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    ARRB2 arrestin beta 2 [ Homo sapiens (human) ]

    Gene ID: 409, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Arrestin beta-2 deficiency exacerbates periodontal inflammation by mediating activating transcription factor 6 activation and abnormal remodelling of the extracellular matrix.

    Arrestin beta-2 deficiency exacerbates periodontal inflammation by mediating activating transcription factor 6 activation and abnormal remodelling of the extracellular matrix.
    Feng M, Wang R, Deng L, Yang Y, Xia S, Liu F, Luo L.

    07/15/2024
    A Common Variant of ARRB2 Promoter Region Associated with the Prognosis of Heart Failure.

    A Common Variant of ARRB2 Promoter Region Associated with the Prognosis of Heart Failure.
    Ren H, Liu Y, Tan Z, Luo G, Zhang M, Li S, Tang T, Zhao L.

    01/4/2024
    Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension.

    Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension.
    Wang L, Moonen JR, Cao A, Isobe S, Li CG, Tojais NF, Taylor S, Marciano DP, Chen PI, Gu M, Li D, Harper RL, El-Bizri N, Kim YM, Stankunas K, Rabinovitch M., Free PMC Article

    03/7/2023
    The Comprehensive Analysis of Hub Gene ARRB2 in Prostate Cancer.

    The Comprehensive Analysis of Hub Gene ARRB2 in Prostate Cancer.
    Zhou B, Song H, Xu W, Zhang Y, Liu Y, Qi W., Free PMC Article

    11/5/2022
    LncRNA GATA3-AS1 promoted invasion and migration in human endometrial carcinoma by regulating the miR-361/ARRB2 axis.

    LncRNA GATA3-AS1 promoted invasion and migration in human endometrial carcinoma by regulating the miR-361/ARRB2 axis.
    Liu YX, Yuan S, Liu XJ, Huang YX, Qiu P, Gao J, Deng GP.

    09/3/2022
    Association of polymorphisms in ARRB2 and clinical response to methadone for pain in advanced cancer.

    Association of polymorphisms in ARRB2 and clinical response to methadone for pain in advanced cancer.
    Ozberk D, Haywood A, Sutherland HG, Yu C, Albury CL, Zunk M, George R, Good P, Griffiths LR, Hardy J, Haupt LM.

    06/18/2022
    Biased Coupling to beta-Arrestin of Two Common Variants of the CB2 Cannabinoid Receptor.

    Biased Coupling to β-Arrestin of Two Common Variants of the CB(2) Cannabinoid Receptor.
    Turu G, Soltész-Katona E, Tóth AD, Juhász C, Cserző M, Misák Á, Balla A, Caron MG, Hunyady L., Free PMC Article

    04/30/2022
    beta-Arrestin 1 and 2 similarly influence mu-opioid receptor mobility and distinctly modulate adenylyl cyclase activity.

    β-Arrestin 1 and 2 similarly influence μ-opioid receptor mobility and distinctly modulate adenylyl cyclase activity.
    Markova V, Hejnova L, Benda A, Novotny J, Melkes B.

    04/9/2022
    Deficiency of beta-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in primary Sjogren's syndrome.

    Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in primary Sjögren's syndrome.
    Huang L, Liu Q, Zhou T, Zhang J, Tian Q, Zhang Q, Wei W, Wu H.

    03/12/2022
    Prokineticin receptors interact unselectively with several G protein subtypes but bind selectively to beta-arrestin 2.

    Prokineticin receptors interact unselectively with several G protein subtypes but bind selectively to β-arrestin 2.
    Casella I, Ambrosio C.

    01/22/2022
    Biphasic activation of beta-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR.

    Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR.
    Shiraishi Y, Kofuku Y, Ueda T, Pandey S, Dwivedi-Agnihotri H, Shukla AK, Shimada I., Free PMC Article

    01/22/2022
    Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade.

    Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade.
    Qu C, Park JY, Yun MW, He QT, Yang F, Kim K, Ham D, Li RR, Iverson TM, Gurevich VV, Sun JP, Chung KY., Free PMC Article

    12/25/2021
    In-frame fusion of SUMO1 enhances betaarrestin2's association with activated GPCRs as well as with nuclear pore complexes.

    In-frame fusion of SUMO1 enhances βarrestin2's association with activated GPCRs as well as with nuclear pore complexes.
    Nagi K, Kaur S, Bai Y, Shenoy SK.

