| The association of five polymorphisms with diabetic retinopathy in a Chinese population. | The association of five polymorphisms with diabetic retinopathy in a Chinese population.
Li H, Ning M, Li Q, Wang T, Li W, Xiao J, Wang L, Wang K, Zou R, Hao F, Yu M, Shi Y, Lei C, Wang Z, Yang Z, Xu H, Gong B. | 07/12/2023 |
| A SUMO4 initiator codon variant in amyotrophic lateral sclerosis reduces SUMO4 expression and alters stress granule dynamics. | A SUMO4 initiator codon variant in amyotrophic lateral sclerosis reduces SUMO4 expression and alters stress granule dynamics.
Osmanovic A, Förster A, Widjaja M, Auber B, Das AM, Christians A, Brand F, Petri S, Weber RG., Free PMC Article | 08/27/2022 |
| Small ubiquitin-related modifier (SUMO) 3 and SUMO4 gene polymorphisms in Parkinson's disease. | Small ubiquitin-related modifier (SUMO) 3 and SUMO4 gene polymorphisms in Parkinson's disease.
Küçükali CI, Salman B, Yüceer H, Ulusoy C, Abacı N, Ekmekci SS, Tüzün E, Bilgiç B, Hanağası HA. | 03/20/2021 |
| Donor SUMO4 rs237025 genetic variant was associated with higher tacrolimus C/D ratios in the early period after liver transplantation, which might be related to the down-regulation of CYP3A5 enzyme through the NF-kB signalling pathway. | Association of donor small ubiquitin-like modifier 4 rs237025 genetic variant with tacrolimus elimination in the early period after liver transplantation.
Zhang T, Liu Y, Zeng R, Ling Q, Wen P, Fan J, Peng Z. | 01/12/2019 |
| meta-analysis demonstrated that the G allele of the SUMO4 M55V polymorphism could be a susceptible risk locus to type 2 diabetes mellitus, mainly in the Chinese population, while the association in other ethnic population needs to be further validated | Association between the SUMO4 M55V Polymorphism and Susceptibility to Type 2 Diabetes Mellitus: A Meta-analysis.
Zhang Q, Liu D, Zhao ZY, Sun Q, Ding LX, Wang YX. | 10/14/2017 |
| Both donor and recipient SUMO4 rs237025 polymorphisms contribute to the development of new-onset diabetes mellitus after liver transplantation. | Association of donor and recipient SUMO4 rs237025 genetic variant with new-onset diabetes mellitus after liver transplantation in a Chinese population.
Zhang T, Liu Y, Hu Y, Zhang X, Zhong L, Fan J, Peng Z. | 09/23/2017 |
| Results show that SUMO-4 is expressed in normal placental development. SUMO-4 expression was increased in pre-eclamptic placentas and in models of oxidative stress and hypoxic injury suggesting that SUMO-4 hyper-SUMOylation may be a potential post-translational mechanism in the stressed pre-eclamptic placenta. | SUMO-4: A novel functional candidate in the human placental protein SUMOylation machinery.
Baczyk D, Audette MC, Drewlo S, Levytska K, Kingdom JC., Free PMC Article | 09/23/2017 |
| study suggests that SUMO4 c.163 G to A polymorphism is associated with the susceptibility to diabetic nephropathy in north Indian subjects with type 2 diabetes | SUMO4 163 G>A variation is associated with kidney disease in Indian subjects with type 2 diabetes.
Sinha N, Yadav AK, Kumar V, Dutta P, Bhansali A, Jha V. | 12/31/2016 |
| SUMO4 M55V polymorphism and type-2 diabetes were significantly associated with a possible SUMO4 region to type-2 diabetes susceptibility. | Association of SUMO4 M55V and -94ins/del gene variants with type-2 diabetes.
Sozen S, Horozoglu C, Bireller ES, Karaali Z, Cakmakoglu B. | 05/23/2015 |
| No association between SUMO4 gene polymorphisms and acoronary artery disease with and without type 2 diabetes mellitus. | [Association between SUMO4 polymorphisms and coronary artery disease with and without type 2 diabetes mellitus].
Pu LM, Nan N, Yang Z, Jin ZN. | 06/15/2013 |
| SUMO4 Met55Val variant was associated with increased insulin resistance in Chinese patients with newly diagnosed type 2 diabetes. | Association of SUMO4 Met55Val variation with increased insulin resistance in newly diagnosed type 2 diabetes in a Chinese population.
Ji Z, Dai Z, Huang Y, Martins HA, Xu Y. | 05/4/2013 |
| study demonstrates significant associations of SUMO4 M55V polymorphism with type 1 diabetes mellitus in Asian and Caucasian population and with type 2 diabetes mellitus in Asian population | Polymorphism M55V in gene encoding small ubiquitin-like modifier 4 (SUMO4) protein associates with susceptibility to type 1 (and type 2) diabetes.
