| Knockdown of MAGE-A6 enhanced the irradiation sensitivity of non-small cell lung cancer cells by activating the AMPK pathway. | Knockdown of MAGE-A6 enhanced the irradiation sensitivity of non-small cell lung cancer cells by activating the AMPK pathway.
Zhou J, Fan Q, Li J, Wu J, Huang J, Zhang Y, He X. | 06/18/2022 |
| Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer. | Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer.
Mohsenzadegan M, Razmi M, Vafaei S, Abolhasani M, Madjd Z, Saeednejad Zanjani L, Sharifi L., Free PMC Article | 03/5/2022 |
| Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression. | Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression.
Tsang YH, Wang Y, Kong K, Grzeskowiak C, Zagorodna O, Dogruluk T, Lu H, Villafane N, Bhavana VH, Moreno D, Elsea SH, Liang H, Mills GB, Scott KL., Free PMC Article | 04/3/2021 |
| Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling. | Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling.
Xue J, Zhong S, Sun BM, Sun QF, Hu LY, Pan SJ., Free PMC Article | 08/29/2020 |
| data indicate that the activation of CT-GABRA3 is correlated with that of MAGEA6. Therefore, MAGEA6 is linked with CT-GABRA3 through a bidirectional promoter. | Epigenetic Coactivation of MAGEA6 and CT-GABRA3 Defines Orientation of a Segmental Duplication in the Human X Chromosome.
Fain JS, Van Tongelen A, Loriot A, De Smet C. | 12/7/2019 |
| High MAGEA6 expression is associated with recurrence in Gastric Cancer. | Tissue Expression of Melanoma-associated Antigen A6 and Clinical Characteristics of Gastric Cancer.
Endo M, Kanda M, Sawaki K, Shimizu D, Tanaka C, Kobayashi D, Hattori N, Hayashi M, Yamada S, Koike M, Omae K, Kodera Y. | 11/30/2019 |
| Data indicate that miR-1273g represses melanoma antigen family A 3/melanoma antigen family A 6 (MAGEA3/6 )expression in colorectal cancer (CRC) cells and tissues, which may suggest a cancer-specific therapeutic. | miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling.
Wu F, Liu F, Dong L, Yang H, He X, Li L, Zhao L, Jin S, Li G. | 09/28/2019 |
| MAGEA6 knockdown by targeted-shRNA induced AMPK stabilization and activation, which led to mTOR complex 1 (mTORC1) in-activation and RCC cell death/apoptosis. | Knockdown of MAGEA6 Activates AMP-Activated Protein Kinase (AMPK) Signaling to Inhibit Human Renal Cell Carcinoma Cells.
Ye X, Xie J, Huang H, Deng Z. | 03/24/2018 |
| MAGEA6 promotes glioma cell survival possibly via targeting AMPKalpha1. | MAGEA6 promotes human glioma cell survival via targeting AMPKα1.
Pan SJ, Ren J, Jiang H, Liu W, Hu LY, Pan YX, Sun B, Sun QF, Bian LG. | 12/9/2017 |
| MageA6 and MageA11 form a protein complex resulting in the stabilization of MageA11 and consequently the enhancement of androgen receptor activity. | Functional interaction between co-expressed MAGE-A proteins.
Laiseca JE, Ladelfa MF, Cotignola J, Peche LY, Pascucci FA, Castaño BA, Galigniana MD, Schneider C, Monte M., Free PMC Article | 09/23/2017 |
| MAGEA3/6 positivity was associated with significantly better disease-free survival. | A Comprehensive Expression Analysis of Cancer Testis Antigens in Head and Neck Squamous Cell Carcinoma Revels MAGEA3/6 as a Marker for Recurrence.
Zamunér FT, Karia BT, de Oliveira CZ, Santos CR, Carvalho AL, Vettore AL. | 03/19/2016 |
| Study describes a widespread mechanism to suppress AMPK through its ubiquitination and degradation by the cancer-specific MAGE-A3/6-TRIM28 ubiquitin ligase. MAGE-A3 and MAGE-A6 are highly similar proteins normally expressed only in the male germline but frequently re-activated in human cancers. | Degradation of AMPK by a cancer-specific ubiquitin ligase.
Pineda CT, Ramanathan S, Fon Tacer K, Weon JL, Potts MB, Ou YH, White MA, Potts PR., Free PMC Article | 04/11/2015 |
| To identify novel CTL epitopes from MAGE-A6 and MAGE-A12 antigens. | Identification of novel MAGE-A6- and MAGE-A12-derived HLA-A24-restricted cytotoxic T lymphocyte epitopes using an in silico peptide-docking assay.
Akiyama Y, Komiyama M, Nakamura Y, Iizuka A, Oshita C, Kume A, Nogami M, Miyata H, Ashizawa T, Yoshikawa S, Kiyohara Y, Yamaguchi K., Free PMC Article | 05/11/2013 |
| Report MAGEA1-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells. | MAGE A1-A6 RT-PCR and MAGE A3 and p16 methylation analysis in induced sputum from patients with lung cancer and non-malignant lung diseases.
Shin KC, Lee KH, Lee CH, Shin IH, Suh HS, Jeon CH., Free PMC Article | 06/2/2012 |
| Multiple simultaneous detection of MAGE-A [subtypes] more specific and sensitive than detection of single MAGE-A antigen for the diagnostic and prognostic evaluation of oral squamous cell carcinoma | Expression of melanoma-associated antigens in oral squamous cell carcinoma.
Ries J, Vairaktaris E, Mollaoglu N, Wiltfang J, Neukam FW, Nkenke E. | 01/21/2010 |
| MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma | MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.
Tatsumi T, Kierstead LS, Ranieri E, Gesualdo L, Schena FP, Finke JH, Bukowski RM, Brusic V, Sidney J, Sette A, Logan TF, Kasamon YL, Slingluff CL Jr, Kirkwood JM, Storkus WJ. | 01/21/2010 |
| Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma. | Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma.
Tatsumi T, Kierstead LS, Ranieri E, Gesualdo L, Schena FP, Finke JH, Bukowski RM, Mueller-Berghaus J, Kirkwood JM, Kwok WW, Storkus WJ., Free PMC Article | 01/21/2010 |