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    MIR30D microRNA 30d [ Homo sapiens (human) ]

    Gene ID: 407033, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miR-30d-5p inhibits proliferation, invasion and migration of breast cancer cells by targeting SERPINE1 and promoting fatty acid beta-oxidation.

    miR-30d-5p inhibits proliferation, invasion and migration of breast cancer cells by targeting SERPINE1 and promoting fatty acid β-oxidation.
    Zhang L, Ren S, Sang Y, Hu Y, Wang C, Wang X, Li Y., Free PMC Article

    05/7/2024
    MicroRNA-30d and -483-3p for bi-ventricular remodelling and miR-126-3p for pulmonary hypertension in advanced heart failure.

    MicroRNA-30d and -483-3p for bi-ventricular remodelling and miR-126-3p for pulmonary hypertension in advanced heart failure.
    Gallo A, Agnese V, Sciacca S, Scardulla C, Cipriani M, Pilato M, Oh JK, Pasta S, Maalouf J, Conaldi PG, Bellavia D., Free PMC Article

    02/2/2024
    Blood exosome marker miRNA-30d-5p: Role and regulation mechanism in cell stemness and gemcitabine resistance of hepatocellular carcinoma.

    Blood exosome marker miRNA-30d-5p: Role and regulation mechanism in cell stemness and gemcitabine resistance of hepatocellular carcinoma.
    Tang B, Xie L, Tang X, Tian J, Xiao S.

    10/30/2023
    LncRNA LINC02535 Induces Colorectal Adenocarcinoma Progression via Modulating miR-30d-5p/CHD1.

    LncRNA LINC02535 Induces Colorectal Adenocarcinoma Progression via Modulating miR-30d-5p/CHD1.
    Li J, Xu J, Zheng S, Cheng S.

    07/19/2023
    Contribution of microRNA-30d to the prevention of the thyroid cancer occurrence and progression: mechanism and implications.

    Contribution of microRNA-30d to the prevention of the thyroid cancer occurrence and progression: mechanism and implications.
    Li Y, He Y, Chen Y, He Z, Yang F, Xing C.

    04/21/2023
    Targeting miR-30d reverses pathological cardiac hypertrophy.

    Targeting miR-30d reverses pathological cardiac hypertrophy.
    Li J, Sha Z, Zhu X, Xu W, Yuan W, Yang T, Jin B, Yan Y, Chen R, Wang S, Yao J, Xu J, Wang Z, Li G, Das S, Yang L, Xiao J., Free PMC Article

    07/30/2022
    Construction of a lncRNA/pseudogene-hsa-miR-30d-5p-GJA1 regulatory network related to metastasis of pancreatic cancer.

    Construction of a lncRNA/pseudogene-hsa-miR-30d-5p-GJA1 regulatory network related to metastasis of pancreatic cancer.
    Zheng H, Ding B, Xue K, Yu J, Lou W.

    04/9/2022
    LncRNA DDX11 antisense RNA 1 promotes EMT process of esophageal squamous cell carcinoma by sponging miR-30d-5p to regulate SNAI1/ZEB2 expression and Wnt/beta-catenin pathway.

    LncRNA DDX11 antisense RNA 1 promotes EMT process of esophageal squamous cell carcinoma by sponging miR-30d-5p to regulate SNAI1/ZEB2 expression and Wnt/β-catenin pathway.
    Guo Y, Sun P, Guo W, Yin Q, Han J, Sheng S, Liang J, Dong Z., Free PMC Article

    02/19/2022
    Expression and significance of miR-30d-5p and SOCS1 in patients with recurrent implantation failure during implantation window.

    Expression and significance of miR-30d-5p and SOCS1 in patients with recurrent implantation failure during implantation window.
    Zhao Y, He D, Zeng H, Luo J, Yang S, Chen J, Abdullah RK, Liu N., Free PMC Article

    01/29/2022
    Down-regulation of microRNA-30d-5p is associated with gestational diabetes mellitus by targeting RAB8A.

    Down-regulation of microRNA-30d-5p is associated with gestational diabetes mellitus by targeting RAB8A.
    Zhang L, Li K, Tian S, Wang XQ, Li JH, Dong YC, Xia HF, Ma X.

    01/15/2022
    CircPVT1 promotes proliferation of lung squamous cell carcinoma by binding to miR-30d/e.

    CircPVT1 promotes proliferation of lung squamous cell carcinoma by binding to miR-30d/e.
    Shi J, Lv X, Zeng L, Li W, Zhong Y, Yuan J, Deng S, Liu B, Yuan B, Chen Y, Ming Z, Yang X, Fang P, Yang S, Chen G., Free PMC Article

    01/1/2022
    circCD151 promotes GLI2 expression by regulating miR30d5p and enhancing proliferation, invasion and stemness of lung cancer.

    circCD151 promotes GLI2 expression by regulating miR‑30d‑5p and enhancing proliferation, invasion and stemness of lung cancer.
    Zhao L, Zheng H, Jiang P., Free PMC Article

    12/25/2021
    Investigation the Role of Autophagy in Non-Small Cell Lung Cancer.