Tang ST, Peng WJ, Wang CJ, Tang HQ, Zhang Q. | 05/4/2013 |
| The C438T polymorphism in the SUMO4 gene is associated with significantly increased risk of papulopustular skin lesions in HLA-B51-positive Behcet's disease patients. | SUMO4 C438T polymorphism is associated with papulopustular skin lesion in Korean patients with Behçet's disease.
Park G, Kim HS, Choe JY, Kim SK. | 02/23/2013 |
| This meta-analysis indicates that the SUMO4 M55V polymorphism confers susceptibility to type I diabetes in Asians and Europeans. | Association between the SUMO4 M55V (A163G) polymorphism and susceptibility to type 1 diabetes: a meta-analysis.
Song GG, Choi SJ, Ji JD, Lee YH. | 02/9/2013 |
| the association between small ubiquitin-like modifier 4 (SUMO4) gene polymorphisms and type 2 diabetes mellitus | [Association between SUMO4 polymorphisms and type 2 diabetes mellitus].
Pu LM, Nan N, Yang Z, Jin ZN. | 05/12/2012 |
| Letter: report SUMO4 polymorphisms associated with protective effect in Tunisian rheumatoid arthritis patients. | Association of small ubiquitin-like modifier 4 gene polymorphisms with rheumatoid arthritis in a Tunisian population.
Fakhfakh Karray E, Bendhifallah I, Zakraoui L, Hamzaoui K. | 11/5/2011 |
| The SUMO4 gene single nucleotide polymorphism variant is not associated with susceptibility of the type 2 diabetes polymorphism. | No association of the SUMO4 polymorphism M55V variant in type 2 diabetes in Iranian subjects.
Fallah S, Jafarzadeh M, Hedayati M. | 02/5/2011 |
| SUMO4 gene polymorphisms may be involved in the development of skin lesions, vascular Behcet's disease, as well as the severity of the disease. | Association of small ubiquitin-like modifier 4 (SUMO4) polymorphisms in a Tunisian population with Behçet's disease.
Kamoun M, Ben Dhifallah I, Karray E, Zakraoui L, Hamzaoui K. | 01/22/2011 |
| SUMO4 gene M55V variant is associated with the genetic susceptibility of type 1 diabetes mellitus (T1D) in Chinese children. | Association of SUMO4 M55V polymorphism with type 1 diabetes in Chinese children.
Sang Y, Zong W, Liu M, Yan J. | 01/15/2011 |
| This study suggests that in Taiwan the SUMO4 Met 55Val polymorphism is associated with susceptibility to T2DM and Type 2 diabetic patients with GG genotype have worse glycemic control. | Small ubiquitin-like modifier-4 Met55Val polymorphism is associated with glycemic control of Type 2 diabetes mellitus in Taiwan.
Lin HY, Li SL, Yu ML, Hsiao PJ, Hsieh MC, Lin KD, Wang CL, Wang TN, Shin SJ. | 10/23/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.
Potter C, Cordell HJ, Barton A, Daly AK, Hyrich KL, Mann DA, Morgan AW, Wilson AG, Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Isaacs JD. | 06/30/2010 |
| total of 2317 families were genotyped for 15 SNPs in the SUMO4 region. | Analyses of multiple single-nucleotide polymorphisms in the SUMO4/IDDM5 region in affected sib-pair families with type I diabetes.
Podolsky R, Prasad Linga-Reddy MV, She JX, Type I Diabetes Genetics Consortium., Free PMC Article | 02/8/2010 |
| Association of the polymorphism of SUMO4 with risk of coronary heart disease in type 2 diabetes is suggested. | SUMO4 Met55Val polymorphism is associated with coronary heart disease in Japanese type 2 diabetes individuals.
Shimada T, Furukawa Y, Furuta H, Yasuda K, Matsuno S, Kusuyama A, Doi A, Nishi M, Sasaki H, Sanke T, Nanjo K. | 01/21/2010 |
| SUMO4 may act as a negative feedback regulator to prevent excessive activation of NFkappaB. | Characterization of a negative feedback network between SUMO4 expression and NFkappaB transcriptional activity.
Wang CY, Yang P, Li M, Gong F. | 01/21/2010 |
| This study examines whether small ubiquitin-like modifier 4 (SUMO4) polymorphisms were associated with Vogt-Koyanagi-Harada (VKH) syndrome in the Chinese Han population. | Small ubiquitin-like modifier 4 (SUMO4) polymorphisms and Vogt-Koyanagi-Harada (VKH) syndrome in the Chinese Han population.
Hou S, Yang P, Du L, Zhou H, Lin X, Liu X, Kijlstra A., Free PMC Article | 01/21/2010 |