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    LHCGR luteinizing hormone/choriogonadotropin receptor [ Homo sapiens (human) ]

    Gene ID: 3973, updated on 12-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Widespread Distribution of Luteinizing Hormone/Choriogonadotropin Receptor in Human Juvenile Angiofibroma: Implications for a Sex-Specific Nasal Tumor.

    Widespread Distribution of Luteinizing Hormone/Choriogonadotropin Receptor in Human Juvenile Angiofibroma: Implications for a Sex-Specific Nasal Tumor.
    Wemmert S, Pyrski M, Pillong L, Linxweiler M, Zufall F, Leinders-Zufall T, Schick B., Free PMC Article

    08/1/2024
    Correlation between LHCGR and NR5A1 genes polymorphism and male infertility risk.

    Correlation between LHCGR and NR5A1 genes polymorphism and male infertility risk.
    Behvarz M, Rahmani SA, Siasi Torbati E, Danaei Mehrabad S, Bikhof Torbati M.

    04/8/2024
    The mystery of transient pregnancy-induced cushing's syndrome: a case report and literature review highlighting GNAS somatic mutations and LHCGR overexpression.

    The mystery of transient pregnancy-induced cushing's syndrome: a case report and literature review highlighting GNAS somatic mutations and LHCGR overexpression.
    Li Y, Lin J, Fu S, Li L, Huang Z, Yang H, Liang X, Qin Y, Zhou J, Liu D, Luo Z.

    02/8/2024
    Significance of LHCGR polymorphisms in polycystic ovary syndrome: an association study.

    Significance of LHCGR polymorphisms in polycystic ovary syndrome: an association study.
    Singh S, Kaur M, Beri A, Kaur A., Free PMC Article

    01/3/2024
    Gonadotropin independent sexual precocity in a Pakistani male infant from an activating mutation in LHCGR gene.

    Gonadotropin independent sexual precocity in a Pakistani male infant from an activating mutation in LHCGR gene.
    Shahid A, Ibrahim MN.

    12/20/2023
    Whole exome sequencing identifies a novel homozygous missense mutation of LHCGR gene in primary infertile women with empty follicle syndrome.

    Whole exome sequencing identifies a novel homozygous missense mutation of LHCGR gene in primary infertile women with empty follicle syndrome.
    Xu Y, Wang E, Liu T, Wang S, Wu F, Zhao X, Wang A.

    10/4/2023
    Post-trigger luteinizing hormone concentration to positively predict oocyte yield in the antagonist protocol and its association with genetic variants of LHCGR.

    Post-trigger luteinizing hormone concentration to positively predict oocyte yield in the antagonist protocol and its association with genetic variants of LHCGR.
    Jin H, Yang H, Zheng J, Zhou J, Yu R., Free PMC Article

    09/28/2023
    Effect Modification of LHCGR Gene Variant (rs2293275) on Clinico-Biochemical Profile, and Levels of Luteinizing Hormone in Polycystic Ovary Syndrome Patients.

    Effect Modification of LHCGR Gene Variant (rs2293275) on Clinico-Biochemical Profile, and Levels of Luteinizing Hormone in Polycystic Ovary Syndrome Patients.
    Makhdoomi MJ, Shah IA, Rashid R, Rashid A, Singh S, Shah ZA, Ganie MA.

    07/27/2023
    Luteinizing hormone receptor promotes angiogenesis in ovarian endothelial cells of Macaca fascicularis and Homo sapiensdagger.

    Luteinizing hormone receptor promotes angiogenesis in ovarian endothelial cells of Macaca fascicularis and Homo sapiens†.
    Lund M, Pearson AC, Sage MAG, Duffy DM., Free PMC Article

    03/10/2023
    Association analysis of LHCGR variants and polycystic ovary syndrome in Punjab: a case-control approach.

    Association analysis of LHCGR variants and polycystic ovary syndrome in Punjab: a case-control approach.
    Singh S, Kaur M, Kaur R, Beri A, Kaur A., Free PMC Article

    03/9/2023
    Novel homozygous inactivating mutation in the luteinizing hormone receptor gene (LHCGR) associated with 46, XY DSD in a Moroccan family.

    Novel homozygous inactivating mutation in the luteinizing hormone receptor gene (LHCGR) associated with 46, XY DSD in a Moroccan family.
    Alla A, Ongoth FEM, Tahiri A, Karrou M, Rouf S, Benhaddou H, Kamaoui I, Mcelreavey K, Latrech H.

    10/29/2022
    Gonadotropin receptor polymorphisms (FSHR N680S and LHCGR N312S) are not predictive of clinical outcome and live birth in assisted reproductive technology.

    Gonadotropin receptor polymorphisms (FSHR N680S and LHCGR N312S) are not predictive of clinical outcome and live birth in assisted reproductive technology.
    Pirtea P, de Ziegler D, Marin D, Sun L, Tao X, Ayoubi JM, Franasiak J, Scott RT Jr.

    10/1/2022
    Expression and function of the luteinizing hormone choriogonadotropin receptor in human endometrial stromal cells.