    Investigation the Role of Autophagy in Non-Small Cell Lung Cancer.
    Pargol M, Zare Karizi S, Akbari M, Nourmohammadi B, Shadmehr MB, Karimipoor M, Zare Karizi S., Free PMC Article

    11/22/2021
    Up-regulation of microRNA-30b/30d cluster represses hepatocyte apoptosis in mice with fulminant hepatic failure by inhibiting CEACAM1.

    Up-regulation of microRNA-30b/30d cluster represses hepatocyte apoptosis in mice with fulminant hepatic failure by inhibiting CEACAM1.
    Zhao C, Dang Z, Sun J, Yuan S, Xie L.

    11/13/2021
    Down-Regulation of microRNA-30d Alleviates Intervertebral Disc Degeneration Through the Promotion of FOXO3 and Suppression of CXCL10.

    Down-Regulation of microRNA-30d Alleviates Intervertebral Disc Degeneration Through the Promotion of FOXO3 and Suppression of CXCL10.
    Xia P, Gao X, Li F, Shao L, Sun Y.

    07/31/2021
    Involvement of miR-30a-5p and miR-30d in Endothelial to Mesenchymal Transition and Early Osteogenic Commitment under Inflammatory Stress in HUVEC.

    Involvement of miR-30a-5p and miR-30d in Endothelial to Mesenchymal Transition and Early Osteogenic Commitment under Inflammatory Stress in HUVEC.
    Ciavarella C, Motta I, Vasuri F, Fittipaldi S, Valente S, Pollutri D, Ricci F, Gargiulo M, Pasquinelli G., Free PMC Article

    07/3/2021
    Piperlongumine inhibits the progression of osteosarcoma by downregulating the SOCS3/JAK2/STAT3 pathway via miR-30d-5p.

    Piperlongumine inhibits the progression of osteosarcoma by downregulating the SOCS3/JAK2/STAT3 pathway via miR-30d-5p.
    Hu Y, Luo X, Zhou J, Chen S, Gong M, Deng Y, Zhang H.

    06/26/2021
    Long noncoding RNA POU3F3 enhances cancer cell proliferation, migration and invasion in non-small cell lung cancer (adenocarcinoma) by downregulating microRNA-30d-5p.

    Long noncoding RNA POU3F3 enhances cancer cell proliferation, migration and invasion in non-small cell lung cancer (adenocarcinoma) by downregulating microRNA-30d-5p.
    Zeng Q, Dai Y, Duan C, Zeng R, Zeng Q, Wei C., Free PMC Article

    05/1/2021
    [microRNA-30d can inhibit the proliferation, migration and invasion of human mesothelial cell MSTO-211H].

    [microRNA-30d can inhibit the proliferation, migration and invasion of human mesothelial cell MSTO-211H].
    Yuan XY, Zhang FF, Huang YL, Jia ZY, Ju L, Xiao Y, Xia HL, Gao YN, Yu M, Yu M, Zhang X, Zhu LJ.

    03/20/2021
    A novel long noncoding RNA, LOC440173, promotes the progression of esophageal squamous cell carcinoma by modulating the miR-30d-5p/HDAC9 axis and the epithelial-mesenchymal transition.

    A novel long noncoding RNA, LOC440173, promotes the progression of esophageal squamous cell carcinoma by modulating the miR-30d-5p/HDAC9 axis and the epithelial-mesenchymal transition.
    Wang G, Feng B, Niu Y, Wu J, Yang Y, Shen S, Guo Y, Liang J, Guo W, Dong Z.

    01/23/2021
    Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.

    Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.
    Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V, Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D, Bossi F, Lees J, Alon N, Brunga L, Malkin D, Piazza S, Collavin L, Rosato A, Bicciato S, Tripodo C, Mantovani F, Del Sal G., Free PMC Article

    09/26/2020
    GLDC is the post-transcriptional target of miR-30d-5p. GLDC overexpression could rescue miR-30d-5p-mediated cell metastasis and increase autophagy.

    Glycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma.
    Zhuang H, Wu F, Wei W, Dang Y, Yang B, Ma X, Han F, Li Y., Free PMC Article

    04/25/2020
    In this study, both ARID4A and ARID4B were identified as the target genes of miR-30d.

    Downregulation of ARID4A and ARID4B promote tumor progression and directly regulated by microRNA-30d in patient with prostate cancer.
    Liang YK, Han ZD, Lu JM, Liu ZZ, Zhuo YJ, Zhu XJ, Chen JX, Ye JH, Liang YX, He HC, Zhong WD.

    10/26/2019
    microRNA-30d mediated breast cancer invasion, migration, and epithelial-mesenchymal transition by targeting KLF11 and activating STAT3 pathway.

    microRNA-30d mediated breast cancer invasion, migration, and EMT by targeting KLF11 and activating STAT3 pathway.
    Han M, Wang Y, Guo G, Li L, Dou D, Ge X, Lv P, Wang F, Gu Y.

    10/12/2019
    DGCR5 negatively regulates miR-30d-5p, and it up-regulates Runx2 through miR-30d-5p, thereby inducing osteogenic differentiation of hMSCs, which may help to delay Postmenopausal osteoporosis development.

    DGCR5 induces osteogenic differentiation by up-regulating Runx2 through miR-30d-5p.
    Wu ZH, Huang KH, Liu K, Wang GT, Sun Q.

    05/25/2019
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