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    APOC3 apolipoprotein C3 [ Homo sapiens (human) ]

    Gene ID: 345, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    A novel lncRNA GM47544 modulates triglyceride metabolism by inducing ubiquitination-dependent protein degradation of APOC3.

    A novel lncRNA GM47544 modulates triglyceride metabolism by inducing ubiquitination-dependent protein degradation of APOC3.
    Xiao Q, Wang L, Wang J, Wang M, Wang DW, Ding H., Free PMC Article

    09/24/2024
    Apolipoprotein-CIII O-Glycosylation Is Associated with Micro- and Macrovascular Complications of Type 2 Diabetes.

    Apolipoprotein-CIII O-Glycosylation Is Associated with Micro- and Macrovascular Complications of Type 2 Diabetes.
    Naber A, Demus D, Slieker RC, Nicolardi S, Beulens JWJ, Elders PJM, Lieverse AG, Sijbrands EJG, 't Hart LM, Wuhrer M, van Hoek M., Free PMC Article

    06/10/2024
    Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance.

    Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance.
    Packard CJ, Pirillo A, Tsimikas S, Ference BA, Catapano AL., Free PMC Article

    02/22/2024
    Apolipoprotein C3 (ApoC3) facilitates NLRP3 mediated pyroptosis of macrophages through mitochondrial damage by accelerating of the interaction between SCIMP and SYK pathway in acute lung injury.

    Apolipoprotein C3 (ApoC3) facilitates NLRP3 mediated pyroptosis of macrophages through mitochondrial damage by accelerating of the interaction between SCIMP and SYK pathway in acute lung injury.
    Pu Z, Wang W, Xie H, Wang W.

    02/13/2024
    [The role of apolipoprotein C3 in the regulation of nonalcoholic fatty liver disease, glucose and lipid metabolism, and islet beta cell function].

    [The role of apolipoprotein C3 in the regulation of nonalcoholic fatty liver disease, glucose and lipid metabolism, and islet β cell function].
    Yan S, Ding ZY, Gao Y, Mao WJ, Cheng XY.

    01/30/2024
    Apolipoprotein C3: form begets function.

    Apolipoprotein C3: form begets function.
    Bornfeldt KE., Free PMC Article

    01/30/2024
    SP1 transcriptionally upregulates the expression of APOC3 in KGN cells to promote disease progression by regulating TLR2/NF-kappaB signalling pathway.

    SP1 transcriptionally upregulates the expression of APOC3 in KGN cells to promote disease progression by regulating TLR2/NF-κB signalling pathway.
    Qi N, Wen L, Li S, Li J, Feng C.

    11/1/2023
    [Association Between Apolipoprotein C-3 Sst Polymorphism and Serum Lipids in Patients With Gestational Diabetes Mellitus].

    [Association Between Apolipoprotein C-3 SstⅠ Polymorphism and Serum Lipids in Patients With Gestational Diabetes Mellitus].
    Tang F, Bai H, Guan L, Liu X, Fan P, Zhou M, Wu Y, Liu S, Wang Y, Li D., Free PMC Article

    10/28/2023
    Role of APOC3 3238C/G polymorphism in HIV-associated neurocognitive disorder.

    Role of APOC3 3238C/G polymorphism in HIV-associated neurocognitive disorder.
    Singh H, Dhotre K, Shyamveer, Namdev G, Mahajan SD, Parvez MK, Al-Dosari MS.

    05/17/2023
    APOC3 and ABCA1 variants in unusual combined hypolipidaemia showing premature peripheral vascular disease.

    APOC3 and ABCA1 variants in unusual combined hypolipidaemia showing premature peripheral vascular disease.
    Pos Z, Khedr M, Radvanszky J, Penesova A, Hekel R, Szemes T, Ranganath LR, Zatkova A.

    04/14/2023
    Investigation of associations between apolipoprotein A5 and C3 gene polymorphisms with plasma triglyceride and lipid levels.

    Investigation of associations between apolipoprotein A5 and C3 gene polymorphisms with plasma triglyceride and lipid levels.
    Taşkin E, Bağci H, Turan MK., Free PMC Article

    03/22/2023
    Apolipoprotein C3 is negatively associated with estrogen and mediates the protective effect of estrogen on hypertriglyceridemia in obese adults.

    Apolipoprotein C3 is negatively associated with estrogen and mediates the protective effect of estrogen on hypertriglyceridemia in obese adults.
    Li J, Sun H, Wang Y, Liu J, Wang G., Free PMC Article

    03/2/2023
    APOC-III: a Gatekeeper in Controlling Triglyceride Metabolism.

    APOC-III: a Gatekeeper in Controlling Triglyceride Metabolism.
    Giammanco A, Spina R, Cefalù AB, Averna M., Free PMC Article

    02/26/2023
    Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury.

    Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury.
    Schunk SJ, Hermann J, Sarakpi T, Triem S, Lellig M, Hahm E, Zewinger S, Schmit D, Becker E, Möllmann J, Lehrke M, Kramann R, Boor P, Lipp P, Laufs U, März W, Reiser J, Jankowski J, Fliser D, Speer T, Jankowski V., Free PMC Article

    02/11/2023
    Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function mutations.

    Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function mutations.
    Taskinen MR, Björnson E, Matikainen N, Söderlund S, Rämö J, Ainola MM, Hakkarainen A, Sihlbom C, Thorsell A, Andersson L, Bergh PO, Henricsson M, Romeo S, Adiels M, Ripatti S, Laakso M, Packard CJ, Borén J., Free PMC Article

    01/11/2023
    ENO1 Binds to ApoC3 and Impairs the Proliferation of T Cells via IL-8/STAT3 Pathway in OSCC.

    ENO1 Binds to ApoC3 and Impairs the Proliferation of T Cells via IL-8/STAT3 Pathway in OSCC.
    Wang J, Man Q, Zhong N, Wang H, Zhang C, Li S, Bu L, Liu B., Free PMC Article

    11/19/2022
    Apolipoprotein C3 and necrotic core volume are correlated but also associated with future cardiovascular events.

    Apolipoprotein C3 and necrotic core volume are correlated but also associated with future cardiovascular events.
    Ohwada T, Sakamoto T, Suzuki S, Sugawara Y, Sakamoto K, Ikeda A, Haga F, Sato T, Nakazato K, Takeishi Y, Watanabe K., Free PMC Article

    09/3/2022
    Apolipoprotein C3 Is Downregulated in Patients With Inflammatory Bowel Disease.

    Apolipoprotein C3 Is Downregulated in Patients With Inflammatory Bowel Disease.
    Hernández-Camba A, Carrillo-Palau M, Ramos L, de Armas-Rillo L, Vela M, Arranz L, González-Gay MÁ, Ferraz-Amaro I., Free PMC Article

    07/2/2022
    Apolipoprotein C-III is linked to the insulin resistance and beta-cell dysfunction that are present in rheumatoid arthritis.

    Apolipoprotein C-III is linked to the insulin resistance and beta-cell dysfunction that are present in rheumatoid arthritis.
    Martín-González C, Martín-Folgueras T, Quevedo-Abeledo JC, de Vera-González A, González-Delgado A, de Armas-Rillo L, González-Gay MÁ, Ferraz-Amaro I., Free PMC Article

    06/18/2022
    Apolipoprotein C-III in patients with systemic lupus erythematosus.

    Apolipoprotein C-III in patients with systemic lupus erythematosus.
    Martín-González C, Ferrer-Moure C, Carlos Quevedo-Abeledo J, de Vera-González A, González-Delgado A, Sánchez-Martín J, González-Gay MÁ, Ferraz-Amaro I., Free PMC Article

    05/14/2022
    The angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase axis is disrupted in patients with rheumatoid arthritis.

    The angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase axis is disrupted in patients with rheumatoid arthritis.
    de Armas-Rillo L, Quevedo-Abeledo JC, Hernández-Hernández V, de Vera-González A, González-Delgado A, García-Dopico JA, González-Gay MÁ, Ferraz-Amaro I., Free PMC Article

    05/14/2022
    J-shaped association between circulating apoC-III and cardiovascular mortality.

    J-shaped association between circulating apoC-III and cardiovascular mortality.
    Silbernagel G, Scharnagl H, Kleber ME, Hoffmann MM, Delgado GE, Stojakovic T, Gary T, Zeng L, Ritsch A, Zewinger S, Speer T, Schunkert H, Landmesser U, März W, Grammer TB.

    04/23/2022
    Triglyceride-rich lipoproteins, apolipoprotein C-III, angiopoietin-like protein 3, and cardiovascular events in older adults: Atherosclerosis Risk in Communities (ARIC) study.

    Triglyceride-rich lipoproteins, apolipoprotein C-III, angiopoietin-like protein 3, and cardiovascular events in older adults: Atherosclerosis Risk in Communities (ARIC) study.
    Hussain A, Sun C, Selvin E, Nambi V, Coresh J, Jia X, Ballantyne CM, Hoogeveen RC., Free PMC Article

    04/23/2022
    Apolipoprotein C-III predicts cardiovascular events and mortality in individuals with type 1 diabetes and albuminuria.

    Apolipoprotein C-III predicts cardiovascular events and mortality in individuals with type 1 diabetes and albuminuria.
    Jansson Sigfrids F, Stechemesser L, Dahlström EH, Forsblom CM, Harjutsalo V, Weitgasser R, Taskinen MR, Groop PH, FinnDiane Study Group., Free PMC Article

    04/2/2022
    Distribution of seven ApoC-III glycoforms in plasma, VLDL, IDL, LDL and HDL of healthy subjects.

    Distribution of seven ApoC-III glycoforms in plasma, VLDL, IDL, LDL and HDL of healthy subjects.
    Rodríguez M, Rehues P, Iranzo V, Mora J, Balsells C, Guardiola M, Ribalta J.

    03/5/2022
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