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    APOC1 apolipoprotein C1 [ Homo sapiens (human) ]

    Gene ID: 341, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer.

    APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer.
    Yang S, Du J, Wang W, Zhou D, Xi X., Free PMC Article

    03/27/2024
    Protective Association of APOC1/rs4420638 with Risk of Obesity: A case-control Study in Portuguese Children.

    Protective Association of APOC1/rs4420638 with Risk of Obesity: A case-control Study in Portuguese Children.
    Manco L, Albuquerque D, Rodrigues D, Machado-Rodrigues AM, Padez C., Free PMC Article

    03/4/2024
    miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFbeta2 signaling pathway.

    miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway.
    Yang Z, Yang L, Sun Z, Rong Y, Bai C, Dong Q, Jian L., Free PMC Article

    11/22/2023
    APOC1 as a novel diagnostic biomarker for DN based on machine learning algorithms and experiment.

    APOC1 as a novel diagnostic biomarker for DN based on machine learning algorithms and experiment.
    Yu K, Li S, Wang C, Zhang Y, Li L, Fan X, Fang L, Li H, Yang H, Sun J, Yang X., Free PMC Article

    03/27/2023
    ApoC1 promotes glioma metastasis by enhancing epithelial-mesenchymal transition and activating the STAT3 pathway.

    ApoC1 promotes glioma metastasis by enhancing epithelial-mesenchymal transition and activating the STAT3 pathway.
    Liang R, Zhang G, Xu W, Liu W, Tang Y.

    02/14/2023
    Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis.

    Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis.
    Zheng XJ, Chen WL, Yi J, Li W, Liu JY, Fu WQ, Ren LW, Li S, Ge BB, Yang YH, Zhang YZ, Yang H, Du GH, Wang Y, Wang JH., Free PMC Article

    01/28/2023
    ZNF460 mediates epithelial-mesenchymal transition to promote gastric cancer progression by transactivating APOC1 expression.

    ZNF460 mediates epithelial-mesenchymal transition to promote gastric cancer progression by transactivating APOC1 expression.
    An L, Liu Y.

    01/14/2023
    Associations of the APOE epsilon2 and epsilon4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers.

    Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers.
    Kulminski AM, Jain-Washburn E, Loiko E, Loika Y, Feng F, Culminskaya I, Alzheimer’s Disease Neuroimaging Initiative., Free PMC Article

    01/14/2023
    Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencing.

    Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencing.
    Hao X, Zheng Z, Liu H, Zhang Y, Kang J, Kong X, Rong D, Sun G, Sun G, Liu L, Yu H, Tang W, Wang X., Free PMC Article

    10/8/2022
    Systematic pan-cancer analysis identifies APOC1 as an immunological biomarker which regulates macrophage polarization and promotes tumor metastasis.

    Systematic pan-cancer analysis identifies APOC1 as an immunological biomarker which regulates macrophage polarization and promotes tumor metastasis.
    Ren L, Yi J, Yang Y, Li W, Zheng X, Liu J, Li S, Yang H, Zhang Y, Ge B, Zhang S, Fu W, Dong D, Du G, Wang X, Wang J.

    09/24/2022
    Apolipoprotein C1 (APOC1), A Candidate Diagnostic Serum Biomarker for Breast Cancer Identified by Serum Proteomics Study.

    Apolipoprotein C1 (APOC1), A Candidate Diagnostic Serum Biomarker for Breast Cancer Identified by Serum Proteomics Study.
    Yan Y, Zhou Y, Wang K, Qiao Y, Zhao L, Chen M.

    06/18/2022
    Associations of genetic variants of lysophosphatidylcholine metabolic enzymes with levels of serum lipids.

    Associations of genetic variants of lysophosphatidylcholine metabolic enzymes with levels of serum lipids.
    Wang H, Wang Y, Song JY, Zhang PP, Song QY, Li CX, Li L, Wang HJ.

    06/18/2022
    Effect of gene polymorphism on bleeding complications in Chinese Han patients taking warfarin.

    Effect of gene polymorphism on bleeding complications in Chinese Han patients taking warfarin.
    Xia X, Fu J, Wu T, Chen W, Jiang S, Lv M, Zhang J.

