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    AR androgen receptor [ Homo sapiens (human) ]

    Gene ID: 367, updated on 5-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.

    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.
    Hosseinzadeh L, Kikhtyak Z, Laven-Law G, Pederson SM, Puiu CG, D'Santos CS, Lim E, Carroll JS, Tilley WD, Dwyer AR, Hickey TE., Free PMC Article

    03/11/2024
    Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression.

    Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression.
    Ma T, Jin L, Bai S, Liu Z, Wang S, Shen B, Cho Y, Cao S, Sun MJS, Fazli L, Zhang D, Wedderburn C, Zhang DY, Mugon G, Ungerleider N, Baddoo M, Zhang K, Schiavone LH, Burkhardt BR, Fan J, You Z, Flemington EK, Dong X, Dong Y.,

    03/8/2024
    Modelling the distinct roles of epithelial and stromal androgen receptor in the regulation of prostate epithelial dynamics.

    Modelling the distinct roles of epithelial and stromal androgen receptor in the regulation of prostate epithelial dynamics.
    Woodman IL.

    02/21/2024
    Implication of androgen receptor gene dysfunction in human Mullerian duct anomalies.

    Implication of androgen receptor gene dysfunction in human Müllerian duct anomalies.
    Li L, Chen S, Li S, Duan AH, Lu D, Chu C.

    02/21/2024
    Structural insights into the mechanism of resistance to bicalutamide by the clinical mutations in androgen receptor in chemo-treatment resistant prostate cancer.

    Structural insights into the mechanism of resistance to bicalutamide by the clinical mutations in androgen receptor in chemo-treatment resistant prostate cancer.
    Majeed A, Tahir Ul Qamar M, Maryam A, Mirza MU, Alhussain L, Al Otaibi SO, Almatroudi A, Allemailem KS, Alrumaihi F, Aloliqi AA, Alshehri FF.

    02/16/2024
    A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells.

    A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells.
    Kalyanaraman H, Casteel DE, China SP, Zhuang S, Boss GR, Pilz RB., Free PMC Article

    02/8/2024
    ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.

    ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.
    Mazzeo L, Ghosh S, Di Cicco E, Isma J, Tavernari D, Samarkina A, Ostano P, Youssef MK, Simon C, Dotto GP., Free PMC Article

    02/7/2024
    Two somatic mutations in the androgen receptor N-terminal domain are oncogenic drivers in hepatocellular carcinoma.

    Two somatic mutations in the androgen receptor N-terminal domain are oncogenic drivers in hepatocellular carcinoma.
    Ren QN, Huang DH, Zhang XN, Wang YN, Zhou YF, Zhang MY, Wang SC, Mai SJ, Wu DH, Wang HY., Free PMC Article

    01/26/2024
    CAG and GGN repeat polymorphisms in the androgen receptor gene of a Chilean pediatric cohort with idiopathic inguinal cryptorchidism.

    CAG and GGN repeat polymorphisms in the androgen receptor gene of a Chilean pediatric cohort with idiopathic inguinal cryptorchidism.
    Rodríguez F, Godoy MJ, Ortiz E, Benítez-Filselcker A, López MT, Cassorla F, Castro A.

    01/16/2024
    Small Indels in the Androgen Receptor Gene: Phenotype Implications and Mechanisms of Mutagenesis.

    Small Indels in the Androgen Receptor Gene: Phenotype Implications and Mechanisms of Mutagenesis.
    Ramos RM, Petroli RJ, D'Alessandre NDR, Guardia GA, Afonso ACF, Nishi MY, Domenice S, Galante PAF, Mendonca BB, Batista RL.

    01/11/2024
    Regulation of androgen receptor stability by the beta1 Pix/STUB1 complex.

    Regulation of androgen receptor stability by the β(1) Pix/STUB1 complex.
    Chahdi A, Jorgez C, Seth A.

    01/11/2024
    Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype.

    Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype.
    Asemota S, Effah W, Young KL, Holt J, Cripe L, Ponnusamy S, Thiyagarajan T, Hwang DJ, He Y, Mcnamara K, Johnson D, Wang Y, Grimes B, Khosrosereshki Y, Hollingsworth TJ, Fleming MD, Pritchard FE, Hendrix A, Khan F, Fan M, Makowski L, Yin Z, Sasano H, Hayes DN, Pfeffer LM, Miller DD, Narayanan R., Free PMC Article

    01/5/2024
    Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor.

    Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor.
    Turpin A, Delliaux C, Parent P, Chevalier H, Escudero-Iriarte C, Bonardi F, Vanpouille N, Flourens A, Querol J, Carnot A, Leroy X, Herranz N, Lanel T, Villers A, Olivier J, Touzet H, de Launoit Y, Tian TV, Duterque-Coquillaud M., Free PMC Article

    01/3/2024
    MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer.

    MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer.
    Crowell PD, Giafaglione JM, Jones AE, Nunley NM, Hashimoto T, Delcourt AML, Petcherski A, Agrawal R, Bernard MJ, Diaz JA, Heering KY, Huang RR, Low JY, Matulionis N, Navone NM, Ye H, Zoubeidi A, Christofk HR, Rettig MB, Reiter RE, Haffner MC, Boutros PC, Shirihai OS, Divakaruni AS, Goldstein AS.

    12/5/2023
    Androgen receptor promotes cell stemness via interacting with co-factor YAP1 in gastric cancer.

    Androgen receptor promotes cell stemness via interacting with co-factor YAP1 in gastric cancer.
    Hou J, Pan T, Li F, Sang Q, Wu X, Li J, Yu B, Zang M, Zhu ZG, Su L, Liu B.

    12/5/2023
    Clinical Impact of Androgen Receptor-Suppressing miR-146b Expression in Papillary Thyroid Cancer Aggressiveness.

    Clinical Impact of Androgen Receptor-Suppressing miR-146b Expression in Papillary Thyroid Cancer Aggressiveness.
    Chou CK, Chi SY, Hung YY, Yang YC, Fu HC, Wang JH, Chen CC, Kang HY.

    11/28/2023
    Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions.

    Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions.
    Guo J, Wei Z, Jia T, Wang L, Nama N, Liang J, Liao X, Liu X, Gao Y, Liu X, Wang K, Fu B, Chen SS., Free PMC Article

    11/18/2023
    The Mutational and Transcriptional Landscapes of Speckle-Type POZ Protein (SPOP) and Androgen Receptor (AR) in a Single-Center pT3 Prostatectomy Cohort.

    The Mutational and Transcriptional Landscapes of Speckle-Type POZ Protein (SPOP) and Androgen Receptor (AR) in a Single-Center pT3 Prostatectomy Cohort.
    Eryilmaz IE, Vuruskan BA, Kaygisiz O, Cecener G, Egeli U, Vuruskan H.

    11/18/2023
    Characterization of prostate cancer adrenal metastases: dependence upon androgen receptor signaling and steroid hormones.

    Characterization of prostate cancer adrenal metastases: dependence upon androgen receptor signaling and steroid hormones.
    Sakellakis MJ, Hahn AW, Ramachandran S, Zhang M, Hoang A, Song JH, Liu J, Wang F, Basu HS, Sheperd P, Wang X, Frigo DE, Lin SH, Panaretakis T, Zhang J, Navone N, Troncoso P, Logothetis CJ, Titus MA.

    11/15/2023
    Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney.

    Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney.
    Xiong L, Liu J, Han SY, Koppitch K, Guo JJ, Rommelfanger M, Miao Z, Gao F, Hallgrimsdottir IB, Pachter L, Kim J, MacLean AL, McMahon AP.,

    11/13/2023
    Impact of androgen receptor alterations on cell-free DNA genomic profiling on survival outcomes in metastatic castration-resistant prostate cancer.

    Impact of androgen receptor alterations on cell-free DNA genomic profiling on survival outcomes in metastatic castration-resistant prostate cancer.
    Tripathi N, Thomas VM, Sayegh N, Gebrael G, Chigarira B, Jo Y, Li H, Sahu KK, Nussenzveig R, Nordblad B, Swami U, Agarwal N, Maughan BL.

    11/6/2023
    Cancer Stem Cells and Androgen Receptor Signaling: Partners in Disease Progression.

    Cancer Stem Cells and Androgen Receptor Signaling: Partners in Disease Progression.
    Quintero JC, Díaz NF, Rodríguez-Dorantes M, Camacho-Arroyo I., Free PMC Article

    11/2/2023
    HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.

    HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.
    Morozov VM, Riva A, Sarwar S, Kim WJ, Li J, Zhou L, Licht JD, Daaka Y, Ishov AM., Free PMC Article

    11/1/2023
    Characterization of a novel androgen receptor gene variant identified in an Iranian family with complete androgen insensitivity syndrome (CAIS): a molecular dynamics simulation study.

    Characterization of a novel androgen receptor gene variant identified in an Iranian family with complete androgen insensitivity syndrome (CAIS): a molecular dynamics simulation study.
    Aghaei S, Parvizpour S, Farrokhi E, Molavi N, Hoseinzadeh M, Tabatabaiefar MA.

    11/1/2023
    Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism.

    Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism.
    Yin L, Qi S, Zhu Z., Free PMC Article

    11/1/2023
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