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    AQP9 aquaporin 9 [ Homo sapiens (human) ]

    Gene ID: 366, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    AQP3 and AQP9-Contrary Players in Sepsis?

    AQP3 and AQP9-Contrary Players in Sepsis?
    Thon P, Rahmel T, Ziehe D, Palmowski L, Marko B, Nowak H, Wolf A, Witowski A, Orlowski J, Ellger B, Wappler F, Schwier E, Henzler D, Köhler T, Zarbock A, Ehrentraut SF, Putensen C, Frey UH, Anft M, Babel N, Sitek B, Adamzik M, Bergmann L, Unterberg M, Koos B, Rump K, SepsisDataNet.NRW Research Group., Free PMC Article

    01/30/2024
    The Implication of Aquaporin-9 in the Pathogenesis of Preterm Premature Rupture of Membranes.

    The Implication of Aquaporin-9 in the Pathogenesis of Preterm Premature Rupture of Membranes.
    Ölmez F, Oğlak SC, Can E.

    08/27/2022
    Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency.

    Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency.
    Laemmle A, Poms M, Hsu B, Borsuk M, Rüfenacht V, Robinson J, Sadowski MC, Nuoffer JM, Häberle J, Willenbring H., Free PMC Article

    08/20/2022
    AQP9 and ZAP70 as immune-related prognostic biomarkers suppress proliferation, migration and invasion of laryngeal cancer cells.

    AQP9 and ZAP70 as immune-related prognostic biomarkers suppress proliferation, migration and invasion of laryngeal cancer cells.
    Ren L, Li P, Li Z, Chen Q., Free PMC Article

    05/14/2022
    Clinical implication of aquaporin 9 in non-small cell lung cancer patients: its expression and relationship with clinical features and prognosis.

    Clinical implication of aquaporin 9 in non-small cell lung cancer patients: its expression and relationship with clinical features and prognosis.
    Chen P, Li Q, Zhou Y, Lu H, Chen H, Qian M, Chen J.

    04/16/2022
    Increased maternal serum aquaporin-9 expression in pregnancies complicated with early-onset preeclampsia.

    Increased maternal serum aquaporin-9 expression in pregnancies complicated with early-onset preeclampsia.
    Ölmez F, Oğlak SC, Gedik Özköse Z.

    03/12/2022
    [Association study of single nucleotide polymorphisms of AQP7 and AQP9 genes with type 2 diabetes mellitus among ethnic Han Chinese population].

    [Association study of single nucleotide polymorphisms of AQP7 and AQP9 genes with type 2 diabetes mellitus among ethnic Han Chinese population].
    He S, Yang M, Yang Y, Wang F, Wang X, Lu T, Jiao M, Li Y.

    01/29/2022
    Increased maternal serum aquaporin 9 levels in pregnancies complicated with gestational diabetes mellitus.

    Increased maternal serum aquaporin 9 levels in pregnancies complicated with gestational diabetes mellitus.
    Sezer S, Kaya S, Behram M, Dağ İ.

    01/1/2022
    Maternal physical activity significantly alters the placental transcriptome.

    Maternal physical activity significantly alters the placental transcriptome.
    Loiselle J, Fatica T, Tzaneva V, Vuong N, Holcik M, Adamo KB.

    08/14/2021
    Different expression and localization of aquaporin 7 and aquaporin 9 in granulosa cells, oocytes, and embryos of patients with polycystic ovary syndrome and the negatively correlated relationship with insulin regulation.

    Different expression and localization of aquaporin 7 and aquaporin 9 in granulosa cells, oocytes, and embryos of patients with polycystic ovary syndrome and the negatively correlated relationship with insulin regulation.
    Song WY, Wang Y, Hou XM, Tian CC, Wu L, Ma XS, Jin HX, Yao GD, Sun YP.

    08/7/2021
    The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes.

    The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes.
    Amanzougaghene N, Tajeri S, Yalaoui S, Lorthiois A, Soulard V, Gego A, Rametti A, Risco-Castillo V, Moreno A, Tefit M, van Gemert GJ, Sauerwein RW, Vaillant JC, Ravassard P, Pérignon JL, Froissard P, Mazier D, Franetich JF., Free PMC Article

    07/31/2021
    Aquaporin-9, Mediated by IGF2, Suppresses Liver Cancer Stem Cell Properties via Augmenting ROS/beta-Catenin/FOXO3a Signaling.

    Aquaporin-9, Mediated by IGF2, Suppresses Liver Cancer Stem Cell Properties via Augmenting ROS/β-Catenin/FOXO3a Signaling.
    Zheng X, Li C, Yu K, Shi S, Chen H, Qian Y, Mei Z.