    02/26/2022
    Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk.

    Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk.
    Kulminski AM, Philipp I, Shu L, Culminskaya I., Free PMC Article

    02/19/2022
    Expression of apolipoprotein C1 in clear cell renal cell carcinoma: An oncogenic gene and a prognostic marker.

    Expression of apolipoprotein C1 in clear cell renal cell carcinoma: An oncogenic gene and a prognostic marker.
    Wang HJ, Ma YX, Wang AH, Jiang YS, Jiang XZ.

    01/8/2022
    Overexpression of Apolipoprotein C1 (APOC1) in Clear Cell Renal Cell Carcinoma and Its Prognostic Significance.

    Overexpression of Apolipoprotein C1 (APOC1) in Clear Cell Renal Cell Carcinoma and Its Prognostic Significance.
    Xiao H, Xu Y., Free PMC Article

    05/29/2021
    ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3.

    ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3.
    Li YL, Wu LW, Zeng LH, Zhang ZY, Wang W, Zhang C, Lin NM.

    01/16/2021
    Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.

    Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
    Luningham JM, Chen J, Tang S, De Jager PL, Bennett DA, Buchman AS, Yang J., Free PMC Article

    12/5/2020
    [Analysis of rs4420638A/G and -317H1/H2 polymorphisms of APOC1 gene among Chinese patients with pre-eclampsia].

    [Analysis of rs4420638A/G and -317H1/H2 polymorphisms of APOC1 gene among Chinese patients with pre-eclampsia].
    Sun Y, Fan P, Liu Q, Bai H, Liu X, Zhou M, Wu Y, Guan L, Li S.

    11/21/2020
    Diagnostic and prognostic significance of mRNA expressions of apolipoprotein A and C family genes in hepatitis B virus-related hepatocellular carcinoma.

    Diagnostic and prognostic significance of mRNA expressions of apolipoprotein A and C family genes in hepatitis B virus-related hepatocellular carcinoma.
    Wang X, Gong Y, Deng T, Zhang L, Liao X, Han C, Yang C, Huang J, Wang Q, Song X, Zhang T, Yu T, Zhu G, Ye X, Peng T.

    09/19/2020
    Against LuzP6 and commercial antibodies against ApoC1, C12orf75 and OCC-1 and analyzed.

    Assessment of ApoC1, LuzP6, C12orf75 and OCC-1 in cystic glioblastoma using MALDI-TOF mass spectrometry, immunohistochemistry and qRT-PCR.
    Evangelou P, Groll M, Oppermann H, Gaunitz F, Eisenlöffel C, Müller W, Eschrich K, Schänzer A, Nestler U., Free PMC Article

    05/2/2020
    ApoC1 regulates in a complex fashion, the activity of enzymes and receptors involved in the metabolism of VLDL and HDL. apoC1 employs a recurrent structural motif-the amphipathic helix-to modulate a variety of biological processes that connect at a molecular level directly or indirectly to the transport and/remodeling of lipids, mostly cholesterol, as a precursor of steroid hormones involved in various processes. [review]

    Apolipoprotein C1: Its Pleiotropic Effects in Lipid Metabolism and Beyond.
    Fuior EV, Gafencu AV., Free PMC Article

    04/25/2020
    structure of human apolipoprotein C-1 in four different crystal forms

    The structure of human apolipoprotein C-1 in four different crystal forms.
    McPherson A, Larson SB., Free PMC Article

    02/15/2020
    Association between APOC1 rs11568822 polymorphism and Alzheimer's disease risk can be explained by linkage disequilibrium with the APOE locus.

    Association between selected cholesterol-related gene polymorphisms and Alzheimer's disease in a Turkish cohort.
    Guven G, Vurgun E, Bilgic B, Hanagasi H, Gurvit H, Ozer E, Lohmann E, Erginel-Unaltuna N.

    09/14/2019
    PPARgamma knockdown resulted in increased levels of TOMM40, APOE and APOC1 -mRNAs, showing the strongest impact on APOE transcript levels.

    The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster.
    Subramanian S, Gottschalk WK, Kim SY, Roses AD, Chiba-Falek O., Free PMC Article

    12/1/2018
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