| The protective effect of apolipoprotein H in paediatric sepsis. | The protective effect of apolipoprotein H in paediatric sepsis.
Yu Z, Xiao C, Liu R, Pi D, Jin B, Zou Z, Xu F., Free PMC Article | 02/8/2024 |
| Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis. | Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis.
Liu Y, Zhao Y, Liu Q, Li B, Daniel PV, Chen B, Wu Z., Free PMC Article | 01/30/2024 |
| The association of APOH and NCF1 polymorphisms on susceptibility to recurrent pregnancy loss in women with antiphospholipid syndrome. | The association of APOH and NCF1 polymorphisms on susceptibility to recurrent pregnancy loss in women with antiphospholipid syndrome.
Deng X, Sang Q, Zhang R, Mu J, Bao S., Free PMC Article | 09/6/2023 |
| Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk. | Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk.
Krilis M, Qi M, Ioannou Y, Zhang JY, Ahmadi Z, Wong JWH, Vlachoyiannopoulos PG, Moutsopoulos HM, Koike T, Sturgess AD, Chong BH, Krilis SA, Giannakopoulos B. | 02/12/2022 |
| Cardiolipin interacts with beta-2-glycoprotein I and forms an open conformation-Mechanisms analyzed using hydrogen/deuterium exchange. | Cardiolipin interacts with beta-2-glycoprotein I and forms an open conformation-Mechanisms analyzed using hydrogen/deuterium exchange.
Tang KT, Wu TY, Chen HH, Lin CC, Hsu YH., Free PMC Article | 12/25/2021 |
| An allosteric redox switch in domain V of beta2-glycoprotein I controls membrane binding and anti-domain I autoantibody recognition. | An allosteric redox switch in domain V of β(2)-glycoprotein I controls membrane binding and anti-domain I autoantibody recognition.
Kumar S, Chinnaraj M, Planer W, Zuo X, Macor P, Tedesco F, Pozzi N., Free PMC Article | 12/4/2021 |
| T Cell Proliferative Responses and IgG Antibodies to beta2GPI in Patients with Diabetes and Atherosclerosis. | T Cell Proliferative Responses and IgG Antibodies to β2GPI in Patients with Diabetes and Atherosclerosis.
Monjezi MR, Fouladseresht H, Farjadian S, Gharesi-Fard B, Khosropanah S, Doroudchi M. | 11/13/2021 |
| Apolipoprotein H drives hepatitis B surface antigen retention and endoplasmic reticulum stress during hepatitis B virus infection. | Apolipoprotein H drives hepatitis B surface antigen retention and endoplasmic reticulum stress during hepatitis B virus infection.
Liu Y, Maiers JL, Rui Y, Jiang X, Guleng B, Ren J. | 09/4/2021 |
| Tissue factor and human apolipoprotein H genetic variants and pro-inflammatory cytokines in systemic lupus erythematosus patients. | Tissue factor and human apolipoprotein H genetic variants and pro-inflammatory cytokines in systemic lupus erythematosus patients.
Wajda A, Sowińska A, Haładyj E, Stypińska B, Nałęcz-Janik J, Jagodziński PP, Majewski D, Olesińska M, Paradowska-Gorycka A. | 06/5/2021 |
| OxLDL/beta2GPI/antibeta2GPI Ab complex induces inflammatory activation via the TLR4/NFkappaB pathway in HUVECs. | OxLDL/β2GPI/anti‑β2GPI Ab complex induces inflammatory activation via the TLR4/NF‑κB pathway in HUVECs.
Zhang G, Cai Q, Zhou H, He C, Chen Y, Zhang P, Wang T, Xu L, Yan J., Free PMC Article | 05/8/2021 |
| Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report. | Genome-Wide Association Study Highlights APOH as a Novel Locus for Lipoprotein(a) Levels-Brief Report.
Hoekstra M, Chen HY, Rong J, Dufresne L, Yao J, Guo X, Tsai MY, Tsimikas S, Post WS, Vasan RS, Rotter JI, Larson MG, Thanassoulis G, Engert JC., Free PMC Article | 02/6/2021 |
| The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome. | The J-elongated conformation of β(2)-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.
Ruben E, Planer W, Chinnaraj M, Chen Z, Zuo X, Pengo V, De Filippis V, Alluri RK, McCrae KR, Macor P, Tedesco F, Pozzi N., Free PMC Article | 01/16/2021 |
| Free Thiol beta2-GPI (beta-2-Glycoprotein-I) Provides a Link Between Inflammation and Oxidative Stress in Atherosclerotic Coronary Artery Disease. | Free Thiol β2-GPI (β-2-Glycoprotein-I) Provides a Link Between Inflammation and Oxidative Stress in Atherosclerotic Coronary Artery Disease.
Weaver JC, Ullah I, Qi M, Giannakopoulos B, Rye KA, Kockx M, Kritharides L, Krilis SA. | 12/19/2020 |
| The IgA Isotype of Anti-beta2 Glycoprotein I Antibodies Recognizes Epitopes in Domains 3, 4, and 5 That Are Located in a Lateral Zone of the Molecule (L-Shaped). | The IgA Isotype of Anti-β2 Glycoprotein I Antibodies Recognizes Epitopes in Domains 3, 4, and 5 That Are Located in a Lateral Zone of the Molecule (L-Shaped).
