| Circulating C1q/TNF-related protein-12 levels are associated with the severity of coronary artery disease. | Circulating C1q/TNF-related protein-12 levels are associated with the severity of coronary artery disease.
Nadimi Shahraki Z, Azimi H, Ilchi N, Rohani Borj M, Pourghadamyari H, Mosallanejad S, Abbaszadeh-Goudarzi K, Sahebkar A. | 02/5/2022 |
| Potential emerging roles of the novel adipokines adipolin/CTRP12 and meteorin-like/METRNL in obesity-osteoarthritis interplay. | Potential emerging roles of the novel adipokines adipolin/CTRP12 and meteorin-like/METRNL in obesity-osteoarthritis interplay.
Sobieh BH, Kassem DH, Zakaria ZM, El-Mesallamy HO. | 01/22/2022 |
| CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRalpha pathway. | CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway.
Wang G, Chen JJ, Deng WY, Ren K, Yin SH, Yu XH., Free PMC Article | 09/18/2021 |
| The results suggest a possible link between CTRP12 and pathogenic mechanisms of atherosclerosis, such as inflammation and high density lipoprotein-cholesterol metabolism. | Decreased serum levels of CTRP12/adipolin in patients with coronary artery disease in relation to inflammatory cytokines and insulin resistance.
Fadaei R, Moradi N, Kazemi T, Chamani E, Azdaki N, Moezibady SA, Shahmohamadnejad S, Fallah S. | 02/22/2020 |
| High Serum adipolin levels are associated with metabolic syndrome and prediabetes. | Proportional correlates of adipolin and cathepsin S in metabolic syndrome patients with and without prediabetes.
Kasabri V, Al-Ghareeb MI, Saleh MI, Suyagh M, Halaseh L, Al-Sarraf I, AlAlawi S. | 01/25/2020 |
| High CTRP12 expression is associated with obesity. | The gene expression of CTRP12 but not CTRP13 is upregulated in both visceral and subcutaneous adipose tissue of obese subjects.
Omidifar A, Toolabi K, Rahimipour A, Emamgholipour S, Shanaki M. | 01/11/2020 |
| Study results indicated that decreased adiponectin, CTRP12, and CTRP13 levels, regardless of obesity, could independently predict polycystic ovarian syndrome (PCOS). This finding suggested a novel link between adipokines and PCOS. | Lower circulating levels of CTRP12 and CTRP13 in polycystic ovarian syndrome: Irrespective of obesity.
Shanaki M, Moradi N, Fadaei R, Zandieh Z, Shabani P, Vatannejad A., Free PMC Article | 06/8/2019 |
| Adipolin and adiponectin are cytokines that exert substantial impact on obesity, progression of atherosclerosis, insulin resistance, and glucose metabolism. | The role of adiponectin and adipolin as anti-inflammatory adipokines in the formation of macrophage foam cells and their association with cardiovascular diseases.
Sargolzaei J, Chamani E, Kazemi T, Fallah S, Soori H. | 07/14/2018 |
| Low serum CTRP12 level is associated with Type 2 diabetes mellitus. | Circulating C1q complement/TNF-related protein (CTRP) 1, CTRP9, CTRP12 and CTRP13 concentrations in Type 2 diabetes mellitus: In vivo regulation by glucose.
Bai B, Ban B, Liu Z, Zhang MM, Tan BK, Chen J., Free PMC Article | 09/2/2017 |
| Coenzyme Q10 reduced HbA1c considerably in overweight and obese patients with diabetes, although interestingly adipolin levels declined simultaneously. In this study, Q10 modulated glucose homeostasis, which was expected to be mediated by increasing adipolin. The similar mechanisms of action of Q10 and adipolin may justify lowering effect of Q10 on adipolin. | The Effect of Coenzyme Q10 Supplementation on Circulating Levels of Novel Adipokine Adipolin/CTRP12 in Overweight and Obese Patients with Type 2 Diabetes.
Mehrdadi P, Kolahdouz Mohammadi R, Alipoor E, Eshraghian MR, Esteghamati A, Hosseinzadeh-Attar MJ. | 03/18/2017 |
| Serum adipolin concentrations were significantly lower in polycystic ovarian syndrome compared with control subjects. | Circulatory changes of the novel adipokine adipolin/CTRP12 in response to metformin treatment and an oral glucose challenge in humans.
Tan BK, Chen J, Hu J, Amar O, Mattu HS, Ramanjaneya M, Patel V, Lehnert H, Randeva HS. | 07/25/2015 |
| In subcutaneous adipose tissue explants, insulin significantly increased CTRP12 protein expression and secretion. | Insulin regulates the novel adipokine adipolin/CTRP12: in vivo and ex vivo effects.
Tan BK, Lewandowski KC, O'Hare JP, Randeva HS. | 05/17/2014 |
| we describe, for the first time, adipolin expression in human chondrocytes as well as the intracellular mechanism involved in its regulation | Expression and modulation of adipolin/C1qdc2: a novel adipokine in human and murine ATDC-5 chondrocyte cell line.
Conde J, Scotece M, López V, Gómez R, Lago F, Pino J, Gómez-Reino JJ, Gualillo O. | 03/9/2013 |
| Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity. | Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity.
Wei Z, Lei X, Seldin MM, Wong GW., Free PMC Article | 12/29/2012 |
| Reports cloning, expression, regulation and function of mouse adipolin (Fam132a) | Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism.
Enomoto T, Ohashi K, Shibata R, Higuchi A, Maruyama S, Izumiya Y, Walsh K, Murohara T, Ouchi N., Free PMC Article | 10/3/2011 |