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    L1CAM L1 cell adhesion molecule [ Homo sapiens (human) ]

    Gene ID: 3897, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Expression of L1 Cell Adhesion Molecule, a Nephronal Principal Cell Marker, in Nephrogenic Adenoma.

    Expression of L1 Cell Adhesion Molecule, a Nephronal Principal Cell Marker, in Nephrogenic Adenoma.
    Mannan R, Wang X, Mahapatra S, Wang S, Chinnaiyan AK, Skala SL, Zhang Y, McMurry LM, Zelenka-Wang S, Cao X, Sangoi AR, Dadhania V, Picken MM, Menon S, Al-Ahmadie H, Chinnaiyan AM, Dhanasekaran SM, Mehra R.,

    08/27/2024
    Reciprocal regulation of forkhead box C1 and L1 cell adhesion molecule contributes to triple-negative breast cancer progression.

    Reciprocal regulation of forkhead box C1 and L1 cell adhesion molecule contributes to triple-negative breast cancer progression.
    Zhang F, Xu Y, Lin J, Pan H, Giuliano AE, Cui X, Cui Y., Free PMC Article

    03/26/2024
    Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma.

    Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma.
    Chien MH, Yang YC, Ho KH, Ding YF, Chen LH, Chiu WK, Chen JQ, Tung MC, Hsiao M, Lee WJ., Free PMC Article

    02/29/2024
    VAMP7j: A Splice Variant of Human VAMP7 That Modulates Neurite Outgrowth by Regulating L1CAM Transport to the Plasma Membrane.

    VAMP7j: A Splice Variant of Human VAMP7 That Modulates Neurite Outgrowth by Regulating L1CAM Transport to the Plasma Membrane.
    Gasparotto M, Dall'Ara E, Vacca M, Filippini F., Free PMC Article

    01/12/2024
    A novel splicing variation in L1CAM is responsible for recurrent fetal hydrocephalus.

    A novel splicing variation in L1CAM is responsible for recurrent fetal hydrocephalus.
    He T, Yao Q, Xu B, Yang M, Jiang J, Xiang Q, Xiao L, Liu S, Wang H, Zhang X., Free PMC Article

    11/22/2023
    L1CAM Is Not a Predictive Factor in Early-stage Squamous-cell Cervical Cancer.

    L1CAM Is Not a Predictive Factor in Early-stage Squamous-cell Cervical Cancer.
    Romanová M, Židlík V, Javůrková V, Kondé A, Šimetka O, Klát J., Free PMC Article

    11/6/2023
    An Increase in Mucin2 Expression Is Required for Colon Cancer Progression Mediated by L1.

    An Increase in Mucin2 Expression Is Required for Colon Cancer Progression Mediated by L1.
    Saha A, Gavert N, Brabletz T, Ben-Ze'ev A., Free PMC Article

    09/19/2023
    Clinical significance of L1CAM expression in metastatic tubo-ovarian high-grade serous carcinoma.

    Clinical significance of L1CAM expression in metastatic tubo-ovarian high-grade serous carcinoma.
    Dos Santos MV, Holth A, Lindemann K, Staff AC, Davidson B.

    09/7/2023
    ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.

    ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
    Li L, Wang X, Hu K, Liu X, Qiu L, Bai C, Cui Y, Wang B, Wang Z, Wang H, Cheng R, Hua J, Hai L, Wang M, Liu M, Song Z, Xiao C, Li B.

    07/3/2023
    Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility.

    Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility.
    Gajendran N, Rajasekaran S, Witt SN., Free PMC Article

    06/15/2023
    Prognostic Value of beta-Catenin and L1CAM Expressions in Type I Endometrial Carcinoma.

    Prognostic Value of β-Catenin and L1CAM Expressions in Type I Endometrial Carcinoma.
    Manule Y, Miskad UA, Masadah R, Nelwan B, Cangara MH, Mardiati M., Free PMC Article

    05/3/2023
    L1-CAM in Mucinous Ovarian Carcinomas and Borderline Tumors: Impact on Tumor Recurrence and Potential Role in Tumor Progression.

    L1-CAM in Mucinous Ovarian Carcinomas and Borderline Tumors: Impact on Tumor Recurrence and Potential Role in Tumor Progression.
    Wiedenhoefer R, Schmoeckel E, Grube M, Sulyok M, Pasternak I, Beschorner C, Greif K, Brucker S, Mayr D, Kommoss S, Fend F, Staebler A, Fischer AK.

    04/19/2023
    L1CAM promotes vasculogenic mimicry formation by miR-143-3p-induced expression of hexokinase 2 in glioma.

    L1CAM promotes vasculogenic mimicry formation by miR-143-3p-induced expression of hexokinase 2 in glioma.
    Huang Y, Zhu C, Liu P, Ouyang F, Luo J, Lu C, Tang B, Yang X., Free PMC Article

    04/15/2023
    Clinical significance of L1CAM expression and its biological role in the progression of oral squamous cell carcinoma.

