| Regulation of cytokine and chemokine expression by histone lysine methyltransferase MLL1 in rheumatoid arthritis synovial fibroblasts. | Regulation of cytokine and chemokine expression by histone lysine methyltransferase MLL1 in rheumatoid arthritis synovial fibroblasts.
Okamoto K, Araki Y, Aizaki Y, Tanaka S, Kadono Y, Mimura T., Free PMC Article | 06/5/2024 |
| Impact of MLL::AF9 Gene Rearrangement on Survival of Acute Myeloid Leukaemia Patients: An Insight into Pakistani Population. | Impact of MLL::AF9 Gene Rearrangement on Survival of Acute Myeloid Leukaemia Patients: An Insight into Pakistani Population.
Tariq M, Shahab S, Saeed JR, Hussain Z, Zaidi U, Farzana T, Ahmad S. | 04/12/2024 |
| Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth. | Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth.
Wu J, Qin C, Tian F, Liu X, Hu J, Wu F, Chen C, Lin Y., Free PMC Article | 03/11/2024 |
| Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A::AFF1 fusion. | Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A::AFF1 fusion.
Tretti Parenzan C, Molin AD, Longo G, Gaffo E, Buratin A, Cani A, Boldrin E, Serafin V, Guglielmelli P, Vannucchi AM, Cazzaniga G, Biondi A, Locatelli F, Meyer LH, Buldini B, Te Kronnie G, Bresolin S, Bortoluzzi S., Free PMC Article | 03/5/2024 |
| Two cases of mycosis fungoides with large cell transformation with KMT2A rearrangements. | Two cases of mycosis fungoides with large cell transformation with KMT2A rearrangements.
Wadsworth PA, Lawrence L, Suarez CJ, Saleem A, Khodadoust MS, Kim YH, Rieger KE, Fernandez-Pol S. | 01/8/2024 |
| Dependency of B-Cell Acute Lymphoblastic Leukemia and Multiple Myeloma Cell Lines on MEN1 Extends beyond MEN1-KMT2A Interaction. | Dependency of B-Cell Acute Lymphoblastic Leukemia and Multiple Myeloma Cell Lines on MEN1 Extends beyond MEN1-KMT2A Interaction.
Wolffhardt TM, Ketzer F, Telese S, Wirth T, Ushmorov A., Free PMC Article | 12/4/2023 |
| Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer. | Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer.
Lin X, Chen JD, Wang CY, Cai Z, Zhan R, Yang C, Zhang LY, Li LY, Xiao Y, Chen MK, Wu M., Free PMC Article | 12/1/2023 |
| Miliary leukemia cutis as extramedullary relapse of KMT2A rearranged pediatric AML. | Miliary leukemia cutis as extramedullary relapse of KMT2A rearranged pediatric AML.
Muratore E, Belotti T, Gottardi F, Sagramoso C, Prete A, Masetti R. | 11/2/2023 |
| MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1. | MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1.
Zhang C, Ye W, Zhao M, Long L, Xia D, Fan Z., Free PMC Article | 10/30/2023 |
| Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement. | Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement.
Gray ZH, Chakraborty D, Duttweiler RR, Alekbaeva GD, Murphy SE, Chetal K, Ji F, Ferman BI, Honer MA, Wang Z, Myers C, Sun R, Kaniskan HÜ, Toma MM, Bondarenko EA, Santoro JN, Miranda C, Dillingham ME, Tang R, Gozani O, Jin J, Skorski T, Duy C, Lee H, Sadreyev RI, Whetstine JR., | 10/30/2023 |
| Comparison of minimal residual disease measurement by multicolour flow cytometry and PCR for fusion gene transcripts in infants with acute lymphoblastic leukaemia with KMT2A gene rearrangements. | Comparison of minimal residual disease measurement by multicolour flow cytometry and PCR for fusion gene transcripts in infants with acute lymphoblastic leukaemia with KMT2A gene rearrangements.
Popov A, Tsaur G, Verzhbitskaya T, Riger T, Permikin Z, Demina A, Mikhailova E, Shorikov E, Arakaev O, Streneva O, Khlebnikova O, Makarova O, Miakova N, Fominikh V, Boichenko E, Kondratchik K, Ponomareva N, Novichkova G, Karachunskiy A, Fechina L. | 10/20/2023 |
| Rearrangement of KMT2A Characterizes a Subset of Pediatric Parotid Mucoepidermoid Carcinomas Arising Metachronous to Acute Lymphoblastic Leukemia. | Rearrangement of KMT2A Characterizes a Subset of Pediatric Parotid Mucoepidermoid Carcinomas Arising Metachronous to Acute Lymphoblastic Leukemia.
Othman BK, Steiner P, Leivo I, Skálová A. | 09/20/2023 |
| MLL methyltransferases regulate H3K4 methylation to ensure CENP-A assembly at human centromeres. | MLL methyltransferases regulate H3K4 methylation to ensure CENP-A assembly at human centromeres.
Malik KK, Sridhara SC, Lone KA, Katariya PD, Pulimamidi D, Tyagi S., Free PMC Article | 07/19/2023 |
| KMT2A is targeted by miR-361-3p and modulates leukemia cell's abilities to proliferate, migrate and invade. | KMT2A is targeted by miR-361-3p and modulates leukemia cell's abilities to proliferate, migrate and invade.