    12/25/2021
    Arrb2 causes hepatic lipid metabolism disorder via AMPK pathway based on metabolomics in alcoholic fatty liver.

    Arrb2 causes hepatic lipid metabolism disorder via AMPK pathway based on metabolomics in alcoholic fatty liver.
    Sun YY, Wu DQ, Yin NN, Yang L, Chen X, Li HD, Li XF, Huang C, Meng XM, Wang H, Li J.

    11/22/2021
    The RanBP2/RanGAP1-SUMO complex gates beta-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis.

    The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis.
    Blondel-Tepaz E, Leverve M, Sokrat B, Paradis JS, Kosic M, Saha K, Auffray C, Lima-Fernandes E, Zamborlini A, Poupon A, Gaboury L, Findlay J, Baillie GS, Enslen H, Bouvier M, Angers S, Marullo S, Scott MGH.

    10/16/2021
    beta-Arrestin 2 Regulates Inflammatory Responses against Mycobacterium tuberculosis Infection through ERK1/2 Signaling.

    β-Arrestin 2 Regulates Inflammatory Responses against Mycobacterium tuberculosis Infection through ERK1/2 Signaling.
    Wen Q, Li Y, Han Z, Liu H, Zhang S, Chen Y, He J, Du X, Fu Y, Zhang L, Zhang Z, Huang Y, Zhou X, Zhou C, Hu S, Ma L.

    10/2/2021
    Host versus cell-dependent effects of beta-arrestin 1 expression in prostate tumorigenesis.

    Host versus cell-dependent effects of β-arrestin 1 expression in prostate tumorigenesis.
    Adekoya TO, Smith N, Thomas AJ, Lane TS, Burnette N, Rivers EJ, Li Y, Chen XL, Richardson RM., Free PMC Article

    10/2/2021
    Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling.

    Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling.
    Ceraudo E, Horioka M, Mattheisen JM, Hitchman TD, Moore AR, Kazmi MA, Chi P, Chen Y, Sakmar TP, Huber T., Free PMC Article

    08/28/2021
    beta-Arrestin 2 (ARRB2) Polymorphism is Associated With Adverse Consequences of Chronic Heroin Use.

    β-Arrestin 2 (ARRB2) Polymorphism is Associated With Adverse Consequences of Chronic Heroin Use.
    Karavidha KK, Burmeister M, Greenwald MK., Free PMC Article

    07/24/2021
    ARRB2 promotes colorectal cancer growth through triggering WTAP.

    ARRB2 promotes colorectal cancer growth through triggering WTAP.
    Liang H, Lin Z, Ye Y, Luo R, Zeng L.

    06/19/2021
    beta-arrestin 2 Is a Prognostic Factor for Survival of Ovarian Cancer Patients Upregulating Cell Proliferation.

    β-arrestin 2 Is a Prognostic Factor for Survival of Ovarian Cancer Patients Upregulating Cell Proliferation.
    Czogalla B, Partenheimer A, Jeschke U, von Schönfeldt V, Mayr D, Mahner S, Burges A, Simoni M, Melli B, Benevelli R, Bertini S, Casarini L, Trillsch F., Free PMC Article

    05/29/2021
    The role and mechanism of beta-arrestin2 in signal transduction.

    The role and mechanism of β-arrestin2 in signal transduction.
    Ma TL, Zhou Y, Zhang CY, Gao ZA, Duan JX.

    05/8/2021
    Identification of a beta-Arrestin 2 Mutation Related to Autism by Whole-Exome Sequencing.

    Identification of a β-Arrestin 2 Mutation Related to Autism by Whole-Exome Sequencing.
    Tang Y, Liu Y, Tong L, Feng S, Du D, Chen F., Free PMC Article

    03/20/2021
    GRK2-mediated receptor phosphorylation and Mdm2-mediated beta-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors.

    GRK2-mediated receptor phosphorylation and Mdm2-mediated β-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors.
    Zhang X, Zheng M, Kim KM.

    03/20/2021
    SUMOylation involves in beta-arrestin-2-dependent metabolic regulation in breast cancer cell.

    SUMOylation involves in β-arrestin-2-dependent metabolic regulation in breast cancer cell.
    Dong C, Li Y, Niu Q, Fang H, Bai J, Yan Y, Gu C, Xiao N.

    02/13/2021
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