U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    IDH2 isocitrate dehydrogenase (NADP(+)) 2 [ Homo sapiens (human) ]

    Gene ID: 3418, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    IDH2 regulates U2AF1 expression and hydroxymethylation in MDS patients.

    IDH2 regulates U2AF1 expression and hydroxymethylation in MDS patients.
    Cheng H, Liu Y, Cheng M, Li W, Sun M, Tang Q, Ma J, Li P, Gong T.

    10/2/2024
    Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma.

    Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma.
    Xu S, Cao L, Chen R, Ye C, Li Q, Jiang Q, Yan F, Wan M, Zhang X, Ruan J., Free PMC Article

    09/11/2024
    Epigenetic dysregulation in cancers by isocitrate dehydrogenase 2 (IDH2).

    Epigenetic dysregulation in cancers by isocitrate dehydrogenase 2 (IDH2).
    Nayarisseri A, Bandaru S, Khan A, Sharma K, Bhrdwaj A, Kaur M, Ghosh D, Chopra I, Panicker A, Kumar A, Saravanan P, Belapurkar P, Mendonça Junior FJB, Singh SK.

    07/26/2024
    Methylation-Based Characterization of a New IDH2 Mutation in Sinonasal Undifferentiated Carcinoma.

    Methylation-Based Characterization of a New IDH2 Mutation in Sinonasal Undifferentiated Carcinoma.
    Burgermeister S, Stoykova S, Krebs FS, Zoete V, Mbefo M, Egervari K, Reinhard A, Bisig B, Hewer E., Free PMC Article

    07/17/2024
    IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation.

    IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation.
    Yang J, Chen J, Chang J, Sun X, Wei Q, Cai X, Cao P., Free PMC Article

    06/24/2024
    Isocitrate dehydrogenase 2 regulates the proliferation of triple-negative breast cancer through the ferroptosis pathway.

    Isocitrate dehydrogenase 2 regulates the proliferation of triple-negative breast cancer through the ferroptosis pathway.
    Zhang C, Zhou Y, Chen T, Bhushan S, Sun S, Zhang P, Yang Y., Free PMC Article

    06/21/2024
    Clinical and imaging characteristics of supratentorial glioma with IDH2 mutation.

    Clinical and imaging characteristics of supratentorial glioma with IDH2 mutation.
    Ikeda S, Sakata A, Arakawa Y, Mineharu Y, Makino Y, Takeuchi Y, Fushimi Y, Okuchi S, Nakajima S, Otani S, Nakamoto Y.

    06/5/2024
    Genetic Polymorphism Study of IDH 1/2 and TET2 Genes in Acute Myeloid leukemia Patients.

    Genetic Polymorphism Study of IDH 1/2 and TET2 Genes in Acute Myeloid leukemia Patients.
    Atef M, Shafik NF, H A Hassan N, Allam RM, El-Meligui YM, Abdelaziz H., Free PMC Article

    01/8/2024
    IDH2 mutations in acute myeloid leukemia.

    IDH2 mutations in acute myeloid leukemia.
    Babakhanlou R, DiNardo C, Borthakur G.

    11/13/2023
    The impact of IDH and NAT2 gene polymorphisms in acute myeloid leukemia risk and overall survival in an Arab population: A case-control study.

    The impact of IDH and NAT2 gene polymorphisms in acute myeloid leukemia risk and overall survival in an Arab population: A case-control study.
    Al-Khatib SM, Ababneh O, Abushukair H, Abdo N, Al-Eitan LN., Free PMC Article

    10/26/2023
    Recurrent IDH2 Mutations in Salivary Gland Striated Duct Adenoma Define an Expanded Histologic Spectrum Distinct From Canalicular Adenoma.

    Recurrent IDH2 Mutations in Salivary Gland Striated Duct Adenoma Define an Expanded Histologic Spectrum Distinct From Canalicular Adenoma.
    Rooper LM, Agaimy A, Assaad A, Bal M, Eugene H, Gagan J, Nonogaki H, Palsgrove DN, Shah A, Stelow E, Stoehr R, Thompson LDR, Weinreb I, Bishop JA.

    02/28/2023
    IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-kappaB signaling to promote colorectal cancer progression.

    IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
    He X, Wu N, Li R, Zhang H, Zhao Y, Nie Y, Wu J.

    02/27/2023
    IDH2 stabilizes HIF-1alpha-induced metabolic reprogramming and promotes chemoresistance in urothelial cancer.

    IDH2 stabilizes HIF-1α-induced metabolic reprogramming and promotes chemoresistance in urothelial cancer.
    Shigeta K, Hasegawa M, Hishiki T, Naito Y, Baba Y, Mikami S, Matsumoto K, Mizuno R, Miyajima A, Kikuchi E, Saya H, Kosaka T, Oya M., Free PMC Article

    02/27/2023
    Impact of IDH1 and IDH2 mutation detection at diagnosis and in remission in patients with AML receiving allogeneic transplantation.

    Impact of IDH1 and IDH2 mutation detection at diagnosis and in remission in patients with AML receiving allogeneic transplantation.
    Bill M, Jentzsch M, Bischof L, Kohlschmidt J, Grimm J, Schmalbrock LK, Backhaus D, Brauer D, Goldmann K, Franke GN, Vucinic V, Niederwieser D, Mims AS, Platzbecker U, Eisfeld AK, Schwind S., Free PMC Article

    02/11/2023
    IDH2[R172] mutation in angioimmunoblastic T-cell lymphoma: A retrospective multicenter case series.