Xu D, Jiang J, He G, Zhou H, Ji C. | 06/26/2023 |
| The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome. | The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome.
Külp M, Larghero P, Alten J, Cario G, Eckert C, Caye-Eude A, Cavé H, Schmachtel T, Bardini M, Cazzaniga G, De Lorenzo P, Valsecchi MG, Bonig H, Meyer C, Rieger MA, Marschalek R., Free PMC Article | 06/13/2023 |
| Early mortality in acute myeloid leukemia with KMT2A rearrangement is associated with high risk of bleeding and disseminated intravascular coagulation. | Early mortality in acute myeloid leukemia with KMT2A rearrangement is associated with high risk of bleeding and disseminated intravascular coagulation.
Nguyen D, Kantarjian HM, Short NJ, Qiao W, Ning J, Cuglievan B, Daver NG, DiNardo CD, Jabbour EJ, Kadia TM, Borthakur G, Garcia-Manero G, Konopleva MY, Andreeff M, Ravandi-Kashani F, Sasaki K, Issa GC. | 05/23/2023 |
| The epileptology of Wiedemann-Steiner syndrome: Electroclinical findings in five patients with KMT2A pathogenic variants. | The epileptology of Wiedemann-Steiner syndrome: Electroclinical findings in five patients with KMT2A pathogenic variants.
Sahly AN, Srour M, Buhas D, Scheffer IE, Myers KA. | 05/22/2023 |
| The KMT2A recombinome of acute leukemias in 2023. | The KMT2A recombinome of acute leukemias in 2023.
Meyer C, Larghero P, Almeida Lopes B, Burmeister T, Gröger D, Sutton R, Venn NC, Cazzaniga G, Corral Abascal L, Tsaur G, Fechina L, Emerenciano M, Pombo-de-Oliveira MS, Lund-Aho T, Lundán T, Montonen M, Juvonen V, Zuna J, Trka J, Ballerini P, Lapillonne H, Van der Velden VHJ, Sonneveld E, Delabesse E, de Matos RRC, Silva MLM, Bomken S, Katsibardi K, Keernik M, Grardel N, Mason J, Price R, Kim J, Eckert C, Lo Nigro L, Bueno C, Menendez P, Zur Stadt U, Gameiro P, Sedék L, Szczepański T, Bidet A, Marcu V, Shichrur K, Izraeli S, Madsen HO, Schäfer BW, Kubetzko S, Kim R, Clappier E, Trautmann H, Brüggemann M, Archer P, Hancock J, Alten J, Möricke A, Stanulla M, Lentes J, Bergmann AK, Strehl S, Köhrer S, Nebral K, Dworzak MN, Haas OA, Arfeuille C, Caye-Eude A, Cavé H, Marschalek R., Free PMC Article | 05/12/2023 |
| Blinatumomab Added to Chemotherapy in Infant Lymphoblastic Leukemia. | Blinatumomab Added to Chemotherapy in Infant Lymphoblastic Leukemia.
van der Sluis IM, de Lorenzo P, Kotecha RS, Attarbaschi A, Escherich G, Nysom K, Stary J, Ferster A, Brethon B, Locatelli F, Schrappe M, Scholte-van Houtem PE, Valsecchi MG, Pieters R. | 04/29/2023 |
| RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Blatter M, Meylan C, Cléry A, Giambruno R, Nikolaev Y, Heidecker M, Solanki JA, Diaz MO, Gabellini D, Allain FH., Free PMC Article | 04/24/2023 |
| The adverse impact of ecotropic viral integration site-1 (EVI1) overexpression on the prognosis of acute myeloid leukemia with KMT2A gene rearrangement in different risk stratification subtypes. | The adverse impact of ecotropic viral integration site-1 (EVI1) overexpression on the prognosis of acute myeloid leukemia with KMT2A gene rearrangement in different risk stratification subtypes.
Liu XX, Pan XA, Gao MG, Kong J, Jiang H, Chang YJ, Zhang XH, Wang Y, Liu KY, Chen Z, Zhao XS, Huang XJ. | 03/24/2023 |
| Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes. | Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes.
Casado P, Rio-Machin A, Miettinen JJ, Bewicke-Copley F, Rouault-Pierre K, Krizsan S, Parsons A, Rajeeve V, Miraki-Moud F, Taussig DC, Bödör C, Gribben J, Heckman C, Fitzgibbon J, Cutillas PR., Free PMC Article | 03/1/2023 |
| The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. | The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation.
Sharma SB, Melvin WJ, Audu CO, Bame M, Rhoads N, Wu W, Kanthi Y, Knight JS, Adili R, Holinstat MA, Wakefield TW, Henke PK, Moore BB, Gallagher KA, Obi AT., Free PMC Article | 02/24/2023 |
| DNA fragility at the KMT2A/MLL locus: insights from old and new technologies. | DNA fragility at the KMT2A/MLL locus: insights from old and new technologies.
Cowell IG, Austin CA., Free PMC Article | 02/11/2023 |
| The KMT2A rearrangement is an early event prior to KMT2A-PTD in AML patients with both molecular aberrations. | The KMT2A rearrangement is an early event prior to KMT2A-PTD in AML patients with both molecular aberrations.
Huang J, Zhu Y, Li J, Yang G, Zhang S. | 02/11/2023 |