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    IL15 interleukin 15 [ Homo sapiens (human) ]

    Gene ID: 3600, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    IL-15 gene mutation as a molecular risk factor in acute lymphoid leukemia.

    IL-15 gene mutation as a molecular risk factor in acute lymphoid leukemia.
    Mohammed SI, Hassan KM, Azeez DM, Qadir FA, Salihi AB.

    06/6/2024
    Interleukin-15 is a hair follicle immune privilege guardian.

    Interleukin-15 is a hair follicle immune privilege guardian.
    Suzuki T, Chéret J, Scala FD, Rajabi-Estarabadi A, Akhundlu A, Demetrius DL, Gherardini J, Keren A, Harries M, Rodriguez-Feliz J, Epstein G, Lee W, Purba T, Gilhar A, Paus R.

    05/31/2024
    Immunocytokines with target cell-restricted IL-15 activity for treatment of B cell malignancies.

    Immunocytokines with target cell-restricted IL-15 activity for treatment of B cell malignancies.
    Zekri L, Hagelstein I, Märklin M, Klimovich B, Christie M, Lindner C, Kämereit S, Prakash N, Müller S, Stotz S, Maurer A, Greve C, Schmied B, Atar D, Rammensee HG, Jung G, Salih HR.

    03/11/2024
    Abnormal M1 polarization of placental macrophage induced by IL-15/STAT5 activation in VVC may lead to adverse pregnancy outcomes.

    Abnormal M1 polarization of placental macrophage induced by IL-15/STAT5 activation in VVC may lead to adverse pregnancy outcomes.
    Zhang Y, Zhao L, Wu A, Lin P, Fan J, Chen J, Wang X, Zeng X.

    02/1/2024
    Investigating the interplay of hematological parameters, CD markers, genetic polymorphisms, and database mutations in the IL15 gene in acute myeloid leukemia patients.

    Investigating the interplay of hematological parameters, CD markers, genetic polymorphisms, and database mutations in the IL15 gene in acute myeloid leukemia patients.
    Azeez DM, Mohammed SI, M Hassan K, Salihi A.

    11/3/2023
    The roles of different forms of IL-15 in human melanoma progression.

    The roles of different forms of IL-15 in human melanoma progression.
    Di Matteo S, Munari E, Fiore PF, Santopolo S, Sampaoli C, Pelosi A, Chouaib S, Tumino N, Vacca P, Mariotti FR, Ebert S, Machwirth M, Haas D, Pezzullo M, Pietra G, Grottoli M, Buart S, Mortier E, Maggi E, Moretta L, Caruana I, Azzarone B., Free PMC Article

    10/20/2023
    The role of interleukin-15 in the development and treatment of hematological malignancies.

    The role of interleukin-15 in the development and treatment of hematological malignancies.
    Sindaco P, Pandey H, Isabelle C, Chakravarti N, Brammer JE, Porcu P, Mishra A., Free PMC Article

    05/18/2023
    Myc controls NK cell development, IL-15-driven expansion, and translational machinery.

    Myc controls NK cell development, IL-15-driven expansion, and translational machinery.
    Khameneh HJ, Fonta N, Zenobi A, Niogret C, Ventura P, Guerra C, Kwee I, Rinaldi A, Pecoraro M, Geiger R, Cavalli A, Bertoni F, Vivier E, Trumpp A, Guarda G., Free PMC Article

    05/8/2023
    Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology.

    Counteracting Interleukin-15 to Elucidate Its Modes of Action in Physiology and Pathology.
    Mortier E, Maillasson M, Quéméner A.

    01/28/2023
    IL-15 induced bystander activation of CD8[+] T cells may mediate endothelium injury through NKG2D in Hantaan virus infection.

    IL-15 induced bystander activation of CD8(+) T cells may mediate endothelium injury through NKG2D in Hantaan virus infection.
    Zhang X, Zhang Y, Liu H, Tang K, Zhang C, Wang M, Xue M, Jia X, Hu H, Li N, Zhuang R, Jin B, Zhang F, Zhang Y, Ma Y., Free PMC Article

    01/14/2023
    The effects of ageing, BMI and physical activity on blood IL-15 levels: A systematic review and meta-analyses.

    The effects of ageing, BMI and physical activity on blood IL-15 levels: A systematic review and meta-analyses.
    Prado GHJD, Sardeli AV, Lord JM, Cavaglieri CR.

    10/8/2022
    Circulating myokines IL-6, IL-15 and FGF21 response to training is altered by exercise type but not by menopause in women with obesity.

    Circulating myokines IL-6, IL-15 and FGF21 response to training is altered by exercise type but not by menopause in women with obesity.
    Pérez-López A, Gonzalo-Encabo P, Pérez-Köhler B, García-Honduvilla N, Valadés D.

    09/24/2022
    Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies.

    Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies.
    Kansler ER, Dadi S, Krishna C, Nixon BG, Stamatiades EG, Liu M, Kuo F, Zhang J, Zhang X, Capistrano K, Blum KA, Weiss K, Kedl RM, Cui G, Ikuta K, Chan TA, Leslie CS, Hakimi AA, Li MO., Free PMC Article

    06/11/2022
    Opposing roles for sMAdCAM and IL-15 in COVID-19 associated cellular immune pathology.

    Opposing roles for sMAdCAM and IL-15 in COVID-19 associated cellular immune pathology.
    Singh AK, Kasarpalkar N, Bhowmick S, Paradkar G, Talreja M, Shah K, Tiwari A, Palav H, Kaginkar S, Kulkarni R, Patil A, Kalsurkar V, Agrawal S, Shastri J, Dere R, Bharmal R, Mahale SD, Bhor VM, Patel V., Free PMC Article

    05/28/2022
    Autophagy-Mediated Activation of Mucosal-Associated Invariant T Cells Driven by Mesenchymal Stem Cell-Derived IL-15.

    Autophagy-Mediated Activation of Mucosal-Associated Invariant T Cells Driven by Mesenchymal Stem Cell-Derived IL-15.
    Ye G, Wang P, Xie Z, Cao Q, Li J, Zheng G, Wang S, Li M, Liu W, Cen S, Li Z, Yu W, Wu Y, Shen H., Free PMC Article

    03/5/2022
    IL-15 and IL-23 synergize to trigger Th17 response by CLA(+) T cells in psoriasis.

    IL-15 and IL-23 synergize to trigger Th17 response by CLA(+) T cells in psoriasis.
    de Jesús-Gil C, Ruiz-Romeu E, Ferran M, Sagristà M, Chiriac A, García P, Celada A, Pujol RM, Santamaria-Babí LF.

    02/19/2022
    IL-15 enhances CCR5-mediated migration of memory CD8(+) T cells by upregulating CCR5 expression in the absence of TCR stimulation.

    IL-15 enhances CCR5-mediated migration of memory CD8(+) T cells by upregulating CCR5 expression in the absence of TCR stimulation.
    Seo IH, Eun HS, Kim JK, Lee H, Jeong S, Choi SJ, Lee J, Lee BS, Kim SH, Rou WS, Lee DH, Kim W, Park SH, Shin EC.

    02/12/2022
    IL-15 Gene Polymorphism in Celiac Disease Patients and Their Siblings.

    IL-15 Gene Polymorphism in Celiac Disease Patients and Their Siblings.
    Kara Y, Eren M, Arslan S, Çilingir O., Free PMC Article

    01/29/2022
    Expansion of invariant natural killer T cells from systemic lupus erythematosus patients by alpha-Galactosylceramide and IL-15.

    Expansion of invariant natural killer T cells from systemic lupus erythematosus patients by alpha-Galactosylceramide and IL-15.
    Hsu CY, Chueh YS, Kuo ML, Lee PT, Hsiao HS, Huang JL, Lin SJ., Free PMC Article

    01/15/2022
    Gut Bacteria Induce Granzyme B Expression in Human Colonic ILC3s In Vitro in an IL-15-Dependent Manner.

    Gut Bacteria Induce Granzyme B Expression in Human Colonic ILC3s In Vitro in an IL-15-Dependent Manner.
    Castleman MJ, Dillon SM, Thompson TA, Santiago ML, McCarter MD, Barker E, Wilson CC., Free PMC Article

    01/8/2022
    Interleukin-15 in Outcomes of Pregnancy.

    Interleukin-15 in Outcomes of Pregnancy.
    Gordon SM., Free PMC Article

    01/1/2022
    IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses.

    IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses.
    Suwanpradid J, Lee MJ, Hoang P, Kwock J, Floyd LP, Smith JS, Yin Z, Atwater AR, Rajagopal S, Kedl RM, Corcoran DL, Zhang JY, MacLeod AS., Free PMC Article

    12/25/2021
    IL-15 Prevents Renal Fibrosis by Inhibiting Collagen Synthesis: A New Pathway in Chronic Kidney Disease?

    IL-15 Prevents Renal Fibrosis by Inhibiting Collagen Synthesis: A New Pathway in Chronic Kidney Disease?
    Devocelle A, Lecru L, Ferlicot S, Bessede T, Candelier JJ, Giron-Michel J, François H., Free PMC Article

    12/25/2021
    IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma.

    IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma.
    Chauvin JM, Ka M, Pagliano O, Menna C, Ding Q, DeBlasio R, Sanders C, Hou J, Li XY, Ferrone S, Davar D, Kirkwood JM, Johnston RJ, Korman AJ, Smyth MJ, Zarour HM., Free PMC Article

    11/27/2021
    Interleukin-15 in autoimmunity.

    Interleukin-15 in autoimmunity.
    Allard-Chamard H, Mishra HK, Nandi M, Mayhue M, Menendez A, Ilangumaran S, Ramanathan S.

    11/27/2021
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