| RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis. | RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis.
Guan Z, Li H, Zhang C, Huang Z, Ye M, Zhang Y, Li S, Peng K., Free PMC Article | 09/5/2024 |
| TCEB3 initiates ovarian cancer apoptosis by mediating ubiquitination and degradation of MCL-1. | TCEB3 initiates ovarian cancer apoptosis by mediating ubiquitination and degradation of MCL-1.
Cai Y, Li Y, Xu Y, Yang W, Huang M. | 05/17/2024 |
| Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization. | Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization.
McAloney CA, Makkawi R, Budhathoki Y, Cannon MV, Franz EM, Gross AC, Cam M, Vetter TA, Duhen R, Davies AE, Roberts RD., Free PMC Article | 03/1/2024 |
| Mcl-1 Protein and Viral Infections: A Narrative Review. | Mcl-1 Protein and Viral Infections: A Narrative Review.
Wyżewski Z, Stępkowska J, Kobylińska AM, Mielcarska A, Mielcarska MB., Free PMC Article | 02/28/2024 |
| FBXW7 affects autophagy through MCL1 in oral squamous cell carcinoma. | FBXW7 affects autophagy through MCL1 in oral squamous cell carcinoma.
Sun Y, Nie W, Qiu B, Yang Q, Zhao H. | 12/15/2023 |
| Myeloid cell leukemia-1 as a candidate prognostic biomarker in cancers: a systematic review and meta-analysis. | Myeloid cell leukemia-1 as a candidate prognostic biomarker in cancers: a systematic review and meta-analysis.
Wang J, He Y, Yang C, Luo Q, Wang B. | 11/3/2023 |
| MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients. | MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients.
Catalano G, Zaza A, Banella C, Pelosi E, Castelli G, de Marinis E, Smigliani A, Travaglini S, Ottone T, Divona M, Del Principe MI, Buccisano F, Maurillo L, Ammatuna E, Testa U, Nervi C, Venditti A, Voso MT, Noguera NI. | 08/9/2023 |
| Polypyrimidine tract binding protein 1 (PTBP1) contains a novel regulatory sequence, the rBH3, that binds the prosurvival protein MCL1. | Polypyrimidine tract binding protein 1 (PTBP1) contains a novel regulatory sequence, the rBH3, that binds the prosurvival protein MCL1.
Carico C, Cui J, Acton A, Placzek WJ., Free PMC Article | 07/12/2023 |
| SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication. | SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication.
Pan P, Ge W, Lei Z, Luo W, Liu Y, Guan Z, Chen L, Yu Z, Shen M, Hu D, Xiang Q, Wang W, Wan P, Tian M, Yu Y, Luo Z, Chen X, Xiao H, Zhang Q, Liang X, Chen X, Li Y, Wu J., Free PMC Article | 05/11/2023 |
| Dual targeting of BCL-2 and MCL-1 in the presence of BAX breaks venetoclax resistance in human small cell lung cancer. | Dual targeting of BCL-2 and MCL-1 in the presence of BAX breaks venetoclax resistance in human small cell lung cancer.
Valko Z, Megyesfalvi Z, Schwendenwein A, Lang C, Paku S, Barany N, Ferencz B, Horvath-Rozsas A, Kovacs I, Schlegl E, Pozonec V, Boettiger K, Rezeli M, Marko-Varga G, Renyi-Vamos F, Hoda MA, Klikovits T, Hoetzenecker K, Grusch M, Laszlo V, Dome B, Schelch K., Free PMC Article | 05/8/2023 |
| Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation. | Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation.
Thus YJ, De Rooij MFM, Swier N, Beijersbergen RL, Guikema JEJ, Kersten MJ, Eldering E, Pals ST, Kater AP, Spaargaren M., Free PMC Article | 03/2/2023 |
| N6-methyladenosine modification in trophoblasts promotes circSETD2 expression, inhibits miR-181a-5p, and elevates MCL1 transcription to reduce apoptosis of trophoblasts. | N6-methyladenosine modification in trophoblasts promotes circSETD2 expression, inhibits miR-181a-5p, and elevates MCL1 transcription to reduce apoptosis of trophoblasts.
Wang D, Guan H, Wang Y, Song G, Xia Y. | 02/14/2023 |
| Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies. | Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies.
Tantawy SI, Sarkar A, Hubner S, Tan Z, Wierda WG, Eldeib A, Zhang S, Kornblau S, Gandhi V., Free PMC Article | 01/21/2023 |
| Stabilization of MCL-1 by E3 ligase TRAF4 confers radioresistance. | Stabilization of MCL-1 by E3 ligase TRAF4 confers radioresistance.
