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    LMO7 LIM domain 7 [ Homo sapiens (human) ]

    Gene ID: 4008, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Role of LMO7 in cancer (Review).

    Role of LMO7 in cancer (Review).
    Zeng Q, Jiang T, Wang J., Free PMC Article

    07/18/2024
    Immunoreactivity of LMO7 and other molecular markers as potential prognostic factors in oropharyngeal squamous cell carcinoma.

    Immunoreactivity of LMO7 and other molecular markers as potential prognostic factors in oropharyngeal squamous cell carcinoma.
    Israelsson P, Oda H, Öfverman C, Stefansson K, Lindquist D., Free PMC Article

    07/15/2024
    Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis.

    Exosome-transmitted circular RNA circ-LMO7 facilitates the progression of osteosarcoma by regulating miR-21-5p/ARHGAP24 axis.
    Luo A, Liu H, Huang C, Wei S., Free PMC Article

    07/1/2024
    Novel Long Non-Coding RNA (lncRNA) Transcript AL137782.1 Promotes the Migration of Normal Lung Epithelial Cells through Positively Regulating LMO7.

    Novel Long Non-Coding RNA (lncRNA) Transcript AL137782.1 Promotes the Migration of Normal Lung Epithelial Cells through Positively Regulating LMO7.
    Zhang Y, Wang W, Duan C, Li M, Gao L., Free PMC Article

    10/5/2023
    New Findings on LMO7 Transcripts, Proteins and Regulatory Regions in Human and Vertebrate Model Organisms and the Intracellular Distribution in Skeletal Muscle Cells.

    New Findings on LMO7 Transcripts, Proteins and Regulatory Regions in Human and Vertebrate Model Organisms and the Intracellular Distribution in Skeletal Muscle Cells.
    Gomes G, do Amaral MJ, Bagri KM, Vasconcellos LM, Almeida MDS, Alvares LE, Mermelstein C., Free PMC Article

    01/8/2022
    LMO7 and LIMCH1 co-localized and co-immunoprecipitated.

    LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease.
    Karlsson T, Kvarnbrink S, Holmlund C, Botling J, Micke P, Henriksson R, Johansson M, Hedman H.

    08/31/2019
    the LMO7-BRAF fusion behaves as an oncogenic alteration in papillary thyroid carcinoma

    Identification of a Recurrent LMO7-BRAF Fusion in Papillary Thyroid Carcinoma.
    He H, Li W, Yan P, Bundschuh R, Killian JA, Labanowska J, Brock P, Shen R, Heerema NA, de la Chapelle A., Free PMC Article

    05/11/2019
    Data suggest that LMO7 interacts with MAD1 during spindle assembly phase of mitosis; LMO7 plays role in control of mitosis progression and exerts effect on spindle assembly checkpoint; LMO7 colocalizes with actin filaments; LMO7 does not colocalize with MAD1 at kinetochores in prometaphase nor at spindle poles in metaphase. (LMO7 = LIM domain only protein-7; MAD1 = mitotic spindle assembly checkpoint protein MAD1)

    LMO7 exerts an effect on mitosis progression and the spindle assembly checkpoint.
    Tzeng YW, Li DY, Chen Y, Yang CH, Chang CY, Juang YL.

    10/20/2018
    The miR-96-LMO7 axis may be a therapeutic target for lung cancer patients, and new diagnostic or therapeutic strategies could be developed by targeting the miR-96-LMO7 axis.

    Circulating exosomal microRNA-96 promotes cell proliferation, migration and drug resistance by targeting LMO7.
    Wu H, Zhou J, Mei S, Wu D, Mu Z, Chen B, Xie Y, Ye Y, Liu J., Free PMC Article

    02/24/2018
    study suggested that the LMO7 gene may play an important role in the pathogenesis of DCM in the Han Chinese population.

    Association of LIM Domain 7 Gene Polymorphisms and Plasma Levels of LIM Domain 7 with Dilated Cardiomyopathy in a Chinese Population.
    Li C, Peng Y, Zhou B, Bai W, Rao L.

    07/1/2017
    Data suggest that Lmo7 is localized at the perinuclear region and in fibril-like structures along subsarcolemma of human skeletal myoblasts whereas in human myotubes Lmo7 is found diffuse throughout the cytoplasm.

    Knockdown of Lmo7 inhibits chick myogenesis.
    Possidonio AC, Soares CP, Fontenele M, Morris ER, Mouly V, Costa ML, Mermelstein C.

    06/28/2016
    show that LMO7 is upregulated in the stroma of invasive breast carcinoma in a manner that correlates with the increased expression of serum response factor target genes

    LMO7 mediates cell-specific activation of the Rho-myocardin-related transcription factor-serum response factor pathway and plays an important role in breast cancer cell migration.
    Hu Q, Guo C, Li Y, Aronow BJ, Zhang J., Free PMC Article

    11/12/2011
    functional interaction between emerin and Lmo7 is crucial for temporally regulating the expression of key myogenic differentiation genes.

    Emerin inhibits Lmo7 binding to the Pax3 and MyoD promoters and expression of myoblast proliferation genes.
    Dedeic Z, Cetera M, Cohen TV, Holaska JM.

    11/5/2011
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    Lmo7 positively regulates many EDMD-relevant genes (including emerin), and is feedback-regulated by binding to emerin.

    Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes.
    Holaska JM, Rais-Bahrami S, Wilson KL.

    01/21/2010
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