    07/3/2021
    Aquaporin-1 and aquaporin-9 gene variations in sudden infant death syndrome.

    Aquaporin-1 and aquaporin-9 gene variations in sudden infant death syndrome.
    Opdal SH, Ferrante L, Rognum TO, Stray-Pedersen A., Free PMC Article

    06/26/2021
    Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma.

    Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma.
    Xu WH, Shi SN, Xu Y, Wang J, Wang HK, Cao DL, Shi GH, Qu YY, Zhang HL, Ye DW., Free PMC Article

    09/26/2020
    The findings suggest that AQP9 may be involved in the pathogenesis of endometriosis and warrant further investigation as a potential therapeutic target for treating endometriosis.

    Potential roles of aquaporin 9 in the pathogenesis of endometriosis.
    Choi YS, Park JH, Yoon JK, Yoon JS, Kim JS, Lee JH, Yun BH, Park JH, Seo SK, Cho S, Lee BS, Taylor HS.

    07/4/2020
    AQP9 mRNA expression in gastric cancer can be a good prognostic marker in stomach neoplasm patients.

    Significance of aquaporins' expression in the prognosis of gastric cancer.
    Thapa S, Chetry M, Huang K, Peng Y, Wang J, Wang J, Zhou Y, Shen Y, Xue Y, Ji K., Free PMC Article

    03/9/2019
    The results of the present study revealed that AQP9 in the intestinal epithelium has an important role in the development of acute liver injury-induced intestinal epithelium damage.

    The possible association between AQP9 in the intestinal epithelium and acute liver injury‑induced intestinal epithelium damage.
    Xiang T, Ge S, Wen J, Xie J, Yang L, Wu X, Cheng N., Free PMC Article

    02/2/2019
    downregulation of AQP9 in cultured chondrocytes decreased the catabolic gene expression in response to IL1beta stimulation through nuclear factorkappaB signaling.

    Downregulation of aquaporin 9 decreases catabolic factor expression through nuclear factor‑κB signaling in chondrocytes.
    Takeuchi K, Hayashi S, Matumoto T, Hashimoto S, Takayama K, Chinzei N, Kihara S, Haneda M, Kirizuki S, Kuroda Y, Tsubosaka M, Nishida K, Kuroda R.

    11/3/2018
    AQP9 together with CLDN2 may have a role regulating tissue-specific physiological properties in tight junctions in UC. An additional functional role for AQP9 in the synthesis and/or the function of mucus can be implied.

    Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis.
    Taman H, Fenton CG, Hensel IV, Anderssen E, Florholmen J, Paulssen RH., Free PMC Article

    09/15/2018
    Data suggest that expression of aquaporin-9 in term placenta is up-regulated by leptin. These studies used placental explants following term birth via cesarean section.

    Leptin upregulates aquaporin 9 expression in human placenta in vitro.
    Vilariño-García T, Pérez-Pérez A, Dietrich V, Guadix P, Dueñas JL, Varone CL, Damiano AE, Sánchez-Margalet V.

    08/18/2018
    These findings showed that eclamptic seizures induced cell death and that upregulation of AQP4 and AQP9 may play an important role in this pathophysiological process.

    Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure.
    Han X, Huang Q, Liu L, Sha X, Hu B, Liu H., Free PMC Article

    08/18/2018
    AQP9 transports two clinically important for anticancer therapy compounds, monomethyselenic acid and selenite.

    Role of AQP9 in transport of monomethyselenic acid and selenite.
    Geng X, McDermott J, Lundgren J, Liu L, Tsai KJ, Shen J, Liu Z., Free PMC Article

    06/30/2018
    The identification of AQP9-induced tumor sensitivity to 5-Fluorouracil highlights the role of AQP9 in regulating chemosensitivity in colorectal cancer.

    AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer.
    Huang D, Feng X, Liu Y, Deng Y, Chen H, Chen D, Fang L, Cai Y, Liu H, Wang L, Wang J, Yang Z., Free PMC Article

    03/31/2018
    AQP9 overexpression decreased the protein levels of phosphatidylinositol-3-kinase (PI3K), leading to reduced phosphorylation of Akt, and subsequently the protein levels of forkhead box protein O1 (FOXO1) were increased.

    Aquaporin 9 inhibits hepatocellular carcinoma through up-regulating FOXO1 expression.
    Li CF, Zhang WG, Liu M, Qiu LW, Chen XF, Lv L, Mei ZC., Free PMC Article

    01/13/2018
    AQP9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.

    Aquaporin 9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.
    Zhang WG, Li CF, Liu M, Chen XF, Shuai K, Kong X, Lv L, Mei ZC.

    07/22/2017
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