| WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8. | WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.
Zhou L, Zhong Y, Wang F, Guo Y, Mao R, Xie H, Zhang Y, Li J., Free PMC Article | 03/15/2024 |
| Circulating IRF8-expressing CD123[+]CD127[+] lymphoid progenitors: key players in human hematopoiesis. | Circulating IRF8-expressing CD123(+)CD127(+) lymphoid progenitors: key players in human hematopoiesis.
Liang KL, Laurenti E, Taghon T., Free PMC Article | 08/30/2023 |
| Loss of IRF8 inhibits the growth of acute myeloid leukemia cells. | Loss of IRF8 inhibits the growth of acute myeloid leukemia cells.
Zhuang H, Li F, Xu Y, Pei R, Chen D, Liu X, Li S, Ye P, Yuan J, Lian J, Lu Y. | 08/10/2023 |
| Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis Patients. | Expression of Interferon Regulatory Factor 8 (IRF8) and Its Association with Infections in Dialysis Patients.
Friebus-Kardash J, Kuang F, Peitz T, Hamdan TA, Eisenberger U, Boss K, Kribben A, Lang KS, Jahn M., Free PMC Article | 08/2/2023 |
| Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. | Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Liang KL, Roels J, Lavaert M, Putteman T, Boehme L, Tilleman L, Velghe I, Pegoretti V, Van de Walle I, Sontag S, Vandewalle J, Vandekerckhove B, Leclercq G, Van Vlierberghe P, Libert C, Van Nieuwerburgh F, Fischer R, Kontermann RE, Pfizenmaier K, Doody G, Zenke M, Taghon T. | 03/9/2023 |
| IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes. | IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes.
Poschel DB, Kehinde-Ige M, Klement JD, Yang D, Merting AD, Savage NM, Shi H, Liu K., Free PMC Article | 02/11/2023 |
| Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer. | Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer.
Nixon BG, Kuo F, Ji L, Liu M, Capistrano K, Do M, Franklin RA, Wu X, Kansler ER, Srivastava RM, Purohit TA, Sanchez A, Vuong L, Krishna C, Wang X, Morse Iii HC, Hsieh JJ, Chan TA, Murphy KM, Moon JJ, Hakimi AA, Li MO., Free PMC Article | 11/19/2022 |
| IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas. | IRF8 as a Novel Marker to Differentiate Between CD30-Positive Large Cell Lymphomas.
McQuaid DC, Katz SG, Xu ML., Free PMC Article | 08/13/2022 |
| IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia. | IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia.
Huang X, Ma T, Zhu Y, Jiao B, Yu S, Wang K, Mi JQ, Ren R. | 07/30/2022 |
| Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery. | Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.
Zhou T, Zhu X, Ye Z, Wang YF, Yao C, Xu N, Zhou M, Ma J, Qin Y, Shen Y, Tang Y, Yin Z, Xu H, Zhang Y, Zang X, Ding H, Yang W, Guo Y, Harley JB, Namjou B, Kaufman KM, Kottyan LC, Weirauch MT, Hou G, Shen N., Free PMC Article | 04/16/2022 |
| IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma. | IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma.
Elfrink S, Ter Beest M, Janssen L, Baltissen MP, Jansen PWTC, Kenyon AN, Steen RM, de Windt D, Hagemann PM, Hess C, van Spronsen DJ, Hoevenaars B, van der Spek E, Xu-Monette ZY, Young KH, Kaffa C, Bervoets S, van Heek J, Hesius E, de Winde CM, Vermeulen M, van den Brand M, Scheijen B, van Spriel AB., Free PMC Article | 04/16/2022 |
| Global assessment of IRF8 as a novel cancer biomarker. | Global assessment of IRF8 as a novel cancer biomarker.
McQuaid DC, Panse G, Wang WL, Pinkus GS, Katz SG, Xu ML., Free PMC Article | 04/9/2022 |
| Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP. | Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP.
Wang H, Joshi P, Hong SH, Maye PF, Rowe DW, Shin DG., Free PMC Article | 01/15/2022 |
| High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer. | High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer.
