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    ITGB1 integrin subunit beta 1 [ Homo sapiens (human) ]

    Gene ID: 3688, updated on 20-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin beta1 in Kawasaki disease.

    Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease.
    Huang J, Zhao C, Zhang S., Free PMC Article

    05/16/2024
    IGSF10 inhibits the metastasis of lung adenocarcinoma via the Spi-B/Integrin-beta1 signaling pathway.

    IGSF10 inhibits the metastasis of lung adenocarcinoma via the Spi-B/Integrin-β1 signaling pathway.
    Ling B, Ye G, Qin C, Liao X, Yang R, Su L, Qi G.

    04/22/2024
    N-linked alpha2,6-sialylation of integrin beta1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.

    N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.
    Liu J, Dong X, Xie R, Tang Y, Thomas AM, Li S, Liu S, Yu M, Qin H.

    04/12/2024
    Osteosarcoma Cells Secrete CXCL14 That Activates Integrin alpha11beta1 on Fibroblasts to Form a Lung Metastatic Niche.

    Osteosarcoma Cells Secrete CXCL14 That Activates Integrin α11β1 on Fibroblasts to Form a Lung Metastatic Niche.
    Xu Y, Deng C, Chen H, Song Y, Xu H, Song G, Wang X, Luo T, Chen W, Ma J, Zeng A, Huang S, Chen Z, Fu J, Gong M, Tai Y, Huang A, Feng H, Hu J, Zhu X, Tang Q, Lu J, Wang J.

    04/8/2024
    A decrease in integrin alpha5beta1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection.

    A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection.
    Xue M, Xing L, Yang Y, Shao M, Liao F, Xu F, Chen Y, Wang S, Chen B, Yao C, Gu G, Tong C., Free PMC Article

    03/29/2024
    CD93 regulates breast cancer growth and vasculogenic mimicry through the PI3K/AKT/SP2 signaling pathway activated by integrin beta1.

    CD93 regulates breast cancer growth and vasculogenic mimicry through the PI3K/AKT/SP2 signaling pathway activated by integrin β1.
    Liu H, Zhang J, Zhao Y, Fan Z, Yang Y, Mao Y, Yang J, Ma S.

    03/25/2024
    Suppression of the METTL3-m[6]A-integrin beta1 axis by extracellular acidification impairs T cell infiltration and antitumor activity.

    Suppression of the METTL3-m(6)A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity.
    Wang Z, Shang J, Qiu Y, Cheng H, Tao M, Xie E, Pei X, Li W, Zhang L, Wu A, Li G.

    03/5/2024
    Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1.

    Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1.
    Lv T, Liu H, Mao L, Song Y, Liao L, Zhong K, Shuai B, Luo Y, Guo T, Huang W, Zhang S., Free PMC Article

    02/12/2024
    microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin beta1 recycling on the membrane.

    microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin β1 recycling on the membrane.
    Bhattacharya S, Sarker S, Das S, Ahir M, Chattopadhyay S, Ghosh S, Adhikary A.

    02/8/2024
    DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-alpha5beta1/FAK/AKT signaling.

    DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
    Liu C, Xu J, Fan J, Liu C, Xie W, Kong H.

    02/4/2024
    Integrinbeta-1 in disorders and cancers: molecular mechanisms and therapeutic targets.

    Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targets.
    Su C, Mo J, Dong S, Liao Z, Zhang B, Zhu P., Free PMC Article

    01/30/2024
    The characteristics and the multiple functions of integrin beta1 in human cancers.

    The characteristics and the multiple functions of integrin β1 in human cancers.
    Sun L, Guo S, Xie Y, Yao Y., Free PMC Article

    11/28/2023
    Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.

    Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.
    Xia W, Chen X, Zhu Z, Chen H, Li B, Wang K, Huang L, Liu Z, Chen Z., Free PMC Article

    11/1/2023
    Role of beta1-integrin in promoting cell motility and tamoxifen resistance of human breast cancer MCF-7 cells.

    Role of β1-integrin in promoting cell motility and tamoxifen resistance of human breast cancer MCF-7 cells.
    Hu S, Yang Q, Chen Z, Fu W.

    09/26/2023
    ZCCHC4 Promotes Osteosarcoma Progression by Upregulating ITGB1.

