| IFI16 Positively Regulates RIG-I-Mediated Type I Interferon Production in a STING-Independent Manner. | IFI16 Positively Regulates RIG-I-Mediated Type I Interferon Production in a STING-Independent Manner.
Shi X, Wei M, Feng Y, Yang Y, Zhang X, Chen H, Xing Y, Wang K, Wang W, Wang L, Wang A, Zhang G. | 04/12/2024 |
| IFI16 Is Indispensable for Promoting HIF-1alpha-Mediated APOL1 Expression in Human Podocytes under Hypoxic Conditions. | IFI16 Is Indispensable for Promoting HIF-1α-Mediated APOL1 Expression in Human Podocytes under Hypoxic Conditions.
Randle RK, Amara VR, Popik W., Free PMC Article | 04/2/2024 |
| Association of salivary levels of DNA sensing inflammasomes AIM2, IFI16, and cytokine IL18 with periodontitis and diabetes. | Association of salivary levels of DNA sensing inflammasomes AIM2, IFI16, and cytokine IL18 with periodontitis and diabetes.
Arunachalam LT, Suresh S, Lavu V, Vedamanickam S, Viswanathan S, Thirumalai Nathan RD. | 03/7/2024 |
| IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1alpha. | IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1α.
Azumi Y, Koma YI, Tsukamoto S, Kitamura Y, Ishihara N, Yamanaka K, Nakanishi T, Miyako S, Urakami S, Tanigawa K, Kodama T, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H., Free PMC Article | 11/28/2023 |
| Effects of AIM2 and IFI16 on Infectious Diseases and Inflammation. | Effects of AIM2 and IFI16 on Infectious Diseases and Inflammation.
Fan Z, Chen R, Yin W, Xie X, Wang S, Hao C. | 09/20/2023 |
| IFI16 phase separation via multi-phosphorylation drives innate immune signaling. | IFI16 phase separation via multi-phosphorylation drives innate immune signaling.
Liu D, Lum KK, Treen N, Núñez CT, Yang J, Howard TR, Levine M, Cristea IM., Free PMC Article | 07/27/2023 |
| IFI16/Ifi202 released from breast cancer induces secretion of inflammatory cytokines from macrophages and promotes tumor growth. | IFI16/Ifi202 released from breast cancer induces secretion of inflammatory cytokines from macrophages and promotes tumor growth.
Lim GY, Cho SW, Ka NL, Lee KH, Im SA, Kim SS, Hwang S, Lee MO. | 07/25/2023 |
| Filament assembly underpins the double-stranded DNA specificity of AIM2-like receptors. | Filament assembly underpins the double-stranded DNA specificity of AIM2-like receptors.
Garg A, Stallings CM, Sohn J., Free PMC Article | 04/12/2023 |
| Inflammasome genes polymorphisms are associated with progression to mechanical ventilation and death in a cohort of hospitalized COVID-19 patients in a reference hospital in Rio de Janeiro, Brazil. | Inflammasome genes polymorphisms are associated with progression to mechanical ventilation and death in a cohort of hospitalized COVID-19 patients in a reference hospital in Rio de Janeiro, Brazil.
Neira-Goulart M, de Sá NBR, Ribeiro-Alves M, Perazzo H, Geraldo KM, Ribeiro MPD, Cardoso SW, Grinsztejn B, Veloso VG, Rodrigues Gomes L, Cazote ADS, de Almeida DV, Giacoia-Gripp CBW, Côrtes FH, Morgado MG., Free PMC Article | 03/23/2023 |
| Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells. | Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells.
Wang J, Qin X, Huang Y, Zhang G, Liu Y, Cui Y, Wang Y, Pei J, Ma S, Song Z, Zhu X, Wang H, Yang B., Free PMC Article | 03/6/2023 |
| ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells. | ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells.
Gao Z, Xu J, Fan Y, Zhang Z, Wang H, Qian M, Zhang P, Deng L, Shen J, Xue H, Zhao R, Zhou T, Guo X, Li G., Free PMC Article | 12/10/2022 |
| IFI16 Partners with KAP1 to Maintain Epstein-Barr Virus Latency. | IFI16 Partners with KAP1 to Maintain Epstein-Barr Virus Latency.
