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    MMP10 matrix metallopeptidase 10 [ Homo sapiens (human) ]

    Gene ID: 4319, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Identification of a functional missense variant in the matrix metallopeptidase 10 (MMP10) gene in two families with premature myocardial infarction.

    Identification of a functional missense variant in the matrix metallopeptidase 10 (MMP10) gene in two families with premature myocardial infarction.
    Verovenko V, Tennstedt S, Kleinecke M, Kessler T, Schunkert H, Erdmann J, Ensminger S, Aherrahrou Z., Free PMC Article

    06/5/2024
    Matrix metalloproteinase-10 deficiency has protective effects against peritoneal inflammation and fibrosis via transcription factor NFkappaBeta pathway inhibition.

    Matrix metalloproteinase-10 deficiency has protective effects against peritoneal inflammation and fibrosis via transcription factor NFκΒ pathway inhibition.
    Ishimura T, Ishii A, Yamada H, Osaki K, Toda N, Mori KP, Ohno S, Kato Y, Handa T, Sugioka S, Ikushima A, Nishio H, Yanagita M, Yokoi H.

    12/15/2023
    The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility.

    The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility.
    Zhao Y, Zhang Q, Zhang X, Zhang Y, Lu Y, Ma X, Li W, Niu X, Zhang G, Chang M, Shi W, Tian Y., Free PMC Article

    12/31/2022
    Higher Content but Not Activity of Stromelysin-2 (MMP-10) in Comparison to Stromelysin-1 (MMP-3) in Human Renal Carcinoma.

    Higher Content but Not Activity of Stromelysin-2 (MMP-10) in Comparison to Stromelysin-1 (MMP-3) in Human Renal Carcinoma.
    Kudelski J, Młynarczyk G, Gudowska-Sawczuk M, Mroczko B, Darewicz B, Bruczko-Goralewska M, Romanowicz L., Free PMC Article

    10/22/2022
    Study on the Mechanism of circRNA-0024103 Reducing Endothelial Cell Injury by Regulating miR-363/MMP-10.

    Study on the Mechanism of circRNA-0024103 Reducing Endothelial Cell Injury by Regulating miR-363/MMP-10.
    Tian Y, Zheng G, Xie H, Guo Y, Zeng H, Fu Y, Liu X., Free PMC Article

    09/17/2022
    Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type.

    Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type.
    Martino Adami PV, Orellana A, García P, Kleineidam L, Alarcón-Martín E, Montrreal L, Aguilera N, Espinosa A, Abdelnour C, Rosende-Roca M, Pablo Tartari J, Vargas L, Mauleón A, Esteban-De Antonio E, López-Cuevas R, Dalmasso MC, Campos Martin R, Parveen K, Andrade Fuentes VM, Amin N, Ahmad S, Ikram MA, Lewczuk P, Kornhuber J, Peters O, Frölich L, Rüther E, Wiltfang J, Tarraga L, Boada M, Maier W, de Rojas I, Cano A, Sanabria A, Alegret M, Hernández I, Marquié M, Valero S, van Duijn CM, Wagner M, Jessen F, Schneider A, Sáez Goñi ME, González Pérez A, Ruiz A, Ramírez A.

    08/6/2022
    MicroRNA-152 Regulates Endometrial Serous Carcinoma Cell Motility by Suppressing Matrix Metalloproteinase 10 Expression.

    MicroRNA-152 Regulates Endometrial Serous Carcinoma Cell Motility by Suppressing Matrix Metalloproteinase 10 Expression.
    Shigeta S, Watanabe Y, Suzuki F, Nagase S, Shibuya Y, Ishibashi M, Nagai T, Shiga N, Toyoshima M, Tokunaga H, Shimada M, Yaegashi N.

    07/9/2022
    Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19.

    Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19.
    Soares-Schanoski A, Sauerwald N, Goforth CW, Periasamy S, Weir DL, Lizewski S, Lizewski R, Ge Y, Kuzmina NA, Nair VD, Vangeti S, Marjanovic N, Cappuccio A, Cheng WS, Mofsowitz S, Miller CM, Yu XB, George MC, Zaslavsky E, Bukreyev A, Troyanskaya OG, Sealfon SC, Letizia AG, Ramos I., Free PMC Article

    05/7/2022
    miR-496/MMP10 Is Involved in the Proliferation of IL-1beta-Induced Fibroblast-Like Synoviocytes Via Mediating the NF-kappaB Signaling Pathway.

    miR-496/MMP10 Is Involved in the Proliferation of IL-1β-Induced Fibroblast-Like Synoviocytes Via Mediating the NF-κB Signaling Pathway.
    Xing XW, Shi HY, Liu S, Feng SX, Feng SQ, Gong BQ.

    12/25/2021
    Identification of matrix metalloproteinase-10 as a key mediator of podocyte injury and proteinuria.

    Identification of matrix metalloproteinase-10 as a key mediator of podocyte injury and proteinuria.
    Zuo Y, Wang C, Sun X, Hu C, Liu J, Hong X, Shen W, Nie J, Hou FF, Zhou L, Liu Y.

    10/23/2021
    MMP-10 rs17435959 Polymorphism is Associated with the Formation and Stability of Carotid Atherosclerosis Plaque: A Case-Control Study.

    MMP-10 rs17435959 Polymorphism is Associated with the Formation and Stability of Carotid Atherosclerosis Plaque: A Case-Control Study.
    Wu LN, Wang WF, Wang XW, Li WL, Luo S, Ni H, Zheng HB, Hong WJ, Jiang YQ, Zhu F.

    10/23/2021
    Matrix metalloproteinase-10 protects against acute kidney injury by augmenting epidermal growth factor receptor signaling.

    Matrix metalloproteinase-10 protects against acute kidney injury by augmenting epidermal growth factor receptor signaling.
    Hu C, Zuo Y, Ren Q, Sun X, Zhou S, Liao J, Hong X, Miao J, Zhou L, Liu Y., Free PMC Article

    10/2/2021
    Matrix Metalloproteinase Genes (MMP1, MMP10, MMP12) on Chromosome 11q22 and the Risk of Non-Contact Anterior Cruciate Ligament Ruptures.

    Matrix Metalloproteinase Genes (MMP1, MMP10, MMP12) on Chromosome 11q22 and the Risk of Non-Contact Anterior Cruciate Ligament Ruptures.
    Lulińska E, Gibbon A, Kaczmarczyk M, Maciejewska-Skrendo A, Ficek K, Leońska-Duniec A, Wilk M, Leźnicka K, Michałowska-Sawczyn M, Humińska-Lisowska K, Buryta R, Cięszczyk P, Maculewicz E, Czarny W, September AV, Sawczuk M., Free PMC Article

    03/20/2021
    Expression of Matrix Metalloproteinases and Their Inhibitors in Endometrium: High Levels in Endometriotic Lesions.

    Expression of Matrix Metalloproteinases and Their Inhibitors in Endometrium: High Levels in Endometriotic Lesions.
    Luddi A, Marrocco C, Governini L, Semplici B, Pavone V, Luisi S, Petraglia F, Piomboni P., Free PMC Article

    02/6/2021
    MMP-10 is Increased in Early Stage Diabetic Kidney Disease and can be Reduced by Renin-Angiotensin System Blockade.

    MMP-10 is Increased in Early Stage Diabetic Kidney Disease and can be Reduced by Renin-Angiotensin System Blockade.
    Mora-Gutiérrez JM, Rodríguez JA, Fernández-Seara MA, Orbe J, Escalada FJ, Soler MJ, Slon Roblero MF, Riera M, Páramo JA, Garcia-Fernandez N., Free PMC Article

    11/21/2020
    MMP-10, which is overexpressed in aortic valve from patients with calcific aortic stenosis, seems to play a central role in calcification in AS through Akt phosphorylation.

    A Role for MMP-10 (Matrix Metalloproteinase-10) in Calcific Aortic Valve Stenosis.
    Matilla L, Roncal C, Ibarrola J, Arrieta V, García-Peña A, Fernández-Celis A, Navarro A, Álvarez V, Gainza A, Orbe J, Cachofeiro V, Zalba G, Sádaba R, Rodríguez JA, López-Andrés N.

