| Deficiency of INPP4A promotes M2 macrophage polarization in eosinophilic chronic rhinosinusitis with nasal polyps. | Deficiency of INPP4A promotes M2 macrophage polarization in eosinophilic chronic rhinosinusitis with nasal polyps.
Xu Y, Tong X, Liu P, Huang J, Chen S, Liu D, Gu T, Xie Y, Guo D, Xu Y. | 03/29/2024 |
| Whole exome sequencing identified a novel nonsense INPP4A mutation in a family with intellectual disability. | Whole exome sequencing identified a novel nonsense INPP4A mutation in a family with intellectual disability.
Banihashemi S, Tahmasebi-Birgani M, Mohammadiasl J, Hajjari M. | 01/2/2021 |
| miR-935 Inhibits Oral Squamous Cell Carcinoma and Targets Inositol Polyphosphate-4-phosphatase Type IA (INPP4A). | miR-935 Inhibits Oral Squamous Cell Carcinoma and Targets Inositol Polyphosphate-4-phosphatase Type IA (INPP4A).
Maruyama N, Umikawa M, Matsumoto H, Maruyama T, Nishihara K, Nakasone T, Matayoshi A, Goto T, Hirano F, Arasaki A, Nakamura H, Matsuzaki G, Takaesu G. | 11/21/2020 |
| Low INPP4A expression is associated with cell proliferation, migration, and invasion in colorectal cancer. | MicroRNA-935 acts as a prognostic marker and promotes cell proliferation, migration, and invasion in colorectal cancer.
Huang Y, Xiao W, Jiang X, Li H. | 03/21/2020 |
| INPP4A is secreted by airway epithelial cells and extracellular INPP4A critically inhibits airway inflammation and remodeling. | Secretory Inositol Polyphosphate 4-Phosphatase Protects against Airway Inflammation and Remodeling.
Khanna K, Chaudhuri R, Aich J, Pattnaik B, Panda L, Prakash YS, Mabalirajan U, Ghosh B, Agrawal A., Free PMC Article | 12/21/2019 |
| INPP4A could possibly serve as a candidate gene for alterations associated with asbestos exposure. | Driver Gene and Novel Mutations in Asbestos-Exposed Lung Adenocarcinoma and Malignant Mesothelioma Detected by Exome Sequencing.
Mäki-Nevala S, Sarhadi VK, Knuuttila A, Scheinin I, Ellonen P, Lagström S, Rönty M, Kettunen E, Husgafvel-Pursiainen K, Wolff H, Knuutila S. | 12/17/2016 |
| Data adds a new etiology to the spectrum of hindbrain malformations in human, and when presented with myoclonic epilepsy may lead to the clinical suspicion of INPP4A defect. | Hindbrain malformation and myoclonic seizures associated with a deleterious mutation in the INPP4A gene.
Sheffer R, Bennett-Back O, Yaacov B, Edvardson S, Gomori M, Werner M, Fahham D, Anteby I, Frumkin A, Meiner V, Elpeleg O. | 08/29/2015 |
| INPP4A represents the first signalling protein with a function in neurons to suppress excitotoxic cell death | The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death.
Sasaki J, Kofuji S, Itoh R, Momiyama T, Takayama K, Murakami H, Chida S, Tsuya Y, Takasuga S, Eguchi S, Asanuma K, Horie Y, Miura K, Davies EM, Mitchell C, Yamazaki M, Hirai H, Takenawa T, Suzuki A, Sasaki T. | 07/5/2010 |
| The +110832A/G (Thr/Ala) variant of INPP4A was significantly associated with asthma in an Indian population. | A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma.
Sharma M, Batra J, Mabalirajan U, Sharma S, Nagarkatti R, Aich J, Sharma SK, Niphadkar PV, Ghosh B, Sharma M, Batra J, Mabalirajan U, Sharma S, Nagarkatti R, Aich J, Sharma SK, Niphadkar PV, Ghosh B. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesAssessing the reproducibility of asthma candidate gene associations, using genome-wide data.
Rogers AJ, Raby BA, Lasky-Su JA, Murphy A, Lazarus R, Klanderman BJ, Sylvia JS, Ziniti JP, Lange C, Celedón JC, Silverman EK, Weiss ST. A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma.
Sharma M, Batra J, Mabalirajan U, Sharma S, Nagarkatti R, Aich J, Sharma SK, Niphadkar PV, Ghosh B, Sharma M, Batra J, Mabalirajan U, Sharma S, Nagarkatti R, Aich J, Sharma SK, Niphadkar PV, Ghosh B. | 03/13/2008 |
| in quiescent cells, the 4-phosphatase colocalized with early and recycling endosomes | The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane.
Ivetac I, Munday AD, Kisseleva MV, Zhang XM, Luff S, Tiganis T, Whisstock JC, Rowe T, Majerus PW, Mitchell CA., Free PMC Article | 01/21/2010 |