    Expression and function of the luteinizing hormone choriogonadotropin receptor in human endometrial stromal cells.
    Mann ON, Kong CS, Lucas ES, Brosens JJ, Hanyaloglu AC, Brighton PJ., Free PMC Article

    05/28/2022
    A rare cause of primary amenorrhea: LHCGR gene mutations.

    A rare cause of primary amenorrhea: LHCGR gene mutations.
    Aktar Karakaya A, Çayır A, Unal E, Beştaş A, Ece Solmaz A, Kenan Haspolat Y.

    05/21/2022
    Associations of FSHR and LHCGR gene variants with ovarian reserve and clinical pregnancy rates.

    Associations of FSHR and LHCGR gene variants with ovarian reserve and clinical pregnancy rates.
    Guo C, Yu H, Feng G, Lv Q, Liu X, Liu X.

    02/5/2022
    Molecular study and genotype-phenotype in Chinese female patients with 46, XY disorders of sex development.

    Molecular study and genotype-phenotype in Chinese female patients with 46, XY disorders of sex development.
    Xia J, Wu J, Chen C, Zhao Z, Xie Y, Bai Z, Kong X.

    01/29/2022
    Effect of LHCGR Gene Polymorphism (rs2293275) on LH Supplementation Protocol Outcomes in Second IVF Cycles: A Retrospective Study.

    Effect of LHCGR Gene Polymorphism (rs2293275) on LH Supplementation Protocol Outcomes in Second IVF Cycles: A Retrospective Study.
    Ga R, Cheemakurthi R, Kalagara M, Prathigudupu K, Balabomma KL, Mahapatro P, Thota S, Kommaraju AL, Muvvala SPR., Free PMC Article

    12/18/2021
    A threshold concentration of FSH is needed during IVM of ex vivo collected human oocytes.

    A threshold concentration of FSH is needed during IVM of ex vivo collected human oocytes.
    Cadenas J, Nikiforov D, Pors SE, Zuniga LA, Wakimoto Y, Ghezelayagh Z, Mamsen LS, Kristensen SG, Andersen CY., Free PMC Article

    12/11/2021
    Novel mutations of the LHCGR gene in two families with 46,XY DSD causing Leydig cell hypoplasia I.

    Novel mutations of the LHCGR gene in two families with 46,XY DSD causing Leydig cell hypoplasia I.
    Hassan HA, Essawi ML, Mekkawy MK, Mazen I.

    11/22/2021
    Novel mutations in LHCGR (luteinizing hormone/choriogonadotropin receptor): expanding the spectrum of mutations responsible for human empty follicle syndrome.

    Novel mutations in LHCGR (luteinizing hormone/choriogonadotropin receptor): expanding the spectrum of mutations responsible for human empty follicle syndrome.
    Zhang Z, Wu L, Diao F, Chen B, Fu J, Mao X, Yan Z, Li B, Mu J, Zhou Z, Wang W, Zhao L, Dong J, Zeng Y, Du J, Kuang Y, Sun X, He L, Sang Q, Wang L., Free PMC Article

    06/5/2021
    Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.

    Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.
    Cheung J, Lokman NA, Abraham RD, Macpherson AM, Lee E, Grutzner F, Ghinea N, Oehler MK, Ricciardelli C., Free PMC Article

    03/13/2021
    Candidate genes for age at menarche are associated with endometrial hyperplasia.

    Candidate genes for age at menarche are associated with endometrial hyperplasia.
    Ponomarenko I, Reshetnikov E, Polonikov A, Sorokina I, Yermachenko A, Dvornyk V, Churnosov M.

    08/29/2020
    Of the 15 variants, 3 variants (rs13405728 in LHCGR; rs13429458 in THADA and rs2209972 IDE genes) were found to be associated with PCOS. The association was successfully replicated in an independent cohort. Insilico analysis categorized two variants (rs13429458-THADA and rs2209972-IDE genes) as deleterious.

    Pooled genetic analysis identifies variants that confer enhanced susceptibility to PCOS in Indian ethnicity.
    Vishnubotla DS, Shek AP, Madireddi S.

    06/27/2020
    High expression of LHCGR is associated with Polycystic ovary syndrome.

    Gene Expression in Granulosa Cells From Small Antral Follicles From Women With or Without Polycystic Ovaries.
    Owens LA, Kristensen SG, Lerner A, Christopoulos G, Lavery S, Hanyaloglu AC, Hardy K, Yding Andersen C, Franks S., Free PMC Article

    06/6/2020
    The expression of LH-R mRNA has a positive correlation with oocyte quality in poor responder patients and a negative correlation in non-poor responders. Our study suggests an optimal expression of LH- R mRNA in granulosa cells during controlled ovarian stimulation to obtain good quality oocytes

    Correlation between luteinizing hormone receptor gene expression in human granulosa cells with oocyte quality in poor responder patients undergoing  in vitro fertilization: A cross-sectional study.
    Wiweko B, Satria ML, Mutia K, Iffanolida PA, Harzif AK, Pratama G, Muharam R, Hestiantoro A., Free PMC Article

    06/6/2020
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