    07/18/2020
    Our results suggest that MMP-10 facilitates H. pylori persistence and promotes gastritis.

    Helicobacter pylori-induced matrix metallopeptidase-10 promotes gastric bacterial colonization and gastritis.
    Lv YP, Cheng P, Zhang JY, Mao FY, Teng YS, Liu YG, Kong H, Wu XL, Hao CJ, Han B, Ma Q, Yang SM, Chen W, Peng LS, Wang TT, Zou QM, Zhuang Y., Free PMC Article

    05/2/2020
    study provides new insights into the role that MMP2 and MMP10 plays in the mechanism of Steroid-Induced Osteonecrosis of the Femoral Head.

    MMP2 and MMP10 Polymorphisms Are Related to Steroid-Induced Osteonecrosis of the Femoral Head among Chinese Han Population.
    Tian Y, An F, Wang J, Liu C, Wu H, Cao Y, Wang J, Wang G., Free PMC Article

    12/7/2019
    MMP10 plays a role in atherosclerosis, favoring inflammation, development and complication of the plaque

    Matrix metalloproteinase-10 deficiency delays atherosclerosis progression and plaque calcification.
    Purroy A, Roncal C, Orbe J, Meilhac O, Belzunce M, Zalba G, Villa-Bellosta R, Andrés V, Parks WC, Páramo JA, Rodríguez JA.

    11/23/2019
    increased abundance of Snail and Axin2 is highly correlated to malignant transformation of OL, making them novel biomarker(s) predicting oral cancer development

    Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases.
    Upadhyay P, Gardi N, Desai S, Chandrani P, Joshi A, Dharavath B, Arora P, Bal M, Nair S, Dutt A., Free PMC Article

    06/16/2018
    MMP10, either alone or in combination with tPA, might represent a new strategy for thrombolysis in ischemic stroke, providing higher protection against cerebrovascular damage.

    New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator.
    Roncal C, Martinez de Lizarrondo S, Salicio A, Chevilley A, Rodriguez JA, Rosell A, Couraud PO, Weksler B, Montaner J, Vivien D, Páramo JA, Orbe J.

    05/26/2018
    There is a significant association in the expression of P-Rex1 and MMP10 in human luminal breast cancer, and their co-expression is indicative of poor prognosis.

    Characterization of a P-Rex1 gene signature in breast cancer cells.
    Barrio-Real L, Wertheimer E, Garg R, Abba MC, Kazanietz MG., Free PMC Article

    02/10/2018
    MMP10 is a novel marker for cancer stem-like cells (CSCs)/cancer-initiating cells in epithelial ovarian cancer

    Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer.
    Mariya T, Hirohashi Y, Torigoe T, Tabuchi Y, Asano T, Saijo H, Kuroda T, Yasuda K, Mizuuchi M, Saito T, Sato N., Free PMC Article

    01/6/2018
    Data show that AJUBA upregulated MMP10 and MMP13 expression in esophageal squamous cell carcinoma (ESCC).

    AJUBA promotes the migration and invasion of esophageal squamous cell carcinoma cells through upregulation of MMP10 and MMP13 expression.
    Shi X, Chen Z, Hu X, Luo M, Sun Z, Li J, Shi S, Feng X, Zhou C, Li Z, Yang W, Li Y, Wang P, Zhou F, Gao Y, He J., Free PMC Article

    12/30/2017
    MMP10 is overexpressed in the serum and pulmonary arteries of patients with systemic sclerosis-associated pulmonary hypertension.

    Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis.
    Avouac J, Guignabert C, Hoffmann-Vold AM, Ruiz B, Dorfmuller P, Pezet S, Amar O, Tu L, Van Wassenhove J, Sadoine J, Launay D, Elhai M, Cauvet A, Subramaniam A, Resnick R, Hachulla E, Molberg Ø, Kahan A, Humbert M, Allanore Y.

    11/11/2017
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