Serrano M, Martinez-Flores JA, Norman GL, Naranjo L, Morales JM, Serrano A., Free PMC Article | 10/3/2020 |
| New insight into antiphospholipid syndrome: antibodies to beta2glycoprotein I-domain 5 fail to induce thrombi in rats. | New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats.
Durigutto P, Grossi C, Borghi MO, Macor P, Pregnolato F, Raschi E, Myers MP, de Groot PG, Meroni PL, Tedesco F., Free PMC Article | 05/9/2020 |
| beta2GPI/abeta2GPI can inhibit the phagocytosis of oxLDL and CD36 expression in macrophages, which is linked to the function of TLR4. | [The β2GPI/aβ2GPI inhibits phagocytosis of oxidized low-density lipoprotein in THP-1 macrophages via activating TLR4].
He C, Zhou H, Zhang G, Chen Y, Zhang P, Wang R, Wu Q, Yao Y, Kuang M. | 07/20/2019 |
| Our study delineates the role of beta2GPI in murine septicaemia though not in murine sepsis, however our preliminary patient data suggest that examining the role of beta2GPI in sepsis models in the future is a reasonable avenue to pursue. | Βeta 2-glycoprotein I protects mice against gram-negative septicaemia in a sexually dimorphic manner.
El-Assaad F, Qi M, Gordon AK, Qi J, Dong S, Passam F, Weaver JC, Giannakopoulos B, Krilis SA., Free PMC Article | 03/9/2019 |
| This study aimed to explore the mechanism of a novel mutation (p.Lys38Glu) in apolipoprotein H (APOH) gene causing hereditary beta2-glycoprotein I (beta2GPI) deficiency and thrombosis in a proband with thrombophilia. | Thrombophilia Caused by Beta2-Glycoprotein I Deficiency: In Vitro Study of a Rare Mutation in APOH Gene.
Zhang XP, Zeng W, Liu H, Tang L, Wang QY, Cheng ZP, Wu YY, Hu B, Shi W, Hu Y. | 11/3/2018 |
| Data suggest alpha-1-antitrypsin (A1AT) and APOH (beta-2-glycoprotein-1) could represent promising markers for renal carcinogenesis in Von Hippel-Lindau disease (VHLD) patients. | Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel-Lindau patients.
Mandili G, Notarpietro A, Khadjavi A, Allasia M, Battaglia A, Lucatello B, Frea B, Turrini F, Novelli F, Giribaldi G, Destefanis P. | 08/25/2018 |
| Suggest that anti-beta2 GPI antibodies bind to beta2 GPI-PS complexes expressed on microparticles. Consequent loss of beta2 GPI-PS expression on MPs may impair scavenging and contribute to the accumulation of circulating PS-negative MPs, a possible source of autoantigens in systemic lupus erythematosus. | Altered β(2) -glycoprotein I expression on microparticles in the presence of antiphospholipid antibodies.
Mobarrez F, Gunnarsson I, Svenungsson E. | 07/21/2018 |
| the data revealed that reduced beta2GPI exerts protective effects from glucoseinduced injury in human umbilical cord vein endothelial cells. | Effects of reduced β2 glycoprotein I on high glucose‑induced cell death in HUVECs.
Zhang JY, Ma J, Yu P, Tang GJ, Li CJ, Yu DM, Zhang QM. | 05/19/2018 |
| Data suggest that, in patients with anti-GPIIb/IIIa-mediated immune thrombocytopenia, diminished plasma levels of beta2-GPI are linked to enhanced complement activation. | Diminished expression of β2-GPI is associated with a reduced ability to mitigate complement activation in anti-GPIIb/IIIa-mediated immune thrombocytopenia.
Zhu X, Zhang J, Wang Q, Fu H, Chang Y, Kong Y, Lv M, Xu L, Liu K, Huang X, Zhang X. | 03/10/2018 |
| The aim of this study was to assess clinical utility of the anti-Domain 1 B2GP1 antibodies in the diagnosis and risk stratification of antiphospholipid syndrome. Anti-Domain 1 test does not add accuracy in predicting Antiphospholipid syndrome thrombotic complications on the top of accuracy offered by classic tests. | Clinical significance of anti-domain 1 β2-glycoprotein I antibodies in antiphospholipid syndrome.
Iwaniec T, Kaczor MP, Celińska-Löwenhoff M, Polański S, Musiał J. | 02/17/2018 |
| we have demonstrated a pathogenic role for aPL containing samples, mediated via aPL-2bGPI interactions, resulting in activation of the pro-apoptotic p38 MAPK pathway. | Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK.
Bourke LT, McDonnell T, McCormick J, Pericleous C, Ripoll VM, Giles I, Rahman A, Stephanou A, Ioannou Y., Free PMC Article | 10/28/2017 |
| Pretransplant IgA-aB2GP1 was the main risk factor for graft thrombosis and early graft loss after renal transplantation. | The Presence of Pretransplant Antiphospholipid Antibodies IgA Anti-β-2-Glycoprotein I as a Predictor of Graft Thrombosis After Renal Transplantation.
Morales JM, Serrano M, Martínez-Flores JA, Pérez D, Castro MJ, Sánchez E, García F, Rodríguez-Antolín A, Alonso M, Gutierrez E, Morales E, Praga M, González E, Andrés A, Paz-Artal E, Martínez MA, Serrano A. | 05/27/2017 |