TIF1gamma and SMAD4 regulation in colorectal cancer: impact on cell proliferation and liver metastasis. | TIF1γ and SMAD4 regulation in colorectal cancer: impact on cell proliferation and liver metastasis. Wu Y, Yu B, Ai X, Zhang W, Chen W, Laurence A, Zhang M, Chen Q, Shao Y, Zhang B. | 04/2/2024 |
FLRT3 and TGF-beta/SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia. | FLRT3 and TGF-β/SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia. Pang Y, Xu Y, Chen Q, Cheng K, Ling Y, Jang J, Ge J, Zhu W., Free PMC Article | 03/25/2024 |
LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4. | LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4. Li Z, Ma Z, Wang S, Yan Q, Zhuang H, Zhou Z, Liu C, Chen Y, Han M, Wu Z, Huang S, Zhou Q, Hou B, Zhang C., Free PMC Article | 03/22/2024 |
Epidermal Growth Factor-Like Repeats and Discoidin I-Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination. | Epidermal Growth Factor-Like Repeats and Discoidin I-Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination. Zhao M, Zheng Z, Peng S, Xu Y, Zhang J, Liu J, Pan W, Yin Z, Xu S, Wei C, Wang M, Wan J, Qin JJ., Free PMC Article | 03/20/2024 |
Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast. | Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast. Xu P, Yi Y, Xiong L, Luo Y, Xie C, Luo D, Zeng Z, Liu A. | 12/15/2023 |
Functional filter for whole-genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants >5 kb from coding DNA. | Functional filter for whole-genome sequencing data identifies HHT and stress-associated non-coding SMAD4 polyadenylation site variants >5 kb from coding DNA. Xiao S, Kai Z, Murphy D, Li D, Patel D, Bielowka AM, Bernabeu-Herrero ME, Abdulmogith A, Mumford AD, Westbury SK, Aldred MA, Vargesson N, Caulfield MJ, Genomics England Research Consortium, Shovlin CL., Free PMC Article | 12/5/2023 |
Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway. | Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway. Ma C, Liu M, Feng W, Rao H, Zhang W, Liu C, Xu Y, Wang Z, Teng Y, Yang X, Ni L, Xu J, Gao WQ, Lu B, Li L., Free PMC Article | 11/18/2023 |
SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma. | SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma. Foley K, Shorthouse D, Rahrmann E, Zhuang L, Devonshire G, Gilbertson RJ, OCCAMS consortium, Fitzgerald RC, Hall BA. | 11/16/2023 |
Impact of Smad4 and p53 mutations on the prognosis of patients with pancreatic ductal adenocarcinoma undergoing chemotherapy. | Impact of Smad4 and p53 mutations on the prognosis of patients with pancreatic ductal adenocarcinoma undergoing chemotherapy. Kamata K, Takenaka M, Nishida N, Hara A, Otsuka Y, Tanaka H, Omoto S, Minaga K, Yamao K, Chiba Y, Sakai K, Nishio K, Watanabe T, Kudo M. | 11/6/2023 |
PRMT5 methylating SMAD4 activates TGF-beta signaling and promotes colorectal cancer metastasis. | PRMT5 methylating SMAD4 activates TGF-β signaling and promotes colorectal cancer metastasis. Liu A, Yu C, Qiu C, Wu Q, Huang C, Li X, She X, Wan K, Liu L, Li M, Wang Z, Chen Y, Hu F, Song D, Li K, Zhao C, Deng H, Sun X, Xu F, Lai S, Luo X, Hu J, Wang G. | 10/20/2023 |
SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer. | SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer. Wu C, Zhu X, Dai Q, Chu Z, Yang S, Dong Z. | 09/13/2023 |
Are SMAD2/4/7 genetic variants associated with rheumatoid arthritis susceptibility and severity? | Are SMAD2/4/7 genetic variants associated with rheumatoid arthritis susceptibility and severity? Wajda A, Stypińska B, Czarnecka M, Hasan D, Jarończyk M, Haładyj E, Romanowska-Próchnicka K, Olesińska M, Pawlik A, Paradowska-Gorycka A. | 09/12/2023 |
SMAD4 regulates the progression of cholangiocarcinoma by modulating the expression of STING1. | SMAD4 regulates the progression of cholangiocarcinoma by modulating the expression of STING1. Shi AD, Zhao LM, Sheng GL, Zhang GN, Tang YC, Li KS, Zhang ZL., Free PMC Article | 09/1/2023 |
