U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ITGA2 integrin subunit alpha 2 [ Homo sapiens (human) ]

    Gene ID: 3673, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    PSAT1 Promotes Metastasis via p-AKT/SP1/ITGA2 Axis in Estrogen Receptor-Negative Breast Cancer Cell.

    PSAT1 Promotes Metastasis via p-AKT/SP1/ITGA2 Axis in Estrogen Receptor-Negative Breast Cancer Cell.
    Zhang X, Wang S, Li W, Wang J, Gong Y, Chen Q, Cao S, Pang D, Gao S., Free PMC Article

    09/11/2024
    ITGA2 as a prognostic factor of glioma promotes GSCs invasion and EMT by activating STAT3 phosphorylation.

    ITGA2 as a prognostic factor of glioma promotes GSCs invasion and EMT by activating STAT3 phosphorylation.
    Zhang J, Li R, Zhang H, Wang S, Zhao Y.

    04/23/2024
    Integrin alpha2 promotes immune escape in non-small-cell lung cancer by enhancing PD-L1 expression in exosomes to inhibit CD8 + T-cell activity.

    Integrin α2 promotes immune escape in non-small-cell lung cancer by enhancing PD-L1 expression in exosomes to inhibit CD8 + T-cell activity.
    Jing H, Meng M, Ye M, Liu S, Cao X, Li K, Liu Y, Zhang J, Wu Y.

    12/20/2023
    High expression ITGA2 affects the expression of MET, PD-L1, CD4 and CD8 with the immune microenvironment in pancreatic cancer patients.

    High expression ITGA2 affects the expression of MET, PD-L1, CD4 and CD8 with the immune microenvironment in pancreatic cancer patients.
    Jin L, Duan Y, Li X, Li Z, Hu J, Shi H, Su Z, Li Z, Du B, Chen Y, Tan Y., Free PMC Article

    11/14/2023
    SDC1 and ITGA2 as novel prognostic biomarkers for PDAC related to IPMN.

    SDC1 and ITGA2 as novel prognostic biomarkers for PDAC related to IPMN.
    Zhang CL, Shen Q, Liu FD, Yang F, Gao MQ, Jiang XC, Li Y, Zhang XY, En GE, Pan X, Pang B., Free PMC Article

    11/3/2023
    BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.

    BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.
    Chen Y, Jin L, Ma Y, Liu Y, Zhu Q, Huang Y, Feng W., Free PMC Article

    09/8/2023
    Hypomethylation-mediated overexpression of ITGA2 stimulates cell invasion and migration of thyroid carcinoma.

    Hypomethylation-mediated overexpression of ITGA2 stimulates cell invasion and migration of thyroid carcinoma.
    Chen H, Zhang C, Li Y, Chen C.

    06/28/2023
    Macrophages Promote Ovarian Cancer-Mesothelial Cell Adhesion by Upregulation of ITGA2 and VEGFC in Mesothelial Cells.

    Macrophages Promote Ovarian Cancer-Mesothelial Cell Adhesion by Upregulation of ITGA2 and VEGFC in Mesothelial Cells.
    Cho SK, Lee K, Woo JH, Choi JH., Free PMC Article

    02/15/2023
    Integrin alpha 2 is associated with tumor progression and postoperative recurrence in non-small cell lung cancer.

    Integrin alpha 2 is associated with tumor progression and postoperative recurrence in non-small cell lung cancer.
    Matsumoto Y, Kage H, Morota M, Zokumasu K, Ando T, Maemura K, Watanabe K, Kawakami M, Hinata M, Ushiku T, Nakajima J, Nagase T.

    01/28/2023
    The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation.

    The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation.
    Hunter EJ, Hamaia SW, Kim PS, Malcor JM, Farndale RW., Free PMC Article

    01/11/2023
    Elevated ITGA2 expression promotes collagen type I-induced clonogenic growth of intrahepatic cholangiocarcinoma.

    Elevated ITGA2 expression promotes collagen type I-induced clonogenic growth of intrahepatic cholangiocarcinoma.
    Rattanasinchai C, Navasumrit P, Ruchirawat M., Free PMC Article

    12/31/2022
    ITGA2 induces STING expression in pancreatic cancer by inducing DNMT1 degradation.

    ITGA2 induces STING expression in pancreatic cancer by inducing DNMT1 degradation.
    Meng J, Cai H, Sun Y, Wen S, Wu H, Ren D.

    12/24/2022
    ITGA2 Gene Polymorphism Is Associated with Type 2 Diabetes Mellitus in the Kazakhstan Population.

    ITGA2 Gene Polymorphism Is Associated with Type 2 Diabetes Mellitus in the Kazakhstan Population.
    Magazova A, Ashirbekov Y, Abaildayev A, Satken K, Balmukhanova A, Akanov Z, Jainakbayev N, Balmukhanova A, Sharipov K., Free PMC Article

    11/5/2022
    Anti-human platelet antigen-5b antibodies and fetal and neonatal alloimmune thrombocytopenia; incidental association or cause and effect?