    Clinical significance of L1CAM expression and its biological role in the progression of oral squamous cell carcinoma.
    Kim JH, Lee KW, Ahn DG, Oh KY, Yoon HJ., Free PMC Article

    02/27/2023
    The KDET Motif in the Intracellular Domain of the Cell Adhesion Molecule L1 Interacts with Several Nuclear, Cytoplasmic, and Mitochondrial Proteins Essential for Neuronal Functions.

    The KDET Motif in the Intracellular Domain of the Cell Adhesion Molecule L1 Interacts with Several Nuclear, Cytoplasmic, and Mitochondrial Proteins Essential for Neuronal Functions.
    Kleene R, Loers G, Schachner M., Free PMC Article

    01/28/2023
    L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary.

    L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary.
    Doberstein K, Spivak R, Reavis HD, Hooda J, Feng Y, Kroeger PT Jr, Stuckelberger S, Mills GB, Devins KM, Schwartz LE, Iwanicki MP, Fogel M, Altevogt P, Drapkin R., Free PMC Article

    12/24/2022
    p53, Pirh2, and L1CAM as Promising Prognostic Biomarkers of Endometrial Carcinoma: An Immunohistochemical and Genetic Study.

    p53, Pirh2, and L1CAM as Promising Prognostic Biomarkers of Endometrial Carcinoma: An Immunohistochemical and Genetic Study.
    Abdelrahman AE, Salem A, Al Attar AZ, Elsebai E, Samy W, Ibrahim MA, Ibrahim HM.

    11/19/2022
    Analysis of L1CAM gene mutation and imaging appearance in three Chinese families with L1 syndrome: Three case reports.

    Analysis of L1CAM gene mutation and imaging appearance in three Chinese families with L1 syndrome: Three case reports.
    Gao S, Zhao X, Zhao G, Dai P, Kong X., Free PMC Article

    10/29/2022
    Expression of L1 Cell Adhesion Molecule (L1CAM) in extracellular vesicles in the human spinal cord during development.

    Expression of L1 Cell Adhesion Molecule (L1CAM) in extracellular vesicles in the human spinal cord during development.
    Cau F, Fanni D, Manchia M, Gerosa C, Piras M, Murru R, Paribello P, Congiu T, Coni P, Pichiri G, Piludu M, Van Eyken P, Gibo Y, La Nasa G, Orrù G, Scano A, Coghe F, Saba L, Castagnola M, Faa G.

    10/15/2022
    Interindividual variability in L1CAM expression in the human kidney during development: are there implications for fetal programming of kidney diseases presenting in adulthood?

    Interindividual variability in L1CAM expression in the human kidney during development: are there implications for fetal programming of kidney diseases presenting in adulthood?
    Cau F, Gerosa C, Murru R, Pichiri G, Coni P, Piras M, Scano A, Orrù G, La Nasa G, Coghe F, Castagnola M, Van Eyken P, Saba L, Fanni D, Faa G.

    07/16/2022
    L1 cell adhesion molecule high expression is associated with poor prognosis in surgically resected brain metastases from lung adenocarcinoma.

    L1 cell adhesion molecule high expression is associated with poor prognosis in surgically resected brain metastases from lung adenocarcinoma.
    Wang JW, Wang SQ, Wu ZY, Liu Q, Yuan Q, Cai HQ, Wan JH., Free PMC Article

    05/28/2022
    L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.

    L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.
    Ganesh K, Basnet H, Kaygusuz Y, Laughney AM, He L, Sharma R, O'Rourke KP, Reuter VP, Huang YH, Turkekul M, Er EE, Masilionis I, Manova-Todorova K, Weiser MR, Saltz LB, Garcia-Aguilar J, Koche R, Lowe SW, Pe'er D, Shia J, Massagué J., Free PMC Article

    04/30/2022
    L1CAM variants cause two distinct imaging phenotypes on fetal MRI.

    L1CAM variants cause two distinct imaging phenotypes on fetal MRI.
    Accogli A, Goergen S, Izzo G, Mankad K, Krajden Haratz K, Parazzini C, Fahey M, Menzies L, Baptista J, Carpineta L, Tortora D, Fulcheri E, Gaetano Vellone V, Paladini D, Spaccini L, Toto V, Trayers C, Ben Sira L, Reches A, Malinger G, Salpietro V, De Marco P, Srour M, Zara F, Capra V, Rossi A, Severino M., Free PMC Article

    04/30/2022
    Role of L1CAM in retinoblastoma tumorigenesis: identification of novel therapeutic targets.

    Role of L1CAM in retinoblastoma tumorigenesis: identification of novel therapeutic targets.
    Dräger O, Metz K, Busch M, Dünker N., Free PMC Article

    04/16/2022
    High-risk endometrial cancer proteomic profiling reveals that FBXW7 mutation alters L1CAM and TGM2 protein levels.

    High-risk endometrial cancer proteomic profiling reveals that FBXW7 mutation alters L1CAM and TGM2 protein levels.
    Urick ME, Yu EJ, Bell DW., Free PMC Article

    03/12/2022
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