| Exploring the potential of VGLL3 methylation as a prognostic indicator for intracranial aneurysm with gender-specific considerations. | Exploring the potential of VGLL3 methylation as a prognostic indicator for intracranial aneurysm with gender-specific considerations.
Liu Y, Chen S, Zhang E, Xu Y, Deng X, Hu Z, Nie S, Lin Y, Huang Y., Free PMC Article | 03/5/2024 |
| VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid-liquid phase separation. | VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid-liquid phase separation.
Horii Y, Matsuda S, Toyota C, Morinaga T, Nakaya T, Tsuchiya S, Ohmuraya M, Hironaka T, Yoshiki R, Kasai K, Yamauchi Y, Takizawa N, Nagasaka A, Tanaka A, Kosako H, Nakaya M., Free PMC Article | 02/13/2023 |
| Recurrent VGLL3 fusions define a distinctive subset of spindle cell rhabdomyosarcoma with an indolent clinical course and striking predilection for the head and neck. | Recurrent VGLL3 fusions define a distinctive subset of spindle cell rhabdomyosarcoma with an indolent clinical course and striking predilection for the head and neck.
Agaimy A, Dermawan JK, Leong I, Stoehr R, Swanson D, Weinreb I, Zhang L, Antonescu CR, Dickson BC., Free PMC Article | 10/15/2022 |
| Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway. | Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway.
Du Y, Cui R, Tian N, Chen M, Zhang XL, Dai SM., Free PMC Article | 08/20/2022 |
| VGLL3 increases the dependency of cancer cells on de novo nucleotide synthesis through GART expression. | VGLL3 increases the dependency of cancer cells on de novo nucleotide synthesis through GART expression.
Kawamura T, Takehora Y, Hori N, Takakura Y, Yamaguchi N, Takano H, Yamaguchi N. | 06/18/2022 |
| Clinicopathologic and Molecular Study of Hybrid Nerve Sheath Tumors Reveals Their Common Association With Fusions Involving VGLL3. | Clinicopathologic and Molecular Study of Hybrid Nerve Sheath Tumors Reveals Their Common Association With Fusions Involving VGLL3.
Nihous H, Baud J, Azmani R, Michot A, Perret R, Mayeur L, de Pinieux G, Milin S, Angot E, Duquenne S, Geneste D, Lucchesi C, Le Loarer F, Bouvier C. | 04/23/2022 |
| Hybrid schwannoma-perineurioma frequently harbors VGLL3 rearrangement. | Hybrid schwannoma-perineurioma frequently harbors VGLL3 rearrangement.
Dickson BC, Antonescu CR, Demicco EG, Leong DI, Anderson ND, Swanson D, Zhang L, Fletcher CDM, Hornick JL., Free PMC Article | 01/29/2022 |
| VGLL3 activates inflammatory responses by inducing interleukin-1alpha secretion. | VGLL3 activates inflammatory responses by inducing interleukin-1α secretion.
Takakura Y, Hori N, Terada N, Machida M, Yamaguchi N, Takano H, Yamaguchi N. | 11/13/2021 |
| Immunometabolic function of the transcription cofactor VGLL3 provides an evolutionary rationale for sexual dimorphism in autoimmunity. | Immunometabolic function of the transcription cofactor VGLL3 provides an evolutionary rationale for sexual dimorphism in autoimmunity.
Pagenkopf A, Liang Y., Free PMC Article | 05/15/2021 |
| A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors. | A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors.
Mesrouze Y, Aguilar G, Bokhovchuk F, Martin T, Delaunay C, Villard F, Meyerhofer M, Zimmermann C, Fontana P, Wille R, Vorherr T, Erdmann D, Furet P, Scheufler C, Schmelzle T, Affolter M, Chène P., Free PMC Article | 03/13/2021 |
| Vestigial-like family member 3 (VGLL3), a cofactor for TEAD transcription factors, promotes cancer cell proliferation by activating the Hippo pathway. | Vestigial-like family member 3 (VGLL3), a cofactor for TEAD transcription factors, promotes cancer cell proliferation by activating the Hippo pathway.
Hori N, Okada K, Takakura Y, Takano H, Yamaguchi N, Yamaguchi N., Free PMC Article | 01/16/2021 |
| Interaction proteomics revealed that VGLL3 bound TEAD1, TEAD3 and TEAD4 in myoblasts and/or myotubes. | VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle.
Figeac N, Mohamed AD, Sun C, Schönfelder M, Matallanas D, Garcia-Munoz A, Missiaglia E, Collie-Duguid E, De Mello V, Pobbati AV, Pruller J, Jaka O, Harridge SDR, Hong W, Shipley J, Vargesson N, Zammit PS, Wackerhage H., Free PMC Article | 07/18/2020 |
| VGLL3 is a novel prognostic biomarker of both the clinical outcome and immune infiltration in STAD, and may therefore be a promising therapeutic target. | VGLL3 is a prognostic biomarker and correlated with clinical pathologic features and immune infiltrates in stomach adenocarcinoma.
Zhang L, Li L, Mao Y, Hua D., Free PMC Article | 06/13/2020 |
| this study identified a VGLL3-regulated network as a previously unknown inflammatory pathway that promotes female-biased autoimmunity | A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases.
Liang Y, Tsoi LC, Xing X, Beamer MA, Swindell WR, Sarkar MK, Berthier CC, Stuart PE, Harms PW, Nair RP, Elder JT, Voorhees JJ, Kahlenberg JM, Gudjonsson JE., Free PMC Article | 06/24/2017 |
| VGLL3 is involved in tumor suppressor pathways, a feature that is characterized by the absence of VGLL3 expression in high-grade serous ovarian carcinomas samples. | VGLL3 expression is associated with a tumor suppressor phenotype in epithelial ovarian cancer.
Gambaro K, Quinn MC, Wojnarowicz PM, Arcand SL, de Ladurantaye M, Barrès V, Ripeau JS, Killary AM, Davis EC, Lavoie J, Provencher DM, Mes-Masson AM, Chevrette M, Tonin PN., Free PMC Article | 12/28/2013 |
| vestigial-like 3 (Vgll3) is an inhibitor of adipogenesis | Vestigial-like 3 is an inhibitor of adipocyte differentiation.
Halperin DS, Pan C, Lusis AJ, Tontonoz P., Free PMC Article | 06/8/2013 |
| data suggest that the amplification and overexpression of YAP1 and VGLL3 could be involved in oncogenesis and progression of soft tissue sarcomas | YAP1 and VGLL3, encoding two cofactors of TEAD transcription factors, are amplified and overexpressed in a subset of soft tissue sarcomas.
Hélias-Rodzewicz Z, Pérot G, Chibon F, Ferreira C, Lagarde P, Terrier P, Coindre JM, Aurias A. | 02/5/2011 |
| This protein was named Vestigial-like 3, because it is related to the Drosophila protein Vestigial. Like other members of this family, it contains a consensus TEF-1 and MEF2(TDU)interaction domain. | Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation.
Maeda T, Chapman DL, Stewart AF. | 02/25/2005 |