    ZCCHC4 Promotes Osteosarcoma Progression by Upregulating ITGB1.
    Luo L, Tang X, Liu L, Tang G, Chen L, Chang G, Xiao Z.

    08/25/2023
    N-glycosylation by N-acetylglucosaminyltransferase IVa enhances the interaction of integrin beta1 with vimentin and promotes hepatocellular carcinoma cell motility.

    N-glycosylation by N-acetylglucosaminyltransferase IVa enhances the interaction of integrin β1 with vimentin and promotes hepatocellular carcinoma cell motility.
    Yang D, Han F, Cai J, Sun H, Wang F, Jiang M, Zhang M, Yuan M, Zhou W, Li H, Yang L, Bai Y, Xiao L, Dong H, Cheng Q, Mao H, Zhou L, Wang R, Li Y, Nie H.

    08/20/2023
    TMTC1 promotes invasiveness of ovarian cancer cells through integrins beta1 and beta4.

    TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4.
    Yeh TC, Lin NY, Chiu CY, Hsu TW, Wu HY, Lin HY, Chen CH, Huang MC., Free PMC Article

    08/17/2023
    The WAVE2/miR-29/Integrin-beta1 Oncogenic Signaling Axis Promotes Tumor Growth and Metastasis in Triple-negative Breast Cancer.

    The WAVE2/miR-29/Integrin-β1 Oncogenic Signaling Axis Promotes Tumor Growth and Metastasis in Triple-negative Breast Cancer.
    Rana PS, Wang W, Markovic V, Szpendyk J, Chan ER, Sossey-Alaoui K., Free PMC Article

    08/10/2023
    Integrin beta1 is a key determinant of the expression of angiotensin-converting enzyme 2 (ACE2) in the kidney epithelial cells.

    Integrin β1 is a key determinant of the expression of angiotensin-converting enzyme 2 (ACE2) in the kidney epithelial cells.
    Mia MS, Hossain D, Woodbury E, Kelleher S, Palamuttam RJ, Rao R, Steen P, Jarajapu YP, Mathew S., Free PMC Article

    06/28/2023
    A novel computational predictive biological approach distinguishes Integrin beta1 as a salient biomarker for breast cancer chemoresistance.

    A novel computational predictive biological approach distinguishes Integrin β1 as a salient biomarker for breast cancer chemoresistance.
    Das S, Kundu M, Hassan A, Parekh A, Jena BC, Mundre S, Banerjee I, Yetirajam R, Das CK, Pradhan AK, Das SK, Emdad L, Mitra P, Fisher PB, Mandal M.

    06/7/2023
    FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin beta1 Degradation.

    FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation.
    Mieczkowski K, Popeda M, Lesniak D, Sadej R, Kitowska K., Free PMC Article

    05/19/2023
    ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma.

    ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma.
    Shi Y, Shang J, Li Y, Zhong D, Zhang Z, Yang Q, Lai C, Feng T, Yao Y, Huang X., Free PMC Article

    02/24/2023
    ALKBH5 activates FAK signaling through m6A demethylation in ITGB1 mRNA and enhances tumor-associated lymphangiogenesis and lymph node metastasis in ovarian cancer.

    ALKBH5 activates FAK signaling through m6A demethylation in ITGB1 mRNA and enhances tumor-associated lymphangiogenesis and lymph node metastasis in ovarian cancer.
    Sun R, Yuan L, Jiang Y, Wan Y, Ma X, Yang J, Sun G, Zhou S, Wang H, Qiu J, Zhang L, Cheng W., Free PMC Article

    02/15/2023
    Integrin beta1 and the Repair after Nervous System Injury.

    Integrin β1 and the Repair after Nervous System Injury.
    Yan L, Cui Z.

    02/11/2023
    Dysregulation of integrin alphavbeta3 and alpha5beta1 impedes migration of placental endothelial cells in fetal growth restriction.

    Dysregulation of integrin αvβ3 and α5β1 impedes migration of placental endothelial cells in fetal growth restriction.
    Gumina DL, Ji S, Flockton A, McPeak K, Stich D, Moldovan R, Su EJ., Free PMC Article

    10/15/2022
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