| Causal relationships between CD25 on immune cells and hip osteoarthritis. | Causal relationships between CD25 on immune cells and hip osteoarthritis.
Luo H, Zhu Y, Guo B, Ruan Z, Liu Z, Fan Z, Zhao S., Free PMC Article | 09/26/2023 |
| ISG20 stimulates anti-tumor immunity via a double-stranded RNA-induced interferon response in ovarian cancer. | ISG20 stimulates anti-tumor immunity via a double-stranded RNA-induced interferon response in ovarian cancer.
Chen Z, Yin M, Jia H, Chen Q, Zhang H., Free PMC Article | 06/26/2023 |
| Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis. | Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis.
Karasawa T, Sato R, Imaizumi T, Fujita M, Aizawa T, Tsugawa K, Mattinzoli D, Kawaguchi S, Seya K, Terui K, Joh K, Tanaka H., Free PMC Article | 06/23/2023 |
| Characterization of the induction kinetics and antiviral functions of IRF1, ISG15 and ISG20 in cells infected with gammacoronavirus avian infectious bronchitis virus. | Characterization of the induction kinetics and antiviral functions of IRF1, ISG15 and ISG20 in cells infected with gammacoronavirus avian infectious bronchitis virus.
Liu SY, Huang M, Fung TS, Chen RA, Liu DX., Free PMC Article | 05/8/2023 |
| Internal RNA 2'O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect. | Internal RNA 2'O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect.
El Kazzi P, Rabah N, Chamontin C, Poulain L, Ferron F, Debart F, Canard B, Missé D, Coutard B, Nisole S, Decroly E., Free PMC Article | 04/12/2023 |
| The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals. | The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals.
Cheng J, Fu J, Tan Q, Liu Z, Guo K, Zhang L, He J, Zhou B, Liu X, Li D, Fu J., Free PMC Article | 10/15/2022 |
| High expression of ISG20 predicts a poor prognosis in acute myeloid leukemia. | High expression of ISG20 predicts a poor prognosis in acute myeloid leukemia.
Xiong H, Zhang X, Chen X, Liu Y, Duan J, Huang C. | 12/25/2021 |
| Host Interferon-Stimulated Gene 20 Inhibits Pseudorabies Virus Proliferation. | Host Interferon-Stimulated Gene 20 Inhibits Pseudorabies Virus Proliferation.
Chen X, Sun D, Dong S, Zhai H, Kong N, Zheng H, Tong W, Li G, Shan T, Tong G., Free PMC Article | 11/6/2021 |
| Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection. | Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection.
Ding J, Aldo P, Roberts CM, Stabach P, Liu H, You Y, Qiu X, Jeong J, Maxwell A, Lindenbach B, Braddock D, Liao A, Mor G., Free PMC Article | 10/30/2021 |
| Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20. | Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U., Free PMC Article | 08/21/2021 |
| ISG20 and nuclear exosome promote destabilization of nascent transcripts for spliceosomal U snRNAs and U1 variants. | ISG20 and nuclear exosome promote destabilization of nascent transcripts for spliceosomal U snRNAs and U1 variants.
Kawamoto T, Yoshimoto R, Taniguchi I, Kitabatake M, Ohno M. | 07/10/2021 |
| we have identified a novel mechanism involving ISG20 induction by T3 via the IL-8/p-JAK2/p-STAT3 signaling pathway to promote tumor angiogenesis in HCC. | Stimulation of Interferon-Stimulated Gene 20 by Thyroid Hormone Enhances Angiogenesis in Liver Cancer.
Lin SL, Wu SM, Chung IH, Lin YH, Chen CY, Chi HC, Lin TK, Yeh CT, Lin KH., Free PMC Article | 12/1/2018 |
| In conclusion, the authors identified that the influenza A virus-upregulated Long noncoding RNA lnc-ISG20 is a novel interferon-stimulated gene that elicits its inhibitory effect on influenza A virus replication by enhancing ISG20 expression. They demonstrated that lnc-ISG20 functions as a competitive endogenous RNA to bind miR-326 to reduce its inhibition of ISG20 translation. | Lnc-ISG20 Inhibits Influenza A Virus Replication by Enhancing ISG20 Expression.
Chai W, Li J, Shangguan Q, Liu Q, Li X, Qi D, Tong X, Liu W, Ye X., Free PMC Article | 08/18/2018 |
| Interferon-stimulated gene of 20 kDa protein (ISG20) acts as an innate anti-HBV effector that selectively degrades hepatitis B virus (HBV) RNA and blocks replication of infectious HBV particles. | Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo.
Leong CR, Funami K, Oshiumi H, Mengao D, Takaki H, Matsumoto M, Aly HH, Watashi K, Chayama K, Seya T., Free PMC Article | 02/24/2018 |
| Variation at rs12913965 may affect the risk for shoulder dislocation by affecting the activity of either TICRR or ISG20. | A Genetic Marker Associated with Shoulder Dislocation.
Kim S, Kleimeyer JP, Ahmed MA, Avins AL, Fredericson M, Dragoo JL, Ioannidis JPA. | 09/23/2017 |
| We discovered two genome-wide significant SNPs. The first was novel and near ISG20. The second was in TRIOBP, a gene previously associated with prelingual nonsyndromic hearing loss. Motivated by our TRIOBP results, we also looked at exons in known hearing loss genes, and identified two additional SNPs, rs2877561 in ILDR1 and rs9493672 in EYA4 (at a significance threshold adjusted for number of SNPs in those regions). | A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.
Hoffmann TJ, Keats BJ, Yoshikawa N, Schaefer C, Risch N, Lustig LR., Free PMC Article | 05/13/2017 |
| these data provide a detailed explanation for the specific antiviral action of ISG20 and suggest that ISG20 may act as a promising antiviral drug candidate against IAV. | Influenza A Virus-induced expression of ISG20 inhibits viral replication by interacting with nucleoprotein.
Qu H, Li J, Yang L, Sun L, Liu W, He H. | 04/8/2017 |
| The results suggest that hantavirus infection interferes with DAXX-mediated apoptosis, and expression of interferon-activated Sp100 and ISG-20 proteins may indicate intracellular intrinsic antiviral attempts. | Death-domain associated protein-6 (DAXX) mediated apoptosis in hantavirus infection is counter-balanced by activation of interferon-stimulated nuclear transcription factors.
Khaiboullina SF, Morzunov SP, Boichuk SV, Palotás A, St Jeor S, Lombardi VC, Rizvanov AA. | 10/19/2013 |
| ISG20 inhibited infections by hepatitis C virus, bovine viral diarrhea virus and hepatitis A virus. Moreover, ISG20 demonstrated cell-type specific antiviral activity against yellow fever virus, a classical flavivirus. | Antiviral activities of ISG20 in positive-strand RNA virus infections.
Zhou Z, Wang N, Woodson SE, Dong Q, Wang J, Liang Y, Rijnbrand R, Wei L, Nichols JE, Guo JT, Holbrook MR, Lemon SM, Li K., Free PMC Article | 01/22/2011 |
| ISG20 has a role in reducing the synthesis of HBV proteins | Cloning, eukaryotic expression of human ISG20 and preliminary study on the effect of its anti-HBV.
Hao Y, Yang D. | 01/21/2010 |
| ISG20has distinctive residues, Met14 and Arg53, to accommodate hydrogen bonds with the 2'-OH group of the UMP ribose, and these residues may be responsible for the preference of ISG20 for RNA substrates | Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease.
Horio T, Murai M, Inoue T, Hamasaki T, Tanaka T, Ohgi T. | 01/21/2010 |