| IGF1R stimulates autophagy, enhances viability, and promotes insulin secretion in pancreatic beta cells in gestational diabetes mellitus by upregulating ATG7. | IGF1R stimulates autophagy, enhances viability, and promotes insulin secretion in pancreatic β cells in gestational diabetes mellitus by upregulating ATG7.
Liu Q, Han Y, Zhang M, Yang P, Xiang Y, Chen M, Xu F, Zhou X, Zheng D, Qin J. | 04/2/2024 |
| Exosomal miR-223 promotes ARDS by targeting insulin-like growth factor 1 receptor: A cell communication study. | Exosomal miR-223 promotes ARDS by targeting insulin-like growth factor 1 receptor: A cell communication study.
Li M, Zhuang L, Jiang T, Sun L. | 03/5/2024 |
| GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells. | GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells.
Gaal OI, Liu R, Marginean D, Badii M, Cabău G, Hotea I, Nica V, Colcear D, HINT Consortium, Pamfil C, Merriman TR, Rednic S, Popp RA, Crișan TO, Joosten LAB., Free PMC Article | 02/17/2024 |
| LncRNA JHDM1D-AS1 promotes osteogenic differentiation of periodontal ligament cells by targeting miR-532-5p to activate IGF1R signaling. | LncRNA JHDM1D-AS1 promotes osteogenic differentiation of periodontal ligament cells by targeting miR-532-5p to activate IGF1R signaling.
Zhong X, Wang H. | 02/15/2024 |
| The Insulin Receptor and Insulin like Growth Factor Receptor 5' UTRs Support Translation Initiation Independently of EIF4G1. | The Insulin Receptor and Insulin like Growth Factor Receptor 5' UTRs Support Translation Initiation Independently of EIF4G1.
Clark NK, Harris MT, Dahl WB, Knotts Z, Marr MT 2nd., | 02/15/2024 |
| microRNA-203 Targets Insulin-Like Growth Factor Receptor 1 to Inhibit Trophoblast Vascular Remodeling to Augment Preeclampsia. | microRNA-203 Targets Insulin-Like Growth Factor Receptor 1 to Inhibit Trophoblast Vascular Remodeling to Augment Preeclampsia.
Zhang L, Lv Y. | 02/8/2024 |
| Mapping respiratory syncytial virus fusion protein interactions with the receptor IGF1R and the impact of alanine-scanning mutagenesis on viral infection. | Mapping respiratory syncytial virus fusion protein interactions with the receptor IGF1R and the impact of alanine-scanning mutagenesis on viral infection.
Hayes RS, Oraby AK, Camargo C, Marchant DJ, Sagan SM. | 02/6/2024 |
| Insulin promotes growth in breast cancer cells through the type I IGF receptor in insulin receptor deficient cells. | Insulin promotes growth in breast cancer cells through the type I IGF receptor in insulin receptor deficient cells.
Monteiro M, Zhang X, Yee D., | 01/3/2024 |
| Association of IGF1R polymorphisms with kidney function-related traits. | Association of IGF1R polymorphisms with kidney function-related traits.
Park S, Jin HS. | 12/1/2023 |
| MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex. | MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex.
Jiang W, Yang X, Shi K, Zhang Y, Shi X, Wang J, Wang Y, Chenyan A, Shan J, Wang Y, Chang J, Chen R, Zhou T, Zhu Y, Yu Y, Li C, Li X. | 11/8/2023 |
| The HIFIA/LINC02913/IGF1R axis promotes the cell function of adipose-derived mesenchymal stem cells under hypoxia via activating the PI3K/AKT pathway. | The HIFIA/LINC02913/IGF1R axis promotes the cell function of adipose-derived mesenchymal stem cells under hypoxia via activating the PI3K/AKT pathway.
Xiong X, Yuan L, Yang K, Wang X., Free PMC Article | 11/1/2023 |
| The regulation of proliferation and apoptosis in hepatocellular carcinoma via insulin-like growth factor 1 receptor. | The regulation of proliferation and apoptosis in hepatocellular carcinoma via insulin-like growth factor 1 receptor.
Xu G, Chu J, Shi Y, Huang L, Fu J. | 11/1/2023 |
| IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia. | IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia.