    Anti-human platelet antigen-5b antibodies and fetal and neonatal alloimmune thrombocytopenia; incidental association or cause and effect?
    Alm J, Duong Y, Wienzek-Lischka S, Cooper N, Santoso S, Sachs UJ, Kiefel V, Bein G.

    07/2/2022
    MicroRNA-99a-3p/GRP94 axis affects metastatic progression of human papillary thyroid carcinoma by regulating ITGA2 expression and localization.

    MicroRNA-99a-3p/GRP94 axis affects metastatic progression of human papillary thyroid carcinoma by regulating ITGA2 expression and localization.
    Gao Y, Pan Y, Wang T, Yao Y, Yuan W, Zhu X, Wang K.

    03/19/2022
    Expression and prognostic impact of CD49b in human lung cancer.

    Expression and prognostic impact of CD49b in human lung cancer.
    Tirilomi A, Elakad O, Yao S, Li Y, Hinterthaner M, Danner BC, Ströbel P, Tirilomis T, Bohnenberger H, von Hammerstein-Equord A., Free PMC Article

    02/26/2022
    A novel long non-coding RNA regulates the integrin, ITGA2 in breast cancer.

    A novel long non-coding RNA regulates the integrin, ITGA2 in breast cancer.
    Verhoeff TJ, Holloway AF, Dickinson JL.

    02/19/2022
    MicroRNA miR-145-5p regulates cell proliferation and cell migration in colon cancer by inhibiting chemokine (C-X-C motif) ligand 1 and integrin alpha2.

    MicroRNA miR-145-5p regulates cell proliferation and cell migration in colon cancer by inhibiting chemokine (C-X-C motif) ligand 1 and integrin α2.
    Zhuang W, Niu T, Li Z., Free PMC Article

    02/19/2022
    The Stiffness of Cardiac Fibroblast Substrates Exerts a Regulatory Influence on Collagen Metabolism via alpha2beta1 Integrin, FAK and Src Kinases.

    The Stiffness of Cardiac Fibroblast Substrates Exerts a Regulatory Influence on Collagen Metabolism via α2β1 Integrin, FAK and Src Kinases.
    Gałdyszyńska M, Radwańska P, Szymański J, Drobnik J., Free PMC Article

    01/8/2022
    ITGA2 protein is associated with rheumatoid arthritis in Chinese and affects cellular function of T cells.

    ITGA2 protein is associated with rheumatoid arthritis in Chinese and affects cellular function of T cells.
    He P, Wang BH, Cao RR, Zhu DC, Ge B, Zhou X, Wu LF, Lei SF, Deng FY.

    12/11/2021
    Integrin alpha2 gene polymorphism is a risk factor of coronary artery lesions in Chinese children with Kawasaki disease.

    Integrin α2 gene polymorphism is a risk factor of coronary artery lesions in Chinese children with Kawasaki disease.
    Yuan J, Jiang Z, Li M, Li W, Gu X, Wang Z, Pi L, Xu Y, Zhou H, Zhang B, Deng Q, Wang Y, Huang P, Zhang L, Gu X., Free PMC Article

    11/6/2021
    Integrin alpha2beta1 as a negative regulator of the laminin receptors alpha6beta1 and alpha6beta4.

    Integrin α(2)β(1) as a negative regulator of the laminin receptors α(6)β(1) and α(6)β(4).
    Dao L, Blaue C, Franz CM.

    11/6/2021
    Exosomes with low miR-34c-3p expression promote invasion and migration of non-small cell lung cancer by upregulating integrin alpha2beta1.

    Exosomes with low miR-34c-3p expression promote invasion and migration of non-small cell lung cancer by upregulating integrin α2β1.
    Huang W, Yan Y, Liu Y, Lin M, Ma J, Zhang W, Dai J, Li J, Guo Q, Chen H, Makabel B, Liu H, Su C, Bi H, Zhang J., Free PMC Article

    10/16/2021
    Association of BglII Polymorphism in ITGA2 and (894G/T and -786T/C) Polymorphisms in eNOS Gene With Stroke Susceptibility in Tunisian Patients alpha2 Gene Polymorphism in alpha2beta1 Integrin and eNOS Gene Variants and Stroke.

    Association of BglII Polymorphism in ITGA2 and (894G/T and -786T/C) Polymorphisms in eNOS Gene With Stroke Susceptibility in Tunisian Patients α2 Gene Polymorphism in α2β1 Integrin and eNOS Gene Variants and Stroke.
    Jalel A, Midani F, Fredj SH, Messaoud T, Hentati F, Soualmia H.

    10/2/2021
    Interactions via alpha2beta1 Cell Integrin May Protect against the Progression of Airway Structural Changes in Asthma.

    Interactions via α(2)β(1) Cell Integrin May Protect against the Progression of Airway Structural Changes in Asthma.
    Bazan-Socha S, Jakiela B, Zuk J, Zarychta J, Soja J, Okon K, Dziedzina S, Zareba L, Dropinski J, Wojcik K, Padjas A, Marcinkiewicz C, Bazan JG., Free PMC Article

    07/17/2021
    firstprevious page of 11 nextlast