TGF-β1/SMAD3-driven GLI2 isoform expression contributes to aggressive phenotypes of hepatocellular carcinoma.
Ding J, Yang YY, Li PT, Ma Y, Zhang L, Zhou Y, Jin C, Li HY, Zhu YF, Liu XP, Liu ZJ, Jia HL, Liu PG, Wu J.

Linc00673-V3 positively regulates autophagy by promoting Smad3-mediated LC3B transcription in NSCLC.
Ni H, Tang S, Lu G, Niu Y, Xu J, Zhang H, Hu J, Shen HM, Wu Y, Xia D., Free PMC Article

DUSP22 Ameliorates Endothelial-to-Mesenchymal Transition in HUVECs through Smad2/3 and MAPK Signaling Pathways.
Chen L, Su H, Tao Z, Liang C, Liu Z, Dong Y, Zheng P, Liu Y., Free PMC Article

Single-cell transcriptomic sequencing data reveal aberrant DNA methylation in SMAD3 promoter region in tumor-associated fibroblasts affecting molecular mechanism of radiosensitivity in non-small cell lung cancer.
Han F, Chen S, Zhang K, Zhang K, Wang M, Wang P., Free PMC Article

Sex-specific increases in myostatin and SMAD3 contribute to obesity-related insulin resistance in human skeletal muscle and primary human myotubes.
Saxena G, Gallagher S, Law TD, Maschari D, Walsh E, Dudley C, Brault JJ, Consitt LA.

Therapeutic potential for renal fibrosis by targeting Smad3-dependent noncoding RNAs.
Gu YY, Liu XS, Lan HY.,

The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation.
Motizuki M, Yokoyama T, Saitoh M, Miyazawa K., Free PMC Article

POH1 induces Smad3 deubiquitination and promotes lung cancer metastasis.
Yuan Y, Li Y, Wu X, Bo J, Zhang L, Zhang J, Hu Y, Chen Y, Zeng Y, Wei X, Zhang H.

BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.
Feng Y, Cai L, Pook M, Liu F, Chang CH, Mouti MA, Nibhani R, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Wang C, Hong W, Morgan H, Wang M, Sadayappan S, Jegga AG, Oppermann U, Wang Y, Huang W, Jiang L, Pauklin S.

Circular RNA MTCL1 targets SMAD3 by sponging miR-145-5p for regulation of cell proliferation and migration in Hirschsprung's disease.
Chen W, Caiyun L, Yang Y, Xinwei H, Nan L, Jiaming Y, Huirong Y, Kai W, Liucheng Y.

A novel pathogenic variant located just upstream of the C-terminal Ser423-X-Ser425 phosphorylation motif in SMAD3 causing Loeys-Dietz syndrome.
Ishii S, Fujiwara T, Yagi H, Takeda N, Ando M, Yamauchi H, Inuzuka R, Taniguchi Y, Hatano M, Komuro I., Free PMC Article

m(6)A-modified miR-143-3p inhibits epithelial mesenchymal transition in bronchial epithelial cells and extracellular matrix production in lung fibroblasts by targeting Smad3.
Wang J, Jian Q, Yan K, Yang J, Yan L, Cheng W.

Jagged1 intracellular domain/SMAD3 complex transcriptionally regulates TWIST1 to drive glioma invasion.
Kim JY, Hong N, Park S, Ham SW, Kim EJ, Kim SO, Jang J, Kim Y, Kim JK, Kim SC, Park JW, Kim H., Free PMC Article

A negative feedback loop centered on SMAD3 expression in transforming growth factor β1-induced corneal myofibroblast differentiation.
Tang Y, Du E, Wang G, Qin F, Meng Z, Dai L, Wang Y, Ren S.

[Silencing of SMAD family member 3 promotes M2 polarization of macrophages and the expression of SMAD7 in rheumatoid arthritis].
Fei C, Shen X, Wan L, Fan H, Liu T, Li M, Liu L, Ge Y, Wang Q, Fan W, Zhou Q.

A potential requirement for Smad3 phosphorylation in Notch-mediated EMT in colon cancer.
Clark AG, Bertrand FE, Sigounas G.

circEIF3I facilitates the recruitment of SMAD3 to early endosomes to promote TGF-β signalling pathway-mediated activation of MMPs in pancreatic cancer.
Zhao Z, Yang W, Kong R, Zhang Y, Li L, Song Z, Chen H, Luo Y, Zhang T, Cheng C, Li G, Liu D, Geng X, Chen H, Wang Y, Pan S, Hu J, Sun B., Free PMC Article

GDF-11 downregulates placental human chorionic gonadotropin expression by activating SMAD2/3 signaling.
Wu Z, Zhang L, Jia Y, Bi B, Fang L, Cheng JC., Free PMC Article

Hsa_circ_0088036 promotes nonsmall cell lung cancer progression by regulating miR-1343-3p/Bcl-3 axis through TGFβ/Smad3/EMT signaling.
Ge P, Chen X, Liu J, Jing R, Zhang X, Li H.

Analysis of intronic SNP (rs4147358) and expression of SMAD3 gene in Atopic Dermatitis: A case-control study.
Shafi T, Rasool R, Ayub S, Bhat IA, Gull A, Hussain S, Hassan Shah I, Shah ZA.

NamiRNA-enhancer network of miR-492 activates the NR2C1-TGF-β/Smad3 pathway to promote epithelial-mesenchymal transition of pancreatic cancer.
Liu S, He X, Di Y, Li Q, Li F, Ma Y, Chen L, Gao Y, Xu J, Yang S, Xu L, Corpe C, Ling Y, Zhang X, Xu J, Yu W, Wang J.

Upregulated TGF-β1 contributes to hyperglycaemia in type 2 diabetes by potentiating glucagon signalling.
Xiao Y, Wang Y, Ryu J, Liu W, Zou H, Zhang R, Yan Y, Dai Z, Zhang D, Sun LZ, Liu F, Zhou Z, Dong LQ.

SMAD3 promotes expression and activity of the androgen receptor in prostate cancer.
Jeon HY, Pornour M, Ryu H, Khadka S, Xu R, Jang J, Li D, Chen H, Hussain A, Fazli L, Gleave M, Dong X, Huang F, Wang Q, Barbieri C, Qi J., Free PMC Article

3D collagen migration patterns reveal a SMAD3-dependent and TGF-β1-independent mechanism of recruitment for tumour-associated fibroblasts in lung adenocarcinoma.
Juste-Lanas Y, Díaz-Valdivia N, Llorente A, Ikemori R, Bernardo A, Arshakyan M, Borau C, Ramírez J, Ruffinelli JC, Nadal E, Reguart N, García-Aznar JM, Alcaraz J., Free PMC Article

The paracaspase MALT1 is a downstream target of Smad3 and potentiates the crosstalk between TGF-β and NF-kB signaling pathways in cancer cells.
Mazi FA, Cakiroglu E, Uysal M, Kalyoncu M, Demirci D, Sozeri PYG, Yilmaz GO, Ozhan SE, Senturk S.