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    AQP2 aquaporin 2 [ Homo sapiens (human) ]

    Gene ID: 359, updated on 15-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Proteomics and AQP2 regulation.

    Proteomics and AQP2 regulation.
    Yang CR, Park E, Chen L, Datta A, Chou CL, Knepper MA., Free PMC Article

    07/11/2024
    Novel signalling pathways in nephrogenic syndrome of inappropriate antidiuresis: functional implication of site-specific AQP2 phosphorylation.

    Novel signalling pathways in nephrogenic syndrome of inappropriate antidiuresis: functional implication of site-specific AQP2 phosphorylation.
    Venneri M, Vezzi V, Di Mise A, Ranieri M, Centrone M, Tamma G, Nejsum LN, Valenti G.

    07/11/2024
    Many kinases for controlling the water channel aquaporin-2.

    Many kinases for controlling the water channel aquaporin-2.
    Kharin A, Klussmann E.

    07/11/2024
    Ionic Liquid Gating Induces Anomalous Permeation through Membrane Channel Proteins.

    Ionic Liquid Gating Induces Anomalous Permeation through Membrane Channel Proteins.
    Liu J, Wang Y, Gao B, Zhang K, Li H, Ren J, Huo F, Zhao B, Zhang L, Zhang S, He H.

    06/27/2024
    Diurnal rhythm of urinary aquaporin-2 in children with primary monosymptomatic nocturnal enuresis.

    Diurnal rhythm of urinary aquaporin-2 in children with primary monosymptomatic nocturnal enuresis.
    Abdelhamid N, Almawla MAA, Wahby AA, Ismail M, Elmikaty HA, Hamed HM, Ashmawy I, Abdelraoaf BM, Abdelhamid EM, Salam HM., Free PMC Article

    06/6/2024
    Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus.

    Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus.
    Hagströmer CJ, Hyld Steffen J, Kreida S, Al-Jubair T, Frick A, Gourdon P, Törnroth-Horsefield S., Free PMC Article

    09/8/2023
    Dynamics and energetics of water transport through aquaporin mutants causing nephrogenic diabetes insipidus (NDI): A molecular dynamics study.

    Dynamics and energetics of water transport through aquaporin mutants causing nephrogenic diabetes insipidus (NDI): A molecular dynamics study.
    Hadidi H, Kamali R, Binesh A.

    03/19/2022
    Reduced urinary release of AQP1- and AQP2-bearing extracellular vesicles in patients with advanced chronic kidney disease.

    Reduced urinary release of AQP1- and AQP2-bearing extracellular vesicles in patients with advanced chronic kidney disease.
    Oshikawa-Hori S, Yokota-Ikeda N, Sonoda H, Sasaki Y, Ikeda M., Free PMC Article

    02/26/2022
    Investigation of the aquaporin-2 gating mechanism with molecular dynamics simulations.

    Investigation of the aquaporin-2 gating mechanism with molecular dynamics simulations.
    Hadidi H, Kamali R, Binesh A.

    01/8/2022
    Novel AQP2 Mutations and Clinical Characteristics in Seven Chinese Families With Congenital Nephrogenic Diabetes Insipidus.

    Novel AQP2 Mutations and Clinical Characteristics in Seven Chinese Families With Congenital Nephrogenic Diabetes Insipidus.
    Li Q, Tian D, Cen J, Duan L, Xia W., Free PMC Article

    12/25/2021
    miR-34b-5p promotes renal cell inflammation and apoptosis by inhibiting aquaporin-2 in sepsis-induced acute kidney injury.

    miR-34b-5p promotes renal cell inflammation and apoptosis by inhibiting aquaporin-2 in sepsis-induced acute kidney injury.
    Zheng C, Wu D, Shi S, Wang L., Free PMC Article

    10/9/2021
    Altered Iris Aquaporin Expression and Aqueous Humor Osmolality in Glaucoma.

    Altered Iris Aquaporin Expression and Aqueous Humor Osmolality in Glaucoma.
    Huang OS, Seet LF, Ho HW, Chu SW, Narayanaswamy A, Perera SA, Husain R, Aung T, Wong TT., Free PMC Article

    07/24/2021
    Seasonal rhythms of vasopressin release and aquaporin-2 excretion assure appropriate water conservation in humans.

