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    MIR190A microRNA 190a [ Homo sapiens (human) ]

    Gene ID: 406965, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling.

    Hsa_circ_0004872 alleviates meningioma progression by sponging miR-190a-3p/PTEN signaling.
    Huang Y, Wu Z, Peng Z, Liu A, Yuan W, Han D, Peng J., Free PMC Article

    03/20/2024
    The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.

    The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.
    Luo QQ, Tian Y, Qu GJ, Huang K, Hu PP, Xue Y, Hu BF, Luo SS.

    03/1/2024
    Long non-coding RNA ZFAS1 regulates cell proliferation and invasion in cervical cancer via the miR-190a-3p/KLF6 axis.

    Long non-coding RNA ZFAS1 regulates cell proliferation and invasion in cervical cancer via the miR-190a-3p/KLF6 axis.
    Su Y, Hou W, Zhang C, Ji P, Hu R, Zhang Q, Wang Y, Li P, Zhang H, Chen Y, Zhang X, Zhang M., Free PMC Article

    04/16/2022
    MiR-190b impedes pancreatic beta cell proliferation and insulin secretion by targeting NKX6-1 and may associate to gestational diabetes mellitus.

    MiR-190b impedes pancreatic β cell proliferation and insulin secretion by targeting NKX6-1 and may associate to gestational diabetes mellitus.
    Wang S, Wei D, Sun X, Li Y, Li D, Chen B.

    12/25/2021
    circCDYL Acts as a Tumor Suppressor in Triple Negative Breast Cancer by Sponging miR-190a-3p and Upregulating TP53INP1.

    circCDYL Acts as a Tumor Suppressor in Triple Negative Breast Cancer by Sponging miR-190a-3p and Upregulating TP53INP1.
    Wang S, Liu F, Ma H, Cui X, Yang S, Qin R.

    11/6/2021
    Expression and diagnostic value of circulating miRNA-190 and miRNA-197 in patients with pulmonary thromboembolism.

    Expression and diagnostic value of circulating miRNA-190 and miRNA-197 in patients with pulmonary thromboembolism.
    Zhou X, Wu Q, Hao T, Xu R, Hu X, Dong L., Free PMC Article

    10/23/2021
    Inhibition of CUB and sushi multiple domains 1 (CSMD1) expression by miRNA-190a-3p enhances hypertrophic scar-derived fibroblast migration in vitro.

    Inhibition of CUB and sushi multiple domains 1 (CSMD1) expression by miRNA-190a-3p enhances hypertrophic scar-derived fibroblast migration in vitro.
    Gu S, Huang X, Xu X, Liu Y, Khoong Y, Zhang Z, Li H, Gao Y, Zan T., Free PMC Article

    09/18/2021
    Cells introduced with the miR-190 activators along with small interfering RNA-STC2 inhibited proliferation.

    Overexpression of microRNA-190 inhibits migration, invasion, epithelial-mesenchymal transition, and angiogenesis through suppression of protein kinase B-extracellular signal-regulated kinase signaling pathway via binding to stanniocalicin 2 in breast cancer.
    Sun G, Liu M, Han H.

    05/23/2020
    MIRN190 is over-expressed in Wilms' tumor and promoted cell proliferation, invasion and migration.

    Up-regulation of miR-190b promoted growth, invasion, migration and inhibited apoptosis of Wilms' tumor cells by repressing the PTEN expression.
    An NN, Shawn J, Peng JP, Wu MD, Huang LG.

    11/9/2019
    miR-190 promotes hepatocellular carcinoma cell proliferation and metastasis by targeting PHLPP1.

    miR-190 promotes HCC proliferation and metastasis by targeting PHLPP1.
    Xiong Y, Wu S, Yu H, Wu J, Wang Y, Li H, Huang H, Zhang H.

    09/21/2019
    Three HPV16 oncoproteins (E5, E6, and E7) downregulate miR-148a-3p, while E6/E7 inhibit miR-199b-5p and miR-190a-5p expression in cervical carcinoma. The three microRNAs, miR-148a-3p, miR-199b-5p, and miR-190a-5p, may be novel diagnostic biomarkers for cervical cancer development in high-risk HPV-positive patients.

    Human Papillomavirus 16 Oncoproteins Downregulate the Expression of miR-148a-3p, miR-190a-5p, and miR-199b-5p in Cervical Cancer.
    Han MS, Lee JM, Kim SN, Kim JH, Kim HS., Free PMC Article

    04/27/2019
    miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 expression in endothelial cells.

    miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension.
    Jiang J, Xia Y, Liang Y, Yang M, Zeng W, Zeng X., Free PMC Article

    04/13/2019
    Our data uncover the ZEB1/ERalpha-miR-190-SOX9 axis and suggest a mechanism by which the Wnt/beta-catenin signaling pathway is involved in breast cancer anti-estrogen therapy.

    miR-190 enhances endocrine therapy sensitivity by regulating SOX9 expression in breast cancer.
    Yu Y, Yin W, Yu ZH, Zhou YJ, Chi JR, Ge J, Cao XC., Free PMC Article

    04/13/2019
    Our data uncover the ZEB1-miR-190-SMAD2 axis and provide a mechanism to explain the TGF-beta network in breast cancer metastasis.

    miR-190 suppresses breast cancer metastasis by regulation of TGF-β-induced epithelial-mesenchymal transition.
    Yu Y, Luo W, Yang ZJ, Chi JR, Li YR, Ding Y, Ge J, Wang X, Cao XC., Free PMC Article

    01/19/2019
    High miR190 expression is associated with pulmonary hypertension.