Gatti G, Betts C, Rocha D, Nicola M, Grupe V, Ditada C, Nuñez NG, Roselli E, Araya P, Dutto J, Boffelli L, Fernández E, Coussens LM, Maccioni M., Free PMC Article | 01/8/2022 |
| Downregulated IRF8 in Monocytes and Macrophages of Patients with Systemic Sclerosis May Aggravate the Fibrotic Phenotype. | Downregulated IRF8 in Monocytes and Macrophages of Patients with Systemic Sclerosis May Aggravate the Fibrotic Phenotype.
Ototake Y, Yamaguchi Y, Asami M, Komitsu N, Akita A, Watanabe T, Kanaoka M, Kurotaki D, Tamura T, Aihara M. | 11/27/2021 |
| Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype. | Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.
de Groen RAL, van Eijk R, Böhringer S, van Wezel T, Raghoo R, Ruano D, Jansen PM, Briaire-de Bruijn I, de Groot FA, Kleiverda K, Te Boome L, Terpstra V, Levenga H, Nicolae A, Posthuma EFM, Focke-Snieders I, Hardi L, den Hartog WCE, Bohmer LH, Hogendoorn PCW, van den Berg A, Diepstra A, Nijland M, Lugtenburg PJ, Kersten MJ, Pals ST, Veelken H, Bovée JVMG, Cleven AHG, Vermaat JSP., Free PMC Article | 11/6/2021 |
| ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency. | ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.
Cao Z, Budinich KA, Huang H, Ren D, Lu B, Zhang Z, Chen Q, Zhou Y, Huang YH, Alikarami F, Kingsley MC, Lenard AK, Wakabayashi A, Khandros E, Bailis W, Qi J, Carroll MP, Blobel GA, Faryabi RB, Bernt KM, Berger SL, Shi J., Free PMC Article | 10/23/2021 |
| IRF8 is a Reliable Monoblast Marker for Acute Monocytic Leukemias. | IRF8 is a Reliable Monoblast Marker for Acute Monocytic Leukemias.
Katz SG, Edappallath S, Xu ML. | 10/9/2021 |
| PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome via Regulating Its Expression in Human Macrophages. | PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome via Regulating Its Expression in Human Macrophages.
Yashiro T, Yamamoto M, Araumi S, Hara M, Yogo K, Uchida K, Kasakura K, Nishiyama C., Free PMC Article | 10/2/2021 |
| Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis. | Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis.
Gardner AI, Wu Y, Verhaegh R, Liu Y, Wilker B, Soddemann M, Keitsch S, Edwards MJ, Haq IJ, Kamler M, Becker KA, Brodlie M, Gulbins E., Free PMC Article | 08/28/2021 |
| Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. | Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans.
Cytlak U, Resteu A, Pagan S, Green K, Milne P, Maisuria S, McDonald D, Hulme G, Filby A, Carpenter B, Queen R, Hambleton S, Hague R, Lango Allen H, Thaventhiran JED, Doody G, Collin M, Bigley V., Free PMC Article | 04/17/2021 |
| SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes. | SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes.
Zhang Y, Yang K, Yang J, Lao Y, Deng L, Deng G, Yi J, Sun X, Wang Q. | 03/13/2021 |
| Single-cell RNA sequencing of immune cells in gastric cancer patients. | Single-cell RNA sequencing of immune cells in gastric cancer patients.
Fu K, Hui B, Wang Q, Lu C, Shi W, Zhang Z, Rong D, Zhang B, Tian Z, Tang W, Cao H, Wang X, Chen Z., Free PMC Article | 01/23/2021 |
| Loss of a Negative Feedback Loop between IRF8 and AR Promotes Prostate Cancer Growth and Enzalutamide Resistance. | Loss of a Negative Feedback Loop between IRF8 and AR Promotes Prostate Cancer Growth and Enzalutamide Resistance.
Wu H, You L, Li Y, Zhao Z, Shi G, Chen Z, Wang Z, Li X, Du S, Ye W, Gao X, Duan J, Cheng Y, Tao W, Bian J, Zhou JR, Zhu Q, Yang Y., Free PMC Article | 11/21/2020 |
| Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies. | Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies.
Matana A, Boutin T, Torlak V, Brdar D, Gunjača I, Kolčić I, Boraska Perica V, Punda A, Polašek O, Barbalić M, Hayward C, Zemunik T. | 11/21/2020 |