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    IL1A interleukin 1 alpha [ Homo sapiens (human) ]

    Gene ID: 3552, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Interleukin-1alpha inhibits transforming growth factor-beta1 and beta2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair.

    Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair.
    Usman K, Fouadi M, Nwozor KO, Aminazadeh F, Nair P, Luo H, Sin DD, Osei ET, Hackett TL.

    08/22/2024
    Interleukin-1 increases SERPINE1 expression in human granulosa-lutein cell via P50/P52 signaling pathways.

    Interleukin-1 increases SERPINE1 expression in human granulosa-lutein cell via P50/P52 signaling pathways.
    Xiang Y, Liu S, Wan S, Chen Q, Song Y, Feng G, Zhang X, Bai L, Zhu Y.

    07/15/2024
    Processing of angiocrine alarmin IL-1alpha in endothelial cells promotes lung and liver fibrosis.

    Processing of angiocrine alarmin IL-1α in endothelial cells promotes lung and liver fibrosis.
    Zhang C, Ma J, Zhang X, Zhou D, Cao Z, Qiao L, Chen G, Yang L, Ding BS.

    06/10/2024
    Association of genetic polymorphism of interleukin 1-alpha and interleukin 1-beta with external apical root resorption in orthodontic patients.

    Association of genetic polymorphism of interleukin 1-alpha and interleukin 1-beta with external apical root resorption in orthodontic patients.
    Chauhan J, Sharma P, Shetty D, Kumar P, Jain S, Suroliya V, Garg P.

    05/24/2024
    Correlations of IL-1 and IL-6 Gene polymorphisms with hypertrophic cardiomyopathy.

    Correlations of IL-1 and IL-6 Gene polymorphisms with hypertrophic cardiomyopathy.
    Liu N, Liu C, Wu Y, Li H.

    05/21/2024
    Serum Interleukin-1 Levels Are Associated with Intracranial Aneurysm Instability.

    Serum Interleukin-1 Levels Are Associated with Intracranial Aneurysm Instability.
    Liu Q, Liu P, Zhang Y, Mossa-Basha M, Hasan DM, Li J, Zhu C, Wang S.

    02/26/2024
    Group B streptococcus induces cellular senescence in human amnion epithelial cells through a partial interleukin-1-mediated mechanism.

    Group B streptococcus induces cellular senescence in human amnion epithelial cells through a partial interleukin-1-mediated mechanism.
    Park HR, Hogan KA, Harris SM, Chames MC, Loch-Caruso R.,

    02/22/2024
    Analysis of the effects of importin alpha1 on the nuclear translocation of IL-1alpha in HeLa cells.

    Analysis of the effects of importin α1 on the nuclear translocation of IL-1α in HeLa cells.
    Yamada A, Wake K, Imaoka S, Motoyoshi M, Yamamoto T, Asano M., Free PMC Article

    02/16/2024
    IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1alpha.

    IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1α.
    Azumi Y, Koma YI, Tsukamoto S, Kitamura Y, Ishihara N, Yamanaka K, Nakanishi T, Miyako S, Urakami S, Tanigawa K, Kodama T, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H., Free PMC Article

    11/28/2023
    Role of ErbB and IL-1 signaling pathways in the dermonecrotic lesion induced by Loxosceles sphingomyelinases D.

    Role of ErbB and IL-1 signaling pathways in the dermonecrotic lesion induced by Loxosceles sphingomyelinases D.
    Pinto BF, Lopes PH, Trufen CEM, Ching ATC, De Azevedo ILMJ, Nishiyama MY Jr, Pohl PC, Tambourgi DV.

    11/7/2023
    Serum interleukin-1 is a new biomarker to predict the risk of rebleeding of ruptured intracranial aneurysm after admission.

    Serum interleukin-1 is a new biomarker to predict the risk of rebleeding of ruptured intracranial aneurysm after admission.
    Wen Z, Liu Q, Jiang P, Zhu C, Li J, Wu J, Wang S, Ning B.

    05/28/2023
    Tear levels of IL-7, IL-1alpha, and IL-1beta may differentiate between IgG4-related disease and Sjogren's syndrome.

    Tear levels of IL-7, IL-1α, and IL-1β may differentiate between IgG4-related disease and Sjögren's syndrome.
    Martín-Nares E, Hernández-Molina G, Lima G, Hernández-Ramírez DF, Chan-Campos I, Saavedra-González V, Llorente L.

    03/30/2023
    Interleukin 1alpha and interleukin 18 in patients with vitiligo - Results of a case-control study.

    Interleukin 1α and interleukin 18 in patients with vitiligo - Results of a case-control study.
    Nieradko-Iwanicka B, Przybylska D, Borzęcki A.

    03/8/2023
    Association between Polymorphism of Genes IL-1A, NFKB1, PAR1, TP53, and UCP2 and Susceptibility to Non-Small Cell Lung Cancer in the Brazilian Amazon.