Xu H, Li X, Rousseau BA, Akinyemi IA, Frey TR, Zhou K, Droske LE, Mitchell JA, McIntosh MT, Bhaduri-McIntosh S., Free PMC Article | 09/24/2022 |
| IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer. | IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer.
Ong LT, Lee WC, Ma S, Oguz G, Niu Z, Bao Y, Yusuf M, Lee PL, Goh JY, Wang P, Yong KSM, Chen Q, Wang W, Ramasamy A, Hoon DSB, Ditzel HJ, Tan EY, Lee SC, Yu Q., Free PMC Article | 07/30/2022 |
| IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection. | IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection.
Griffante G, Hewelt-Belka W, Albano C, Gugliesi F, Pasquero S, Castillo Pacheco SF, Bajetto G, Porporato PE, Mina E, Vallino M, Krapp C, Jakobsen MR, Purdy J, von Einem J, Landolfo S, Dell'Oste V, Biolatti M., Free PMC Article | 07/2/2022 |
| HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration. | HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.
Liu C, Li L, Hou G, Lu Y, Gao M, Zhang L. | 06/25/2022 |
| The significance of interferon gamma inducible protein 16 (IFI16) expression in drug resistant ovarian cancer cell lines. | The significance of interferon gamma inducible protein 16 (IFI16) expression in drug resistant ovarian cancer cell lines.
Borucka J, Sterzyńska K, Kaźmierczak D, Świerczewska M, Nowacka M, Wojtowicz K, Klejewski A, Nowicki M, Zabel M, Ramlau R, Januchowski R. | 06/11/2022 |
| The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps. | The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps.
Antiochos B, Trejo-Zambrano D, Fenaroli P, Rosenberg A, Baer A, Garg A, Sohn J, Li J, Petri M, Goldman DW, Mecoli C, Casciola-Rosen L, Rosen A., Free PMC Article | 05/28/2022 |
| Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer. | Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E(2)-dependent growth of ER-positive breast cancer.
Ka NL, Lim GY, Kim SS, Hwang S, Han J, Lee YH, Lee MO., Free PMC Article | 05/28/2022 |
| IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ss pathway. | IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ß pathway.
Liu L, Xie S, Li C, Guo Y, Liu X, Zhao X, Li Q, Du W., Free PMC Article | 05/14/2022 |
| IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. | IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer.
Ka NL, Lim GY, Hwang S, Kim SS, Lee MO. | 02/19/2022 |
| The Role of Inflammasome Activation in Early HIV Infection. | The Role of Inflammasome Activation in Early HIV Infection.
Ekabe CJ, Clinton NA, Kehbila J, Franck NC., Free PMC Article | 02/12/2022 |
| Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. | Increased expression of IFI16 predicts adverse prognosis in multiple myeloma.
Huang W, Qian T, Huang Z, Liu Y, Cui L, Zhu P, Zhong Q, Zeng T, Fu L, Si C, Deng C. | 01/29/2022 |
| The role of cyclic GMP-AMP synthase and Interferon-I-inducible protein 16 as candidatebiomarkers of systemic lupus erythematosus. | The role of cyclic GMP-AMP synthase and Interferon-I-inducible protein 16 as candidatebiomarkers of systemic lupus erythematosus.
Fu Q, He Q, Dong Q, Xie J, Geng Y, Han H, Huang Y, Lu J, Zeng Z, Wang W, Chen K, Zhan X. | 12/25/2021 |
| IFI16 Isoforms with Cytoplasmic and Nuclear Locations Play Differential Roles in Recognizing Invaded DNA Viruses. | IFI16 Isoforms with Cytoplasmic and Nuclear Locations Play Differential Roles in Recognizing Invaded DNA Viruses.
Li D, Xie L, Qiao Z, Zhu J, Yao H, Qin Y, Yan Y, Chen Z, Ma F. | 12/4/2021 |
| IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. | IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection.
Jiang Z, Wei F, Zhang Y, Wang T, Gao W, Yu S, Sun H, Pu J, Sun Y, Wang M, Tong Q, Gao C, Chang KC, Liu J. | 09/25/2021 |