    Hypoxia-induced changes in plasma micro-RNAs correlate with pulmonary artery pressure at high altitude.
    Blissenbach B, Nakas CT, Krönke M, Geiser T, Merz TM, Pichler Hefti J.

    01/12/2019
    PVT1-miR-190a-5p/miR-488-3p-MEF2C-JAGGED1 axis is involved in proliferation and progression of glioma. Thus, PVT1 may become a novel target in glioma therapy.

    PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p.
    Xue W, Chen J, Liu X, Gong W, Zheng J, Guo X, Liu Y, Liu L, Ma J, Wang P, Li Z, Xue Y.

    07/14/2018
    Data confirm that a combination of serum expression levels of microRNA-95 and microRNA-190 is an accurate and non-invasive tool for differential diagnosis of thyroid nodules in an Italian population.

    Diagnostic Value of Circulating microRNA-95 and -190 in the Differential Diagnosis of Thyroid Nodules: A Validation Study in 1000 Consecutive Patients.
    Pilli T, Cantara S, Marzocchi C, Cardinale S, Santini C, Cevenini G, Pacini F.

    05/5/2018
    These findings identified a biochemical and functional link between miR-190a with reduced expression in advanced prostate cancer, YB-1 and AR signaling in prostate cancer.

    The inhibitory effects of AR/miR-190a/YB-1 negative feedback loop on prostate cancer and underlying mechanism.
    Xu S, Wang T, Song W, Jiang T, Zhang F, Yin Y, Jiang SW, Wu K, Yu Z, Wang C, Chen K., Free PMC Article

    09/17/2016
    Data suggest that suppression of treRNA (translation regulatory long non-coding RNA) by microRNA-190a leads to down-regulation of mesenchymal-epithelial transition and of cell migration/neoplastic invasiveness of hepatoma cells.

    miR-190a inhibits epithelial-mesenchymal transition of hepatoma cells via targeting the long non-coding RNA treRNA.
    Wang X, Ren Y, Yang X, Xiong X, Han S, Ge Y, Pan W, Zhou L, Yuan Q, Yang M.

    05/14/2016
    miR-190 affects vascular tone and calcium influx into Smooth muscle cells via targeting Kthorn-channel KCNQ5 in Pulmonary arterial hypertension.

    MicroRNAs in pulmonary arterial hypertension: pathogenesis, diagnosis and treatment.
    Bienertova-Vasku J, Novak J, Vasku A.

    12/19/2015
    The miR-190 mediated effects rely on an extensive network of molecular changes in tumor cells and affects several transcriptional factors, tumor suppressor genes and interferon response pathways.

    Transcriptional changes induced by the tumor dormancy-associated microRNA-190.
    Almog N, Briggs C, Beheshti A, Ma L, Wilkie KP, Rietman E, Hlatky L., Free PMC Article

    04/4/2015
    High mIR190 expression is associated with insulin resistance in hepatocellular carcinoma.

    Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma.
    Hung TM, Ho CM, Liu YC, Lee JL, Liao YR, Wu YM, Ho MC, Chen CH, Lai HS, Lee PH., Free PMC Article

    01/31/2015
    Epstein-Barr Virus utilizes a cellular mir-190 to promote host cell survival and prevent virus from entering lytic life cycle for latency maintenance.

    miR-190 is upregulated in Epstein-Barr Virus type I latency and modulates cellular mRNAs involved in cell survival and viral reactivation.
    Cramer EM, Shao Y, Wang Y, Yuan Y.

    01/17/2015
    We have identified for the first time two miRNAs, mir-95 and mir-190, differently expressed in serum of papillary thyroid cancer patients who in combination allow the differential diagnosis of thyroid nodules with great accuracy in our study population

    Circulating miRNA95 and miRNA190 are sensitive markers for the differential diagnosis of thyroid nodules in a Caucasian population.
    Cantara S, Pilli T, Sebastiani G, Cevenini G, Busonero G, Cardinale S, Dotta F, Pacini F.

    01/17/2015
    Levels of miRNA-93, 190, and 200b were not significantly different in core biopsies of locally advanced breast cancer patients with different HER2 expressions.

    Association of microRNA-93, 190, 200b and receptor status in core biopsies from stage III breast cancer patients.
    Kolacinska A, Morawiec J, Pawlowska Z, Szemraj J, Szymanska B, Malachowska B, Morawiec Z, Morawiec-Sztandera A, Pakula L, Kubiak R, Zawlik I., Free PMC Article

    11/8/2014
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