Lipp O, Benkelfat C, Rouleau GA. Association of a 5-HT(5A) receptor polymorphism, Pro15Ser, to schizophrenia.
Iwata N, Ozaki N, Inada T, Goldman D. | 03/13/2008 |
| The receptor has been transiently expressed in Cos M6 cells and exhibits a pharmacological profile closely resembling the mouse and rat 5-HT5A receptors with high, specific binding for ergotamine and methiothepin. | Cloning and characterisation of the human 5-HT5A serotonin receptor.
Rees S, den Daas I, Foord S, Goodson S, Bull D, Kilpatrick G, Lee M. | 11/10/2005 |