Zheng K, Sha N, Hou G, Leng Z, Zhao Q, Zhang L, He L, Xu M, Jiang Y, Chen T., Free PMC Article | 10/10/2023 |
| Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway. | Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway.
Zhang P, Li H, Zhang A, Wang X, Song Q, Li Z, Wang W, Xu J, Hou Y, Zhang Y. | 10/5/2023 |
| EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis. | EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis.
Chakraborty S, Bhat AM, Mushtaq I, Luan H, Kalluchi A, Mirza S, Storck MD, Chaturvedi N, Lopez-Guerrero JA, Llombart-Bosch A, Machado I, Scotlandi K, Meza JL, Ghosal G, Coulter DW, Jordan Rowley M, Band V, Mohapatra BC, Band H., Free PMC Article | 09/8/2023 |
| Insulin-like growth factor-1 receptor crosstalk with integrins, cadherins, and the tumor microenvironment: sticking points in understanding IGF1R function in cancer. | Insulin-like growth factor-1 receptor crosstalk with integrins, cadherins, and the tumor microenvironment: sticking points in understanding IGF1R function in cancer.
Galifi CA, Wood TL. | 09/6/2023 |
| Insulin-like growth factor 1 receptor inhibits the proliferation of acute myeloid leukaemia cells via NK cell activation. | Insulin-like growth factor 1 receptor inhibits the proliferation of acute myeloid leukaemia cells via NK cell activation.
Wang S, Wang X, Shen K, Wei C, Li J. | 08/25/2023 |
| Obese Asthma Phenotype Is Associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p Modulating the IGF Axis. | Obese Asthma Phenotype Is Associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p Modulating the IGF Axis.
Gil-Martínez M, Lorente-Sorolla C, Rodrigo-Muñoz JM, Naharro S, García-de Castro Z, Sastre J, Valverde-Monge M, Quirce S, Caballero ML, Olaguibel JM, Del Pozo V., Free PMC Article | 08/19/2023 |
| IGF/IGF-1R signal pathway in pain: a promising therapeutic target. | IGF/IGF-1R signal pathway in pain: a promising therapeutic target.
Ma L, Zhao W, Huang S, Xu F, Wang Y, Deng D, Zhang T, Shu S, Chen X., Free PMC Article | 08/3/2023 |
| Circ-IGF1R Affects the Progression of Colorectal Cancer by Activating the miR-362-5p/HMGB3-Mediated Wnt/beta-Catenin Signal Pathway. | Circ-IGF1R Affects the Progression of Colorectal Cancer by Activating the miR-362-5p/HMGB3-Mediated Wnt/β-Catenin Signal Pathway.
Gao S, Zhang X, Bai W, Wang J, Jiang B. | 05/30/2023 |
| Circ_0005615 restrains the progression of multiple myeloma through modulating miR-331-3p and IGF1R regulatory cascade. | Circ_0005615 restrains the progression of multiple myeloma through modulating miR-331-3p and IGF1R regulatory cascade.
Zhang Q, Duan H, Yang W, Liu H, Tao X, Zhang Y., Free PMC Article | 05/24/2023 |
| The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells. | The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells.
Chan YT, Lin RJ, Wang YH, Hung TH, Huang Y, Yu J, Yu JC, Yu AL., Free PMC Article | 05/6/2023 |
| MiR-99b regulates cerebral ischemia neuronal injury through targeting IGF1R. | MiR-99b regulates cerebral ischemia neuronal injury through targeting IGF1R.
Qi D, Wang W, Zhang Y, Zhang T. | 03/16/2023 |
| Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling. | Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling.
Nagao H, Cai W, Brandão BB, Wewer Albrechtsen NJ, Steger M, Gattu AK, Pan H, Dreyfuss JM, Wunderlich FT, Mann M, Kahn CR., Free PMC Article | 03/6/2023 |
| IGF-1R down regulates the sensitivity of hepatocellular carcinoma to sorafenib through the PI3K / akt and RAS / raf / ERK signaling pathways. | IGF-1R down regulates the sensitivity of hepatocellular carcinoma to sorafenib through the PI3K / akt and RAS / raf / ERK signaling pathways.
Cai W, Ma Y, Song L, Cao N, Gao J, Zhou S, Tang X., Free PMC Article | 02/4/2023 |