    Seasonal rhythms of vasopressin release and aquaporin-2 excretion assure appropriate water conservation in humans.
    Goswami N, Di Mise A, Centrone M, Russo A, Ranieri M, Reichmuth J, Brix B, De Santo NG, Sasso FC, Tamma G, Valenti G., Free PMC Article

    07/10/2021
    AQP2: Mutations Associated with Congenital Nephrogenic Diabetes Insipidus and Regulation by Post-Translational Modifications and Protein-Protein Interactions.

    AQP2: Mutations Associated with Congenital Nephrogenic Diabetes Insipidus and Regulation by Post-Translational Modifications and Protein-Protein Interactions.
    Gao C, Higgins PJ, Zhang W., Free PMC Article

    06/19/2021
    Differential expression and inhibitory effects of aquaporins on the development of adenomyosis.

    Differential expression and inhibitory effects of aquaporins on the development of adenomyosis.
    Jia L, Liu Y, Han Y, Zhou X, Wang F., Free PMC Article

    05/1/2021
    Phosphorylation of human AQP2 and its role in trafficking.

    Phosphorylation of human AQP2 and its role in trafficking.
    Törnroth-Horsefield S.

    04/3/2021
    Calcium sensing receptor exerts a negative regulatory action toward vasopressin-induced aquaporin-2 expression and trafficking in renal collecting duct.

    Calcium sensing receptor exerts a negative regulatory action toward vasopressin-induced aquaporin-2 expression and trafficking in renal collecting duct.
    Ranieri M, Di Mise A, Tamma G, Valenti G.

    04/3/2021
    Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP.

    Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP.
    Dema A, Faust D, Lazarow K, Wippich M, Neuenschwander M, Zühlke K, Geelhaar A, Pallien T, Hallscheidt E, Eichhorst J, Wiesner B, Černecká H, Popp O, Mertins P, Dittmar G, von Kries JP, Klussmann E., Free PMC Article

    03/13/2021
    The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation.

    The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation.
    Ranieri M, Venneri M, Pellegrino T, Centrone M, Di Mise A, Cotecchia S, Tamma G, Valenti G., Free PMC Article

    03/6/2021
    Decreased Excretion of Urinary Exosomal Aquaporin-2 in a Puromycin Aminonucleoside-Induced Nephrotic Syndrome Model.

    Decreased Excretion of Urinary Exosomal Aquaporin-2 in a Puromycin Aminonucleoside-Induced Nephrotic Syndrome Model.
    Abdeen A, Sonoda H, Kaito A, Oshikawa-Hori S, Fujimoto N, Ikeda M., Free PMC Article

    02/20/2021
    A female with X-linked Nephrogenic diabetes insipidus in a family with inherited central diabetes Insipidus: Case report and review of the literature.

    A female with X-linked Nephrogenic diabetes insipidus in a family with inherited central diabetes Insipidus: Case report and review of the literature.
    Ding C, Beetz R, Rittner G, Bartsch O.

    01/16/2021
    Perioperative urinary excretion of aquaporin-2 dependent upon vasopressin in cardiac surgery.

    Perioperative urinary excretion of aquaporin-2 dependent upon vasopressin in cardiac surgery.
    Fujii M, Amitani R, Bessho R.

    12/12/2020
    expression lost from collecting ducts in cholemic nephropathy

    Cholemic Nephropathy Causes Acute Kidney Injury and Is Accompanied by Loss of Aquaporin 2 in Collecting Ducts.
    Bräsen JH, Mederacke YS, Schmitz J, Diahovets K, Khalifa A, Hartleben B, Person F, Wiech T, Steenbergen E, Großhennig A, Manns MP, Schmitt R, Mederacke I.

    06/20/2020
    A structural model of the AQP2-LIP5 complex, giving the very first structural insight into how membrane proteins are recruited to multivesicular bodies inner vesicles.

    Structural Insights into AQP2 Targeting to Multivesicular Bodies.
    Roche JV, Nesverova V, Olsson C, Deen PM, Törnroth-Horsefield S., Free PMC Article

    04/4/2020
    AQP2 expression levels in human endometrium may be mediated by estrogen.

    AQP2 is regulated by estradiol in human endometrium and is associated with spheroid attachment in vitro.
    He R, Han W, Hu Y, Chen X, Hu X, Zhu Y.

    12/14/2019
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