    IDH2(R172) mutation in angioimmunoblastic T-cell lymphoma: A retrospective multicenter case series.
    Riva M, Tisi MC, Bertorelle R, Famengo B, D'Amore ESG, Pizzi M, Parisi A, Boscato E, Mazzucco M, Semenzato G, Krampera M, Gherlinzoni F, Trentin L, Ruggeri M, Visco C, Stefani PM, Piazza F.

    01/28/2023
    Effects of cancer-associated point mutations on the structure, function, and stability of isocitrate dehydrogenase 2.

    Effects of cancer-associated point mutations on the structure, function, and stability of isocitrate dehydrogenase 2.
    Chen X, Yang P, Qiao Y, Ye F, Wang Z, Xu M, Han X, Song L, Wu Y, Ou WB., Free PMC Article

    11/12/2022
    Nrf2 transcriptional upregulation of IDH2 to tune mitochondrial dynamics and rescue angiogenic function of diabetic EPCs.

    Nrf2 transcriptional upregulation of IDH2 to tune mitochondrial dynamics and rescue angiogenic function of diabetic EPCs.
    Dai X, Wang K, Fan J, Liu H, Fan X, Lin Q, Chen Y, Chen H, Li Y, Liu H, Chen O, Chen J, Li X, Ren D, Li J, Conklin DJ, Wintergerst KA, Li Y, Cai L, Deng Z, Yan X, Tan Y., Free PMC Article

    10/8/2022
    Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation.

    Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation.
    Kunadt D, Stasik S, Metzeler KH, Röllig C, Schliemann C, Greif PA, Spiekermann K, Rothenberg-Thurley M, Krug U, Braess J, Krämer A, Hochhaus A, Scholl S, Hilgendorf I, Brümmendorf TH, Jost E, Steffen B, Bug G, Einsele H, Görlich D, Sauerland C, Schäfer-Eckart K, Krause SW, Hänel M, Hanoun M, Kaufmann M, Wörmann B, Kramer M, Sockel K, Egger-Heidrich K, Herold T, Ehninger G, Burchert A, Platzbecker U, Berdel WE, Müller-Tidow C, Hiddemann W, Serve H, Stelljes M, Baldus CD, Neubauer A, Schetelig J, Thiede C, Bornhäuser M, Middeke JM, Stölzel F, A. M. L. Cooperative Group (AMLCG), Study Alliance Leukemia (SAL)., Free PMC Article

    09/24/2022
    IDH1/2 Mutations in Sinonasal Undifferentiated Carcinomas : Previously Undescribed IDH2 R172K and R140x Variants.

    IDH1/2 Mutations in Sinonasal Undifferentiated Carcinomas : Previously Undescribed IDH2 R172K and R140x Variants.
    Kakkar A, Rathor A, Ashraf SF, Singh V, Sikka K, Jain D.

    08/27/2022
    Differential prognostic impact of IDH1 and IDH2 mutations in chronic myelomonocytic leukemia.

    Differential prognostic impact of IDH1 and IDH2 mutations in chronic myelomonocytic leukemia.
    Walsh C, Hunter A, Lasho T, Finke C, Ketterling R, Komrokji R, Tefferi A, Mangaonkar A, Howard M, Gangat N, Al-Kali A, Ali NA, Padron E, Patnaik MM.

    08/27/2022
    Isocitrate Dehydrogenase IDH1 and IDH2 Mutations in Human Cancer: Prognostic Implications for Gliomas.

    Isocitrate Dehydrogenase IDH1 and IDH2 Mutations in Human Cancer: Prognostic Implications for Gliomas.
    Murugan AK, Alzahrani AS., Free PMC Article

    08/27/2022
    The correlation analysis of TERT promoter mutations with IDH1/2 mutations and 1p/19q detected in human gliomas.

    The correlation analysis of TERT promoter mutations with IDH1/2 mutations and 1p/19q detected in human gliomas.
    Xu J, Xu FP, Liu ZH, Cui Q, Zhang KP, Li Z., Free PMC Article

    08/6/2022
    Plk1 regulates mutant IDH1 enzyme activity and mutant IDH2 ubiquitination in mitosis.

    Plk1 regulates mutant IDH1 enzyme activity and mutant IDH2 ubiquitination in mitosis.
    Saikiran Reddy M, Bhattacharjee D, Jain N.

    07/16/2022
    Determination of IDH1, IDH2, MGMT, TERT and ATRX Gene Mutations in Glial Tumors.

    Determination of IDH1, IDH2, MGMT, TERT and ATRX Gene Mutations in Glial Tumors.
    Yaltirik CK, Yilmaz SG, Ozdogan S, Bilgin EY, Barut Z, Ture U, Isbir T., Free PMC Article

    07/2/2022
    Association between genetic variations of mitochondrial isocitrate dehydrogenase (IDH2) and acute myocardial infarction.

    Association between genetic variations of mitochondrial isocitrate dehydrogenase (IDH2) and acute myocardial infarction.
    Watany MM, Nagi Abd-Ellatif R, Ezzelregal Abdeldayem M, El-Sayed El-Horany H.

    05/21/2022
    firstprevious page of 17 nextlast