Methylation status, mRNA and protein expression of the SMAD4 gene in patients with non-melanocytic skin cancers. | Methylation status, mRNA and protein expression of the SMAD4 gene in patients with non-melanocytic skin cancers. Gürsel Ürün Y, Budak M, Usturalı Keskin E. | 08/30/2023 |
TGF-betaRII/EP300/SMAD4 cascade signaling pathway promotes invasion and glycolysis in oral squamous cell carcinoma. | TGF-βRII/EP300/SMAD4 cascade signaling pathway promotes invasion and glycolysis in oral squamous cell carcinoma. Zhang D, Peng Y, Lin G, Xiao Q, Liu H, Nan X, Han J, Zhao R, Wang Y, Liu J, Liu Y. | 07/19/2023 |
KRAS mutation-induced EndMT of brain arteriovenous malformation is mediated through the TGF-beta/BMP-SMAD4 pathway. | KRAS mutation-induced EndMT of brain arteriovenous malformation is mediated through the TGF-β/BMP-SMAD4 pathway. Xu H, Huo R, Li H, Jiao Y, Weng J, Wang J, Yan Z, Zhang J, Zhao S, He Q, Sun Y, Wang S, Cao Y., Free PMC Article | 06/26/2023 |
SMAD4 Expression in Monocytes as a Potential Biomarker for Atherosclerosis Risk in Patients with Obstructive Sleep Apnea. | SMAD4 Expression in Monocytes as a Potential Biomarker for Atherosclerosis Risk in Patients with Obstructive Sleep Apnea. Díaz-García E, García-Sánchez A, Sánz-Rubio D, Alfaro E, López-Fernández C, Casitas R, Mañas Baena E, Cano-Pumarega I, Cubero P, Marin-Oto M, López-Collazo E, Marin JM, García-Río F, Cubillos-Zapata C., Free PMC Article | 05/19/2023 |
Loss of function SMAD4 nonstop mutations in human cancer. | Loss of function SMAD4 nonstop mutations in human cancer. Bauer AH, Basta DW, Hornick JL, Dong F. | 05/17/2023 |
Hereditary haemorrhagic telangiectasia in Danish patients with pathogenic variants in SMAD4: a nationwide study. | Hereditary haemorrhagic telangiectasia in Danish patients with pathogenic variants in SMAD4: a nationwide study. Jelsig AM, Kjeldsen A, Christensen LL, Bertelsen B, Karstensen JG, Brusgaard K, Torring PM. | 04/26/2023 |
SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS. | SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS. Lin X, Pang Q, Hu J, Sun J, Dai S, Yu Y, Xu J., Free PMC Article | 04/19/2023 |
A novel germline SMAD4 variant detected in a Japanese family with juvenile polyposis syndrome and hereditary hemorrhagic telangiectasia. | A novel germline SMAD4 variant detected in a Japanese family with juvenile polyposis syndrome and hereditary hemorrhagic telangiectasia. Kananazawa Y, Yamada T, Yamaguchi T, Saito Y, Kakinuma D, Masuda Y, Ando F, Ohashi R, Eguchi H, Okazaki Y, Ishida H, Yoshida H. | 03/9/2023 |
Review of the Pathologic Characteristics in Myhre Syndrome: Gain-of-Function Pathogenic Variants in SMAD4 cause a Multisystem Fibroproliferative Response. | Review of the Pathologic Characteristics in Myhre Syndrome: Gain-of-Function Pathogenic Variants in SMAD4 cause a Multisystem Fibroproliferative Response. Starr LJ, Lindsay ME, Perry D, Gheewalla G, VanderLaan PA, Majid A, Strange C, Costea GC, Lungu A, Lin AE. | 03/3/2023 |
TGFbeta1 rs1800469 and SMAD4 rs10502913 polymorphisms and genetic susceptibility to colorectal cancer in Bangladeshi population. | TGFβ1 rs1800469 and SMAD4 rs10502913 polymorphisms and genetic susceptibility to colorectal cancer in Bangladeshi population. Sultana TN, Chaity NI, Hasan MM, Shrabonee II, Rivu SF, Aziz MA, Sahaba SA, Apu MNH, Nahid NA, Islam MS, Islam MS. | 02/11/2023 |
Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation. | Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation. Dijkstra JJ, Neikes HK, Rezaeifard S, Ma X, Voest EE, Tauriello DVF, Vermeulen M., Free PMC Article | 01/14/2023 |
SMAD4 loss-of-function mutation predisposes to congenital heart disease. | SMAD4 loss-of-function mutation predisposes to congenital heart disease. Wang Y, Xu YJ, Yang CX, Huang RT, Xue S, Yuan F, Yang YQ. | 12/31/2022 |