Li M, Gao F, Li X, Gan Y, Han S, Yu X, Liu H, Li W., Free PMC Article | 12/31/2022 |
| Expression Ratios of the Antiapoptotic BCL2 Family Members Dictate the Selective Addiction of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Primary Effusion Lymphoma Cell Lines to MCL1. | Expression Ratios of the Antiapoptotic BCL2 Family Members Dictate the Selective Addiction of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Primary Effusion Lymphoma Cell Lines to MCL1.
Dunham D, Viswanathan P, Gill J, Manzano M., Free PMC Article | 12/24/2022 |
| Downregulation of Circ-CEP128 Enhances the Paclitaxel Sensitivity of Cervical Cancer Through Regulating miR-432-5p/MCL1. | Downregulation of Circ-CEP128 Enhances the Paclitaxel Sensitivity of Cervical Cancer Through Regulating miR-432-5p/MCL1.
Zhao Y, Lan Y, Chi Y, Yang B, Ren C. | 11/5/2022 |
| FOXO1 represses MCL1 transcription to regulate the function of vascular smooth muscle cells in intracranial aneurysm. | FOXO1 represses MCL1 transcription to regulate the function of vascular smooth muscle cells in intracranial aneurysm.
Huang J, Hong L, Shen B, Zhou Y, Lan J, Peng Y. | 10/29/2022 |
| Targeting of MCL-1 in breast cancer-associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties. | Targeting of MCL-1 in breast cancer-associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties.
Bonneaud TL, Lefebvre CC, Nocquet L, Basseville A, Roul J, Weber H, Campone M, Juin PP, Souazé F., Free PMC Article | 10/1/2022 |
| MCL1 as putative target in pancreatoblastoma. | MCL1 as putative target in pancreatoblastoma.
Reissig TM, Uhrig S, Jost PJ, Luchini C, Vicentini C, Liffers ST, Allgäuer M, Adsay V, Scarpa A, Lawlor RT, Fröhling S, Stenzinger A, Klöppel G, Schildhaus HU, Siveke JT., Free PMC Article | 08/13/2022 |
| Mutation in MCL1 predicted loop to helix structural transition stabilizes MCL1-Bax binding interaction favoring cancer cell survival. | Mutation in MCL1 predicted loop to helix structural transition stabilizes MCL1-Bax binding interaction favoring cancer cell survival.
Deepak Shyl ES, Malgija B, Iniyan AM, Vincent SGP. | 08/13/2022 |
| miR-181c regulates MCL1 and cell survival in GATA2 deficient cells. | miR-181c regulates MCL1 and cell survival in GATA2 deficient cells.
Wang W, Chen R, Droll S, Barber E, Saleh L, Corrigan-Cummins M, Trick M, Anastas V, Hawk NV, Zhao Z, Vinh DC, Hsu A, Hickstein DD, Holland SM, Calvo KR., Free PMC Article | 05/21/2022 |
| Mcl-1 levels critically impact the sensitivities of human colorectal cancer cells to APG-1252-M1, a novel Bcl-2/Bcl-XL dual inhibitor that induces Bax-dependent apoptosis. | Mcl-1 levels critically impact the sensitivities of human colorectal cancer cells to APG-1252-M1, a novel Bcl-2/Bcl-X(L) dual inhibitor that induces Bax-dependent apoptosis.
Yao W, Bai L, Wang S, Zhai Y, Sun SY., Free PMC Article | 05/14/2022 |
| Targeting of Mcl-1 Expression by MiRNA-3614-5p Promotes Cell Apoptosis of Human Prostate Cancer Cells. | Targeting of Mcl-1 Expression by MiRNA-3614-5p Promotes Cell Apoptosis of Human Prostate Cancer Cells.
Hsieh YH, Yu FJ, Nassef Y, Liu CJ, Chen YS, Lin CY, Feng JL, Wu MH., Free PMC Article | 04/30/2022 |
| Increased MCL-1 synthesis promotes irradiation-induced nasopharyngeal carcinoma radioresistance via regulation of the ROS/AKT loop. | Increased MCL-1 synthesis promotes irradiation-induced nasopharyngeal carcinoma radioresistance via regulation of the ROS/AKT loop.
Liang YY, Niu FY, Xu AA, Jiang LL, Liu CS, Liang HP, Huang YF, Shao XF, Mo ZW, Yuan YW., Free PMC Article | 04/16/2022 |
| MCL1 nuclear translocation induces chemoresistance in colorectal carcinoma. | MCL1 nuclear translocation induces chemoresistance in colorectal carcinoma.
Fu D, Pfannenstiel L, Demelash A, Phoon YP, Mayell C, Cabrera C, Liu C, Zhao J, Dermawan J, Patil D, DeVecchio J, Kalady M, Souers AJ, Phillips DC, Li X, Gastman B., Free PMC Article | 04/16/2022 |