    Association between Polymorphism of Genes IL-1A, NFKB1, PAR1, TP53, and UCP2 and Susceptibility to Non-Small Cell Lung Cancer in the Brazilian Amazon.
    Pereira EEB, Modesto AAC, Fernandes BM, Burbano RMR, Assumpção PP, Fernandes MR, Guerreiro JF, Santos SEBD, Santos NPCD., Free PMC Article

    03/3/2023
    The common IL1A single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukin-1alpha release from human blood cells.

    The common IL1A single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukin-1α release from human blood cells.
    Wiggins KA, Pyrillou K, Humphry M, Butterworth AS, Clarke MC.

    02/24/2023
    Increased IL-1alpha expression in chronic rhinosinusitis with nasal polyps.

    Increased IL-1α expression in chronic rhinosinusitis with nasal polyps.
    Cao Y, Hu X, Zhou C, Zhao K, Zheng Y, Jiang W, Wang D, Li H., Free PMC Article

    02/11/2023
    Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses.

    Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses.
    Llibre A, Smith N, Rouilly V, Musvosvi M, Nemes E, Posseme C, Mabwe S, Charbit B, Mbandi SK, Filander E, Africa H, Saint-André V, Bondet V, Bost P, Mulenga H, Bilek N, Albert ML, Scriba TJ, Duffy D., Free PMC Article

    01/14/2023
    IL-1 Superfamily Member (IL-1A, IL-1B and IL-18) Genetic Variants Influence Susceptibility and Clinical Course of Mediterranean Spotter Fever.

    IL-1 Superfamily Member (IL-1A, IL-1B and IL-18) Genetic Variants Influence Susceptibility and Clinical Course of Mediterranean Spotter Fever.
    Scola L, Pilato G, Giarratana RM, Sanfilippo GL, Lio D, Colomba C, Giammanco GM., Free PMC Article

    01/14/2023
    Interleukin-1alpha and tumor necrosis factor alpha as an inducer for reactive-oxygen-species-mediated NOD-like receptor protein 1/NOD-like receptor protein 3 inflammasome activation in mononuclear blood cells from individuals with chronic insomnia disorder.

    Interleukin-1α and tumor necrosis factor α as an inducer for reactive-oxygen-species-mediated NOD-like receptor protein 1/NOD-like receptor protein 3 inflammasome activation in mononuclear blood cells from individuals with chronic insomnia disorder.
    Aghelan Z, Karima S, Khazaie H, Abtahi SH, Farokhi AR, Rostampour M, Bahrehmand F, Khodarahmi R.

    11/5/2022
    Gene locus polymorphisms and expression levels of interleukin-1 in lumbar disc disease: A MOOSE-compliant meta-analysis and immunohistochemical study.

    Gene locus polymorphisms and expression levels of interleukin-1 in lumbar disc disease: A MOOSE-compliant meta-analysis and immunohistochemical study.
    Yang K, Xiao Q, Zhang R, Meng D, Wang J, Wei Q, Jiang H., Free PMC Article

    11/5/2022
    The Association of Inflammatory Markers, IL-1alpha and TGF-beta, with Dietary Insulin Load and Dietary Insulin Index in Overweight and Obese Women with Healthy and Unhealthy Metabolic Phenotypes: A Cross-Sectional Study.

    The Association of Inflammatory Markers, IL-1α and TGF-β, with Dietary Insulin Load and Dietary Insulin Index in Overweight and Obese Women with Healthy and Unhealthy Metabolic Phenotypes: A Cross-Sectional Study.
    Noori S, Mirzababaei A, Shiraseb F, Bagheri R, Clark CCT, Wong A, Suzuki K, Mirzaei K., Free PMC Article

    11/5/2022
    Analysis of Chitinase-3-Like Protein 1, IL-1-Alpha, and IL-6 as Novel Inflammatory Biomarkers for COVID-19.

    Analysis of Chitinase-3-Like Protein 1, IL-1-Alpha, and IL-6 as Novel Inflammatory Biomarkers for COVID-19.
    Parlak E, Laloğlu E.

    10/29/2022
    Investigation of EGF, IL1-alpha and IL-6 levels and selected hematological parameters (NLR, MPV) in patients with the chronic cholesteatomatous otitis media.

    Investigation of EGF, IL1-α and IL-6 levels and selected hematological parameters (NLR, MPV) in patients with the chronic cholesteatomatous otitis media.
    Çandar T, Baklaci D, Bilgin E, Erdem D, Dalgıç M.

    10/1/2022
    Comparison of Interleukin-1 Ligand Expression by Human Papilloma Virus Status in HNSCCs.

    Comparison of Interleukin-1 Ligand Expression by Human Papilloma Virus Status in HNSCCs.
    Khan IN, Gibson-Corley KN, Coppock JD, Simons AL., Free PMC Article

    09/3/2022
    Relationship Between IL1 Gene Polymorphism and Susceptibility to Ankylosing Spondylitis: An Updated and Supplemented Meta-Analysis.

    Relationship Between IL1 Gene Polymorphism and Susceptibility to Ankylosing Spondylitis: An Updated and Supplemented Meta-Analysis.
    Gao M, Li T, Song Z, Wang X, Zhang X, Liu W.

    07/30/2022
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